arXiv subjects

Liangqiong Qu

Publications and source records attributed to Liangqiong Qu.

At least 19 recordsLinked to original sources

arXiv2026

A Vision-Language Foundation Model for Precise and Comprehensive Brain Tumor Diagnosis from Preoperative Multimodal Data

Background Non-invasive presurgical diagnosis of brain tumor types from Magnetic Resonance Imaging (MRI) is essential but challenging due to overlapping imaging features across tumor types, inter-observer variability, and the extensive training required for expertise. We aimed to develop an MRI-based Artificial Intelligence (AI) model for automatic and reliable brain tumor classification with diagnostic uncertainty quantification and radiology reports generation. Methods We developed BrainVLM to classify all 12 World Health Organization (WHO) 2021 brain tumor types. BrainVLM integrates an uncertainty quantification strategy to indicate prediction reliability and a module for generating radiology reports to elucidate the clinical rationale. BrainVLM was trained on multi-modal data (MRI scans, demographics, and radiology reports) from 40,043 individuals. It was validated on 5,211 patients with pathologically confirmed brain tumors, including 3,877 held-out patients from the primary hospital and 1,334 patients from 11 independent hospitals. We further conducted two proof-of-concept studies to validate its clinical utility in AI-clinician workflows: 1) a blinded multi-reader study where 12 neuroradiologists across varying experience levels interpreted 248 retrospective cases with or without AI assistance, and 2) a real-world prospective study in which 1,009 patients were independently and blindly assessed by BrainVLM and radiologists before surgery. Additionally, we demonstrated BrainVLM's utility in preoperative molecular subgroup prediction for adult-type diffuse gliomas, using a multi-center cohort of 632 patients.

cs.CV↗

arXiv2026

Discrete Diffusion Bridges for Spatiotemporally Aligned Image Translation and Generation

We propose Discrete Diffusion Bridges (DDB), a novel framework designed to resolve the fundamental spatiotemporal misalignment of standard discrete diffusion in image translation and generation. By corrupting data into a pure mask state via a random schedule, the conventional forward process induces a twofold misalignment: spatially, this pure-mask destination entirely discards the rich structural priors of the source image; temporally, the random masking order inherently contradicts the ``easy-first, hard-last'' decoding mechanism used during inference. To address this, DDB constructs a direct and efficient trajectory between domains. Spatially, we introduce a hybrid absorption mechanism that redefines the absorbing state to a stochastic mixture of mask and source tokens, effectively injecting source prior as spatial anchors into the latent space. Temporally, we design an information-guided noise schedule that quantifies semantic variation to prioritize the corruption of high-information regions at earlier timesteps. This ensures the model learns to resolve difficult semantic changes using robust context from invariant regions. Extensive experiments validate the versatility and robustness of our framework across diverse generative paradigms. DDB effectively balances edit alignment with structural fidelity across both text-guided semantic manipulation and pure structural image translation, while inherently complementing text-to-image generation and guaranteeing robust high-quality decoding under extremely low sampling steps. Code and models are available at \href{https://github.com/HKU-HealthAI/DDB}{https://github.com/HKU-HealthAI/DDB}.

cs.CV↗

arXiv2026

Agentic AI-powered flexible fiber-bundle endoscopy for high-resolution NIR-II fluorescence imaging in vivo

Fiber-bundle endoscopy offers a compact and flexible route for clinical fluorescence imaging through natural human orifices, but since its first report in the 1950s, it has remained limited by low spatial resolution, honeycomb artifacts, and inter-core crosstalk. The crosstalk becomes more pronounced at near-infrared-II wavelengths (NIR-II, 1000-3000 nm), a spectral window that offers superior contrast, resolution, and tissue penetration depth for biomedical imaging. Here, we present an AI-powered flexible endoscopy platform that overcomes these constraints through optical-computational co-design: optimizing ultrathin fiber bundles to mitigate crosstalk-induced image blur and enable high-fidelity image transmission across the visible-to-NIR-II spectral range, and developing an Agent-Guided Mixture-of-Experts (GAME) pipeline for honeycomb-artifact removal and image restoration. GAME provides a single restoration entry point for diverse biomedical images acquired with our endoscope, spanning cell, mouse and human samples. It dynamically routes each input to suitable restoration experts via a vision-language model, facilitating image reconstruction with a fourfold resolution improvement beyond the NyquistShannon sampling limit. The utility of our endoscope is demonstrated through in vivo NIR-II imaging of anatomical structures in mice, as well as imaging of the digital micromirror device (DMD)-projected human gastric tube and lymphatic system, paving the way for future clinical translation.

