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Lin Wu

Publications and source records attributed to Lin Wu.

At least 91 records · Page 5Linked to original sources

Medi-Care AI: Predicting Medications From Billing Codes via Robust Recurrent Neural Networks

In this paper, we present an effective deep prediction framework based on robust recurrent neural networks (RNNs) to predict the likely therapeutic classes of medications a patient is taking, given a sequence of diagnostic billing codes in their record. Accurately capturing the list of medications currently taken by a given patient is extremely challenging due to undefined errors and omissions. We present a general robust framework that explicitly models the possible contamination through overtime decay mechanism on the input billing codes and noise injection into the recurrent hidden states, respectively. By doing this, billing codes are reformulated into its temporal patterns with decay rates on each medical variable, and the hidden states of RNNs are regularised by random noises which serve as dropout to improved RNNs robustness towards data variability in terms of missing values and multiple errors. The proposed method is extensively evaluated on real health care data to demonstrate its effectiveness in suggesting medication orders from contaminated values.

cs.LG↗

Few-Shot Deep Adversarial Learning for Video-based Person Re-identification

Video-based person re-identification (re-ID) refers to matching people across camera views from arbitrary unaligned video footages. Existing methods rely on supervision signals to optimise a projected space under which the distances between inter/intra-videos are maximised/minimised. However, this demands exhaustively labelling people across camera views, rendering them unable to be scaled in large networked cameras. Also, it is noticed that learning effective video representations with view invariance is not explicitly addressed for which features exhibit different distributions otherwise. Thus, matching videos for person re-ID demands flexible models to capture the dynamics in time-series observations and learn view-invariant representations with access to limited labeled training samples. In this paper, we propose a novel few-shot deep learning approach to video-based person re-ID, to learn comparable representations that are discriminative and view-invariant. The proposed method is developed on the variational recurrent neural networks (VRNNs) and trained adversarially to produce latent variables with temporal dependencies that are highly discriminative yet view-invariant in matching persons. Through extensive experiments conducted on three benchmark datasets, we empirically show the capability of our method in creating view-invariant temporal features and state-of-the-art performance achieved by our method.

cs.CV↗

Quantum Plasmonic Immunoassay Sensing

Plasmon-polaritons are among the most promising candidates for next generation optical sensors due to their ability to support extremely confined electromagnetic fields and empower strong coupling of light and matter. Here we propose quantum plasmonic immunoassay sensing as an innovative scheme, which embeds immunoassay sensing with recently demonstrated room temperature strong coupling in nanoplasmonic cavities. In our protocol, the antibody-antigen-antibody complex is chemically linked with a quantum emitter label. Placing the quantum-emitter enhanced antibody-antigen-antibody complexes inside or close to a nanoplasmonic (hemisphere dimer) cavity facilitates strong coupling between the plasmon-polaritons and the emitter label resulting in signature Rabi splitting. Through rigorous statistical analysis of multiple analytes randomly distributed on the substrate in extensive realistic computational experiments, we demonstrate a drastic enhancement of the sensitivity up to nearly 1500% compared to conventional shifting-type plasmonic sensors. Most importantly and in stark contrast to classical sensing, we achieve in the strong-coupling (quantum) sensing regime an enhanced sensitivity that is no longer dependent on the concentration of antibody-antigen-antibody complexes -- down to the single-analyte limit. The quantum plasmonic immunoassay scheme thus not only leads to the development of plasmonic bio-sensing for single molecules but also opens up new pathways towards room-temperature quantum sensing enabled by biomolecular inspired protocols linked with quantum nanoplasmonics.

