arXiv subjects

Li Xiao

Publications and source records attributed to Li Xiao.

At least 19 recordsLinked to original sources

arXiv2026

A multi-scale feature enhanced graph neural network for fluid dynamics prediction in complex geometries

Industrial design in fields such as vehicle and aerospace engineering often relies on large-scale numerical simulations to evaluate fluid dynamics performance, which can incur substantial computational costs. Deep neural networks have shown promise in improving simulation efficiency, especially graph neural networks (GNNs), which demonstrate great potential due to their flexibility with unstructured data. However, GNNs face challenges when dealing with tasks involving complex geometries and large-scale meshes. In this paper, we propose the Multi-scale Feature Enhanced Graph Neural Network (ME-GNN) to tackle these challenges. ME-GNN employs a graph neural network with a two-step message-passing mechanism to capture detailed local features effectively. Additionally, it integrates an Attention U-Net with uniform grid discretization, enabling the extraction of both fine and coarse features. The model also utilizes K-hop sampling to construct subgraphs, facilitating efficient training on large datasets while preserving detailed local features. We evaluated ME-GNN on three benchmark datasets and achieved state-of-the-art results: a relative L2 error of 0.0196 for the velocity field and 0.0556 for the surface pressure on ShapeNet-Car, a normalized mean squared error of 0.0033 for the flow field on AirfRANS, and a relative L2 error of 0.1416 for the surface pressure on DrivAerNet.

cs.LG↗

arXiv2026

Consistent and Editable: A Balanced Framework for Text-Guided Video Editing

Recently, diffusion models have achieved considerable success in the text-guided video editing domain. However, existing works often struggle to balance the trade-off between temporal consistency and editability in video editing, with consistency and editability typically being inversely related. To address this, we propose a high-quality video editing framework enhanced for consistency and editability, named EquiEdit, which improves coordinatively the temporal consistency and editability of the edited videos while achieving a balance between the two. In terms of temporal consistency, the proposed temporal Mamba module with a tailored temporal-aware scanning scans fused video sequences following four designed directions, effectively enhancing the inter-frame consistency of edited videos. For editability, we design a noise injection strategy based on the spectral transformation to increase editing flexibility, where the Fourier transform is used to preserve the hidden structure in the initial latent noise used for editing, ensuring inter-frame consistency of the edited video and fidelity to the input video. Extensive qualitative and quantitative experiments demonstrate the effectiveness of our method in terms of temporal consistency and editability, as well as its great fidelity to the input video itself.

cs.CV↗

arXiv2026

Physics-Driven Zero-Shot MRI Reconstruction with Non-local Image Priors

Zero-Shot Self-Supervised Learning (ZS-SSL) has emerged as a promising paradigm for accelerated Magnetic Resonance Imaging (MRI) reconstruction, eliminating the reliance on fully-sampled external datasets. However, learning solely from a single under-sampled scan suffers from supervision scarcity and optimization instability, often leading to overfitting or artifacts. To address these challenges, we propose a robust physics-driven ZS-SSL framework that synergizes physical consistency with image-domain non-local priors. Our method introduces three core innovations: (1) a Coil Sensitivity Map (CSM)-Guided Dynamic Repository, which stabilizes the training trajectory by filtering physically inconsistent artifacts based on coil sensitivity constraints; (2) a SPIRiT-based regularization, which enforces k-space self-consistency via a learned correlation kernel and stochastic masking; (3) a Non-Local Self-Similarity (NSS) Pixel Bank, which leverages the high-fidelity reference established by the former modules to explicitly mine non-local anatomical similarities, thereby augmenting supervision in the image domain. Extensive experiments on the FastMRI dataset demonstrate that our approach achieves state-of-the-art performance, particularly under high acceleration factors, effectively bridging the gap between zero-shot learning and supervised methods. The code is available at https://github.com/Zolento/NS-SSL.

cs.CV↗

arXiv2026

BrainCast: A Spatio-Temporal Forecasting Model for Whole-Brain fMRI Time Series Prediction

