Lihua Lei — Page 4 | Searcharxiv

arXiv2016

Asymptotics For High Dimensional Regression M-Estimates: Fixed Design Results

We investigate the asymptotic distributions of coordinates of regression M-estimates in the moderate $p/n$ regime, where the number of covariates $p$ grows proportionally with the sample size $n$. Under appropriate regularity conditions, we establish the coordinate-wise asymptotic normality of regression M-estimates assuming a fixed-design matrix. Our proof is based on the second-order Poincaré inequality (Chatterjee, 2009) and leave-one-out analysis (El Karoui et al., 2011). Some relevant examples are indicated to show that our regularity conditions are satisfied by a broad class of design matrices. We also show a counterexample, namely the ANOVA-type design, to emphasize that the technical assumptions are not just artifacts of the proof. Finally, the numerical experiments confirm and complement our theoretical results.

math.ST↗

arXiv2016

Power of Ordered Hypothesis Testing

Ordered testing procedures are multiple testing procedures that exploit a pre-specified ordering of the null hypotheses, from most to least promising. We analyze and compare the power of several recent proposals using the asymptotic framework of Li & Barber (2015). While accumulation tests including ForwardStop can be quite powerful when the ordering is very informative, they are asymptotically powerless when the ordering is weaker. By contrast, Selective SeqStep, proposed by Barber & Candès (2015), is much less sensitive to the quality of the ordering. We compare the power of these procedures in different régimes, concluding that Selective SeqStep dominates accumulation tests if either the ordering is weak or non-null hypotheses are sparse or weak. Motivated by our asymptotic analysis, we derive an improved version of Selective SeqStep which we call Adaptive SeqStep, analogous to Storey's improvement on the Benjamini-Hochberg procedure. We compare these methods using the GEOQuery data set analyzed by Li & Barber (2015) and find Adaptive SeqStep has favorable performance for both good and bad prior orderings.

stat.ME↗