Searcharxiv⌕ Search

arXiv subjects

Li Xiao

Publications and source records attributed to Li Xiao.

At least 19 recordsLinked to original sources
arXiv2026

Do 3D Large Language Models Really Use 3D Evidence?

Recent 3D Large Language Models (3D-LLMs) have shown strong performance on scene question answering with extensive post-training. Yet, existing benchmarks rarely evaluate how 3D-LLMs respond to referential ambiguity, insufficient scene evidence, or false presuppositions, obscuring whether their responses are grounded in 3D evidence. In this work, we introduce UNICORNS, a benchmark for evaluating the reliability of 3D-LLM responses across four evidence conditions. UNICORNS contains 11,387 questions across 557 ScanNet scans, covering eight challenge categories alongside answerable controls. A response passes only if it satisfies the required response behavior and contains no scene claim unsupported by the available evidence. Evaluation of six open-sourced 3D-LLMs reveals a pronounced performance gap: even the strongest zero-shot model achieves 61.22% accuracy on answerable controls, but only 40.94% across the eight challenge categories. To address this gap, we further propose HORN, an obligation-aware post-training method combining group-relative task rewards, leaf-conditioned obligation rewards, and supervised control replay. Extensive experiments demonstrate that HORN reaches $75.1 \pm 1.0\%$ across the challenge categories and $77.2 \pm 0.8\%$ overall, outperforming all baselines without degrading answerable-control accuracy. Our findings enable a systematic evaluation and improvement of evidence-grounded 3D reasoning for 3D-LLMs (code: https://anonymous.4open.science/r/unicorns-6B38/).

cs.CV↗
arXiv2026

PAC-KD: Pathology-Aware Compositional Knowledge Distillation for Respiratory Sound Classification

Respiratory sound classification distinguishes four categories: Normal, Crackle, Wheeze, and Both (crackle and wheeze). Existing knowledge distillation transfers four-class predictions without explicitly exploiting shared respiratory events, potentially limiting the transfer of event-specific knowledge across individual abnormal classes and the Both class. We propose PAC-KD, a pathology-aware compositional knowledge distillation framework that learns crackle and wheeze presence through two dedicated specialists. Their complementary knowledge is transferred to a unified four-class student, enabling it to effectively capture pathology-specific attributes while preserving class-level discrimination. Furthermore, stable conflict calibration adaptively regulates specialist guidance according to its consistency with classification supervision, mitigating potential supervision conflicts. Experiments on ICBHI and SPRSound achieve Scores of 65.28\% and 89.54\%, respectively, outperforming strong knowledge distillation baselines on both datasets.

cs.SD↗
arXiv2026

Clinically Informed Acoustic-Aware Attribute Modeling for Respiratory Sound Classification

Automated respiratory sound classification (RSC) aims to identify normal and adventitious respiratory sounds, such as crackles and wheezes. Most existing methods formulate RSC as a flat four-class classification problem over norma, crackle, wheeze and both. However, unlike conventional classification tasks with semantically independent and mutually exclusive categories, the commonly used four-class RSC labels have a compositional structure and can be represented by two clinically meaningful sound attributes: crackle presence and wheeze presence. Existing flat classifiers do not explicitly exploit this structure, which may increase the learning burden by treating the four labels as independent targets. Meanwhile, crackles and wheezes exhibit distinct temporal characteristics, with sparse transient crackle events and sustained continuous wheeze patterns, making a single temporal aggregation strategy less suitable for modeling different adventitious sound evidence. To address these limitations, we propose an Acoustic-Aware Asymmetric Framework (AAAF) for RSC. AAAF reformulates four-class recognition as two sound-attribute detection tasks and recovers the final category through logical composition during inference. Built upon a pretrained BEATs encoder, AAAF employs branch-specific multi-layer fusion and asymmetric temporal aggregation to capture localized crackle evidence and sustained wheeze patterns. Auxiliary normal--abnormal supervision and a batch-adaptive dynamic loss are further introduced to improve global discrimination and robustness under imbalanced labels. Experiments on ICBHI and SPRSound demonstrate that AAAF improves overall RSC performance and generalizes across datasets, achieving a state-of-the-art four-class Score of 65.30% on ICBHI.