cs.CV↗

arXiv2026

Decoupled Residual Denoising Diffusion Models for Unified and Data Efficient Image-to-Image Translation

We propose Decoupled Residual Denoising Diffusion models (DRDD) for unified and data-efficient image-to-image (I2I) translation. While diffusion models have advanced I2I translation in terms of quality and diversity, we uncover a previously under-explored property in diffusion models. Crucially, beyond its conventional role of manifold lifting (i.e., moving data off low-dimensional manifolds), injecting Gaussian noise facilitates domain harmonization by implicitly aligning feature distributions across domains, a property particularly advantageous for unified I2I translation. However, existing diffusion models prematurely erode this harmonization effect, as noise and residuals are simultaneously removed in a single coupled diffusion process. To address this, DRDD decouples the diffusion process into two sequential and independent diffusion stages: (1) a stochastic noise diffusion for domain harmonization and manifold lifting, and (2) a deterministic residual diffusion that learns the core semantic mapping entirely within the fixed-noise domain. This decoupling preserves harmonization and manifold lifting effects throughout the transformation, substantially simplifying the learning of unified mappings across diverse tasks and domains. Notably, the noise diffusion stage is trained exclusively on abundant, unpaired target-domain images, greatly improving data efficiency. Comprehensive theoretical and empirical analysis demonstrates that DRDD is broadly compatible with mainstream diffusion models and consistently delivers robust, unified I2I translation, even under limited paired data. Our code is available at https://github.com/HKU-HealthAI/DRDD.

cs.CV↗

arXiv2026

Unveiling Implicit Advantage Symmetry: Why GRPO Struggles with Exploration and Difficulty Adaptation

Reinforcement Learning with Verifiable Rewards (RLVR), particularly GRPO, has become the standard for eliciting LLM reasoning. However, its efficiency in exploration and difficulty adaptation remains an open challenge. In this work, we argue that these bottlenecks stem from an implicit advantage symmetry inherent in Group Relative Advantage Estimation (GRAE). This symmetry induces two critical limitations: (i) at the group level, strict symmetry in weights between correct and incorrect trajectories leaves unsampled action logits unchanged, thereby hindering exploration of novel correct solution. (ii) at the sample level, the algorithm implicitly prioritizes medium-difficulty samples, remaining agnostic to the non-stationary demands of difficulty focus. Through controlled experiments, we reveal that this symmetric property is sub-optimal, yielding two pivotal insights: (i) asymmetrically suppressing the advantages of correct trajectories encourages essential exploration. (ii) learning efficiency is maximized by a curriculum-like transition-prioritizing simpler samples initially before gradually shifting to complex ones. Motivated by these findings, we propose Asymmetric GRAE (A-GRAE), which dynamically modulates exploration incentives and sample-difficulty focus. Experiments across seven benchmarks demonstrate that A-GRAE consistently improves GRPO and its variants across both LLMs and MLLMs.

cs.LG↗

arXiv2026

M-Gaussian: An Magnetic Gaussian Framework for Efficient Multi-Stack MRI Reconstruction

Magnetic Resonance Imaging (MRI) is a crucial non-invasive imaging modality. In routine clinical practice, multi-stack thick-slice acquisitions are widely used to reduce scan time and motion sensitivity, particularly in challenging scenarios such as fetal brain imaging. However, the resulting severe through-plane anisotropy compromises volumetric analysis and downstream quantitative assessment, necessitating robust reconstruction of isotropic high-resolution volumes. Implicit neural representation methods, while achieving high quality, suffer from computational inefficiency due to complex network structures. We present M-Gaussian, adapting 3D Gaussian Splatting to MRI reconstruction. Our contributions include: (1) Magnetic Gaussian primitives with physics-consistent volumetric rendering, (2) neural residual field for high-frequency detail refinement, and (3) multi-resolution progressive training. Our method achieves an optimal balance between quality and speed. On the FeTA dataset, M-Gaussian achieves 40.31 dB PSNR while being 14 times faster, representing the first successful adaptation of 3D Gaussian Splatting to multi-stack MRI reconstruction.