physics.optics↗

Cross-Entropy Adversarial View Adaptation for Person Re-identification

Person re-identification (re-ID) is a task of matching pedestrians under disjoint camera views. To recognise paired snapshots, it has to cope with large cross-view variations caused by the camera view shift. Supervised deep neural networks are effective in producing a set of non-linear projections that can transform cross-view images into a common feature space. However, they typically impose a symmetric architecture, yielding the network ill-conditioned on its optimisation. In this paper, we learn view-invariant subspace for person re-ID, and its corresponding similarity metric using an adversarial view adaptation approach. The main contribution is to learn coupled asymmetric mappings regarding view characteristics which are adversarially trained to address the view discrepancy by optimising the cross-entropy view confusion objective. To determine the similarity value, the network is empowered with a similarity discriminator to promote features that are highly discriminant in distinguishing positive and negative pairs. The other contribution includes an adaptive weighing on the most difficult samples to address the imbalance of within/between-identity pairs. Our approach achieves notable improved performance in comparison to state-of-the-arts on benchmark datasets.

cs.CV↗

Deep Instance-Level Hard Negative Mining Model for Histopathology Images

Histopathology image analysis can be considered as a Multiple instance learning (MIL) problem, where the whole slide histopathology image (WSI) is regarded as a bag of instances (i.e, patches) and the task is to predict a single class label to the WSI. However, in many real-life applications such as computational pathology, discovering the key instances that trigger the bag label is of great interest because it provides reasons for the decision made by the system. In this paper, we propose a deep convolutional neural network (CNN) model that addresses the primary task of a bag classification on a WSI and also learns to identify the response of each instance to provide interpretable results to the final prediction. We incorporate the attention mechanism into the proposed model to operate the transformation of instances and learn attention weights to allow us to find key patches. To perform a balanced training, we introduce adaptive weighing in each training bag to explicitly adjust the weight distribution in order to concentrate more on the contribution of hard samples. Based on the learned attention weights, we further develop a solution to boost the classification performance by generating the bags with hard negative instances. We conduct extensive experiments on colon and breast cancer histopathology data and show that our framework achieves state-of-the-art performance.

cs.CV↗

CORAL8: Concurrent Object Regression for Area Localization in Medical Image Panels

This work tackles the problem of generating a medical report for multi-image panels. We apply our solution to the Renal Direct Immunofluorescence (RDIF) assay which requires a pathologist to generate a report based on observations across the eight different WSI in concert with existing clinical features. To this end, we propose a novel attention-based multi-modal generative recurrent neural network (RNN) architecture capable of dynamically sampling image data concurrently across the RDIF panel. The proposed methodology incorporates text from the clinical notes of the requesting physician to regulate the output of the network to align with the overall clinical context. In addition, we found the importance of regularizing the attention weights for word generation processes. This is because the system can ignore the attention mechanism by assigning equal weights for all members. Thus, we propose two regularizations which force the system to utilize the attention mechanism. Experiments on our novel collection of RDIF WSIs provided by a large clinical laboratory demonstrate that our framework offers significant improvements over existing methods.

cs.CV↗

Optical signatures of Mott-superfluid transition in nitrogen-vacancy centers coupled to photonic crystal cavities

We study the phenomenon of controllable localization-delocalization transition in a quantum many-body system composed of nitrogen-vacancy centers coupled to photonic crystal cavities, through tuning the different detunings and the relative amplitudes of two optical fields that drive two nondegenerate transitions of the $Λ$-type configuration. We not only characterize how dissipation affects the phase boundary using the mean-field quantum master equation, but also provide the possibility of observing this photonic quantum phase transition (QPT) by employing several experimentally observable quantities, such as mean intracavity photon number, density correlation function and emitted spectrum, exhibiting distinct optical signatures in different quantum phases. Such a spin-cavity system opens new perspectives in quantum simulation of condensed-matter and many-body physics in a well-controllable way.

quant-ph↗

An Exciton-Polariton Fano Resonance Driven by Second Harmonic Generation

Angle-resolved second harmonic generation (SHG) spectra of ZnO microwires show characteristic Fano resonances in the spectral vicinity of exciton-polariton modes. The output SHG spectra after SHG interacting with exciton polariton shows a resonant enhancement peak accompanied by a suppression dip originating from the constructive and destructive interference respectively. It is demonstrated that the Fano line shape, and thus the Fano asymmetry parameter q, can be tuned by the phase-shift of the two channels. The phase-dependent q was calculated and the model describes our experimental results well. In particular, the phase-to-q relation unveil the crucial information about the dynamics of the system, e.g., defining the line shape of output SHG spectra in a superposition of quantum states.