cs.SD↗
arXiv2026

MemCalib: Benchmarking and Optimizing Memory Use in LLM Agents

The effectiveness of agent memory ultimately depends on whether the underlying LLM gives each memory in context an appropriate degree of influence over its response. Yet this capability has remained largely overlooked. To assess this capability, we introduce MemCalib, a benchmark grounded in realistic memory-system scenarios for evaluating memory use and advancing optimization algorithms. Results on the MemCalib test set reveal that frontier open- and closed-source models struggle to use memory appropriately. They frequently over-use or under-use memory rather than matching each proposition's actual use to its target level, leading to biased, low-quality responses. Experiments with common post-training algorithms, including group relative policy optimization and on-policy self-distillation, further reveal a clear directional skew: trained models improve in one direction while deteriorating in the other. We therefore propose MemCalib-RL, an ordered bidirectional counterfactual credit-assignment algorithm that separates over- and under-use signals and localizes their credit to response tokens through exact atom ablation. Results across model families and scales (Qwen3-8B, Ministral-3-8B-Instruct, and Qwen3.5-35B-A3B) show that MemCalib-RL achieves the best overall performance while better balancing over-use and under-use, with gains generalizing beyond MemCalib in external benchmark evaluation. Further experiments support its design choices and robustness and provide insight into its training dynamics.

cs.LG↗
arXiv2026

Discovery of Kolmogorov-like turbulence in the inner shell of SNR HB 9

We investigated the scaling relation of the magnetohydrodynamic turbulence in the inner and outer shells of the supernova remnant HB 9 using multi-tracers. For the eastern inner shell section, one-dimensional structure function and power spectrum analyses of the radio total intensity, H-alpha emission, and polarized intensity consistently show a Kolmogorov-like scaling of l^2/3 over the inertial range. The two-dimensional power spectrum for the entire inner region follows k^-8/3 of all tracers, including the polarization gradient. It indicates that fully developed, trans-Alfvenic Kolmogorov turbulence is present in the inner shell of HB 9. We estimated the strength of random magnetic field therein from the low fractional polarization (5%), and obtained a upper limit delta B of 18 micro G. The turbulence in the inner shock shell is most likely driven by the Richtmyer-Meshkov instability.

astro-ph.GA↗
arXiv2026

COPE: Continual Personalization of LLMs under Sparse User Feedback via User Embeddings and Self-Evaluation

While Large Language Models (LLMs) have achieved remarkable results across various benchmarks, their alignment with normative values often results in homogenized responses that fail to address diverse user preferences. Existing training-free methods often occupy valuable context windows through prompt engineering, while training-based methods typically remain static post-training, failing to support the continual optimization required in real-world settings. To address these challenges, we propose COPE (Continual Optimization with Personalized embedding and self-Evaluation), a novel optimization framework tailored for real-world-motivated interaction settings with sparse user feedback. Our framework assigns learnable personalized embeddings to each user and synergistically integrates preference capture, self-evaluation calibration, and personalized response optimization within a single update step. A key innovation of our method is the use of self-evaluation to generate proxy rewards, enabling continuous model updates even when explicit user feedback is unavailable. Experiments show that COPE consistently outperforms strong training-free and training-based baselines under sparse feedback, and remains complementary to Retrieval-Augmented Prompting (RAP). Further analyses confirm COPE's reliable self-evaluation, meaningful preference patterns, stable general capabilities, and robustness under shifting preferences and alternative evaluators.

cs.LG↗
arXiv2026

A multi-scale feature enhanced graph neural network for fluid dynamics prediction in complex geometries

Industrial design in fields such as vehicle and aerospace engineering often relies on large-scale numerical simulations to evaluate fluid dynamics performance, which can incur substantial computational costs. Deep neural networks have shown promise in improving simulation efficiency, especially graph neural networks (GNNs), which demonstrate great potential due to their flexibility with unstructured data. However, GNNs face challenges when dealing with tasks involving complex geometries and large-scale meshes. In this paper, we propose the Multi-scale Feature Enhanced Graph Neural Network (ME-GNN) to tackle these challenges. ME-GNN employs a graph neural network with a two-step message-passing mechanism to capture detailed local features effectively. Additionally, it integrates an Attention U-Net with uniform grid discretization, enabling the extraction of both fine and coarse features. The model also utilizes K-hop sampling to construct subgraphs, facilitating efficient training on large datasets while preserving detailed local features. We evaluated ME-GNN on three benchmark datasets and achieved state-of-the-art results: a relative L2 error of 0.0196 for the velocity field and 0.0556 for the surface pressure on ShapeNet-Car, a normalized mean squared error of 0.0033 for the flow field on AirfRANS, and a relative L2 error of 0.1416 for the surface pressure on DrivAerNet.

