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Liesbet M. Peeters

Publications and source records attributed to Liesbet M. Peeters.

5 recordsLinked to original sources

Development and Design of FLKit: A Structured Onboarding Toolkit for Federated Learning in Health and Life Sciences

Federated learning lets institutions train shared models without moving their data, which makes it a natural fit for health and life sciences research under strict privacy regulation. The methods are maturing fast, but the practical barrier now comes earlier: a team starting a federated project meets a scattered mix of frameworks, governance obligations, and unfamiliar roles, with no structured place to begin that fits its own background. FLKit closes that gap. It is an open, community-maintained onboarding toolkit that takes a multidisciplinary team through the full federated learning lifecycle and gives every contributor, clinical, legal, governance, or technical, a role-aware entry point instead of assuming fluency across all four. We modeled it on the ELIXIR Research Data Management Kit and built it with a multidisciplinary core team, a wider consortium supplying milestone reviews and roadmap direction, and external practitioners interviewed to keep the content grounded in real practice. FLKit sits on four lifecycle stages, Governance, Infrastructure, Wrangling, and Analysis, and connects them through 11 role-specific entry points, a cross-disciplinary glossary, a reusable FAIR-aligned FL Story template for planning and documenting projects, and a curated directory of tools, frameworks, and communities. Since the December 2024 demo it has grown to 39 pages across eight sections, with seven FL Stories documenting completed and ongoing projects in multiple sclerosis disability prediction, inflammatory bowel disease, genomics, and brain-computer interfaces. It is openly available at https://uhasselt-biomedicaldatasciences.github.io/federated-learning-toolkit/ and welcomes contributions from across the life sciences.

cs.DC↗

An Algorithmic Pipeline for GDPR-Compliant Healthcare Data Anonymisation: Moving Toward Standardisation

High-quality real-world data (RWD) is essential for healthcare but must be transformed to comply with the General Data Protection Regulation (GDPR). GDPRs broad definitions of quasi-identifiers (QIDs) and sensitive attributes (SAs) complicate implementation. We aim to standardise RWD anonymisation for GDPR compliance while preserving data utility by introducing an algorithmic method to identify QIDs and SAs and evaluate utility in anonymised datasets. We conducted a systematic literature review via ProQuest and PubMed to inform a three-stage anonymisation pipeline: identification, de-identification, and quasi-identifier dimension evaluation. The pipeline was implemented, validated, and tested on two mock RWD datasets (500 and 1000 rows). Privacy was assessed using k-anonymity, l-diversity, and t-closeness; utility was measured by non-uniform entropy (NUE). The review yielded two studies on QID/SA identification and five on utility metrics. Applying the pipeline, attributes were classified by re-identification risk using alpha and beta thresholds (25 percent/1 percent for 500 rows; 10 percent/1 percent for 1000 rows). Privacy metrics improved k-anonymity from 1 to 4 (500 rows) and 1 to 110 (1000 rows). NUE scores were 69.26 percent and 69.05 percent, respectively, indicating consistent utility despite varying privacy gains. We present a GDPR-compliant anonymisation pipeline for healthcare RWD that provides a reproducible approach to QID/SA identification and utility evaluation; publicly available code promotes standardisation, data privacy, and open science.

cs.CR↗

Federated Block-Term Tensor Regression for decentralised data analysis in healthcare

Block-Term Tensor Regression (BTTR) has proven to be a powerful tool for modeling complex, high-dimensional data by leveraging multilinear relationships, making it particularly well-suited for applications in healthcare and neuroscience. However, traditional implementations of BTTR rely on centralized datasets, which pose significant privacy risks and hinder collaboration across institutions. To address these challenges, we introduce Federated Block-Term Tensor Regression (FBTTR), an extension of BTTR designed for federated learning scenarios. FBTTR enables decentralized data analysis, allowing institutions to collaboratively build predictive models while preserving data privacy and complying with regulations. FBTTR represents a major step forward in applying tensor regression to federated learning environments. Its performance is evaluated in two case studies: finger movement decoding from Electrocorticography (ECoG) signals and heart disease prediction. In the first case study, using the BCI Competition IV dataset, FBTTR outperforms non-multilinear models, demonstrating superior accuracy in decoding finger movements. For the dataset, for subject 3, the thumb obtained a performance of 0.76 $\pm$ .05 compared to 0.71 $\pm$ 0.05 for centralised BTTR. In the second case study, FBTTR is applied to predict heart disease using real-world clinical datasets, outperforming both standard federated learning approaches and centralized BTTR models. In the Fed-Heart-Disease Dataset, an AUC-ROC was obtained of 0.872 $\pm$ 0.02 and an accuracy of 0.772 $\pm$ 0.02 compared to 0.812 $\pm$ 0.003 and 0.753 $\pm$ 0.007 for the centralized model.

cs.LG↗

Schema Matching with Large Language Models: an Experimental Study

Large Language Models (LLMs) have shown useful applications in a variety of tasks, including data wrangling. In this paper, we investigate the use of an off-the-shelf LLM for schema matching. Our objective is to identify semantic correspondences between elements of two relational schemas using only names and descriptions. Using a newly created benchmark from the health domain, we propose different so-called task scopes. These are methods for prompting the LLM to do schema matching, which vary in the amount of context information contained in the prompt. Using these task scopes we compare LLM-based schema matching against a string similarity baseline, investigating matching quality, verification effort, decisiveness, and complementarity of the approaches. We find that matching quality suffers from a lack of context information, but also from providing too much context information. In general, using newer LLM versions increases decisiveness. We identify task scopes that have acceptable verification effort and succeed in identifying a significant number of true semantic matches. Our study shows that LLMs have potential in bootstrapping the schema matching process and are able to assist data engineers in speeding up this task solely based on schema element names and descriptions without the need for data instances.

cs.DB↗

Measuring Approximate Functional Dependencies: a Comparative Study

Approximate functional dependencies (AFDs) are functional dependencies (FDs) that "almost" hold in a relation. While various measures have been proposed to quantify the level to which an FD holds approximately, they are difficult to compare and it is unclear which measure is preferable when one needs to discover FDs in real-world data, i.e., data that only approximately satisfies the FD. In response, this paper formally and qualitatively compares AFD measures. We obtain a formal comparison through a novel presentation of measures in terms of Shannon and logical entropy. Qualitatively, we perform a sensitivity analysis w.r.t. structural properties of input relations and quantitatively study the effectiveness of AFD measures for ranking AFDs on real world data. Based on this analysis, we give clear recommendations for the AFD measures to use in practice.

cs.DB↗