Functional magnetic resonance imaging (fMRI) enables noninvasive investigation of brain function, while short clinical scan durations, arising from human and non-human factors, usually lead to reduced data quality and limited statistical power for neuroimaging research. In this paper, we propose BrainCast, a novel spatio-temporal forecasting framework specifically tailored for whole-brain fMRI time series forecasting, to extend informative fMRI time series without additional data acquisition. It formulates fMRI time series forecasting as a multivariate time series prediction task and jointly models temporal dynamics within regions of interest (ROIs) and spatial interactions across ROIs. Specifically, BrainCast integrates a Spatial Interaction Awareness module to characterize inter-ROI dependencies via embedding every ROI time series as a token, a Temporal Feature Refinement module to capture intrinsic neural dynamics within each ROI by enhancing both low- and high-energy temporal components of fMRI time series at the ROI level, and a Spatio-temporal Pattern Alignment module to combine spatial and temporal representations for producing informative whole-brain features. Experimental results on resting-state and task fMRI datasets from the Human Connectome Project demonstrate the superiority of BrainCast over state-of-the-art time series forecasting baselines. Moreover, fMRI time series extended by BrainCast improve downstream cognitive ability prediction, highlighting the clinical and neuroscientific impact brought by whole-brain fMRI time series forecasting in scenarios with restricted scan durations.

cs.CV↗

arXiv2026

DDS-UDA: Dual-Domain Synergy for Unsupervised Domain Adaptation in Joint Segmentation of Optic Disc and Optic Cup

Convolutional neural networks (CNNs) have achieved exciting performance in joint segmentation of optic disc and optic cup on single-institution datasets. However, their clinical translation is hindered by two major challenges: limited availability of large-scale, high-quality annotations and performance degradation caused by domain shift during deployment across heterogeneous imaging protocols and acquisition platforms. While unsupervised domain adaptation (UDA) provides a way to mitigate these limitations, most existing approaches do not address cross-domain interference and intra-domain generalization within a unified framework. In this paper, we present the Dual-Domain Synergy UDA (DDS-UDA), a novel UDA framework that comprises two key modules. First, a bi-directional cross-domain consistency regularization module is enforced to mitigate cross-domain interference through feature-level semantic information exchange guided by a coarse-to-fine dynamic mask generator, suppressing noise propagation while preserving structural coherence. Second, a frequency-driven intra-domain pseudo label learning module is used to enhance intra-domain generalization by synthesizing spectral amplitude-mixed supervision signals, which ensures high-fidelity feature alignment across domains. Implemented within a teacher-student architecture, DDS-UDA disentangles domain-specific biases from domain-invariant feature-level representations, thereby achieving robust adaptation to heterogeneous imaging environments. We conduct a comprehensive evaluation of our proposed method on two multi-domain fundus image datasets, demonstrating that it outperforms several existing UDA based methods and therefore providing an effective way for optic disc and optic cup segmentation.

cs.CV↗

arXiv2026

FCN-LLM: Empower LLM for Brain Functional Connectivity Network Understanding via Graph-level Multi-task Instruction Tuning

Large Language Models have achieved remarkable success in language understanding and reasoning, and their multimodal extensions enable comprehension of images, video, and audio. Inspired by this, foundation models for brain functional connectivity networks derived from resting-state fMRI have shown promise in clinical tasks. However, existing methods do not align FCNs with the text modality, limiting the ability of LLMs to directly understand FCNs. To address this, we propose FCN-LLM, a framework that enables LLMs to understand FCNs through graph-level, multi-task instruction tuning. Our approach employs a multi-scale FCN encoder capturing brain-region, functional subnetwork, and whole-brain features, projecting them into the semantic space of LLM. We design multi-paradigm instruction tasks covering 19 subject-specific attributes across demographics, phenotypes, and psychiatric conditions. A multi-stage learning strategy first aligns FCN embeddings with the LLM and then jointly fine-tunes the entire model to capture high-level semantic information. Experiments on a large-scale, multi-site FCN database show that FCN-LLM achieves strong zero-shot generalization on unseen datasets, outperforming conventional supervised and foundation models. This work introduces a new paradigm for integrating brain functional networks with LLMs, offering a flexible and interpretable framework for neuroscience.