cs.LG↗
arXiv2026

Consistent and Editable: A Balanced Framework for Text-Guided Video Editing

Recently, diffusion models have achieved considerable success in the text-guided video editing domain. However, existing works often struggle to balance the trade-off between temporal consistency and editability in video editing, with consistency and editability typically being inversely related. To address this, we propose a high-quality video editing framework enhanced for consistency and editability, named EquiEdit, which improves coordinatively the temporal consistency and editability of the edited videos while achieving a balance between the two. In terms of temporal consistency, the proposed temporal Mamba module with a tailored temporal-aware scanning scans fused video sequences following four designed directions, effectively enhancing the inter-frame consistency of edited videos. For editability, we design a noise injection strategy based on the spectral transformation to increase editing flexibility, where the Fourier transform is used to preserve the hidden structure in the initial latent noise used for editing, ensuring inter-frame consistency of the edited video and fidelity to the input video. Extensive qualitative and quantitative experiments demonstrate the effectiveness of our method in terms of temporal consistency and editability, as well as its great fidelity to the input video itself.

cs.CV↗
arXiv2026

Physics-Driven Zero-Shot MRI Reconstruction with Non-local Image Priors

Zero-Shot Self-Supervised Learning (ZS-SSL) has emerged as a promising paradigm for accelerated Magnetic Resonance Imaging (MRI) reconstruction, eliminating the reliance on fully-sampled external datasets. However, learning solely from a single under-sampled scan suffers from supervision scarcity and optimization instability, often leading to overfitting or artifacts. To address these challenges, we propose a robust physics-driven ZS-SSL framework that synergizes physical consistency with image-domain non-local priors. Our method introduces three core innovations: (1) a Coil Sensitivity Map (CSM)-Guided Dynamic Repository, which stabilizes the training trajectory by filtering physically inconsistent artifacts based on coil sensitivity constraints; (2) a SPIRiT-based regularization, which enforces k-space self-consistency via a learned correlation kernel and stochastic masking; (3) a Non-Local Self-Similarity (NSS) Pixel Bank, which leverages the high-fidelity reference established by the former modules to explicitly mine non-local anatomical similarities, thereby augmenting supervision in the image domain. Extensive experiments on the FastMRI dataset demonstrate that our approach achieves state-of-the-art performance, particularly under high acceleration factors, effectively bridging the gap between zero-shot learning and supervised methods. The code is available at https://github.com/Zolento/NS-SSL.

cs.CV↗
arXiv2026

ESG Integration into Corporate Strategy Value Realization

Since the formal introduction of its "dual-carbon" strategy in 2020, China has witnessed the concepts of green development and sustainability evolve from policy directives into a broad societal consensus. Within this transformative context, the Environmental, Social, and Governance (ESG) framework has emerged as a critical enabler, mutually reinforcing and synergizing with the national strategic objectives of achieving carbon peak and carbon neutrality. This integration signifies a fundamental shift in corporate philosophy, urging enterprises to transcend a narrow focus on short-term financial metrics. To align with the national vision of ecological civilization and sustainable growth, companies are now expected to proactively fulfill their social responsibilities and pursue long-term, non-financial value creation. This entails a deep integration of ESG principles into the very core of corporate culture and strategy, ensuring their active implementation in daily operations and decision-making processes.

q-fin.GN↗
arXiv2026

PepThink-R1: LLM for Interpretable Cyclic Peptide Optimization with CoT SFT and Reinforcement Learning

Designing therapeutic peptides with tailored properties is hindered by the vastness of sequence space, limited experimental data, and poor interpretability of current generative models. To address these challenges, we introduce PepThink-R1, a generative framework that integrates large language models (LLMs) with chain-of-thought (CoT) supervised fine-tuning and reinforcement learning (RL). Unlike prior approaches, PepThink-R1 explicitly reasons about monomer-level modifications during sequence generation, enabling interpretable design choices while optimizing for multiple pharmacological properties. Guided by a tailored reward function balancing chemical validity and property improvements, the model autonomously explores diverse sequence variants. We demonstrate that PepThink-R1 generates cyclic peptides with significantly enhanced lipophilicity, stability, and exposure, outperforming existing general LLMs (e.g., GPT-5) and domain-specific baseline in both optimization success and interpretability. To our knowledge, this is the first LLM-based peptide design framework that combines explicit reasoning with RL-driven property control, marking a step toward reliable and transparent peptide optimization for therapeutic discovery.

cs.LG↗
arXiv2026

BrainCast: A Spatio-Temporal Forecasting Model for Whole-Brain fMRI Time Series Prediction

