arXiv subjects

Libo Wu

Publications and source records attributed to Libo Wu.

15 recordsLinked to original sources

arXiv2026

Unfolding the Interdisciplinary Complexities of Climate Science: Fuxi-Climate Foundational Model

Climate research and decision-making require integrating evidence across physical processes, socio-economic dynamics and policy responses. Large language models (LLMs) have been explored for accessing and synthesizing climate knowledge, but their ability to support structured interdisciplinary reasoning is still limited. Here we present the Fuxi-Climate Foundation Model (CFM), a climate-specialized LLM designed to support consistent reasoning across domains. CFM maintains more stable analytical behavior as interdisciplinary complexity increases, whereas performance in other models becomes more variable. On expert-designed climate transition tasks, CFM produces more structured analyses that explicitly address trade-offs and uncertainty, achieving 45% trade-off coverage and 47.27% uncertainty-aware reasoning. These results indicate that CFM can support more realistic analysis of climate risks and transition pathways, and provide a basis for agent-based systems to explore complex policy and decision scenarios. The model is openly available at https://huggingface.co/SII-yuning/cfm.

cs.CY↗

arXiv2026

Monkey King Bang: A Unified Scientific Multimodal Foundation Model

Scientific discovery is increasingly shifting from isolated disciplines to multi-domain reasoning, and AI for science faces a similar transition. Existing systems are either specialised for individual domains or unify scientific data mainly through text tokenisation and prompt-based interfaces, limiting their ability to handle diverse scientific inputs, produce modality-native outputs, and support joint understanding, reasoning, and generation across scientific domains. We introduce MKB, a unified scientific multimodal model for both understanding and generation, built around a shared Transformer backbone and modality-tailored encoders, adapters, and decoders. MKB covers six scientific branches, including DNA, RNA, proteins, small molecules, earth science, and medical images, and supports native outputs such as biological sequences, molecular strings, meteorological fields, and segmentation masks. Training follows a two-stage modality-then-language curriculum: Stage 1 aligns modality-specific components with the frozen backbone, and Stage 2 consolidates them with the language backbone using mixed scientific and general corpora. Experiments show that MKB achieves competitive scientific understanding across biological and molecular benchmarks, produces high-fidelity native outputs for weather forecasting, biological generation, and medical-image segmentation, and largely retains the general capabilities of its Qwen3-VL backbone. These results demonstrate the feasibility of the proposed paradigm, suggesting that shared-backbone models with modality-tailored components can provide a promising foundation for future cross-domain scientific multimodal exploration. The model and code are publicly available at https://github.com/Shanghai-Academy-of-AI-For-Science/MKB and https://huggingface.co/sais-org/MKB.

cs.LG↗

arXiv2026

DyneTrion: A Spatio-temporally Coherent Generative Emulator for Protein Dynamics Across Timescales

Proteins function through coordinated motion across multiple spatial and temporal scales, underpinning processes such as ligand binding, allostery, and catalysis. However, accessing long-timescale conformational change through molecular dynamics (MD) simulations remains prohibitively expensive for systematic exploration across diverse systems. Here, we present DyneTrion, a generative protein dynamics emulator that jointly enforces geometric symmetry, structural consistency and temporal coherence within a single framework. DyneTrion uses a tri-attention architecture that integrates invariant point attention (IPA) for SE(3)-robust geometric updates, spatial attention anchored to a reference conformation to preserve structural integrity, and temporal attention to model correlated evolution across time frames. Across 100-ns MD trajectory simulation benchmarks, DyneTrion reproduces MD-derived flexibility, ensemble distributions and interaction observables while maintaining stereochemical validity during extrapolation. To evaluate long time-scale generalization, we introduce dynamicPDB, a dataset of over 10,000 proteins with up to 1-$\mu$s all-atom trajectories at 10-ps resolution and accompanying physical annotations. On microsecond trajectories, DyneTrion preserves free-energy landscapes and metastable-state populations, and it supports large conformational propagation in apo-to-holo transitions and fast folders. Together, DyneTrion provides a scalable path from static structure prediction toward time-resolved, ensemble-faithful protein modeling. The code is publicly available at https://github.com/fudan-generative-vision/DyneTrion

q-bio.QM↗

arXiv2026

InterveneBench: Benchmarking LLMs for Intervention Reasoning and Causal Study Design in Real Social Systems

