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Linlin Shen

Publications and source records attributed to Linlin Shen.

At least 55 records · Page 3Linked to original sources

MMedExpert-R1: Strengthening Multimodal Medical Reasoning via Domain-Specific Adaptation and Clinical Guideline Reinforcement

Medical Vision-Language Models (MedVLMs) excel at perception tasks but struggle with complex clinical reasoning required in real-world scenarios. While reinforcement learning (RL) has been explored to enhance reasoning capabilities, existing approaches face critical mismatches: the scarcity of deep reasoning data, cold-start limits multi-specialty alignment, and standard RL algorithms fail to model clinical reasoning diversity. We propose MMedExpert-R1, a novel reasoning MedVLM that addresses these challenges through domain-specific adaptation and clinical guideline reinforcement. We construct MMedExpert, a high-quality dataset of 10K samples across four specialties with step-by-step reasoning traces. Our Domain-Specific Adaptation (DSA) creates specialty-specific LoRA modules to provide diverse initialization, while Guideline-Based Advantages (GBA) explicitly models different clinical reasoning perspectives to align with real-world diagnostic strategies. Conflict-Aware Capability Integration then merges these specialized experts into a unified agent, ensuring robust multi-specialty alignment. Comprehensive experiments demonstrate state-of-the-art performance, with our 7B model achieving 27.50 on MedXpert-MM and 83.03 on OmniMedVQA, establishing a robust foundation for reliable multimodal medical reasoning systems.

cs.CV↗

Benchmarking Egocentric Clinical Intent Understanding Capability for Medical Multimodal Large Language Models

Medical Multimodal Large Language Models (Med-MLLMs) require egocentric clinical intent understanding for real-world deployment, yet existing benchmarks fail to evaluate this critical capability. To address these challenges, we introduce MedGaze-Bench, the first benchmark leveraging clinician gaze as a Cognitive Cursor to assess intent understanding across surgery, emergency simulation, and diagnostic interpretation. Our benchmark addresses three fundamental challenges: visual homogeneity of anatomical structures, strict temporal-causal dependencies in clinical workflows, and implicit adherence to safety protocols. We propose a Three-Dimensional Clinical Intent Framework evaluating: (1) Spatial Intent: discriminating precise targets amid visual noise, (2) Temporal Intent: inferring causal rationale through retrospective and prospective reasoning, and (3) Standard Intent: verifying protocol compliance through safety checks. Beyond accuracy metrics, we introduce Trap QA mechanisms to stress-test clinical reliability by penalizing hallucinations and cognitive sycophancy. Experiments reveal current MLLMs struggle with egocentric intent due to over-reliance on global features, leading to fabricated observations and uncritical acceptance of invalid instructions.

cs.CV↗

A Lightweight 3D Anomaly Detection Method with Rotationally Invariant Features

3D anomaly detection (AD) is a crucial task in computer vision, aiming to identify anomalous points or regions from point cloud data. However, existing methods may encounter challenges when handling point clouds with changes in orientation and position because the resulting features may vary significantly. To address this problem, we propose a novel Rotationally Invariant Features (RIF) framework for 3D AD. Firstly, to remove the adverse effect of variations on point cloud data, we develop a Point Coordinate Mapping (PCM) technique, which maps each point into a rotationally invariant space to maintain consistency of representation. Then, to learn robust and discriminative features, we design a lightweight Convolutional Transform Feature Network (CTF-Net) to extract rotationally invariant features for the memory bank. To improve the ability of the feature extractor, we introduce the idea of transfer learning to pre-train the feature extractor with 3D data augmentation. Experimental results show that the proposed method achieves the advanced performance on the Anomaly-ShapeNet dataset, with an average P-AUROC improvement of 17.7\%, and also gains the best performance on the Real3D-AD dataset, with an average P-AUROC improvement of 1.6\%. The strong generalization ability of RIF has been verified by combining it with traditional feature extraction methods on anomaly detection tasks, demonstrating great potential for industrial applications.

cs.CV↗

SSA3D: Text-Conditioned Assisted Self-Supervised Framework for Automatic Dental Abutment Design