Functional magnetic resonance imaging (fMRI) enables noninvasive investigation of brain function, while short clinical scan durations, arising from human and non-human factors, usually lead to reduced data quality and limited statistical power for neuroimaging research. In this paper, we propose BrainCast, a novel spatio-temporal forecasting framework specifically tailored for whole-brain fMRI time series forecasting, to extend informative fMRI time series without additional data acquisition. It formulates fMRI time series forecasting as a multivariate time series prediction task and jointly models temporal dynamics within regions of interest (ROIs) and spatial interactions across ROIs. Specifically, BrainCast integrates a Spatial Interaction Awareness module to characterize inter-ROI dependencies via embedding every ROI time series as a token, a Temporal Feature Refinement module to capture intrinsic neural dynamics within each ROI by enhancing both low- and high-energy temporal components of fMRI time series at the ROI level, and a Spatio-temporal Pattern Alignment module to combine spatial and temporal representations for producing informative whole-brain features. Experimental results on resting-state and task fMRI datasets from the Human Connectome Project demonstrate the superiority of BrainCast over state-of-the-art time series forecasting baselines. Moreover, fMRI time series extended by BrainCast improve downstream cognitive ability prediction, highlighting the clinical and neuroscientific impact brought by whole-brain fMRI time series forecasting in scenarios with restricted scan durations.

cs.CV↗
arXiv2026

DDS-UDA: Dual-Domain Synergy for Unsupervised Domain Adaptation in Joint Segmentation of Optic Disc and Optic Cup

Convolutional neural networks (CNNs) have achieved exciting performance in joint segmentation of optic disc and optic cup on single-institution datasets. However, their clinical translation is hindered by two major challenges: limited availability of large-scale, high-quality annotations and performance degradation caused by domain shift during deployment across heterogeneous imaging protocols and acquisition platforms. While unsupervised domain adaptation (UDA) provides a way to mitigate these limitations, most existing approaches do not address cross-domain interference and intra-domain generalization within a unified framework. In this paper, we present the Dual-Domain Synergy UDA (DDS-UDA), a novel UDA framework that comprises two key modules. First, a bi-directional cross-domain consistency regularization module is enforced to mitigate cross-domain interference through feature-level semantic information exchange guided by a coarse-to-fine dynamic mask generator, suppressing noise propagation while preserving structural coherence. Second, a frequency-driven intra-domain pseudo label learning module is used to enhance intra-domain generalization by synthesizing spectral amplitude-mixed supervision signals, which ensures high-fidelity feature alignment across domains. Implemented within a teacher-student architecture, DDS-UDA disentangles domain-specific biases from domain-invariant feature-level representations, thereby achieving robust adaptation to heterogeneous imaging environments. We conduct a comprehensive evaluation of our proposed method on two multi-domain fundus image datasets, demonstrating that it outperforms several existing UDA based methods and therefore providing an effective way for optic disc and optic cup segmentation.

cs.CV↗
arXiv2026

FCN-LLM: Empower LLM for Brain Functional Connectivity Network Understanding via Graph-level Multi-task Instruction Tuning

Large Language Models have achieved remarkable success in language understanding and reasoning, and their multimodal extensions enable comprehension of images, video, and audio. Inspired by this, foundation models for brain functional connectivity networks derived from resting-state fMRI have shown promise in clinical tasks. However, existing methods do not align FCNs with the text modality, limiting the ability of LLMs to directly understand FCNs. To address this, we propose FCN-LLM, a framework that enables LLMs to understand FCNs through graph-level, multi-task instruction tuning. Our approach employs a multi-scale FCN encoder capturing brain-region, functional subnetwork, and whole-brain features, projecting them into the semantic space of LLM. We design multi-paradigm instruction tasks covering 19 subject-specific attributes across demographics, phenotypes, and psychiatric conditions. A multi-stage learning strategy first aligns FCN embeddings with the LLM and then jointly fine-tunes the entire model to capture high-level semantic information. Experiments on a large-scale, multi-site FCN database show that FCN-LLM achieves strong zero-shot generalization on unseen datasets, outperforming conventional supervised and foundation models. This work introduces a new paradigm for integrating brain functional networks with LLMs, offering a flexible and interpretable framework for neuroscience.

cs.AI↗
arXiv2026

AI-driven Large-scale Electron Microscopy enables Whole-tissue Subcellular Digitization