Causal inference in social science relies on end-to-end, intervention-centered research-design reasoning grounded in real-world policy interventions, but current benchmarks fail to evaluate this capability of large language models (LLMs). We present InterveneBench, a benchmark designed to assess such reasoning in realistic social settings. Each instance in InterveneBench is derived from an empirical social science study and requires models to reason about policy interventions and identification assumptions without access to predefined causal graphs or structural equations. InterveneBench comprises 744 peer-reviewed studies across diverse policy domains. Experimental results show that state-of-the-art LLMs struggle under this setting. To address this limitation, we further propose a multi-agent framework, STRIDES. It achieves significant performance improvements over state-of-the-art reasoning models. Our code and data are available at https://github.com/Sii-yuning/STRIDES.

cs.CY↗

arXiv2026

Zero-Shot Statistical Downscaling via Diffusion Posterior Sampling

Conventional supervised climate downscaling struggles to generalize to Global Climate Models (GCMs) due to the lack of paired training data and inherent domain gaps relative to reanalysis. Meanwhile, current zero-shot methods suffer from physical inconsistencies and vanishing gradient issues under large scaling factors. We propose Zero-Shot Statistical Downscaling (ZSSD), a zero-shot framework that performs statistical downscaling without paired data during training. ZSSD leverages a Physics-Consistent Climate Prior learned from reanalysis data, conditioned on geophysical boundaries and temporal information to enforce physical validity. Furthermore, to enable robust inference across varying GCMs, we introduce Unified Coordinate Guidance. This strategy addresses the vanishing gradient problem in vanilla DPS and ensures consistency with large-scale fields. Results show that ZSSD significantly outperforms existing zero-shot baselines in 99th percentile errors and successfully reconstructs complex weather events, such as tropical cyclones, across heterogeneous GCMs.

cs.AI↗

arXiv2026

A unified multimodal understanding and generation model for cross-disciplinary scientific research

Scientific discovery increasingly relies on integrating heterogeneous, high-dimensional data across disciplines nowadays. While AI models have achieved notable success across various scientific domains, they typically remain domain-specific or lack the capability of simultaneously understanding and generating multimodal scientific data, particularly for high-dimensional data. Yet, many pressing global challenges and scientific problems are inherently cross-disciplinary and require coordinated progress across multiple fields. Here, we present FuXi-Uni, a native unified multimodal model for scientific understanding and high-fidelity generation across scientific domains within a single architecture. Specifically, FuXi-Uni aligns cross-disciplinary scientific tokens within natural language tokens and employs science decoder to reconstruct scientific tokens, thereby supporting both natural language conversation and scientific numerical prediction. Empirically, we validate FuXi-Uni in Earth science and Biomedicine. In Earth system modeling, the model supports global weather forecasting, tropical cyclone (TC) forecast editing, and spatial downscaling driven by only language instructions. FuXi-Uni generates 10-day global forecasts at 0.25{\deg} resolution that outperform the SOTA physical forecasting system. It shows superior performance for both TC track and intensity prediction relative to the SOTA physical model, and generates high-resolution regional weather fields that surpass standard interpolation baselines. Regarding biomedicine, FuXi-Uni outperforms leading multimodal large language models on multiple biomedical visual question answering benchmarks. By unifying heterogeneous scientific modalities within a native shared latent space while maintaining strong domain-specific performance, FuXi-Uni provides a step forward more general-purpose, multimodal scientific models.

cs.AI↗

arXiv2025

Crystal Eye: all sky MeV monitor with high precision real-time localization

Crystal Eye is a space-based all-sky monitor optimized for the autonomous detection and localization of transients in the 10 keV to 30 MeV energy range, a region where extensive observations and monitoring of various astrophysical phenomena are required. By focusing on the operating environment and its impact on the observation process, we optimized the detector design and assessed its scientific potential. We explored the use of novel techniques to achieve the science goals of the experiment. We assumed the orbit of a potential future mission at approximately 550 km altitude near the equatorial region with a 20{\deg} inclination. In such an orbit, the main background contributions for this kind of detector are from different particles and radiation of cosmic origin and secondaries produced by their interaction in the Earth's atmospheric and geomagnetic environment. We studied the response of the detector in this background environment, using the Geant4 Monte Carlo simulation toolkit. We also calculated other detector performance parameters to estimate its scientific capabilities. The detector effective area and efficiency are calculated for low energy gamma-ray sources and used to estimate its sensitivity to short-duration transient sources. The calculation shows a better effective area and sensitivity by several factors compared to existing instruments of similar type. A method is also developed and discussed to estimate the online transient-localization performance of the detector, suggesting a better localization precision by about an order of magnitude than those typically reported by existing gamma-ray monitors. We present here the simulation study and results of an innovative detector design concept that can make a significant contribution in the multi-messenger era. Moreover, this study can be useful as a technical reference for similar future experiments.

