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Lei Du

Publications and source records attributed to Lei Du.

At least 19 recordsLinked to original sources

Optomechanical systems with a Fano membrane in the middle

Conventional membrane-in-the-middle (MIM) optomechanical systems offer limited control over the optical linewidth, which can limit their performance when operating in the unresolved-sideband regime. We investigate cavity optomechanics with a photonic-crystal Fano membrane placed at the center of a Fabry-P\'erot (FP) cavity. In contrast to a conventional dielectric membrane, the photonic-crystal membrane supports a localized optical resonance, which hybridizes with the cavity field and enables spectral engineering of the relevant optical modes. Besides the usual dispersive optomechanical coupling associated with cavity-length changes, the membrane motion also modifies the Fano-mode resonance and its hybridization with the cavity field. We consider two limits set by the membrane reflectivity: a transparent-membrane regime with a single FP-like mode, and a reflective-membrane regime with two coupled subcavity modes. In the latter case, only the symmetric cavity mode hybridizes with the Fano mode, while the antisymmetric mode remains decoupled. Using quantum Langevin equations together with a transfer-matrix description of the optical scattering problem, we show that the Fano-induced hybridization can generate narrow optical normal modes that remain efficiently accessible to the external drive for experimentally realistic parameters. These modes can provide effective sideband resolution and enable ground-state cooling of the membrane motion even when the bare cavity is in the unresolved-sideband regime. Our results establish Fano MIM systems as a promising platform for spectral and optomechanical engineering.

physics.optics

Charging Quantum Batteries with Chiral Squeezing

We propose a quantum-battery charger based on a driven bosonic Kitaev chain (BKC), where chiral squeezing converts passive input fluctuations into ordered, non-passive battery states. While a coherent input pulse exhibits phase-sensitive chiral transport, the charging dynamics is dominated by bidirectionally propagating fluctuations that are amplified and squeezed into orthogonal quadratures at opposite chain ends. In contrast to conventional phase-preserving amplifiers, our scheme stores largely extractable energy and achieves a work-like signal-to-noise ratio (SNR) near unity, even in the presence of thermal noise and moderate symmetry-preserving disorder.

quant-ph

Mode-realigned pointwise interpolation (MRPWI) for efficient POD-Galerkin parametric reduced-order models

As a cornerstone of reduced-order modeling, the POD-Galerkin framework has garnered widespread attention and remains one of the most widely adopted approaches. Constructing POD-Galerkin PROMs involves integrating this framework with advanced interpolation techniques to obtain POD modes at target (unseen) parameters. While Grassmann manifold interpolation (GMI) serves as an accurate baseline, mode-realigned pointwise interpolation (MRPWI) is proposed to develop highly efficient PROMs that maintain comparable accuracy. Notably, the MRPWI employs a two-step mode realignment procedure, consisting of sign alignment and rotation alignment, to effectively synchronize the POD modes. Demonstration and evaluation of the constructed POD-Galerkin PROMs are conducted by examining flow over a cylinder. These models exhibit high fidelity in comparison to direct numerical simulation and standard POD-Galerkin ROMs. PROMs constructed via MRPWI achieve accuracy comparable to those using GMI, while providing significantly higher computational efficiency.

math.NA

Efficient Solution of Generalized Sylvester Equations via Preconditioned Alternating Anderson Acceleration

This paper considers the numerical solution of generalized Sylvester matrix equations, which arise in many scientific and engineering applications but remain challenging to solve efficiently, particularly when the coefficient matrices are general and the spectral radius of the associated operator is large but not greater than $1$. We propose a new iterative method, termed preconditioned-alternating Anderson acceleration (P-aAA), which combines a matrix-oriented variant of Anderson acceleration (AA) with a novel preconditioning strategy. The method alternates between preconditioned fixed-point iterations and Anderson acceleration updates, thereby reducing both computational cost and iteration count. A key contribution is the development of an efficient preconditioning operator based on a first-order Neumann series approximation, which avoids expensive operator inversions while enhancing convergence. We theoretically prove that the proposed preconditioning operator accelerates the convergence rate without increasing the overall computational complexity. Extensive numerical experiments further demonstrate that the proposed approach consistently outperforms existing state-of-the-art methods for both medium- and large-scale problems, achieving substantial reductions in computation time and iteration number.

