arXiv subjects

Laura F. White

Publications and source records attributed to Laura F. White.

2 recordsLinked to original sources

arXiv2026

Network Epidemic Control via Model Predictive Control: Extended Version

Balancing the societal costs of non-pharmaceutical interventions with epidemic suppression requires adaptive feedback control. Rather than relying on state-dependent operational caps, we formulate an infinite-horizon optimal control problem for a networked SIQR model that strictly enforces suppression via a hard spectral constraint on the transmission dynamics. We derive a safety-critical Model Predictive Control (MPC) approximation that embeds this spectral certificate stage-wise, yielding a tunable exponential decay rate. Furthermore, we construct a terminal set ensuring recursive feasibility and a feasible continuation that decays globally, proving positive invariance directly via the physical depletion of susceptibles rather than standard quadratic Lyapunov functions. To handle prediction uncertainty, we develop a robust counterpart that replaces nominal constraints by upper-envelope versions, recovering recursive feasibility and finite-horizon realized decay. We conclude by validating our approaches using simulation studies that leverage public data from counties in the state of Massachusetts.

math.OC↗

arXiv2024

Network-Based Epidemic Control Through Optimal Travel and Quarantine Management

Motivated by the swift global transmission of infectious diseases, we present a comprehensive framework for network-based epidemic control. Our aim is to curb epidemics using two different approaches. In the first approach, we introduce an optimization strategy that optimally reduces travel rates. We analyze the convergence of this strategy and show that it hinges on the network structure to minimize infection spread. In the second approach, we expand the classic SIR model by incorporating and optimizing quarantined states to strategically contain the epidemic. We show that this problem reduces to the problem of matrix balancing. We establish a link between optimization constraints and the epidemic's reproduction number, highlighting the relationship between network structure and disease dynamics. We demonstrate that applying augmented primal-dual gradient dynamics to the optimal quarantine problem ensures exponential convergence to the KKT point. We conclude by validating our approaches using simulation studies that leverage public data from counties in the state of Massachusetts.

eess.SY↗