physics.optics↗

3D PersonVLAD: Learning Deep Global Representations for Video-based Person Re-identification

In this paper, we introduce a global video representation to video-based person re-identification (re-ID) that aggregates local 3D features across the entire video extent. Most of the existing methods rely on 2D convolutional networks (ConvNets) to extract frame-wise deep features which are pooled temporally to generate the video-level representations. However, 2D ConvNets lose temporal input information immediately after the convolution, and a separate temporal pooling is limited in capturing human motion in shorter sequences. To this end, we present a \textit{global} video representation (3D PersonVLAD), complementary to 3D ConvNets as a novel layer to capture the appearance and motion dynamics in full-length videos. However, encoding each video frame in its entirety and computing an aggregate global representation across all frames is tremendously challenging due to occlusions and misalignments. To resolve this, our proposed network is further augmented with 3D part alignment module to learn local features through soft-attention module. These attended features are statistically aggregated to yield identity-discriminative representations. Our global 3D features are demonstrated to achieve state-of-the-art results on three benchmark datasets: MARS \cite{MARS}, iLIDS-VID \cite{VideoRanking}, and PRID 2011

cs.CV↗

Surface exciton polaritons: a promising mechanism for sensing applications

The possibility of constructing a surface exciton polariton (SEP) based sensor at room temperature is explored. The proposed SEP sensor is based on the Kretschmann-Raether configuration of conventional surface plasmon resonance (SPR) sensor, where the metal thin film was replaced by the J-aggregate cyanine dye film. The excitation of SEP results in a strong electric field at the interface of TDBC and analyte, and exponentially decaying into the analyte, which is sensitive to the refractive index variations of analyte. The sensitivity of 118.1818 $^\circ/\text{RIU}$ (140.4286 $^\circ/\text{RIU}$) was achieved for the proposed SEP sensor within the refractive index range 1.0-1.001 (1.33-1.36) of gaseous analyte (aqueous solutions), which is about 2 (3.5) times higher than that of conventional gold-based SPR sensor. The significant superiority of the SEP sensor in sensitivity revealing SEP as a new promising mechanism for sensing applications.

cond-mat.mes-hall↗

Cycle-Consistent Deep Generative Hashing for Cross-Modal Retrieval

In this paper, we propose a novel deep generative approach to cross-modal retrieval to learn hash functions in the absence of paired training samples through the cycle consistency loss. Our proposed approach employs adversarial training scheme to lean a couple of hash functions enabling translation between modalities while assuming the underlying semantic relationship. To induce the hash codes with semantics to the input-output pair, cycle consistency loss is further proposed upon the adversarial training to strengthen the correlations between inputs and corresponding outputs. Our approach is generative to learn hash functions such that the learned hash codes can maximally correlate each input-output correspondence, meanwhile can also regenerate the inputs so as to minimize the information loss. The learning to hash embedding is thus performed to jointly optimize the parameters of the hash functions across modalities as well as the associated generative models. Extensive experiments on a variety of large-scale cross-modal data sets demonstrate that our proposed method achieves better retrieval results than the state-of-the-arts.

cs.CV↗

Where-and-When to Look: Deep Siamese Attention Networks for Video-based Person Re-identification

Video-based person re-identification (re-id) is a central application in surveillance systems with significant concern in security. Matching persons across disjoint camera views in their video fragments is inherently challenging due to the large visual variations and uncontrolled frame rates. There are two steps crucial to person re-id, namely discriminative feature learning and metric learning. However, existing approaches consider the two steps independently, and they do not make full use of the temporal and spatial information in videos. In this paper, we propose a Siamese attention architecture that jointly learns spatiotemporal video representations and their similarity metrics. The network extracts local convolutional features from regions of each frame, and enhance their discriminative capability by focusing on distinct regions when measuring the similarity with another pedestrian video. The attention mechanism is embedded into spatial gated recurrent units to selectively propagate relevant features and memorize their spatial dependencies through the network. The model essentially learns which parts (\emph{where}) from which frames (\emph{when}) are relevant and distinctive for matching persons and attaches higher importance therein. The proposed Siamese model is end-to-end trainable to jointly learn comparable hidden representations for paired pedestrian videos and their similarity value. Extensive experiments on three benchmark datasets show the effectiveness of each component of the proposed deep network while outperforming state-of-the-art methods.