math.NA

Nonlinear quantum optomechanics in a Fano-mirror microcavity system

We study a Fano-mirror optomechanical system in the quantum nonlinear regime. In this system, two strongly lossy optical modes hybridize through both coherent and dissipative couplings to form an effective optical mode with a drastically reduced linewidth. This linewidth reduction enables the system to access the single-photon strong-coupling and sideband-resolved regimes simultaneously. We formulate the system dynamics using an effective master-equation approach and benchmark it against quantum Langevin and dressed-state master-equation descriptions. With experimentally realistic parameters, we predict clear quantum signatures, including photon blockade and the generation of mechanical cat states. Our work establishes the Fano-mirror architecture as a promising platform for harnessing single-photon optomechanical nonlinearities for quantum state engineering under achievable experimental conditions.

quant-ph

Quantitative cancer-immunity cycle modeling to optimize bevacizumab and atezolizumab combination therapy for advanced renal cell carcinoma

The incidence of advanced renal cell carcinoma(RCC) has been rising, presenting significant challenges due to the limited efficacy and severe side effects of traditional radiotherapy and chemotherapy. While combination immunotherapies show promise, optimizing treatment strategies remains difficult due to individual heterogeneity. To address this, we developed a Quantitative Cancer-Immunity Cycle (QCIC) model that integrates ordinary differential equations with stochastic modelling to quantitatively characterize and predict tumor evolution in patients with advanced RCC. By systematically integrating quantitative systems pharmacology principles with biological mechanistic knowledge, we constructed a virtual patient cohort and calibrated the model parameters using clinical immunohistochemistry data to ensure biological validity. To enhance predictive performance, we coupled the model with pharmacokinetic equations and defined the Tumor Response Index (TRI) as a quantitative metric of efficacy. Systematic analysis of the QCIC model allowed us to determine an optimal treatment regimen for the combination of bevacizumab and atezolizumab and identify tumor biomarkers with clinical predictive value. This study provides a theoretical framework and methodological support for precision medicine in the treatment of advanced RCC.

q-bio.QM

Exotic collective behaviors of giant quantum emitters in two-dimensional baths

Nonlocal light-matter interactions with giant atoms in high-dimensional environments are not only fundamentally intriguing for testing quantum electrodynamics beyond the dipole approximation but also crucial for building high-dimensional quantum networks and engineering multipartite entangled states. Given the enigmatic and largely uncharted collective signatures exhibited by multiple giant atoms within two-dimensional optical baths, we delve into their nonperturbative collective dynamics within the single-excitation subspace, focusing on the case where they are coupled to a common two-dimensional photonic reservoir and employing a resolvent operator approach. We demonstrate that precisely engineered atomic arrangements lead to unconventional quantum dynamics, featuring non-Markovianity-induced beats and long-lived bound states in the continuum, thereby providing a versatile platform for implementing two-dimensional quantum memory. Phenomenologically, we observe the emergence of exotic photon emission patterns in both two- and three-dimensional (3D) baths. The emission directions are shown to be precisely controllable on demand through exact phase engineering of the coupling parameters, enabling a highly efficient chiral light-matter interface. Moreover, our generalization to a 3D bath reveals that coherent dipole-dipole interactions can survive despite the coupling to a continuum of modes, a finding that challenges conventional wisdom regarding decoherence.