Abutment design is a critical step in dental implant restoration. However, manual design involves tedious measurement and fitting, and research on automating this process with AI is limited, due to the unavailability of large annotated datasets. Although self-supervised learning (SSL) can alleviate data scarcity, its need for pre-training and fine-tuning results in high computational costs and long training times. In this paper, we propose a Self-supervised assisted automatic abutment design framework (SS$A^3$D), which employs a dual-branch architecture with a reconstruction branch and a regression branch. The reconstruction branch learns to restore masked intraoral scan data and transfers the learned structural information to the regression branch. The regression branch then predicts the abutment parameters under supervised learning, which eliminates the separate pre-training and fine-tuning process. We also design a Text-Conditioned Prompt (TCP) module to incorporate clinical information (such as implant location, system, and series) into SS$A^3$D. This guides the network to focus on relevant regions and constrains the parameter predictions. Extensive experiments on a collected dataset show that SS$A^3$D saves half of the training time and achieves higher accuracy than traditional SSL methods. It also achieves state-of-the-art performance compared to other methods, significantly improving the accuracy and efficiency of automated abutment design.

cs.CV↗

OralGPT-Omni: A Versatile Dental Multimodal Large Language Model

Multimodal Large Language Models (MLLMs) have exhibited immense potential across numerous medical specialties; yet, dentistry remains underexplored, in part due to limited domain-specific data, scarce dental expert annotations, insufficient modality-specific modeling, and challenges in reliability. In this paper, we present OralGPT-Omni, the first dental-specialized MLLM designed for comprehensive and trustworthy analysis across diverse dental imaging modalities and clinical tasks. To explicitly capture dentists' diagnostic reasoning, we construct TRACE-CoT, a clinically grounded chain-of-thought dataset that mirrors dental radiologists' decision-making processes. This reasoning supervision, combined with our proposed four-stage training paradigm, substantially strengthens the model's capacity for dental image understanding and analysis. In parallel, we introduce MMOral-Uni, the first unified multimodal benchmark for dental image analysis. It comprises 2,809 open-ended question-answer pairs spanning five modalities and five tasks, offering a comprehensive evaluation suite to date for MLLMs in digital dentistry. OralGPT-Omni achieves an overall score of 51.84 on the MMOral-Uni benchmark and 45.31 on the MMOral-OPG benchmark, dramatically outperforming the scores of GPT-5. Our work promotes intelligent dentistry and paves the way for future advances in dental image analysis. All code, benchmark, and models will be made publicly available.

cs.CV↗

Text Condition Embedded Regression Network for Automated Dental Abutment Design

The abutment is an important part of artificial dental implants, whose design process is time-consuming and labor-intensive. Long-term use of inappropriate dental implant abutments may result in implant complications, including peri-implantitis. Using artificial intelligence to assist dental implant abutment design can quickly improve the efficiency of abutment design and enhance abutment adaptability. In this paper, we propose a text condition embedded abutment design framework (TCEAD), the novel automated abutment design solution available in literature. The proposed study extends the self-supervised learning framework of the mesh mask autoencoder (MeshMAE) by introducing a text-guided localization (TGL) module to facilitate abutment area localization. As the parameter determination of the abutment is heavily dependent on local fine-grained features (the width and height of the implant and the distance to the opposing tooth), we pre-train the encoder using oral scan data to improve the model's feature extraction ability. Moreover, considering that the abutment area is only a small part of the oral scan data, we designed a TGL module, which introduces the description of the abutment area through the text encoder of Contrastive Language-Image Pre-training (CLIP), enabling the network to quickly locate the abutment area. We validated the performance of TCEAD on a large abutment design dataset. Extensive experiments demonstrate that TCEAD achieves an Intersection over Union (IoU) improvement of 0.8%-12.85% over other mainstream methods, underscoring its potential in automated dental abutment design.

cs.CV↗

FineXtrol: Controllable Motion Generation via Fine-Grained Text

Recent works have sought to enhance the controllability and precision of text-driven motion generation. Some approaches leverage large language models (LLMs) to produce more detailed texts, while others incorporate global 3D coordinate sequences as additional control signals. However, the former often introduces misaligned details and lacks explicit temporal cues, and the latter incurs significant computational cost when converting coordinates to standard motion representations. To address these issues, we propose FineXtrol, a novel control framework for efficient motion generation guided by temporally-aware, precise, user-friendly, and fine-grained textual control signals that describe specific body part movements over time. In support of this framework, we design a hierarchical contrastive learning module that encourages the text encoder to produce more discriminative embeddings for our novel control signals, thereby improving motion controllability. Quantitative results show that FineXtrol achieves strong performance in controllable motion generation, while qualitative analysis demonstrates its flexibility in directing specific body part movements.