The distribution and interactions of cellular organelles play a critical role in mediating cellular physiology and pathology. Large-scale electron microscopy enables visualization of organelle distribution and interactions at the tissue level with nanometer resolution, but robust and efficient computational analysis tools are lacking. Here, we present a deep learning tool for universal large-scale 2D/3D electron microscopy analysis, DeepOrganelle. This new tool enables high-throughput, cell-resolved spatiotemporal mapping and digitization of organelle distribution and interactions. When applied to spermatogenesis across 12 stages and 22 differentiation status of the germ cells, DeepOrganelle uncovered previously unrecognized, stage-dependent dynamics of mitochondria-endoplasmic reticulum contact sites within one subphase of prophase I during meiosis. It also revealed coordinated organelle redistribution in Sertoli cells towards the blood-testis barrier, digitizing the remodeling dynamics of the tissue. This study demonstrates that DeepOrganelle provides a powerful framework that captures subcellular dynamics at the whole-tissue level.

physics.bio-ph↗
arXiv2026

ATPO: Adaptive Tree Policy Optimization for Multi-Turn Medical Dialogue

Effective information seeking in multi-turn medical dialogues is critical for accurate diagnosis, especially when dealing with incomplete information. Aligning Large Language Models (LLMs) for these interactive scenarios is challenging due to the uncertainty inherent in user-agent interactions, which we formulate as a Hierarchical Markov Decision Process (H-MDP). While conventional Reinforcement Learning (RL) methods like Group Relative Policy Optimization (GRPO) struggle with long-horizon credit assignment and Proximal Policy Optimization (PPO) suffers from unstable value estimation in this context, we propose a novel uncertainty-aware Adaptive Tree Policy Optimization (ATPO) algorithm. Our method adaptively allocates the rollout budget to states with high uncertainty, quantified by a composite metric of Bellman error and action-value variance. This strategy enables more accurate value estimation, while fostering more efficient and diverse exploration. To mitigate the high computational cost of tree-based RL, we introduce two key optimizations: an uncertainty-guided pruning mechanism to minimize the number of rollouts, and an asynchronous search architecture that leverages KV cache reuse to maximize inference throughput. Extensive experiments on three public medical dialogue benchmarks demonstrate that our algorithm significantly outperforms several strong baselines, culminating in Qwen3-8B model surpassing the much larger GPT-4o ($+0.92\%$ accuracy).

cs.LG↗
arXiv2026

ReGLA: Efficient Receptive-Field Modeling with Gated Linear Attention Network

Balancing accuracy and latency on high-resolution images is a critical challenge for lightweight models, particularly for Transformer-based architectures that often suffer from excessive latency. To address this issue, we introduce \textbf{ReGLA}, a series of lightweight hybrid networks, which integrates efficient convolutions for local feature extraction with ReLU-based gated linear attention for global modeling. The design incorporates three key innovations: the Efficient Large Receptive Field (ELRF) module for enhancing convolutional efficiency while preserving a large receptive field; the ReLU Gated Modulated Attention (RGMA) module for maintaining linear complexity while enhancing local feature representation; and a multi-teacher distillation strategy to boost performance on downstream tasks. Extensive experiments validate the superiority of ReGLA; particularly the ReGLA-M achieves \textbf{80.85\%} Top-1 accuracy on ImageNet-1K at $224px$, with only \textbf{4.98 ms} latency at $512px$. Furthermore, ReGLA outperforms similarly scaled iFormer models in downstream tasks, achieving gains of \textbf{3.1\%} AP on COCO object detection and \textbf{3.6\%} mIoU on ADE20K semantic segmentation, establishing it as a state-of-the-art solution for high-resolution visual applications.

cs.CV↗
arXiv2026

Impact of Phonetics on Speaker Identity in Adversarial Voice Attack

Adversarial perturbations in speech pose a serious threat to automatic speech recognition (ASR) and speaker verification by introducing subtle waveform modifications that remain imperceptible to humans but can significantly alter system outputs. While targeted attacks on end-to-end ASR models have been widely studied, the phonetic basis of these perturbations and their effect on speaker identity remain underexplored. In this work, we analyze adversarial audio at the phonetic level and show that perturbations exploit systematic confusions such as vowel centralization and consonant substitutions. These distortions not only mislead transcription but also degrade phonetic cues critical for speaker verification, leading to identity drift. Using DeepSpeech as our ASR target, we generate targeted adversarial examples and evaluate their impact on speaker embeddings across genuine and impostor samples. Results across 16 phonetically diverse target phrases demonstrate that adversarial audio induces both transcription errors and identity drift, highlighting the need for phonetic-aware defenses to ensure the robustness of ASR and speaker recognition systems.

cs.SD↗