cs.AI↗

arXiv2026

ATPO: Adaptive Tree Policy Optimization for Multi-Turn Medical Dialogue

Effective information seeking in multi-turn medical dialogues is critical for accurate diagnosis, especially when dealing with incomplete information. Aligning Large Language Models (LLMs) for these interactive scenarios is challenging due to the uncertainty inherent in user-agent interactions, which we formulate as a Hierarchical Markov Decision Process (H-MDP). While conventional Reinforcement Learning (RL) methods like Group Relative Policy Optimization (GRPO) struggle with long-horizon credit assignment and Proximal Policy Optimization (PPO) suffers from unstable value estimation in this context, we propose a novel uncertainty-aware Adaptive Tree Policy Optimization (ATPO) algorithm. Our method adaptively allocates the rollout budget to states with high uncertainty, quantified by a composite metric of Bellman error and action-value variance. This strategy enables more accurate value estimation, while fostering more efficient and diverse exploration. To mitigate the high computational cost of tree-based RL, we introduce two key optimizations: an uncertainty-guided pruning mechanism to minimize the number of rollouts, and an asynchronous search architecture that leverages KV cache reuse to maximize inference throughput. Extensive experiments on three public medical dialogue benchmarks demonstrate that our algorithm significantly outperforms several strong baselines, culminating in Qwen3-8B model surpassing the much larger GPT-4o ($+0.92\%$ accuracy).

cs.LG↗

arXiv2026

ReGLA: Efficient Receptive-Field Modeling with Gated Linear Attention Network

Balancing accuracy and latency on high-resolution images is a critical challenge for lightweight models, particularly for Transformer-based architectures that often suffer from excessive latency. To address this issue, we introduce \textbf{ReGLA}, a series of lightweight hybrid networks, which integrates efficient convolutions for local feature extraction with ReLU-based gated linear attention for global modeling. The design incorporates three key innovations: the Efficient Large Receptive Field (ELRF) module for enhancing convolutional efficiency while preserving a large receptive field; the ReLU Gated Modulated Attention (RGMA) module for maintaining linear complexity while enhancing local feature representation; and a multi-teacher distillation strategy to boost performance on downstream tasks. Extensive experiments validate the superiority of ReGLA; particularly the ReGLA-M achieves \textbf{80.85\%} Top-1 accuracy on ImageNet-1K at $224px$, with only \textbf{4.98 ms} latency at $512px$. Furthermore, ReGLA outperforms similarly scaled iFormer models in downstream tasks, achieving gains of \textbf{3.1\%} AP on COCO object detection and \textbf{3.6\%} mIoU on ADE20K semantic segmentation, establishing it as a state-of-the-art solution for high-resolution visual applications.

cs.CV↗

arXiv2026

FUGC: Benchmarking Semi-Supervised Learning Methods for Cervical Segmentation

Accurate segmentation of cervical structures in transvaginal ultrasound (TVS) is critical for assessing the risk of spontaneous preterm birth (PTB), yet the scarcity of labeled data limits the performance of supervised learning approaches. This paper introduces the Fetal Ultrasound Grand Challenge (FUGC), the first benchmark for semi-supervised learning in cervical segmentation, hosted at ISBI 2025. FUGC provides a dataset of 890 TVS images, including 500 training images, 90 validation images, and 300 test images. Methods were evaluated using the Dice Similarity Coefficient (DSC), Hausdorff Distance (HD), and runtime (RT), with a weighted combination of 0.4/0.4/0.2. The challenge attracted 10 teams with 82 participants submitting innovative solutions. The best-performing methods for each individual metric achieved 90.26\% mDSC, 38.88 mHD, and 32.85 ms RT, respectively. FUGC establishes a standardized benchmark for cervical segmentation, demonstrates the efficacy of semi-supervised methods with limited labeled data, and provides a foundation for AI-assisted clinical PTB risk assessment.