cs.CV↗

UINO-FSS: Unifying Representation Learning and Few-shot Segmentation via Hierarchical Distillation and Mamba-HyperCorrelation

Few-shot semantic segmentation has attracted growing interest for its ability to generalize to novel object categories using only a few annotated samples. To address data scarcity, recent methods incorporate multiple foundation models to improve feature transferability and segmentation performance. However, they often rely on dual-branch architectures that combine pre-trained encoders to leverage complementary strengths, a design that limits flexibility and efficiency. This raises a fundamental question: can we build a unified model that integrates knowledge from different foundation architectures? Achieving this is, however, challenging due to the misalignment between class-agnostic segmentation capabilities and fine-grained discriminative representations. To this end, we present UINO-FSS, a novel framework built on the key observation that early-stage DINOv2 features exhibit distribution consistency with SAM's output embeddings. This consistency enables the integration of both models' knowledge into a single-encoder architecture via coarse-to-fine multimodal distillation. In particular, our segmenter consists of three core components: a bottleneck adapter for embedding alignment, a meta-visual prompt generator that leverages dense similarity volumes and semantic embeddings, and a mask decoder. Using hierarchical cross-model distillation, we effectively transfer SAM's knowledge into the segmenter, further enhanced by Mamba-based 4D correlation mining on support-query pairs. Extensive experiments on PASCAL-5$^i$ and COCO-20$^i$ show that UINO-FSS achieves new state-of-the-art results under the 1-shot setting, with mIoU of 80.6 (+3.8%) on PASCAL-5$^i$ and 64.5 (+4.1%) on COCO-20$^i$, demonstrating the effectiveness of our unified approach.

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SurvAgent: Hierarchical CoT-Enhanced Case Banking and Dichotomy-Based Multi-Agent System for Multimodal Survival Prediction

Survival analysis is critical for cancer prognosis and treatment planning, yet existing methods lack the transparency essential for clinical adoption. While recent pathology agents have demonstrated explainability in diagnostic tasks, they face three limitations for survival prediction: inability to integrate multimodal data, ineffective region-of-interest exploration, and failure to leverage experiential learning from historical cases. We introduce SurvAgent, the first hierarchical chain-of-thought (CoT)-enhanced multi-agent system for multimodal survival prediction. SurvAgent consists of two stages: (1) WSI-Gene CoT-Enhanced Case Bank Construction employs hierarchical analysis through Low-Magnification Screening, Cross-Modal Similarity-Aware Patch Mining, and Confidence-Aware Patch Mining for pathology images, while Gene-Stratified analysis processes six functional gene categories. Both generate structured reports with CoT reasoning, storing complete analytical processes for experiential learning. (2) Dichotomy-Based Multi-Expert Agent Inference retrieves similar cases via RAG and integrates multimodal reports with expert predictions through progressive interval refinement. Extensive experiments on five TCGA cohorts demonstrate SurvAgent's superority over conventional methods, proprietary MLLMs, and medical agents, establishing a new paradigm for explainable AI-driven survival prediction in precision oncology.

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Benchmarking Foundation Models and Parameter-Efficient Fine-Tuning for Prognosis Prediction in Medical Imaging

Despite the significant potential of Foundation Models (FMs) in medical imaging, their application to prognosis prediction remains challenging due to data scarcity, class imbalance, and task complexity, which limit their clinical adoption. This study introduces the first structured benchmark to assess the robustness and efficiency of transfer learning strategies for FMs compared with convolutional neural networks (CNNs) in predicting COVID-19 patient outcomes from chest X-rays. The goal is to systematically compare finetuning strategies, both classical and parameter efficient, under realistic clinical constraints related to data scarcity and class imbalance, offering empirical guidance for AI deployment in clinical workflows. Four publicly available COVID-19 chest X-ray datasets were used, covering mortality, severity, and ICU admission, with varying sample sizes and class imbalances. CNNs pretrained on ImageNet and FMs pretrained on general or biomedical datasets were adapted using full finetuning, linear probing, and parameter-efficient methods. Models were evaluated under full data and few shot regimes using the Matthews Correlation Coefficient (MCC) and Precision Recall AUC (PR-AUC), with cross validation and class weighted losses. CNNs with full fine-tuning performed robustly on small, imbalanced datasets, while FMs with Parameter-Efficient Fine-Tuning (PEFT), particularly LoRA and BitFit, achieved competitive results on larger datasets. Severe class imbalance degraded PEFT performance, whereas balanced data mitigated this effect. In few-shot settings, FMs showed limited generalization, with linear probing yielding the most stable results. No single fine-tuning strategy proved universally optimal: CNNs remain dependable for low-resource scenarios, whereas FMs benefit from parameter-efficient methods when data are sufficient.