quant-ph

Temporal Beam Self-Cleaning in Second-Harmonic Generation

The spatial-temporal beam quality of laser sources is crucial for applications such as nonlinear spectroscopy and master oscillator power amplification systems. However, the temporal stability remains challenged by issues like line-width broadening and high-power demand in efforts to improve it. In this work, we investigate the effect of the second-harmonic generation process on the laser characteristics under three longitudinal mode regimes: single-longitudinal-mode, dual-longitudinal-mode, and multi-longitudinal-mode. The results demonstrate that the second-harmonic generation process effectively stabilizes the temporal characteristics of the laser and enhances its correlation, leading to a temporally clean output beam. The physical mechanism of the observed temporal stabilization effect can be attributed to a high-peak-pulse attenuation effect, jointly induced by nonuniform longitudinal-mode depletion and phase preservation in the residual fundamental wave. Statistical analysis indicates that at the maximum fundamental-wave power in the multi-longitudinal-mode regime, the standard deviation and peak-to-valley values derived from the normalized temporal profile decrease from 0.6122 and 5.6846 for the fundamental wave to 0.189 and 0.8847 for the residual fundamental wave. Meanwhile, the background level of the intensity auto-correlation function rises from ~0.72 to ~0.96, revealing its evolution toward a more coherent state. To the best of our knowledge, this research presents the first demonstration of laser temporal stabilization and correlation enhancement via second-harmonic generation. It not only deepens the comprehension of second-harmonic generation mechanisms, but also opens up a new avenue for realizing temporal beam self-cleaning of light.

physics.optics

Single-Period Floquet Control of Bosonic Codes with Quantum Lattice Gates

Bosonic codes constitute a promising route to fault-tolerant quantum computing. Existing Floquet protocols enable analytical construction of bosonic codes but typically rely on slow adiabatic ramps with thousands of driving periods. In this work, we circumvent this bottleneck by introducing an analytical and deterministic Floquet method that directly synthesizes arbitrary unitaries within a single period. The phase-space unitary ensembles generated by our approach reproduce the Haar-random statistics, enabling practical pseudorandom states in continuous-variable systems. We prepare various prototypical bosonic codes from vacuum and implement single-qubit logical gates with high fidelities using quantum lattice gates. By harnessing the full intrinsic nonlinearity of Josephson junctions, quantum lattice gates decompose quantum circuits into primitive operations for efficient continuous-variable quantum computing.

quant-ph

GRIDAI: Generating and Repairing Intrusion Detection Rules via Collaboration among Multiple LLM-based Agents

Rule-based network intrusion detection systems play a crucial role in the real-time detection of Web attacks. However, most existing works primarily focus on automatically generating detection rules for new attacks, often overlooking the relationships between new attacks and existing rules, which leads to significant redundancy within the ever-expanding ruleset. To address this issue, we propose GRIDAI, a novel end-to-end framework for the automated Generation and Repair of Intrusion Detection rules through collaboration among multiple LLM-based agents. Unlike traditional methods, GRIDAI first assesses the nature of incoming attack samples. If the sample represents a new attack type, it is used to generate a new rule. Otherwise, the sample is identified as a variant of an attack already covered by an existing rule and used to repair the rule by updating the corresponding signature, thereby enhancing its generalization capability. Additionally, to mitigate syntactic and semantic errors in rules caused by LLM hallucinations, we incorporate a tool-based real-time validation mechanism and a representative attack sample maintained for each rule, enabling fully automated rule generation and repair. Comprehensive experiments were conducted on a public dataset containing seven types of attacks and a private dataset with 43 attack types. The results demonstrate that GRIDAI accurately identifies the relationships between new attack samples and existing rules, efficiently generates and repairs rules to handle new attacks and variants, and effectively mitigates the impact of LLM hallucinations.

cs.CR

Selective high-order topological states and tunable chiral emission in atomic metasurfaces

Atomic metasurfaces (AMs) provide a powerful nanophotonic platform for integrating topological effects into quantum many-body systems. In this Letter, we investigate the quantum optical and topological properties of a two-dimensional Kagome AM, going beyond the tight-binding approximation and incorporating all-to-all interactions. We reveal selective higher-order topological states with a unique dynamical ``chasing" behavior, protected by a generalized chiral symmetry and enabling efficient topological directional transfer. By introducing an impurity atom -- a giant atom -- coupled to all array atoms, we observe chiral emission patterns strongly dependent on the atomic polarization. This nonlocal coupling structure allows exploration of self-interference effects at subwavelength scales. Our findings establish AMs as a versatile platform for engineering tunable topological states and chiral quantum optical phenomena, with potential applications in customized light sources and photonic devices.