cs.CV↗

arXiv2026

DSKC: Domain Style Modeling with Adaptive Knowledge Consolidation for Exemplar-free Lifelong Person Re-Identification

Lifelong Person Re-identification (LReID) aims to continuously match individuals across camera views from sequential data streams. Existing LReID methods often ignore domain-specific style awareness and unified knowledge consolidation, which are crucial for mitigating forgetting when adapting to new information. We propose DSKC, a novel rehearsal-free and distillation-free framework for LReID. DSKC designs a domain-style encoder (DSE) to dynamically model domain-specific styles, and a unified knowledge consolidation (UKC) mechanism to adaptively integrate instance-level representations with domain-specific style into a cross-domain unified representation. By leveraging unified representation as a bridge, DSKC explicitly models inter-domain associations at both instance and domain levels to enhance anti-forgetting and generalization. Experimental results demonstrate that our DSKC outperforms state-of-the-art methods in two training orders and enhances the model's strong performance. Our code is available at https://github.com/LiuShiBen/DKUA.

cs.CV↗

arXiv2026

Exploring the Vulnerabilities of Federated Learning: A Deep Dive into Gradient Inversion Attacks

Federated Learning (FL) has emerged as a promising privacy-preserving collaborative model training paradigm without sharing raw data. However, recent studies have revealed that private information can still be leaked through shared gradient information and attacked by Gradient Inversion Attacks (GIA). While many GIA methods have been proposed, a detailed analysis, evaluation, and summary of these methods are still lacking. Although various survey papers summarize existing privacy attacks in FL, few studies have conducted extensive experiments to unveil the effectiveness of GIA and their associated limiting factors in this context. To fill this gap, we first undertake a systematic review of GIA and categorize existing methods into three types, i.e., \textit{optimization-based} GIA (OP-GIA), \textit{generation-based} GIA (GEN-GIA), and \textit{analytics-based} GIA (ANA-GIA). Then, we comprehensively analyze and evaluate the three types of GIA in FL, providing insights into the factors that influence their performance, practicality, and potential threats. Our findings indicate that OP-GIA is the most practical attack setting despite its unsatisfactory performance, while GEN-GIA has many dependencies and ANA-GIA is easily detectable, making them both impractical. Finally, we offer a three-stage defense pipeline to users when designing FL frameworks and protocols for better privacy protection and share some future research directions from the perspectives of attackers and defenders that we believe should be pursued. We hope that our study can help researchers design more robust FL frameworks to defend against these attacks.

cs.CR↗

arXiv2025

Unleashing the Potential of Large Language Models for Text-to-Image Generation through Autoregressive Representation Alignment

We present Autoregressive Representation Alignment (ARRA), a new training framework that unlocks global-coherent text-to-image generation in autoregressive LLMs without architectural modifications. Different from prior works that require complex architectural redesigns, ARRA aligns LLM's hidden states with visual representations from external visual foundational models via a global visual alignment loss and a hybrid token, . This token enforces dual constraints: local next-token prediction and global semantic distillation, enabling LLMs to implicitly learn spatial and contextual coherence while retaining their original autoregressive paradigm. Extensive experiments validate ARRA's plug-and-play versatility. When training T2I LLMs from scratch, ARRA reduces FID by 16.6% (ImageNet), 12.0% (LAION-COCO) for autoregressive LLMs like LlamaGen, without modifying original architecture and inference mechanism. For training from text-generation-only LLMs, ARRA reduces FID by 25.5% (MIMIC-CXR), 8.8% (DeepEyeNet) for advanced LLMs like Chameleon. For domain adaptation, ARRA aligns general-purpose LLMs with specialized models (e.g., BioMedCLIP), achieving an 18.6% FID reduction over direct fine-tuning on medical imaging (MIMIC-CXR). These results demonstrate that training objective redesign, rather than architectural modifications, can resolve cross-modal global coherence challenges. ARRA offers a complementary paradigm for advancing autoregressive models. The code is available at https://github.com/HKU-HealthAI/ARRA.