eess.IV↗

arXiv2025

WSD-MIL: Window Scale Decay Multiple Instance Learning for Whole Slide Image Classification

In recent years, the integration of pre-trained foundational models with multiple instance learning (MIL) has improved diagnostic accuracy in computational pathology. However, existing MIL methods focus on optimizing feature extractors and aggregation strategies while overlooking the complex semantic relationships among instances within whole slide image (WSI). Although Transformer-based MIL approaches aiming to model instance dependencies, the quadratic computational complexity limits their scalability to large-scale WSIs. Moreover, due to the pronounced variations in tumor region scales across different WSIs, existing Transformer-based methods employing fixed-scale attention mechanisms face significant challenges in precisely capturing local instance correlations and fail to account for the distance-based decay effect of patch relevance. To address these challenges, we propose window scale decay MIL (WSD-MIL), designed to enhance the capacity to model tumor regions of varying scales while improving computational efficiency. WSD-MIL comprises: 1) a window scale decay based attention module, which employs a cluster-based sampling strategy to reduce computational costs while progressively decaying attention window-scale to capture local instance relationships at varying scales; and 2) a squeeze-and-excitation based region gate module, which dynamically adjusts window weights to enhance global information modeling. Experimental results demonstrate that WSD-MIL achieves state-of-the-art performance on the CAMELYON16 and TCGA-BRCA datasets while reducing 62% of the computational memory. The code will be publicly available.

cs.CV↗

arXiv2025

ESG Integration into Corporate Strategy Value Realization

Since the formal introduction of its "dual-carbon" strategy in 2020, China has witnessed the concepts of green development and sustainability evolve from policy directives into a broad societal consensus. Within this transformative context, the Environmental, Social, and Governance (ESG) framework has emerged as a critical enabler, mutually reinforcing and synergizing with the national strategic objectives of achieving carbon peak and carbon neutrality. This integration signifies a fundamental shift in corporate philosophy, urging enterprises to transcend a narrow focus on short-term financial metrics. To align with the national vision of ecological civilization and sustainable growth, companies are now expected to proactively fulfill their social responsibilities and pursue long-term, non-financial value creation. This entails a deep integration of ESG principles into the very core of corporate culture and strategy, ensuring their active implementation in daily operations and decision-making processes.

q-fin.GN↗

arXiv2025

AI-driven Large-scale Electron Microscopy enables Whole-tissue Subcellular Digitization

The distribution and interactions of cellular organelles play a critical role in mediating cellular physiology and pathology. Large-scale electron microscopy enables visualization of organelle distribution and interactions at the tissue level with nanometer resolution, but robust and efficient computational analysis tools are lacking. Here, we present a deep learning tool for universal large-scale 2D/3D electron microscopy analysis, DeepOrganelle. This new tool enables high-throughput, cell-resolved spatiotemporal mapping and digitization of organelle distribution and interactions. When applied to spermatogenesis across 12 stages and 22 differentiation status of the germ cells, DeepOrganelle uncovered previously unrecognized, stage-dependent dynamics of mitochondria-endoplasmic reticulum contact sites within one subphase of prophase I during meiosis. It also revealed coordinated organelle redistribution in Sertoli cells towards the blood-testis barrier, digitizing the remodeling dynamics of the tissue. This study demonstrates that DeepOrganelle provides a powerful framework that captures subcellular dynamics at the whole-tissue level.

physics.bio-ph↗

arXiv2025

MLF-4DRCNet: Multi-Level Fusion with 4D Radar and Camera for 3D Object Detection in Autonomous Driving

