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Leonardo Angelini

Publications and source records attributed to Leonardo Angelini.

15 recordsLinked to original sources

Synergistic information in a dynamical model implemented on the human structural connectome reveals spatially distinct associations with age

We implement the dynamical Ising model on the large scale architecture of white matter connections of healthy subjects in the age range 4-85 years, and analyze the dynamics in terms of the synergy, a quantity measuring the extent to which the joint state of pairs of variables is projected onto the dynamics of a target one. We find that the amount of synergy in explaining the dynamics of the hubs of the structural connectivity (in terms of degree strength) peaks before the critical temperature, and can thus be considered as a precursor of a critical transition. Conversely the greatest amount of synergy goes into explaining the dynamics of more central nodes. We also find that the aging of the structural connectivity is associated to significant changes in the simulated dynamics: there are brain regions whose synergy decreases with age, in particular the frontal pole, the Subcallosal area and the Supplementary Motor area; these areas could then be more likely to show a decline in terms of the capability to perform higher order computation (if structural connectivity was the sole variable). On the other hand, several regions in the temporal cortex show a positive correlation with age in the first 30 years of life, i.e. during brain maturation.

q-bio.NC

Synergy as a warning sign of transitions: the case of the two-dimensional Ising model

We consider the formalism of information decomposition of target effects from multi-source interactions, i.e. the problem of defining redundant and synergistic components of the information that a set of source variables provides about a target, and apply it to the two-dimensional Ising model as a paradigm of a critically transitioning system. Intuitively, synergy is the information about the target variable that is uniquely obtained taking the sources together, but not considering them alone; redundancy is the information which is shared by the sources. To disentangle the components of the information both at the static level and at the dynamical one, the decomposition is applied respectively to the mutual information and to the transfer entropy between a given spin, the target, and a pair of neighbouring spins (taken as the drivers). We show that a key signature of an impending phase transition (approached from the disordered size) is the fact that the synergy peaks in the disordered phase, both in the static and in the dynamic case: the synergy can thus be considered a precursor of the transition. The redundancy, instead, reaches its maximum at the critical temperature. The peak of the synergy of the transfer entropy is far more pronounced than those of the static mutual information. We show that these results are robust w.r.t. the details of the information decomposition approach, as we find the same results using two different methods; moreover, w.r.t. previous literature rooted on the notion of Global Transfer Entropy, our results demonstrate that considering as few as three variables is sufficient to construct a precursor of the transition, and provide a paradigm for the investigation of a variety of systems prone to crisis, like financial markets, social media, or epileptic seizures.

cond-mat.stat-mech

Internet of Tangible Things (IoTT): Challenges and Opportunities for Tangible Interaction with IoT

In the Internet of Things era, an increasing number of household devices and everyday objects are able to send to and retrieve information from the Internet, offering innovative services to the user. However, most of these devices provide only smartphone or web interfaces to control the IoT object properties and functions. As a result, generally, the interaction is disconnected from the physical world, decreasing the user experience and increasing the risk of isolating the user in digital bubbles. We argue that tangible interaction can counteract this trend and this paper discusses the potential benefits and the still open challenges of tangible interaction applied to the Internet of Things. To underline this need, we introduce the term Internet of Tangible Things. In the article, after an analysis of current open challenges for Human-Computer Interaction in IoT, we summarize current trends in tangible interaction and extrapolate eight tangible interaction properties that could be exploited for designing novel interactions with IoT objects. Through a systematic literature review of tangible interaction applied to IoT, we show what has been already explored in the systems that pioneered the field and the future explorations that still have to be conducted.

cs.HC

Consensus clustering approach to group brain connectivity matrices

A novel approach rooted on the notion of consensus clustering, a strategy developed for community detection in complex networks, is proposed to cope with the heterogeneity that characterizes connectivity matrices in health and disease. The method can be summarized as follows: (i) define, for each node, a distance matrix for the set of subjects by comparing the connectivity pattern of that node in all pairs of subjects; (ii) cluster the distance matrix for each node; (iii) build the consensus network from the corresponding partitions; (iv) extract groups of subjects by finding the communities of the consensus network thus obtained. Differently from the previous implementations of consensus clustering, we thus propose to use the consensus strategy to combine the information arising from the connectivity patterns of each node. The proposed approach may be seen either as an exploratory technique or as an unsupervised pre-training step to help the subsequent construction of a supervised classifier. Applications on a toy model and two real data sets, show the effectiveness of the proposed methodology, which represents heterogeneity of a set of subjects in terms of a weighted network, the consensus matrix.

q-bio.NC

Conserved Ising Model on the Human Connectome

Dynamical models implemented on the large scale architecture of the human brain may shed light on how function arises from the underlying structure. This is the case notably for simple abstract models, such as the Ising model. We compare the spin correlations of the Ising model and the empirical functional brain correlations, both at the single link level and at the modular level, and show that their match increases at the modular level in anesthesia, in line with recent results and theories. Moreover, we show that at the peak of the specific heat (the \it{critical state}) the spin correlations are minimally shaped by the underlying structural network, explaining how the best match between structure and function is obtained at the onset of criticality, as previously observed. These findings confirm that brain dynamics under anesthesia shows a departure from criticality and could open the way to novel perspectives when the conserved magnetization is interpreted in terms of an homeostatic principle imposed to neural activity.

q-bio.NC

Synergetic and redundant information flow detected by unnormalized Granger causality: application to resting state fMRI

