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Laura A. Cobus

Publications and source records attributed to Laura A. Cobus.

6 recordsLinked to original sources

Ultrasound Matrix Imaging-Part II: The distortion matrix for aberration correction over multiple isoplanatic patches

This is the second article in a series of two which report on a matrix approach for ultrasound imaging in heterogeneous media. This article describes the quantification and correction of aberration, i.e. the distortion of an image caused by spatial variations in the medium speed-of-sound. Adaptive focusing can compensate for aberration, but is only effective over a restricted area called the isoplanatic patch. Here, we use an experimentally-recorded matrix of reflected acoustic signals tosynthesize a set of virtual transducers. We then examine wave propagation between these virtual transducers and an arbitrary correction plane. Such wave-fronts consist of two components: (i) An ideal geometric wave-front linked to diffraction and the input focusing point, and; (ii) Phase distortions induced by the speed-of-sound variations. These distortions are stored in a so-called distortion matrix, the singular value decomposition of which gives access to an optimized focusing law at any point. We show that, by decoupling the aberrations undergone by the outgoing and incoming waves and applying an iterative strategy, compensation for even high-order and spatially-distributed aberrations can be achieved. After a numerical validation of the process, ultrasound matrix imaging (UMI) is applied to the in-vivo imaging of a gallbladder. A map of isoplanatic modes is retrieved and is shown to be strongly correlated with the arrangement of tissues constituting the medium. The corresponding focusing laws yield an ultrasound image with drastically improved contrast and transverse resolution. UMI thus provides a flexible and powerful route towards computational ultrasound.

eess.IV

Ultrasound Matrix Imaging-Part I: The focused reflection matrix, the F-factor and the role of multiple scattering

This is the first article in a series of two dealing with a matrix approach for aberration quantification and correction in ultrasound imaging. Advanced synthetic beamforming relies on a double focusing operation at transmission and reception on each point of the medium. Ultrasound matrix imaging (UMI) consists in decoupling the location of these transmitted and received focal spots. The response between those virtual transducers form the so-called focused reflection matrix that actually contains much more information than a confocal ultrasound image. In this paper, a time-frequency analysis of this matrix is performed, which highlights the single and multiple scattering contributions as well as the impact of aberrations in the monochromatic and broadband regimes. Interestingly, this analysis enables the measurement of the incoherent input-output point spread function at any pixel of this image. A fitting process enables the quantification of the single scattering, multiple scattering and noise components in the image. From the single scattering contribution, a focusing criterion is defined, and its evolution used to quantify the amount of aberration throughout the ultrasound image. In contrast to the state-of-the-art coherence factor, this new indicator is robust to multiple scattering and electronic noise, thereby providing a contrasted map of the focusing quality at a much better transverse resolution. After a validation of the proof-of-concept based on time-domain simulations, UMI is applied to the in-vivo study of a human calf. Beyond this specific example, UMI opens a new route for speed-of-sound and scattering quantification in ultrasound imaging.

physics.app-ph

Crossover from renormalized to conventional diffusion near the 3D Anderson localization transition for light

We report on anomalous light transport in the strong scattering regime. Using low-coherence interferometry, we measure the reflection matrix of titanium dioxide powders, revealing crucial features of strong optical scattering which can not be observed with transmission measurements: (i) a subdiffusive regime of transport at early times of flight that is a direct consequence of predominant recurrent scattering loops, and (ii) a crossover to a conventional, but extremely slow, diffusive regime at long times. These observations support previous predictions that near-field coupling between scatterers prohibits Anderson localization of light in three-dimensional disordered media.

cond-mat.dis-nn

Distortion matrix approach for ultrasound imaging of random scattering media

Focusing waves inside inhomogeneous media is a fundamental problem for imaging. Spatial variations of wave velocity can strongly distort propagating wavefronts and degrade image quality. Adaptive focusing can compensate for such aberration, but is only effective over a restricted field of view. Here, we introduce a full-field approach to wave imaging based on the concept of the distortion matrix. This operator essentially connects any focal point inside the medium with the distortion that a wavefront, emitted from that point, experiences due to heterogeneities. A time-reversal analysis of the distortion matrix enables the estimation of the transmission matrix that links each sensor and image voxel. Phase aberrations can then be unscrambled for any point, providing a full-field image of the medium with diffraction-limited resolution. Importantly, this process is particularly efficient in random scattering media, where traditional approaches such as adaptive focusing fail. Here, we first present an experimental proof-of-concept on a tissue mimicking phantom, and then apply the method to in vivo imaging of human soft tissues. While introduced here in the context of acoustics, this approach can also be extended to optical microscopy, radar or seismic imaging.

eess.IV

Reflection matrix approach for quantitative imaging of scattering media

We present a physically intuitive matrix approach for wave imaging and characterization in scattering media. The experimental proof-of-concept is performed with ultrasonic waves, but this approach can be applied to any field of wave physics for which multi-element technology is available. The concept is that focused beamforming enables the synthesis, in transmit and receive, of an array of virtual transducers which map the entire medium to be imaged. The inter-element responses of this virtual array form a focused reflection matrix from which spatial maps of various characteristics of the propagating wave can be retrieved. Here we demonstrate: (i) a local focusing criterion that enables the image quality and the wave velocity to be evaluated everywhere inside the medium, including in random speckle, and (ii) an highly resolved spatial mapping of the prevalence of multiple scattering, which constitutes a new and unique contrast for ultrasonic imaging. The approach is demonstrated for a controllable phantom system, and for in vivo imaging of the human abdomen. More generally, this matrix approach opens an original and powerful route for quantitative imaging in wave physics.

physics.app-ph

Recurrent scattering and memory effect at the Anderson localization transition

We report on ultrasonic measurements of the propagation operator in a strongly scattering mesoglass. The backscattered field is shown to display a deterministic spatial coherence due to a remarkably large memory effect induced by long recurrent trajectories. Investigation of the recurrent scattering contribution directly yields the probability for a wave to come back close to its starting spot. The decay of this quantity with time is shown to change dramatically near the Anderson localization transition. The singular value decomposition of the propagation operator reveals the dominance of very intense recurrent scattering paths near the mobility edge.

cond-mat.dis-nn