astro-ph.IM↗

arXiv2025

FuXi-Air: Urban Air Quality Forecasting Based on Emission-Meteorology-Pollutant multimodal Machine Learning

Air pollution has emerged as a major public health challenge in megacities. Numerical simulations and single-site machine learning approaches have been widely applied in air quality forecasting tasks. However, these methods face multiple limitations, including high computational costs, low operational efficiency, and limited integration with observational data. With the rapid advancement of artificial intelligence, there is an urgent need to develop a low-cost, efficient air quality forecasting model for smart urban management. An air quality forecasting model, named FuXi-Air, has been constructed in this study based on multimodal data fusion to support high-precision air quality forecasting and operated in typical megacities. The model integrates meteorological forecasts, emission inventories, and pollutant monitoring data under the guidance of air pollution mechanism. By combining an autoregressive prediction framework with a frame interpolation strategy, the model successfully completes 72-hour forecasts for six major air pollutants at an hourly resolution across multiple monitoring sites within 25-30 seconds. In terms of both computational efficiency and forecasting accuracy, it outperforms the mainstream numerical air quality models in operational forecasting work. Ablation experiments concerning key influencing factors show that although meteorological data contribute more to model accuracy than emission inventories do, the integration of multimodal data significantly improves forecasting precision and ensures that reliable predictions are obtained under differing pollution mechanisms across megacities. This study provides both a technical reference and a practical example for applying multimodal data-driven models to air quality forecasting and offers new insights into building hybrid forecasting systems to support air pollution risk warning in smart city management.

cs.LG↗

arXiv2025

A machine learning model for skillful climate system prediction

Climate system models (CSMs), through integrating cross-sphere interactions among the atmosphere, ocean, land, and cryosphere, have emerged as pivotal tools for deciphering climate dynamics and improving forecasting capabilities. Recent breakthroughs in artificial intelligence (AI)-driven meteorological modeling have demonstrated remarkable success in single-sphere systems and partially spheres coupled systems. However, the development of a fully coupled AI-based climate system model encompassing atmosphere-ocean-land-sea ice interactions has remained an unresolved challenge. This paper introduces FengShun-CSM, an AI-based CSM model that provides 60-day global daily forecasts for 29 critical variables across atmospheric, oceanic, terrestrial, and cryospheric domains. The model significantly outperforms the European Centre for Medium-Range Weather Forecasts (ECMWF) subseasonal-to-seasonal (S2S) model in predicting most variables, particularly precipitation, land surface, and oceanic components. This enhanced capability is primarily attributed to its improved representation of intra-seasonal variability modes, most notably the Madden-Julian Oscillation (MJO). Remarkably, FengShun-CSM exhibits substantial potential in predicting subseasonal extreme events. Such breakthroughs will advance its applications in meteorological disaster mitigation, marine ecosystem conservation, and agricultural productivity enhancement. Furthermore, it validates the feasibility of developing AI-powered CSMs through machine learning technologies, establishing a transformative paradigm for next-generation Earth system modeling.

cs.LG↗

arXiv2025

SocioVerse: A World Model for Social Simulation Powered by LLM Agents and A Pool of 10 Million Real-World Users

Social simulation is transforming traditional social science research by modeling human behavior through interactions between virtual individuals and their environments. With recent advances in large language models (LLMs), this approach has shown growing potential in capturing individual differences and predicting group behaviors. However, existing methods face alignment challenges related to the environment, target users, interaction mechanisms, and behavioral patterns. To this end, we introduce SocioVerse, an LLM-agent-driven world model for social simulation. Our framework features four powerful alignment components and a user pool of 10 million real individuals. To validate its effectiveness, we conducted large-scale simulation experiments across three distinct domains: politics, news, and economics. Results demonstrate that SocioVerse can reflect large-scale population dynamics while ensuring diversity, credibility, and representativeness through standardized procedures and minimal manual adjustments.