cs.CV↗

arXiv2025

Discrete Diffusion Models with MLLMs for Unified Medical Multimodal Generation

Recent advances in generative medical models are constrained by modality-specific scenarios that hinder the integration of complementary evidence from imaging, pathology, and clinical notes. This fragmentation limits their evolution into foundation models that can learn and reason across the full spectrum of biomedical data. We propose MeDiM, the first medical discrete diffusion model that learns shared distributions across modalities without modality-specific components. MeDiM unifies multiple generative tasks: translating between images and text, and jointly producing image-report pairs across domains in response to prompts. Built on a discrete diffusion framework, MeDiM bridges vision and language representations through a shared probabilistic space. To enable unified and flexible medical generation, we employ a multimodal large language model (MLLM) as the diffusion backbone, leveraging its prior knowledge and cross-modal reasoning. Two key designs are introduced: (1) removing the causal attention mask for bidirectional context, and (2) injecting continuous timestep embeddings for diffusion awareness. Experiments demonstrate high-fidelity medical generation (FID 16.60 on MIMIC-CXR and FID 24.19 on PathGen) and accurate report generation (METEOR 0.2650 and 0.2580). Jointly generated image-report pairs further enhance downstream performance (plus6.43 percent BLEU-1, plus18.57 percent BLEU-2, plus31.58 percent BLEU-3, plus4.80 percent METEOR), showing that MeDiM supports coherent and clinically grounded multimodal outputs.

cs.CV↗

arXiv2025

TextSplat: Text-Guided Semantic Fusion for Generalizable Gaussian Splatting

Recent advancements in Generalizable Gaussian Splatting have enabled robust 3D reconstruction from sparse input views by utilizing feed-forward Gaussian Splatting models, achieving superior cross-scene generalization. However, while many methods focus on geometric consistency, they often neglect the potential of text-driven guidance to enhance semantic understanding, which is crucial for accurately reconstructing fine-grained details in complex scenes. To address this limitation, we propose TextSplat--the first text-driven Generalizable Gaussian Splatting framework. By employing a text-guided fusion of diverse semantic cues, our framework learns robust cross-modal feature representations that improve the alignment of geometric and semantic information, producing high-fidelity 3D reconstructions. Specifically, our framework employs three parallel modules to obtain complementary representations: the Diffusion Prior Depth Estimator for accurate depth information, the Semantic Aware Segmentation Network for detailed semantic information, and the Multi-View Interaction Network for refined cross-view features. Then, in the Text-Guided Semantic Fusion Module, these representations are integrated via the text-guided and attention-based feature aggregation mechanism, resulting in enhanced 3D Gaussian parameters enriched with detailed semantic cues. Experimental results on various benchmark datasets demonstrate improved performance compared to existing methods across multiple evaluation metrics, validating the effectiveness of our framework. The code will be publicly available.

cs.CV↗

arXiv2025

StyleTailor: Towards Personalized Fashion Styling via Hierarchical Negative Feedback

The advancement of intelligent agents has revolutionized problem-solving across diverse domains, yet solutions for personalized fashion styling remain underexplored, which holds immense promise for promoting shopping experiences. In this work, we present StyleTailor, the first collaborative agent framework that seamlessly unifies personalized apparel design, shopping recommendation, virtual try-on, and systematic evaluation into a cohesive workflow. To this end, StyleTailor pioneers an iterative visual refinement paradigm driven by multi-level negative feedback, enabling adaptive and precise user alignment. Specifically, our framework features two core agents, i.e., Designer for personalized garment selection and Consultant for virtual try-on, whose outputs are progressively refined via hierarchical vision-language model feedback spanning individual items, complete outfits, and try-on efficacy. Counterexamples are aggregated into negative prompts, forming a closed-loop mechanism that enhances recommendation quality. To assess the performance, we introduce a comprehensive evaluation suite encompassing style consistency, visual quality, face similarity, and artistic appraisal. Extensive experiments demonstrate StyleTailor's superior performance in delivering personalized designs and recommendations, outperforming strong baselines without negative feedback and establishing a new benchmark for intelligent fashion systems.

cs.CV↗

arXiv2025

Distribution-aware Forgetting Compensation for Exemplar-Free Lifelong Person Re-identification