cs.CV↗

Deep Co-attention based Comparators For Relative Representation Learning in Person Re-identification

Person re-identification (re-ID) requires rapid, flexible yet discriminant representations to quickly generalize to unseen observations on-the-fly and recognize the same identity across disjoint camera views. Recent effective methods are developed in a pair-wise similarity learning system to detect a fixed set of features from distinct regions which are mapped to their vector embeddings for the distance measuring. However, the most relevant and crucial parts of each image are detected independently without referring to the dependency conditioned on one and another. Also, these region based methods rely on spatial manipulation to position the local features in comparable similarity measuring. To combat these limitations, in this paper we introduce the Deep Co-attention based Comparators (DCCs) that fuse the co-dependent representations of the paired images so as to focus on the relevant parts of both images and produce their \textit{relative representations}. Given a pair of pedestrian images to be compared, the proposed model mimics the foveation of human eyes to detect distinct regions concurrent on both images, namely co-dependent features, and alternatively attend to relevant regions to fuse them into the similarity learning. Our comparator is capable of producing dynamic representations relative to a particular sample every time, and thus well-suited to the case of re-identifying pedestrians on-the-fly. We perform extensive experiments to provide the insights and demonstrate the effectiveness of the proposed DCCs in person re-ID. Moreover, our approach has achieved the state-of-the-art performance on three benchmark data sets: DukeMTMC-reID \cite{DukeMTMC}, CUHK03 \cite{FPNN}, and Market-1501 \cite{Market1501}.

cs.CV↗

Beyond Low-Rank Representations: Orthogonal Clustering Basis Reconstruction with Optimized Graph Structure for Multi-view Spectral Clustering

Low-Rank Representation (LRR) is arguably one of the most powerful paradigms for Multi-view spectral clustering, which elegantly encodes the multi-view local graph/manifold structures into an intrinsic low-rank self-expressive data similarity embedded in high-dimensional space, to yield a better graph partition than their single-view counterparts. In this paper we revisit it with a fundamentally different perspective by discovering LRR as essentially a latent clustered orthogonal projection based representation winged with an optimized local graph structure for spectral clustering; each column of the representation is fundamentally a cluster basis orthogonal to others to indicate its members, which intuitively projects the view-specific feature representation to be the one spanned by all orthogonal basis to characterize the cluster structures. Upon this finding, we propose our technique with the followings: (1) We decompose LRR into latent clustered orthogonal representation via low-rank matrix factorization, to encode the more flexible cluster structures than LRR over primal data objects; (2) We convert the problem of LRR into that of simultaneously learning orthogonal clustered representation and optimized local graph structure for each view; (3) The learned orthogonal clustered representations and local graph structures enjoy the same magnitude for multi-view, so that the ideal multi-view consensus can be readily achieved. The experiments over multi-view datasets validate its superiority.

cs.CV↗

Crossing Generative Adversarial Networks for Cross-View Person Re-identification

Person re-identification (\textit{re-id}) refers to matching pedestrians across disjoint yet non-overlapping camera views. The most effective way to match these pedestrians undertaking significant visual variations is to seek reliably invariant features that can describe the person of interest faithfully. Most of existing methods are presented in a supervised manner to produce discriminative features by relying on labeled paired images in correspondence. However, annotating pair-wise images is prohibitively expensive in labors, and thus not practical in large-scale networked cameras. Moreover, seeking comparable representations across camera views demands a flexible model to address the complex distributions of images. In this work, we study the co-occurrence statistic patterns between pairs of images, and propose to crossing Generative Adversarial Network (Cross-GAN) for learning a joint distribution for cross-image representations in a unsupervised manner. Given a pair of person images, the proposed model consists of the variational auto-encoder to encode the pair into respective latent variables, a proposed cross-view alignment to reduce the view disparity, and an adversarial layer to seek the joint distribution of latent representations. The learned latent representations are well-aligned to reflect the co-occurrence patterns of paired images. We empirically evaluate the proposed model against challenging datasets, and our results show the importance of joint invariant features in improving matching rates of person re-id with comparison to semi/unsupervised state-of-the-arts.

