Lena D. Swamikannan | Searcharxiv

arXiv2026

A Federated Learning Framework for Privacy-Preserving Oral Cancer Screening on Smartphones

Data are the cornerstone of robust AI models. However, in the medical domain, access to reliable data is constrained by regulatory requirements and patient privacy, and clinical oral images are particularly difficult to obtain. Federated learning (FL) mitigates these constraints by enabling collaborative model development across decentralized datasets without centralizing or sharing patient data. This work presents a practical FL framework that supports geographically distributed collaboration among AI healthcare researchers and facilitates the development of robust models for oral cancer screening. Client devices were interconnected via Tailscale to provide secure networking and real-time communication. We implemented the FL workflow using the Flower framework for server-side aggregation, while client deployment and orchestration were configured manually; no enterprise FL platforms were used. To support a smartphone-based screening application, we evaluated lightweight, mobile-friendly architectures including MobileNetV2, MobileNetV3Large, and MobileNetV4-Conv-Small (MNv4-Conv-S). Across the global lightweight models aggregated using FedAvg, the MNv4-Conv-S based global model (GM-V4) achieved the best performance, reaching an AUC of 0.929 and an accuracy of 87%

cs.CR↗

arXiv2025

Robust Classification of Oral Cancer with Limited Training Data

Oral cancer ranks among the most prevalent cancers globally, with a particularly high mortality rate in regions lacking adequate healthcare access. Early diagnosis is crucial for reducing mortality; however, challenges persist due to limited oral health programs, inadequate infrastructure, and a shortage of healthcare practitioners. Conventional deep learning models, while promising, often rely on point estimates, leading to overconfidence and reduced reliability. Critically, these models require large datasets to mitigate overfitting and ensure generalizability, an unrealistic demand in settings with limited training data. To address these issues, we propose a hybrid model that combines a convolutional neural network (CNN) with Bayesian deep learning for oral cancer classification using small training sets. This approach employs variational inference to enhance reliability through uncertainty quantification. The model was trained on photographic color images captured by smartphones and evaluated on three distinct test datasets. The proposed method achieved 94% accuracy on a test dataset with a distribution similar to that of the training data, comparable to traditional CNN performance. Notably, for real-world photographic image data, despite limitations and variations differing from the training dataset, the proposed model demonstrated superior generalizability, achieving 88% accuracy on diverse datasets compared to 72.94% for traditional CNNs, even with a smaller dataset. Confidence analysis revealed that the model exhibits low uncertainty (high confidence) for correctly classified samples and high uncertainty (low confidence) for misclassified samples. These results underscore the effectiveness of Bayesian inference in data-scarce environments in enhancing early oral cancer diagnosis by improving model reliability and generalizability.

cs.CV↗