cs.CV↗

Enhancing Adversarial Transferability by Balancing Exploration and Exploitation with Gradient-Guided Sampling

Adversarial attacks present a critical challenge to deep neural networks' robustness, particularly in transfer scenarios across different model architectures. However, the transferability of adversarial attacks faces a fundamental dilemma between Exploitation (maximizing attack potency) and Exploration (enhancing cross-model generalization). Traditional momentum-based methods over-prioritize Exploitation, i.e., higher loss maxima for attack potency but weakened generalization (narrow loss surface). Conversely, recent methods with inner-iteration sampling over-prioritize Exploration, i.e., flatter loss surfaces for cross-model generalization but weakened attack potency (suboptimal local maxima). To resolve this dilemma, we propose a simple yet effective Gradient-Guided Sampling (GGS), which harmonizes both objectives through guiding sampling along the gradient ascent direction to improve both sampling efficiency and stability. Specifically, based on MI-FGSM, GGS introduces inner-iteration random sampling and guides the sampling direction using the gradient from the previous inner-iteration (the sampling's magnitude is determined by a random distribution). This mechanism encourages adversarial examples to reside in balanced regions with both flatness for cross-model generalization and higher local maxima for strong attack potency. Comprehensive experiments across multiple DNN architectures and multimodal large language models (MLLMs) demonstrate the superiority of our method over state-of-the-art transfer attacks. Code is made available at https://github.com/anuin-cat/GGS.

cs.LG↗

Context-Gated Cross-Modal Perception with Visual Mamba for PET-CT Lung Tumor Segmentation

Accurate lung tumor segmentation is vital for improving diagnosis and treatment planning, and effectively combining anatomical and functional information from PET and CT remains a major challenge. In this study, we propose vMambaX, a lightweight multimodal framework integrating PET and CT scan images through a Context-Gated Cross-Modal Perception Module (CGM). Built on the Visual Mamba architecture, vMambaX adaptively enhances inter-modality feature interaction, emphasizing informative regions while suppressing noise. Evaluated on the PCLT20K dataset, the model outperforms baseline models while maintaining lower computational complexity. These results highlight the effectiveness of adaptive cross-modal gating for multimodal tumor segmentation and demonstrate the potential of vMambaX as an efficient and scalable framework for advanced lung cancer analysis. The code is available at https://github.com/arco-group/vMambaX.

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DAP-MAE: Domain-Adaptive Point Cloud Masked Autoencoder for Effective Cross-Domain Learning

Compared to 2D data, the scale of point cloud data in different domains available for training, is quite limited. Researchers have been trying to combine these data of different domains for masked autoencoder (MAE) pre-training to leverage such a data scarcity issue. However, the prior knowledge learned from mixed domains may not align well with the downstream 3D point cloud analysis tasks, leading to degraded performance. To address such an issue, we propose the Domain-Adaptive Point Cloud Masked Autoencoder (DAP-MAE), an MAE pre-training method, to adaptively integrate the knowledge of cross-domain datasets for general point cloud analysis. In DAP-MAE, we design a heterogeneous domain adapter that utilizes an adaptation mode during pre-training, enabling the model to comprehensively learn information from point clouds across different domains, while employing a fusion mode in the fine-tuning to enhance point cloud features. Meanwhile, DAP-MAE incorporates a domain feature generator to guide the adaptation of point cloud features to various downstream tasks. With only one pre-training, DAP-MAE achieves excellent performance across four different point cloud analysis tasks, reaching 95.18% in object classification on ScanObjectNN and 88.45% in facial expression recognition on Bosphorus.