cs.CV↗

Multi-View Spectral Clustering via Structured Low-Rank Matrix Factorization

Multi-view data clustering attracts more attention than their single view counterparts due to the fact that leveraging multiple independent and complementary information from multi-view feature spaces outperforms the single one. Multi-view Spectral Clustering aims at yielding the data partition agreement over their local manifold structures by seeking eigenvalue-eigenvector decompositions. However, as we observed, such classical paradigm still suffers from (1) overlooking the flexible local manifold structure, caused by (2) enforcing the low-rank data correlation agreement among all views; worse still, (3) LRR is not intuitively flexible to capture the latent data clustering structures. In this paper, we present the structured LRR by factorizing into the latent low-dimensional data-cluster representations, which characterize the data clustering structure for each view. Upon such representation, (b) the laplacian regularizer is imposed to be capable of preserving the flexible local manifold structure for each view. (c) We present an iterative multi-view agreement strategy by minimizing the divergence objective among all factorized latent data-cluster representations during each iteration of optimization process, where such latent representation from each view serves to regulate those from other views, such intuitive process iteratively coordinates all views to be agreeable. (d) We remark that such data-cluster representation can flexibly encode the data clustering structure from any view with adaptive input cluster number. To this end, (e) a novel non-convex objective function is proposed via the efficient alternating minimization strategy. The complexity analysis are also presented. The extensive experiments conducted against the real-world multi-view datasets demonstrate the superiority over state-of-the-arts.

cs.CV↗

Structured Deep Hashing with Convolutional Neural Networks for Fast Person Re-identification

Given a pedestrian image as a query, the purpose of person re-identification is to identify the correct match from a large collection of gallery images depicting the same person captured by disjoint camera views. The critical challenge is how to construct a robust yet discriminative feature representation to capture the compounded variations in pedestrian appearance. To this end, deep learning methods have been proposed to extract hierarchical features against extreme variability of appearance. However, existing methods in this category generally neglect the efficiency in the matching stage whereas the searching speed of a re-identification system is crucial in real-world applications. In this paper, we present a novel deep hashing framework with Convolutional Neural Networks (CNNs) for fast person re-identification. Technically, we simultaneously learn both CNN features and hash functions/codes to get robust yet discriminative features and similarity-preserving hash codes. Thereby, person re-identification can be resolved by efficiently computing and ranking the Hamming distances between images. A structured loss function defined over positive pairs and hard negatives is proposed to formulate a novel optimization problem so that fast convergence and more stable optimized solution can be obtained. Extensive experiments on two benchmarks CUHK03 \cite{FPNN} and Market-1501 \cite{Market1501} show that the proposed deep architecture is efficacy over state-of-the-arts.

cs.CV↗

Design of an optimized $\text{MoS}_2$-based highly sensitive near-infrared surface plasmon resonance imaging biosensor

A surface plasmon resonance imaging biosensor based on $\text{MoS}_2$ deposited on Aluminium substrate is designed for high imaging sensitivity and detection accuracy. The proposed biosensor exhibits better performance than graphene-based biosensor in the near-infrared regime. A high imaging sensitivity of more than 970 $\text{RIU}^{-1}$ is obtained at the wavelength of 1540 nm. The effect of aluminium thickness, number of $\text{MoS}_2$ layers and the refractive index of sensing layer are investigated to obtain an optimized design for high sensor performance. In addition, the sensor performance comparison of $\text{MoS}_2$ and other two-dimensional transition metal dichalcogenide materials based biosensor in the near-infrared regime are also presented. The designed $\text{MoS}_2$ mediated surface plasmon resonance imaging biosensor could provide potential applications in surface plasmon resonance imaging detection of multiple biomolecular interactions simultaneously.

cond-mat.mes-hall↗