cs.CL↗

arXiv2024

FuXi Weather: A data-to-forecast machine learning system for global weather

Weather forecasting traditionally relies on numerical weather prediction (NWP) systems that integrates global observational systems, data assimilation (DA), and forecasting models. Despite steady improvements in forecast accuracy over recent decades, further advances are increasingly constrained by high computational costs, the underutilization of vast observational datasets, and the challenges of obtaining finer resolution. These limitations, alongside the uneven distribution of observational networks, result in global disparities in forecast accuracy, leaving some regions vulnerable to extreme weather. Recent advances in machine learning present a promising alternative, providing more efficient and accurate forecasts using the same initial conditions as NWP. However, current machine learning models still depend on the initial conditions generated by NWP systems, which require extensive computational resources and expertise. Here we introduce FuXi Weather, a machine learning weather forecasting system that assimilates data from multiple satellites. Operating on a 6-hourly DA and forecast cycle, FuXi Weather generates reliable and accurate 10-day global weather forecasts at a spatial resolution of $0.25^\circ$. FuXi Weather is the first system to achieve all-grid, all-surface, all-channel, and all-sky DA and forecasting, extending skillful forecast lead times beyond those of the European Centre for Medium-range Weather Forecasts (ECMWF) high-resolution forecasts (HRES) while using significantly fewer observations. FuXi Weather consistently outperforms ECMWF HRES in observation-sparse regions, such as central Africa, demonstrating its potential to improve forecasts where observational infrastructure is limited.

cs.LG↗

arXiv2021

Inferring Economic Condition Uncertainty from Electricity Big Data

Inferring the uncertainty in economic conditions is significant for both decision makers as well as market players. In this paper, we propose a novel approach to measure the economic uncertainties by using the Hidden Markov Model (HMM). We construct a dimensionless index, Economic Condition Uncertainty (ECU) index, which ranges from zero to one and is comparable among sectors, regions and periods. We used the daily electricity consumption data of more than 18,000 firms in Shanghai from 2018 to 2020 to construct the ECU indexes. Results show that all ECU indexes, whether at sectoral or regional level, successfully captured the negative impacts of COVID-19 on Shanghai's economic conditions. Besides, the ECU indexes also presented the heterogeneities in different districts as well as in different sectors. This reflects the facts that changes in the uncertainty of economic conditions are mainly related to regional economic structures and targeted regulatory policies faced by sectors. The ECU index can also be readily extended to measure the uncertainty of economic conditions in various realms, which has great potentials in the future.

econ.GN↗

arXiv2020

Energy correction based on fluorescence attenuation of DAMPE

The major scientific goals of DArk Matter Particle Explorer (DAMPE) are to study cosmic-ray electrons (including positrons) and gamma rays from 5 GeV to 10 TeV and nuclei from Z = 1 to 26 up to 100 TeV. The deposited energy measured by the Bismuth Germanate Oxide (BGO) calorimeter of DAMPE is affected by fluorescence attenuation in BGO crystals that are 600 mm long. In this work, an in-orbit attenuation calibration method is reported, and energy correction of the sensitive detector unit of the BGO calorimeter is also presented.

physics.ins-det↗

arXiv2019

Calibration and Status of the 3D Imaging Calorimeter of DAMPE for Cosmic Ray Physics on Orbit

The DArk Matter Particle Explorer (DAMPE) developed in China was designed to search for evidence of dark matter particles by observing primary cosmic rays and gamma rays in the energy range from 5 GeV to 10 TeV. Since its launch in December 2015, a large quantity of data has been recorded. With the data set acquired during more than a year of operation in space, a precise time-dependent calibration for the energy measured by the BGO ECAL has been developed. In this report, the instrumentation and development of the BGO Electromagnetic Calorimeter (BGO ECAL) are briefly described. The calibration on orbit, including that of the pedestal, attenuation length, minimum ionizing particle peak, and dynode ratio, is discussed, and additional details about the calibration methods and performance in space are presented.

astro-ph.IM↗

arXiv2017

The $k$-tuple Prime Difference Champion

Let $D_{k}$ be a set with $k$ distinct elements of integers such that $d_{1}<d_{2}<\cdots<d_{k}$. We say $D_{k}^{*}$ is a $k$-tuple prime difference champion ($k$-tuple PDC) for primes $\le x$ if the set $D_{k}^{*}$ is the most probable differences among $k+1$ primes up to $x$. Unconditionally we prove that the $k$-tuple PDCs go to infinity and further have asymptotically the same number prime factors when weighted by logarithmic derivative as the porimorials. Assuming an appropriate form of the Hardy-Littlewood Prime $k$-tuple Conjecture, we obtain that the $k$-tuple PDCs are infinite square-free numbers containing any large primorial as factor when $x\rightarrow \infty$.

math.NT↗