Objectives: We develop a framework for the analysis of synergy and redundancy in the pattern of information flow between subsystems of a complex network. Methods: The presence of redundancy and/or synergy in multivariate time series data renders difficult to estimate the neat flow of information from each driver variable to a given target. We show that adopting an unnormalized definition of Granger causality one may put in evidence redundant multiplets of variables influencing the target by maximizing the total Granger causality to a given target, over all the possible partitions of the set of driving variables. Consequently we introduce a pairwise index of synergy which is zero when two independent sources additively influence the future state of the system, differently from previous definitions of synergy. Results: We report the application of the proposed approach to resting state fMRI data from the Human Connectome Project, showing that redundant pairs of regions arise mainly due to space contiguity and interhemispheric symmetry, whilst synergy occurs mainly between non-homologous pairs of regions in opposite hemispheres. Conclusions: Redundancy and synergy, in healthy resting brains, display characteristic patterns, revealed by the proposed approach. Significance: The pairwise synergy index, here introduced, maps the informational character of the system at hand into a weighted complex network: the same approach can be applied to other complex systems whose normal state corresponds to a balance between redundant and synergetic circuits.

cs.IT

Information transfer of an Ising model on a brain network

We implement the Ising model on a structural connectivity matrix describing the brain at a coarse scale. Tuning the model temperature to its critical value, i.e. at the susceptibility peak, we find a maximal amount of total information transfer between the spin variables. At this point the amount of information that can be redistributed by some nodes reaches a limit and the net dynamics exhibits signature of the law of diminishing marginal returns, a fundamental principle connected to saturated levels of production. Our results extend the recent analysis of dynamical oscillators models on the connectome structure, taking into account lagged and directional influences, focusing only on the nodes that are more prone to became bottlenecks of information. The ratio between the outgoing and the incoming information at each node is related to the number of incoming links.

q-bio.NC

Information flow in a network model and the law of diminishing marginal returns

We analyze a simple dynamical network model which describes the limited capacity of nodes to process the input information. For a suitable choice of the parameters, the information flow pattern is characterized by exponential distribution of the incoming information and a fat-tailed distribution of the outgoing information, as a signature of the law of diminishing marginal returns. The analysis of a real EEG data-set shows that similar phenomena may be relevant for brain signals.

physics.data-an

Granger causality for circular variables

In this letter we discuss use of Granger causality to the analyze systems of coupled circular variables, by modifying a recently proposed method for multivariate analysis of causality. We show the application of the proposed approach on several Kuramoto systems, in particular one living on networks built by preferential attachment and a model for the transition from deeply to lightly anaesthetized states. Granger causalities describe the flow of information among variables.

cond-mat.dis-nn

Identification of network modules by optimization of ratio association

We introduce a novel method for identifying the modular structures of a network based on the maximization of an objective function: the ratio association. This cost function arises when the communities detection problem is described in the probabilistic autoencoder frame. An analogy with kernel k-means methods allows to develop an efficient optimization algorithm, based on the deterministic annealing scheme. The performance of the proposed method is shown on a real data set and on simulated networks.

cond-mat.dis-nn

Semi-supervised learning by search of optimal target vector

We introduce a semi-supervised learning estimator which tends to the first kernel principal component as the number of labelled points vanishes. Our approach is based on the notion of optimal target vector, which is defined as follows. Given an input data-set of ${\bf x}$ values, the optimal target vector $\mathbf{y}$ is such that treating it as the target and using kernel ridge regression to model the dependency of $y$ on ${\bf x}$, the training error achieves its minimum value. For an unlabeled data set, the first kernel principal component is the optimal vector. In the case one is given a partially labeled data set, still one may look for the optimal target vector minimizing the training error. We use this new estimator in two directions. As a substitute of kernel principal component analysis, in the case one has some labeled data, to produce dimensionality reduction. Second, to develop a semi-supervised regression and classification algorithm for transductive inference. We show application of the proposed method in both directions.

cond-mat.dis-nn

Kernel method for clustering based on optimal target vector

We introduce the notion of optimal target vector, and describe how it creates a link between supervised and unsupervised learning. We exploit this notion to construct Ising models, for dichotomic clustering, whose couplings are (i) both ferro- and anti-ferromagnetic (ii) depending on the whole data-set and not only on pairs of samples. The effectiveness of the method is shown in the case of the well known iris data-set and in benchmarks of gene expression levels.

cond-mat.dis-nn

Antiferromagnetic effects in Chaotic Map lattices with a conservation law

Some results about phase separation in coupled map lattices satisfying a conservation law are presented. It is shown that this constraint is the origin of interesting antiferromagnetic effective couplings and allows transitions to antiferromagnetic and superantiferromagnetic phases. Similarities and differences between this models and statistical spin models are pointed out.

cond-mat.dis-nn

Phase Ordering in Chaotic Map Lattices with Additive Noise

We present some result about phase separation in coupled map lattices with additive noise. We show that additive noise acts as an ordering agent in this class of systems. In particular, in the weak coupling region, a suitable quantity of noise leads to complete ordering. Extrapolating our results at small coupling, we deduce that this phenomenon could take place also in the limit of zero coupling.

cond-mat.dis-nn

Phase ordering in chaotic map lattices with conserved dynamics

Dynamical scaling in a two-dimensional lattice model of chaotic maps, in contact with a thermal bath, is numerically studied. The model here proposed is equivalent to a conserved Ising model with coupligs which fluctuate over the same time scale as spin moves. When couplings fluctuations and thermal fluctuations are both important, this model does not belong to the class of universality of a Langevin equation known as model B; the scaling exponents are continuously varying with the temperature and depend on the map used. The universal behavior of model B is recovered when thermal fluctuations are dominant.

cond-mat.stat-mech