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Lingyu Chen

Publications and source records attributed to Lingyu Chen.

6 recordsLinked to original sources

Learning to Beat: Phenotype-Guided Latent Flow with Regional Motion Priors for Biventricular Motion Synthesis

Full-cycle biventricular geometry is essential for characterizing cardiac function. However, dense and temporally consistent 3D+t biventricular meshes are not routinely available, whereas end-diastolic (ED) anatomy can often be obtained reliably. We therefore investigate full-cycle biventricular motion synthesis from a single ED mesh. This task is challenging because cardiac deformation is spatially heterogeneous and phenotype dependent, while conventional global generative models often obscure localized motion patterns. In this study, we propose a region-specific and phenotype-adaptive framework that integrates motion-informed functional parcellation with conditional latent flow. A functional partition learned from reconstructed motion organizes the ventricular surface into regions with coherent dynamics and enables topology-aware regional feature exchange. A phenotype-conditioned rectified-flow model subsequently maps the ED anatomy to full-cycle motion latents through fine-grained conditioning and prototype-routed motion adapters. An optional control branch further incorporates available motion descriptors for controllable synthesis. Experiments on ACDC, M\&Ms, and M\&Ms-2 demonstrate consistent improvements in geometric accuracy and functional fidelity. Under ED-only synthesis, our method achieves biventricular ASSD, HD95, and vRMSE of \(1.49\pm0.34\)~mm, \(3.77\pm1.06\)~mm, and \(3.31\pm1.03\)~mm, respectively, outperforming all competing methods. Complementary functional and robustness evaluations further demonstrate that the synthesized sequences preserve physiologically plausible ventricular dynamics and generalize across cohorts and disease phenotypes. The code will be released publicly upon acceptance of the manuscript for publication.

cs.CV

RePCM: Region-Specific and Phenotype-Adaptive Bi-Ventricular Cardiac Motion Synthesis

Cardiac motion over a cardiac cycle is crucial for quantifying regional function and is strongly affected by cardiovascular diseases. Since temporally dense mesh sequences are difficult to obtain in practice, we focus on leveraging the more accessible end-diastolic frame to infer a full-cycle sequence. Due to strong regional and disease-specific differences, traditional methods often oversmooth the data by relying on generative models that are optimized for global patterns. To address this problem, we propose Region-Aware and Phenotype-Adaptive Bi-Ventricular Cardiac Motion Synthesis (RePCM) for single frame Bi-ventricular mesh motion completion. In Stage I, a reconstruction network learns vertex wise motion descriptors and clustering yields a data driven functional partition, providing an explicit motion derived region structure. In Stage II, a Region-Specific Injection Module enforces masked, synchronized region exchange within a conditional VAE, preserving localized specific dynamics and restricting cross-region mixing. A Phenotype-Adaptive Mixture-of-Experts prior conditioned on ED shape uses anatomy-guided cues to model latent motion trends and capture inter-disease variability. Experiments on three datasets covering different cardiovascular diseases show consistent gains in geometric and functional metrics and improved preservation of region specific dynamics.

cs.CV

COME: Dual Structure-Semantic Learning with Collaborative MoE for Universal Lesion Detection Across Heterogeneous Ultrasound Datasets

Conventional single-dataset training often fails with new data distributions, especially in ultrasound (US) image analysis due to limited data, acoustic shadows, and speckle noise. Therefore, constructing a universal framework for multi-heterogeneous US datasets is imperative. However, a key challenge arises: how to effectively mitigate inter-dataset interference while preserving dataset-specific discriminative features for robust downstream task? Previous approaches utilize either a single source-specific decoder or a domain adaptation strategy, but these methods experienced a decline in performance when applied to other domains. Considering this, we propose a Universal Collaborative Mixture of Heterogeneous Source-Specific Experts (COME). Specifically, COME establishes dual structure-semantic shared experts that create a universal representation space and then collaborate with source-specific experts to extract discriminative features through providing complementary features. This design enables robust generalization by leveraging cross-datasets experience distributions and providing universal US priors for small-batch or unseen data scenarios. Extensive experiments under three evaluation modes (single-dataset, intra-organ, and inter-organ integration datasets) demonstrate COME's superiority, achieving significant mean AP improvements over state-of-the-art methods. Our project is available at: https://universalcome.github.io/UniversalCOME/.

cs.CV

SelfMedHPM: Self Pre-training With Hard Patches Mining Masked Autoencoders For Medical Image Segmentation

In recent years, deep learning methods such as convolutional neural network (CNN) and transformers have made significant progress in CT multi-organ segmentation. However, CT multi-organ segmentation methods based on masked image modeling (MIM) are very limited. There are already methods using MAE for CT multi-organ segmentation task, we believe that the existing methods do not identify the most difficult areas to reconstruct. To this end, we propose a MIM self-training framework with hard patches mining masked autoencoders for CT multi-organ segmentation tasks (selfMedHPM). The method performs ViT self-pretraining on the training set of the target data and introduces an auxiliary loss predictor, which first predicts the patch loss and determines the location of the next mask. SelfMedHPM implementation is better than various competitive methods in abdominal CT multi-organ segmentation and body CT multi-organ segmentation. We have validated the performance of our method on the Multi Atlas Labeling Beyond The Cranial Vault (BTCV) dataset for abdomen mult-organ segmentation and the SinoMed Whole Body (SMWB) dataset for body multi-organ segmentation tasks.

cs.CV

Research on a New Convolutional Neural Network Model Combined with Random Edges Adding

It is always a hot and difficult point to improve the accuracy of convolutional neural network model and speed up its convergence. Based on the idea of small world network, a random edge adding algorithm is proposed to improve the performance of convolutional neural network model. This algorithm takes the convolutional neural network model as a benchmark, and randomizes backwards and cross-layer connections with probability p to form a new convolutional neural network model. The proposed idea can optimize the cross layer connectivity by changing the topological structure of convolutional neural network, and provide a new idea for the improvement of the model. The simulation results based on Fashion-MINST and cifar10 data set show that the model recognition accuracy and training convergence speed are greatly improved by random edge adding reconstructed models with aprobability p = 0.1.

cs.NE

Capacity and Delay Tradeoff of Secondary Cellular Networks with Spectrum Aggregation

Cellular communication networks are plagued with redundant capacity, which results in low utilization and cost-effectiveness of network capital investments. The redundant capacity can be exploited to deliver secondary traffic that is ultra-elastic and delay-tolerant. In this paper, we propose an analytical framework to study the capacity-delay tradeoff of elastic/secondary traffic in large scale cellular networks with spectrum aggregation. Our framework integrates stochastic geometry and queueing theory models and gives analytical insights into the capacity-delay performance in the interference limited regime. Closed-form results are obtained to characterize the mean delay and delay distribution as functions of per user throughput capacity. The impacts of spectrum aggregation, user and base station (BS) densities, traffic session payload, and primary traffic dynamics on the capacity-delay tradeoff relationship are investigated. The fundamental capacity limit is derived and its scaling behavior is revealed. Our analysis shows the feasibility of providing secondary communication services over cellular networks and highlights some critical design issues.

cs.NI