arXiv subjects

Lan Ma

Publications and source records attributed to Lan Ma.

44 records · Page 3Linked to original sources

arXiv2022

Mixed-UNet: Refined Class Activation Mapping for Weakly-Supervised Semantic Segmentation with Multi-scale Inference

Deep learning techniques have shown great potential in medical image processing, particularly through accurate and reliable image segmentation on magnetic resonance imaging (MRI) scans or computed tomography (CT) scans, which allow the localization and diagnosis of lesions. However, training these segmentation models requires a large number of manually annotated pixel-level labels, which are time-consuming and labor-intensive, in contrast to image-level labels that are easier to obtain. It is imperative to resolve this problem through weakly-supervised semantic segmentation models using image-level labels as supervision since it can significantly reduce human annotation efforts. Most of the advanced solutions exploit class activation mapping (CAM). However, the original CAMs rarely capture the precise boundaries of lesions. In this study, we propose the strategy of multi-scale inference to refine CAMs by reducing the detail loss in single-scale reasoning. For segmentation, we develop a novel model named Mixed-UNet, which has two parallel branches in the decoding phase. The results can be obtained after fusing the extracted features from two branches. We evaluate the designed Mixed-UNet against several prevalent deep learning-based segmentation approaches on our dataset collected from the local hospital and public datasets. The validation results demonstrate that our model surpasses available methods under the same supervision level in the segmentation of various lesions from brain imaging.

eess.IV↗

arXiv2022

RCMNet: A deep learning model assists CAR-T therapy for leukemia

Acute leukemia is a type of blood cancer with a high mortality rate. Current therapeutic methods include bone marrow transplantation, supportive therapy, and chemotherapy. Although a satisfactory remission of the disease can be achieved, the risk of recurrence is still high. Therefore, novel treatments are demanding. Chimeric antigen receptor-T (CAR-T) therapy has emerged as a promising approach to treat and cure acute leukemia. To harness the therapeutic potential of CAR-T cell therapy for blood diseases, reliable cell morphological identification is crucial. Nevertheless, the identification of CAR-T cells is a big challenge posed by their phenotypic similarity with other blood cells. To address this substantial clinical challenge, herein we first construct a CAR-T dataset with 500 original microscopy images after staining. Following that, we create a novel integrated model called RCMNet (ResNet18 with CBAM and MHSA) that combines the convolutional neural network (CNN) and Transformer. The model shows 99.63% top-1 accuracy on the public dataset. Compared with previous reports, our model obtains satisfactory results for image classification. Although testing on the CAR-T cells dataset, a decent performance is observed, which is attributed to the limited size of the dataset. Transfer learning is adapted for RCMNet and a maximum of 83.36% accuracy has been achieved, which is higher than other SOTA models. The study evaluates the effectiveness of RCMNet on a big public dataset and translates it to a clinical dataset for diagnostic applications.

eess.IV↗

arXiv2022

Video Demoireing with Relation-Based Temporal Consistency

Moire patterns, appearing as color distortions, severely degrade image and video qualities when filming a screen with digital cameras. Considering the increasing demands for capturing videos, we study how to remove such undesirable moire patterns in videos, namely video demoireing. To this end, we introduce the first hand-held video demoireing dataset with a dedicated data collection pipeline to ensure spatial and temporal alignments of captured data. Further, a baseline video demoireing model with implicit feature space alignment and selective feature aggregation is developed to leverage complementary information from nearby frames to improve frame-level video demoireing. More importantly, we propose a relation-based temporal consistency loss to encourage the model to learn temporal consistency priors directly from ground-truth reference videos, which facilitates producing temporally consistent predictions and effectively maintains frame-level qualities. Extensive experiments manifest the superiority of our model. Code is available at \url{https://daipengwa.github.io/VDmoire_ProjectPage/}.