Lifelong Person Re-identification (LReID) suffers from a key challenge in preserving old knowledge while adapting to new information. The existing solutions include rehearsal-based and rehearsal-free methods to address this challenge. Rehearsal-based approaches rely on knowledge distillation, continuously accumulating forgetting during the distillation process. Rehearsal-free methods insufficiently learn the distribution of each domain, leading to forgetfulness over time. To solve these issues, we propose a novel Distribution-aware Forgetting Compensation (DAFC) model that explores cross-domain shared representation learning and domain-specific distribution integration without using old exemplars or knowledge distillation. We propose a Text-driven Prompt Aggregation (TPA) that utilizes text features to enrich prompt elements and guide the prompt model to learn fine-grained representations for each instance. This can enhance the differentiation of identity information and establish the foundation for domain distribution awareness. Then, Distribution-based Awareness and Integration (DAI) is designed to capture each domain-specific distribution by a dedicated expert network and adaptively consolidate them into a shared region in high-dimensional space. In this manner, DAI can consolidate and enhance cross-domain shared representation learning while alleviating catastrophic forgetting. Furthermore, we develop a Knowledge Consolidation Mechanism (KCM) that comprises instance-level discrimination and cross-domain consistency alignment strategies to facilitate model adaptive learning of new knowledge from the current domain and promote knowledge consolidation learning between acquired domain-specific distributions, respectively. Experimental results show that our DAFC outperforms state-of-the-art methods. Our code is available at https://github.com/LiuShiBen/DAFC.

cs.CV↗

arXiv2025

ATSTrack: Enhancing Visual-Language Tracking by Aligning Temporal and Spatial Scales

A main challenge of Visual-Language Tracking (VLT) is the misalignment between visual inputs and language descriptions caused by target movement. Previous trackers have explored many effective feature modification methods to preserve more aligned features. However, an important yet unexplored factor ultimately hinders their capability, which is the inherent differences in the temporal and spatial scale of information between visual and language inputs. To address this issue, we propose a novel visual-language tracker that enhances the effect of feature modification by \textbf{A}ligning \textbf{T}emporal and \textbf{S}patial scale of different input components, named as \textbf{ATSTrack}. Specifically, we decompose each language description into phrases with different attributes based on their temporal and spatial correspondence with visual inputs, and modify their features in a fine-grained manner. Moreover, we introduce a Visual-Language token that comprises modified linguistic information from the previous frame to guide the model to extract visual features that are more relevant to language description, thereby reducing the impact caused by the differences in spatial scale. Experimental results show that our proposed ATSTrack achieves performance comparable to existing methods. Our code will be released.

cs.CV↗

arXiv2025

HSENet: Hybrid Spatial Encoding Network for 3D Medical Vision-Language Understanding

Automated 3D CT diagnosis empowers clinicians to make timely, evidence-based decisions by enhancing diagnostic accuracy and workflow efficiency. While multimodal large language models (MLLMs) exhibit promising performance in visual-language understanding, existing methods mainly focus on 2D medical images, which fundamentally limits their ability to capture complex 3D anatomical structures. This limitation often leads to misinterpretation of subtle pathologies and causes diagnostic hallucinations. In this paper, we present Hybrid Spatial Encoding Network (HSENet), a framework that exploits enriched 3D medical visual cues by effective visual perception and projection for accurate and robust vision-language understanding. Specifically, HSENet employs dual-3D vision encoders to perceive both global volumetric contexts and fine-grained anatomical details, which are pre-trained by dual-stage alignment with diagnostic reports. Furthermore, we propose Spatial Packer, an efficient multimodal projector that condenses high-resolution 3D spatial regions into a compact set of informative visual tokens via centroid-based compression. By assigning spatial packers with dual-3D vision encoders, HSENet can seamlessly perceive and transfer hybrid visual representations to LLM's semantic space, facilitating accurate diagnostic text generation. Experimental results demonstrate that our method achieves state-of-the-art performance in 3D language-visual retrieval (39.85% of R@100, +5.96% gain), 3D medical report generation (24.01% of BLEU-4, +8.01% gain), and 3D visual question answering (73.60% of Major Class Accuracy, +1.99% gain), confirming its effectiveness. Our code is available at https://github.com/YanzhaoShi/HSENet.