quant-ph

Comprehensively stratifying MCIs into distinct risk subtypes based on brain imaging genetics fusion learning

Mild cognitive impairment (MCI) is the prodromal stage of Alzheimer's disease (AD) and thus enrolling MCI subjects to undergo clinical trials is worthwhile. However, MCI groups usually show significant diversity and heterogeneity in the pathology and symptom, which pose great challenge to accurately select appropriate subjects. This study aimed to stratify MCI subjects into distinct subgroups with substantial difference in the risk of transitioning to AD by fusing multimodal brain imaging genetic data. The integrated imaging genetics method comprised three modules, i.e., the whole-genome-oriented risk genetic information extraction module (RGE), the genetic-to-brain mapping module (RG2PG), and the genetic-guided pseudo-brain fusion module (CMPF). We used data from AD Neuroimaging Initiative (ADNI) and identified two MCI subtypes, called low-risk MCI (lsMCI) and high-risk MCI (hsMCI). We also validated that the two subgroups showed distinct patterns of in terms of multiple biomarkers including genetics, demographics, fluid biomarkers, brain imaging features, clinical symptoms and cognitive functioning at baseline, as well as their longitudinal developmental trajectories. Furthermore, we also identified potential biomarkers that may implicate the risk of MCIs, providing critical insights for patient stratification at early stage.

q-bio.QM

Remote entanglement generation via enhanced quantum state transfer

Achieving robust and scalable remote quantum entanglement is a fundamental challenge for the development of distributed quantum networks and modular quantum computing systems. Along this, perfect state transfer (PST) and fractional state transfer (FST) have emerged as promising schemes for quantum state transfer and remote entanglement generation using only nearest-neighbor couplings. However, the current implementations suffer from quantum loss and limited parameter tunability. In this work, we propose a new quantum state transfer scheme based on a zig-zag configuration, which introduces a controlling parameter for PST and FST. We show that this new parameter can suppress the population in the intermediate qubits, thereby reducing losses. We experimentally demonstrate the dynamics of different configurations on a superconducting quantum processor, achieving an $18\%$ reduction in error for remote Bell state generation in a 1D ($1\times5$) qubit chain, and exhibit robustness against certain types of noise. Then we extend our approach to a 2D network, successfully generating a W state among the four corner qubits. These results highlight the potential of our enhanced quantum state transfer scheme for scalable and noise-resilient quantum communication and computing.

quant-ph

Experimental robustness benchmarking of quantum neural networks on a superconducting quantum processor

Quantum machine learning (QML) models, like their classical counterparts, are vulnerable to adversarial attacks, hindering their secure deployment. Here, we report the first systematic experimental robustness benchmark for 20-qubit quantum neural network (QNN) classifiers executed on a superconducting processor. Our benchmarking framework features an efficient adversarial attack algorithm designed for QNNs, enabling quantitative characterization of adversarial robustness and robustness bounds. From our analysis, we verify that adversarial training reduces sensitivity to targeted perturbations by regularizing input gradients, significantly enhancing QNN's robustness. Additionally, our analysis reveals that QNNs exhibit superior adversarial robustness compared to classical neural networks, an advantage attributed to inherent quantum noise. Furthermore, the empirical upper bound extracted from our attack experiments shows a minimal deviation ($3 \times 10^{-3}$) from the theoretical lower bound, providing strong experimental confirmation of the attack's effectiveness and the tightness of fidelity-based robustness bounds. This work establishes a critical experimental framework for assessing and improving quantum adversarial robustness, paving the way for secure and reliable QML applications.