The emerging 4D millimeter-wave radar, measuring the range, azimuth, elevation, and Doppler velocity of objects, is recognized for its cost-effectiveness and robustness in autonomous driving. Nevertheless, its point clouds exhibit significant sparsity and noise, restricting its standalone application in 3D object detection. Recent 4D radar-camera fusion methods have provided effective perception. Most existing approaches, however, adopt explicit Bird's-Eye-View fusion paradigms originally designed for LiDAR-camera fusion, neglecting radar's inherent drawbacks. Specifically, they overlook the sparse and incomplete geometry of radar point clouds and restrict fusion to coarse scene-level integration. To address these problems, we propose MLF-4DRCNet, a novel two-stage framework for 3D object detection via multi-level fusion of 4D radar and camera images. Our model incorporates the point-, scene-, and proposal-level multi-modal information, enabling comprehensive feature representation. It comprises three crucial components: the Enhanced Radar Point Encoder (ERPE) module, the Hierarchical Scene Fusion Pooling (HSFP) module, and the Proposal-Level Fusion Enhancement (PLFE) module. Operating at the point-level, ERPE densities radar point clouds with 2D image instances and encodes them into voxels via the proposed Triple-Attention Voxel Feature Encoder. HSFP dynamically integrates multi-scale voxel features with 2D image features using deformable attention to capture scene context and adopts pooling to the fused features. PLFE refines region proposals by fusing image features, and further integrates with the pooled features from HSFP. Experimental results on the View-of-Delft (VoD) and TJ4DRadSet datasets demonstrate that MLF-4DRCNet achieves the state-of-the-art performance. Notably, it attains performance comparable to LiDAR-based models on the VoD dataset.

cs.CV↗

arXiv2025

Impact of Phonetics on Speaker Identity in Adversarial Voice Attack

Adversarial perturbations in speech pose a serious threat to automatic speech recognition (ASR) and speaker verification by introducing subtle waveform modifications that remain imperceptible to humans but can significantly alter system outputs. While targeted attacks on end-to-end ASR models have been widely studied, the phonetic basis of these perturbations and their effect on speaker identity remain underexplored. In this work, we analyze adversarial audio at the phonetic level and show that perturbations exploit systematic confusions such as vowel centralization and consonant substitutions. These distortions not only mislead transcription but also degrade phonetic cues critical for speaker verification, leading to identity drift. Using DeepSpeech as our ASR target, we generate targeted adversarial examples and evaluate their impact on speaker embeddings across genuine and impostor samples. Results across 16 phonetically diverse target phrases demonstrate that adversarial audio induces both transcription errors and identity drift, highlighting the need for phonetic-aware defenses to ensure the robustness of ASR and speaker recognition systems.

cs.SD↗

arXiv2025

PepThink-R1: LLM for Interpretable Cyclic Peptide Optimization with CoT SFT and Reinforcement Learning

Designing therapeutic peptides with tailored properties is hindered by the vastness of sequence space, limited experimental data, and poor interpretability of current generative models. To address these challenges, we introduce PepThink-R1, a generative framework that integrates large language models (LLMs) with chain-of-thought (CoT) supervised fine-tuning and reinforcement learning (RL). Unlike prior approaches, PepThink-R1 explicitly reasons about monomer-level modifications during sequence generation, enabling interpretable design choices while optimizing for multiple pharmacological properties. Guided by a tailored reward function balancing chemical validity and property improvements, the model autonomously explores diverse sequence variants. We demonstrate that PepThink-R1 generates cyclic peptides with significantly enhanced lipophilicity, stability, and exposure, outperforming existing general LLMs (e.g., GPT-5) and domain-specific baseline in both optimization success and interpretability. To our knowledge, this is the first LLM-based peptide design framework that combines explicit reasoning with RL-driven property control, marking a step toward reliable and transparent peptide optimization for therapeutic discovery.

cs.LG↗

arXiv2025

UniDCF: A Foundation Model for Comprehensive Dentocraniofacial Hard Tissue Reconstruction

