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Lauren Hong

Publications and source records attributed to Lauren Hong.

5 recordsLinked to original sources

Watermark under Fire: A Robustness Evaluation of LLM Watermarking

Various watermarking methods (``watermarkers'') have been proposed to identify LLM-generated texts; yet, due to the lack of unified evaluation platforms, many critical questions remain under-explored: i) What are the strengths/limitations of various watermarkers, especially their attack robustness? ii) How do various design choices impact their robustness? iii) How to optimally operate watermarkers in adversarial environments? To fill this gap, we systematize existing LLM watermarkers and watermark removal attacks, mapping out their design spaces. We then develop WaterPark, a unified platform that integrates 10 state-of-the-art watermarkers and 12 representative attacks. More importantly, by leveraging WaterPark, we conduct a comprehensive assessment of existing watermarkers, unveiling the impact of various design choices on their attack robustness. We further explore the best practices to operate watermarkers in adversarial environments. We believe our study sheds light on current LLM watermarking techniques while WaterPark serves as a valuable testbed to facilitate future research.

cs.CR

PepMLM: Target Sequence-Conditioned Generation of Therapeutic Peptide Binders via Span Masked Language Modeling

Target proteins that lack accessible binding pockets and conformational stability have posed increasing challenges for drug development. Induced proximity strategies, such as PROTACs and molecular glues, have thus gained attention as pharmacological alternatives, but still require small molecule docking at binding pockets for targeted protein degradation. The computational design of protein-based binders presents unique opportunities to access "undruggable" targets, but have often relied on stable 3D structures or structure-influenced latent spaces for effective binder generation. In this work, we introduce PepMLM, a target sequence-conditioned generator of de novo linear peptide binders. By employing a novel span masking strategy that uniquely positions cognate peptide sequences at the C-terminus of target protein sequences, PepMLM fine-tunes the state-of-the-art ESM-2 pLM to fully reconstruct the binder region, achieving low perplexities matching or improving upon validated peptide-protein sequence pairs. After successful in silico benchmarking with AlphaFold-Multimer, outperforming RFDiffusion on structured targets, we experimentally verify PepMLM's efficacy via fusion of model-derived peptides to E3 ubiquitin ligase domains, demonstrating endogenous degradation of emergent viral phosphoproteins and Huntington's disease-driving proteins. In total, PepMLM enables the generative design of candidate binders to any target protein, without the requirement of target structure, empowering downstream therapeutic applications.

q-bio.BM

PETA: Parameter-Efficient Trojan Attacks

Parameter-efficient fine-tuning (PEFT) enables efficient adaptation of pre-trained language models (PLMs) to specific tasks. By tuning only a minimal set of (extra) parameters, PEFT achieves performance that is comparable to standard fine-tuning. However, despite its prevalent use, the security implications of PEFT remain largely unexplored. In this paper, we take the initial steps and present PETA, a novel trojan attack that compromises the weights of PLMs by accounting for downstream adaptation through bilevel optimization: the upper-level objective embeds the backdoor into a model while the lower-level objective simulates PEFT to both retain the PLM's task-specific performance and ensure that the backdoor persists after fine-tuning. With extensive evaluation across a variety of downstream tasks and trigger designs, we demonstrate PETA's effectiveness in terms of both attack success rate and clean accuracy, even when the attacker does not have full knowledge of the victim user's training process.

cs.CL

ToolLLM: Facilitating Large Language Models to Master 16000+ Real-world APIs

Despite the advancements of open-source large language models (LLMs), e.g., LLaMA, they remain significantly limited in tool-use capabilities, i.e., using external tools (APIs) to fulfill human instructions. The reason is that current instruction tuning largely focuses on basic language tasks but ignores the tool-use domain. This is in contrast to the excellent tool-use capabilities of state-of-the-art (SOTA) closed-source LLMs, e.g., ChatGPT. To bridge this gap, we introduce ToolLLM, a general tool-use framework encompassing data construction, model training, and evaluation. We first present ToolBench, an instruction-tuning dataset for tool use, which is constructed automatically using ChatGPT. Specifically, the construction can be divided into three stages: (i) API collection: we collect 16,464 real-world RESTful APIs spanning 49 categories from RapidAPI Hub; (ii) instruction generation: we prompt ChatGPT to generate diverse instructions involving these APIs, covering both single-tool and multi-tool scenarios; (iii) solution path annotation: we use ChatGPT to search for a valid solution path (chain of API calls) for each instruction. To enhance the reasoning capabilities of LLMs, we develop a novel depth-first search-based decision tree algorithm. It enables LLMs to evaluate multiple reasoning traces and expand the search space. Moreover, to evaluate the tool-use capabilities of LLMs, we develop an automatic evaluator: ToolEval. Based on ToolBench, we fine-tune LLaMA to obtain an LLM ToolLLaMA, and equip it with a neural API retriever to recommend appropriate APIs for each instruction. Experiments show that ToolLLaMA demonstrates a remarkable ability to execute complex instructions and generalize to unseen APIs, and exhibits comparable performance to ChatGPT. Our ToolLLaMA also demonstrates strong zero-shot generalization ability in an out-of-distribution tool-use dataset: APIBench.

cs.AI

Monitoring and Adapting ML Models on Mobile Devices

ML models are increasingly being pushed to mobile devices, for low-latency inference and offline operation. However, once the models are deployed, it is hard for ML operators to track their accuracy, which can degrade unpredictably (e.g., due to data drift). We design the first end-to-end system for continuously monitoring and adapting models on mobile devices without requiring feedback from users. Our key observation is that often model degradation is due to a specific root cause, which may affect a large group of devices. Therefore, once the system detects a consistent degradation across a large number of devices, it employs a root cause analysis to determine the origin of the problem and applies a cause-specific adaptation. We evaluate the system on two computer vision datasets, and show it consistently boosts accuracy compared to existing approaches. On a dataset containing photos collected from driving cars, our system improves the accuracy on average by 15%.

cs.LG