quant-ph

Demonstrating Coherent Quantum Routers for Bucket-Brigade Quantum Random Access Memory on a Superconducting Processor

Quantum routers (QRouters) are essential components of bucket-brigade quantum random access memory (QRAM), enabling quantum applications such as Grover's search and quantum machine learning. Despite significant theoretical advances, achieving scalable and coherent QRouters experimentally remains challenging. Here, we demonstrate coherent quantum routers using a superconducting quantum processor, laying a practical foundation for scalable QRAM systems. The quantum router at the core of our implementation utilizes the transition composite gate (TCG) scheme, wherein auxiliary energy levels temporarily mediate conditional interactions, substantially reducing circuit depth compared to traditional gate decompositions. Moreover, by encoding routing addresses in the non-adjacent qutrit states $|0\rangle$ and $|2\rangle$, our design inherently enables eraser-detection capability, providing efficient post-selection to mitigate routing errors. Experimentally, we achieve individual QRouter fidelities up to 95.74%, and validate scalability through a two-layer quantum routing network achieving an average fidelity of 82.40%. Our results represent a significant advancement in quantum routing technology, providing enhanced fidelity, built-in error resilience, and practical scalability crucial for the development of future QRAM and large-scale quantum computing architectures.

quant-ph

Dressed Interference in Giant Superatoms: Entanglement Generation and Transfer

We introduce the concept of giant superatoms (GSAs), where two or more interacting atoms are nonlocally coupled to a waveguide through one of them, and explore their unconventional quantum dynamics. For braided GSAs, this setup enables decoherence-free transfer and swapping of their internal entangled states. For separate GSAs, engineering coupling phases leads to state-dependent chiral emission, which enables selective, directional quantum information transfer. This mechanism further facilitates remote generation of W-class entangled states. Our results thereby open exciting possibilities for quantum networks and quantum information processing.

quant-ph

Engineering Bosonic Codes with Quantum Lattice Gates

Bosonic codes offer a hardware-efficient approach to encoding and protecting quantum information with a single continuous-variable bosonic system. In this paper, we introduce a new universal quantum gate set composed of only one type of gate element, which we call the quantum lattice gate, to engineer bosonic code states for fault-tolerant quantum computing. We develop a systematic framework for code state engineering based on the Floquet Hamiltonian engineering, where the target Hamiltonian is constructed directly from the given target state(s). We apply our method to three basic code state engineering processes, including single code state preparation, code space embedding and code space transformation. We explore the application of our method to automatic quantum error correction against single-photon loss with four-legged cat codes. Our proposal is particularly well-suited for superconducting circuit architectures with Josephson junctions, where the full nonlinearity of Josephson junction potential is harnessed as a quantum resource and the quantum lattice gate can be implemented on a sub-nanosecond timescale.

quant-ph

Unconventional and robust light-matter interactions based on the non-Hermitian skin effect

Lattice models featuring the non-Hermitian skin effect have attracted rapidly growing interest due to their nontrivial spectral topology and the exotic field dynamics they enable. Such non-Hermitian lattices provide a promising paradigm for engineering exotic light-matter interactions which benefit from the intrinsic chirality and unconventional (non-Bloch) band theory. Here we study a series of unconventional light-matter interactions between quantum emitters and the prototypical Hatano--Nelson model, and briefly discuss the case with an extended lattice model dubbed the bosonic Kitaev chain. We focus on the robustness of the dynamics against various imperfections and elucidate the underlying mechanisms. We consider both small emitters, which interact with the lattice at single sites, and giant emitters coupling at multiple sites. The latter exhibit an exclusive amplification mechanism, which we find enables decoherence-free dynamics even in the presence of extra dissipation in the system. The protection from dissipation arises from the cooperation of the non-Hermiticity and the self-interference effect, and is therefore lacking for small emitters. These results not only provide deeper insights into the interplay of non-Hermiticity and various interference effects, but also have potential applications in engineering exotic spin Hamiltonians and quantum networks.

quant-ph