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Leo Kärkkäinen

Publications and source records attributed to Leo Kärkkäinen.

6 recordsLinked to original sources

Uncertainty-aware deep learning methods for robust diabetic retinopathy classification

Automatic classification of diabetic retinopathy from retinal images has been widely studied using deep neural networks with impressive results. However, there is a clinical need for estimation of the uncertainty in the classifications, a shortcoming of modern neural networks. Recently, approximate Bayesian deep learning methods have been proposed for the task but the studies have only considered the binary referable/non-referable diabetic retinopathy classification applied to benchmark datasets. We present novel results by systematically investigating a clinical dataset and a clinically relevant 5-class classification scheme, in addition to benchmark datasets and the binary classification scheme. Moreover, we derive a connection between uncertainty measures and classifier risk, from which we develop a new uncertainty measure. We observe that the previously proposed entropy-based uncertainty measure generalizes to the clinical dataset on the binary classification scheme but not on the 5-class scheme, whereas our new uncertainty measure generalizes to the latter case.

cs.CV↗

Estimation of groundwater storage from seismic data using deep learning

Convolutional neural networks can provide a potential framework to characterize groundwater storage from seismic data. Estimation of key components such as the amount of groundwater stored in an aquifer and delineate water-table level, from active-source seismic data are investigated in this study. The data to train, validate, and test the neural networks are obtained by solving wave propagation in a coupled poroviscoelastic-elastic media. A discontinuous Galerkin method is applied to model wave propagation whereas a deep convolutional neural network is used for the parameter estimation problem. In the numerical experiment, the primary unknowns are the amount of stored groundwater and water-table level, and are estimated, while the remaining parameters, assumed to be of less of interest, are marginalized in the convolutional neural networks-based solution. Results, obtained through synthetic data, illustrate the potential of deep learning methods to extract additional aquifer information from seismic data, which otherwise would be impossible based on a set of reflection seismic sections or velocity tomograms.

physics.comp-ph↗

Improving pulse transit time estimation of aortic PWV and blood pressure using machine learning and simulated training data

Recent developments in cardiovascular modelling allow us to simulate blood flow in an entire human body. Such model can also be used to create databases of virtual subjects, with sizes limited only by computational resources. In this work, we study if it is possible to estimate cardiovascular health indices using machine learning approaches. In particular, we carry out theoretical assessment of estimating aortic pulse wave velocity, diastolic and systolic blood pressure and stroke volume using pulse transit/arrival timings derived from photopletyshmography signals. For predictions, we train Gaussian process regression using a database of virtual subjects generated with a cardiovascular simulator. Simulated results provides theoretical assessment of accuracy for predictions of the health indices. For instance, aortic pulse wave velocity can be estimated with a high accuracy (r>0.9) when photopletyshmography is measured from left carotid artery using a combination of foot-to-foot pulse transmit time and peak location derived for the predictions. Similar accuracy can be reached for diastolic blood pressure, but predictions of systolic blood pressure are less accurate (r>0.75) and the stroke volume predictions are mostly contributed by heart rate.

physics.med-ph↗

Deep convolutional neural networks for estimating porous material parameters with ultrasound tomography

We study the feasibility of data based machine learning applied to ultrasound tomography to estimate water-saturated porous material parameters. In this work, the data to train the neural networks is simulated by solving wave propagation in coupled poroviscoelastic-viscoelastic-acoustic media. As the forward model, we consider a high-order discontinuous Galerkin method while deep convolutional neural networks are used to solve the parameter estimation problem. In the numerical experiment, we estimate the material porosity and tortuosity while the remaining parameters which are of less interest are successfully marginalized in the neural networks-based inversion. Computational examples confirms the feasibility and accuracy of this approach.

physics.comp-ph↗

Bidirectional Recurrent Neural Networks as Generative Models - Reconstructing Gaps in Time Series

Bidirectional recurrent neural networks (RNN) are trained to predict both in the positive and negative time directions simultaneously. They have not been used commonly in unsupervised tasks, because a probabilistic interpretation of the model has been difficult. Recently, two different frameworks, GSN and NADE, provide a connection between reconstruction and probabilistic modeling, which makes the interpretation possible. As far as we know, neither GSN or NADE have been studied in the context of time series before. As an example of an unsupervised task, we study the problem of filling in gaps in high-dimensional time series with complex dynamics. Although unidirectional RNNs have recently been trained successfully to model such time series, inference in the negative time direction is non-trivial. We propose two probabilistic interpretations of bidirectional RNNs that can be used to reconstruct missing gaps efficiently. Our experiments on text data show that both proposed methods are much more accurate than unidirectional reconstructions, although a bit less accurate than a computationally complex bidirectional Bayesian inference on the unidirectional RNN. We also provide results on music data for which the Bayesian inference is computationally infeasible, demonstrating the scalability of the proposed methods.

cs.LG↗

Interface Tension in Quenched QCD

We calculate the tension $σ$ of the interface between the confined and deconfined phases by the histogram method in SU(3) lattice gauge theory for temporal extents of 4 and 6 using the recent high-statistics data by QCDPAX collaboration. The results are $σ/T_c^3 = 0.0292(22)$ and 0.0218(33) for $N_t=4$ and 6, respectively. The ratio $σ/T_c^3$ shows a scaling violation similar to that already observed for the latent heat $\latent$. However, we find that the physically interesting dimensionless combinations $(σ^{3}/\latent^2 T)^{1/2}$ and $σT/ \latent$ scale within the statistical errors.

hep-lat↗