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Larry DeWerd

Publications and source records attributed to Larry DeWerd.

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Evaluation of the Exradin A30 Parallel Plate Ion Chamber as a Reference Dosimeter in Ultra-High Dose Rate (UHDR) Electron Beams

Reliable reference dosimetry for ultra-high dose-rate (UHDR) beams (>40 Gy/s) is challenging because conventional ionization chambers (ICs) exhibit saturation from ion recombination. The Exradin A30 IC uses an ultra-thin 0.3-mm electrode spacing to improve charge-collection efficiency (CCE). This study evaluated the commercial A30 as a reference dosimeter for UHDR electron beams by characterizing leakage current, CCE, polarity correction (Ppol), and beam-quality correction factors (kQ). Measurements were performed with a 9-MeV IntraOp Mobetron from the accelerator head, achieving up to 9 Gy per pulse (DPP) and an instantaneous dose rate of 2.25 MGy/s. Data were acquired in grounded water-equivalent plastic, distilled water, and saline water. DPP was varied by changing SSD at a fixed 4-{\mu}s pulse width, while pulse repetition frequency (PRF) ranged from 5 to 90 Hz. CCE was determined using EBT-XD film under matched UHDR and conventional dose and energy conditions. CCE and Ppol were also evaluated as functions of DPP and PRF in distilled and saline water. Values of kQ were calculated using Monte Carlo simulations and measured in TrueBeam electron beams. Leakage current was <2 fA. Both CCE and Ppol decreased with increasing DPP; however, CCE remained 90-99% across all three phantoms, while Ppol decreased from 0.990 to 0.981 in liquid and solid water. Neither CCE nor Ppol depended on PRF over 5-90 Hz. Measured and calculated kQ values agreed within 0.8% at all energies except 9 MeV, where they differed by 2%. The A30 exhibited 5% recombination at DPP up to 5 Gy in distilled and saline water. Its response in solid phantoms was affected by charge buildup, which was mitigated by grounding. With appropriate CCE corrections and grounded solid phantoms, the commercial A30 is suitable for reference dosimetry in UHDR electron beams.

physics.med-ph

Development of novel ionization chambers for reference dosimetry in electron FLASH radiotherapy

The aim of this study was to optimize the design and performance of parallel plate ion chambers for use in ultra-high dose rate (UHDR) dosimetry applications, and evaluate their potential as reference class chambers for calibration purposes. Three chambers were designed and produced: the A11-VAR (0.2-1.0 mm electrode gap, 20 mm diameter collector), the A11-TPP (0.3 mm electrode gap, 20 mm diameter collector), and the A30 (0.3 mm electrode gap, 5.4 mm diameter collector).The chambers underwent full characterization using an UHDR 9 MeV electron beam with individually varied beam parameters of pulse repetition frequency (PRF, 10-120Hz), pulse width (PW, 0.5-4us), and pulse amplitude (0.01-9 Gy/pulse). The response of the ion chambers was evaluated as a function of the dose per pulse (DPP), PRF, PW, dose rate, electric field strength, and electrode gap. The chamber response was found to be dependent on DPP and PW, whose dependencies were mitigated with larger electric field strengths and smaller electrode spacing. At a constant electric field strength, we measured a larger charge collection efficiency (CCE) as a function of DPP for ion chambers with a smaller electrode gap in the A11-VAR. For ion chambers with identical electrode gap (A11-TPP and A30), higher electric field strengths were found to yield better CCE at higher DPP. A PW dependence was observed at low electric field strengths (500 V/mm) for DPP values ranging from 1-5 Gy at PWs ranging from 0.5-4 {\mu}s, but at electric field strengths of 1000 V/mm and higher, these effects become negligible. This study confirmed that the charge collection efficiency of ion chambers depends strongly on the electrode spacing and the electric field strength, and also on the DPP and the PW of the UHDR beam. The new finding of this study is that the PW dependence becomes negligible with reduced electrode spacing and increased electric field.

physics.med-ph