cs.CV↗

arXiv2025

FedVLMBench: Benchmarking Federated Fine-Tuning of Vision-Language Models

Vision-Language Models (VLMs) have demonstrated remarkable capabilities in cross-modal understanding and generation by integrating visual and textual information. While instruction tuning and parameter-efficient fine-tuning methods have substantially improved the generalization of VLMs, most existing approaches rely on centralized training, posing challenges for deployment in domains with strict privacy requirements like healthcare. Recent efforts have introduced Federated Learning (FL) into VLM fine-tuning to address these privacy concerns, yet comprehensive benchmarks for evaluating federated fine-tuning strategies, model architectures, and task generalization remain lacking. In this work, we present \textbf{FedVLMBench}, the first systematic benchmark for federated fine-tuning of VLMs. FedVLMBench integrates two mainstream VLM architectures (encoder-based and encoder-free), four fine-tuning strategies, five FL algorithms, six multimodal datasets spanning four cross-domain single-task scenarios and two cross-domain multitask settings, covering four distinct downstream task categories. Through extensive experiments, we uncover key insights into the interplay between VLM architectures, fine-tuning strategies, data heterogeneity, and multi-task federated optimization. Notably, we find that a 2-layer multilayer perceptron (MLP) connector with concurrent connector and LLM tuning emerges as the optimal configuration for encoder-based VLMs in FL. Furthermore, current FL methods exhibit significantly higher sensitivity to data heterogeneity in vision-centric tasks than text-centric ones, across both encoder-free and encoder-based VLM architectures. Our benchmark provides essential tools, datasets, and empirical guidance for the research community, offering a standardized platform to advance privacy-preserving, federated training of multimodal foundation models.

cs.LG↗

arXiv2025

Exploring Federated Pruning for Large Language Models

LLM pruning has emerged as a promising technology for compressing LLMs, enabling their deployment on resource-limited devices. However, current methodologies typically require access to public calibration samples, which can be challenging to obtain in privacy-sensitive domains. To address this issue, we introduce FedPrLLM, a comprehensive federated pruning framework designed for the privacy-preserving compression of LLMs. In FedPrLLM, each client only needs to calculate a pruning mask matrix based on its local calibration data and share it with the server to prune the global model. This approach allows for collaborative pruning of the global model with the knowledge of each client while maintaining local data privacy. Additionally, we conduct extensive experiments to explore various possibilities within the FedPrLLM framework, including different comparison groups, pruning strategies, and the decision to scale weights. Our extensive evaluation reveals that one-shot pruning with layer comparison and no weight scaling is the optimal choice within the FedPrLLM framework. We hope our work will help guide future efforts in pruning LLMs in privacy-sensitive fields. Our code is available at https://github.com/Pengxin-Guo/FedPrLLM.

cs.LG↗

arXiv2025

MEPNet: Medical Entity-balanced Prompting Network for Brain CT Report Generation

The automatic generation of brain CT reports has gained widespread attention, given its potential to assist radiologists in diagnosing cranial diseases. However, brain CT scans involve extensive medical entities, such as diverse anatomy regions and lesions, exhibiting highly inconsistent spatial patterns in 3D volumetric space. This leads to biased learning of medical entities in existing methods, resulting in repetitiveness and inaccuracy in generated reports. To this end, we propose a Medical Entity-balanced Prompting Network (MEPNet), which harnesses the large language model (LLM) to fairly interpret various entities for accurate brain CT report generation. By introducing the visual embedding and the learning status of medical entities as enriched clues, our method prompts the LLM to balance the learning of diverse entities, thereby enhancing reports with comprehensive findings. First, to extract visual embedding of entities, we propose Knowledge-driven Joint Attention to explore and distill entity patterns using both explicit and implicit medical knowledge. Then, a Learning Status Scorer is designed to evaluate the learning of entity visual embeddings, resulting in unique learning status for individual entities. Finally, these entity visual embeddings and status are elaborately integrated into multi-modal prompts, to guide the text generation of LLM. This process allows LLM to self-adapt the learning process for biased-fitted entities, thereby covering detailed findings in generated reports. We conduct experiments on two brain CT report generation benchmarks, showing the effectiveness in clinical accuracy and text coherence.

cs.AI↗