cs.CV↗

arXiv2022

Abandoning the Bayer-Filter to See in the Dark

Low-light image enhancement - a pervasive but challenging problem, plays a central role in enhancing the visibility of an image captured in a poor illumination environment. Due to the fact that not all photons can pass the Bayer-Filter on the sensor of the color camera, in this work, we first present a De-Bayer-Filter simulator based on deep neural networks to generate a monochrome raw image from the colored raw image. Next, a fully convolutional network is proposed to achieve the low-light image enhancement by fusing colored raw data with synthesized monochrome raw data. Channel-wise attention is also introduced to the fusion process to establish a complementary interaction between features from colored and monochrome raw images. To train the convolutional networks, we propose a dataset with monochrome and color raw pairs named Mono-Colored Raw paired dataset (MCR) collected by using a monochrome camera without Bayer-Filter and a color camera with Bayer-Filter. The proposed pipeline take advantages of the fusion of the virtual monochrome and the color raw images and our extensive experiments indicate that significant improvement can be achieved by leveraging raw sensor data and data-driven learning.

eess.IV↗

arXiv2021

Towards High-Quality Temporal Action Detection with Sparse Proposals

Temporal Action Detection (TAD) is an essential and challenging topic in video understanding, aiming to localize the temporal segments containing human action instances and predict the action categories. The previous works greatly rely upon dense candidates either by designing varying anchors or enumerating all the combinations of boundaries on video sequences; therefore, they are related to complicated pipelines and sensitive hand-crafted designs. Recently, with the resurgence of Transformer, query-based methods have tended to become the rising solutions for their simplicity and flexibility. However, there still exists a performance gap between query-based methods and well-established methods. In this paper, we identify the main challenge lies in the large variants of action duration and the ambiguous boundaries for short action instances; nevertheless, quadratic-computational global attention prevents query-based methods to build multi-scale feature maps. Towards high-quality temporal action detection, we introduce Sparse Proposals to interact with the hierarchical features. In our method, named SP-TAD, each proposal attends to a local segment feature in the temporal feature pyramid. The local interaction enables utilization of high-resolution features to preserve action instances details. Extensive experiments demonstrate the effectiveness of our method, especially under high tIoU thresholds. E.g., we achieve the state-of-the-art performance on THUMOS14 (45.7% on mAP@0.6, 33.4% on mAP@0.7 and 53.5% on mAP@Avg) and competitive results on ActivityNet-1.3 (32.99% on mAP@Avg). Code will be made available at https://github.com/wjn922/SP-TAD.

cs.CV↗

arXiv2020

A Benchmark for Multi-UAV Task Assignment of an Extended Team Orienteering Problem

A benchmark for multi-UAV task assignment is presented in order to evaluate different algorithms. An extended Team Orienteering Problem is modeled for a kind of multi-UAV task assignment problem. Three intelligent algorithms, i.e., Genetic Algorithm, Ant Colony Optimization and Particle Swarm Optimization are implemented to solve the problem. A series of experiments with different settings are conducted to evaluate three algorithms. The modeled problem and the evaluation results constitute a benchmark, which can be used to evaluate other algorithms used for multi-UAV task assignment problems.

cs.AI↗

arXiv2019

End-to-End Denoising of Dark Burst Images Using Recurrent Fully Convolutional Networks

When taking photos in dim-light environments, due to the small amount of light entering, the shot images are usually extremely dark, with a great deal of noise, and the color cannot reflect real-world color. Under this condition, the traditional methods used for single image denoising have always failed to be effective. One common idea is to take multiple frames of the same scene to enhance the signal-to-noise ratio. This paper proposes a recurrent fully convolutional network (RFCN) to process burst photos taken under extremely low-light conditions, and to obtain denoised images with improved brightness. Our model maps raw burst images directly to sRGB outputs, either to produce a best image or to generate a multi-frame denoised image sequence. This process has proven to be capable of accomplishing the low-level task of denoising, as well as the high-level task of color correction and enhancement, all of which is end-to-end processing through our network. Our method has achieved better results than state-of-the-art methods. In addition, we have applied the model trained by one type of camera without fine-tuning on photos captured by different cameras and have obtained similar end-to-end enhancements.

cs.CV↗

arXiv2015

Integral Control Feedback Circuit for the Reactivation of Malfunctioning p53 Pathway

We developed a strategy to control p53 levels when the p53 concentration falls below a desired threshold . Based on an established p53-MDM2 mathematical model that also incorporates microRNA regulators (p53-MDM2-miRNA), we applied a control action in closed-loop with respect to this model. In particular, we employ various architectures of synthetic circuit with integral feedback control, illustrating varying degree in adaptive response to step-wise perturbation of p53.

q-bio.MN↗