Dentocraniofacial hard tissue defects profoundly affect patients' physiological functions, facial aesthetics, and psychological well-being, posing significant challenges for precise reconstruction. Current deep learning models are limited to single-tissue scenarios and modality-specific imaging inputs, resulting in poor generalizability and trade-offs between anatomical fidelity, computational efficiency, and cross-tissue adaptability. Here we introduce UniDCF, a unified framework capable of reconstructing multiple dentocraniofacial hard tissues through multimodal fusion encoding of point clouds and multi-view images. By leveraging the complementary strengths of each modality and incorporating a score-based denoising module to refine surface smoothness, UniDCF overcomes the limitations of prior single-modality approaches. We curated the largest multimodal dataset, comprising intraoral scans, CBCT, and CT from 6,609 patients, resulting in 54,555 annotated instances. Evaluations demonstrate that UniDCF outperforms existing state-of-the-art methods in terms of geometric precision, structural completeness, and spatial accuracy. Clinical simulations indicate UniDCF reduces reconstruction design time by 99% and achieves clinician-rated acceptability exceeding 94%. Overall, UniDCF enables rapid, automated, and high-fidelity reconstruction, supporting personalized and precise restorative treatments, streamlining clinical workflows, and enhancing patient outcomes.

cs.CV↗

arXiv2025

Sparse Phase Retrieval with Redundant Dictionary via $\ell_q (0<q\le 1)$-Analysis Model

Sparse phase retrieval with redundant dictionary is to reconstruct the signals of interest that are (nearly) sparse in a redundant dictionary or frame from the phaseless measurements via the optimization models. Gao [7] presented conditions on the measurement matrix, called null space property (NSP) and strong dictionary restricted isometry property (S-DRIP), for exact and stable recovery of dictionary-$k$-sparse signals via the $\ell_1$-analysis model for sparse phase retrieval with redundant dictionary, respectively, where, in particularly, the S-DRIP of order $tk$ with $t>1$ was derived. In this paper, motivated by many advantages of the $\ell_q$ minimization with $0<q\leq1$, e.g., reduction of the number of measurements required, we generalize these two conditions to the $\ell_q$-analysis model. Specifically, we first present two NSP variants for exact recovery of dictionary-$k$-sparse signals via the $\ell_q$-analysis model in the noiseless scenario. Moreover, we investigate the S-DRIP of order $tk$ with $0<t<\frac{4}{3}$ for stable recovery of dictionary-$k$-sparse signals via the $\ell_q$-analysis model in the noisy scenario, which will complement the existing result of the S-DRIP of order $tk$ with $t\geq2$ obtained in [4].

cs.IT↗

arXiv2025

A candidate for True Type-2 AGN without hidden central BLRs Identified by central Tidal Disruption Event

In this manuscript, through applications of TDE (tidal disruption event) expected variability properties, a potential candidate for True type-2 AGN without hidden central broad line regions (=TT2AGN) is reported in the SDSS J233454.07+145712.9 (=SDSS J2334). Through analyzing the 20-years optical light curves of SDSS J2334 from different Sky Survey projects, a TDE is preferred with a $4.7{\rm M_\odot}$ main-sequence star tidally disrupted by the central BH with mass $11.7\times 10^6{\rm M_\odot}$, indicating that central region within distance about 20 light-days to central BH in SDSS J2334 is directly in the line-of-sight. Moreover, AGN activities in SDSS J2334 can be confirmed through applications of BPT diagrams. Meanwhile, comparing virial BH mass determined through assumed broad Balmer emission components and M-sigma expected BH mass by well measured stellar velocity dispersion through stellar absorption features, optical broad emission lines in SDSS J2334 are disfavored with confidence level higher than 6$\sigma$. Therefore, combining the unique properties of the TDE and the spectroscopic results with only narrow emission lines, SDSS J2334 can be well identified as a potential candidate for a TT2AGN. The results indicate the to detect TDE expected flares in normal Type-2 AGN classified by spectroscopic results should be a new practicable method for identifying

astro-ph.GA↗