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GPTFace: Generative Pre-training of Facial-Linguistic Transformer by Span Masking and Weakly Correlated Text-image Data

Compared to the prosperity of pre-training models in natural image understanding, the research on large-scale pre-training models for facial knowledge learning is still limited. Current approaches mainly rely on manually assembled and annotated face datasets for training, but labeling such datasets is labor-intensive and the trained models have limited scalability beyond the training data. To address these limitations, we present a generative pre-training model for facial knowledge learning that leverages large-scale web-built data for training. We use texts and images containing human faces crawled from the internet and conduct pre-training on self-supervised tasks, including masked image/language modeling (MILM) and image-text matching (ITM). During the generation stage, we further utilize the image-text matching loss to pull the generation distribution towards the control signal for controllable image/text generation. Experimental results demonstrate that our model achieves comparable performance to state-of-the-art pre-training models for various facial downstream tasks, such as attribution classification and expression recognition. Furthermore, our approach is also applicable to a wide range of face editing tasks, including face attribute editing, expression manipulation, mask removal, and photo inpainting.

cs.CV↗

LightQANet: Quantized and Adaptive Feature Learning for Low-Light Image Enhancement

Low-light image enhancement (LLIE) aims to improve illumination while preserving high-quality color and texture. However, existing methods often fail to extract reliable feature representations due to severely degraded pixel-level information under low-light conditions, resulting in poor texture restoration, color inconsistency, and artifact. To address these challenges, we propose LightQANet, a novel framework that introduces quantized and adaptive feature learning for low-light enhancement, aiming to achieve consistent and robust image quality across diverse lighting conditions. From the static modeling perspective, we design a Light Quantization Module (LQM) to explicitly extract and quantify illumination-related factors from image features. By enforcing structured light factor learning, LQM enhances the extraction of light-invariant representations and mitigates feature inconsistency across varying illumination levels. From the dynamic adaptation perspective, we introduce a Light-Aware Prompt Module (LAPM), which encodes illumination priors into learnable prompts to dynamically guide the feature learning process. LAPM enables the model to flexibly adapt to complex and continuously changing lighting conditions, further improving image enhancement. Extensive experiments on multiple low-light datasets demonstrate that our method achieves state-of-the-art performance, delivering superior qualitative and quantitative results across various challenging lighting scenarios.

cs.CV↗

IAD-GPT: Advancing Visual Knowledge in Multimodal Large Language Model for Industrial Anomaly Detection

The robust causal capability of Multimodal Large Language Models (MLLMs) hold the potential of detecting defective objects in Industrial Anomaly Detection (IAD). However, most traditional IAD methods lack the ability to provide multi-turn human-machine dialogues and detailed descriptions, such as the color of objects, the shape of an anomaly, or specific types of anomalies. At the same time, methods based on large pre-trained models have not fully stimulated the ability of large models in anomaly detection tasks. In this paper, we explore the combination of rich text semantics with both image-level and pixel-level information from images and propose IAD-GPT, a novel paradigm based on MLLMs for IAD. We employ Abnormal Prompt Generator (APG) to generate detailed anomaly prompts for specific objects. These specific prompts from the large language model (LLM) are used to activate the detection and segmentation functions of the pre-trained visual-language model (i.e., CLIP). To enhance the visual grounding ability of MLLMs, we propose Text-Guided Enhancer, wherein image features interact with normal and abnormal text prompts to dynamically select enhancement pathways, which enables language models to focus on specific aspects of visual data, enhancing their ability to accurately interpret and respond to anomalies within images. Moreover, we design a Multi-Mask Fusion module to incorporate mask as expert knowledge, which enhances the LLM's perception of pixel-level anomalies. Extensive experiments on MVTec-AD and VisA datasets demonstrate our state-of-the-art performance on self-supervised and few-shot anomaly detection and segmentation tasks, such as MVTec-AD and VisA datasets. The codes are available at \href{https://github.com/LiZeWen1225/IAD-GPT}{https://github.com/LiZeWen1225/IAD-GPT}.

cs.CV↗

Medchain: Bridging the Gap Between LLM Agents and Clinical Practice with Interactive Sequence

Clinical decision making (CDM) is a complex, dynamic process crucial to healthcare delivery, yet it remains a significant challenge for artificial intelligence systems. While Large Language Model (LLM)-based agents have been tested on general medical knowledge using licensing exams and knowledge question-answering tasks, their performance in the CDM in real-world scenarios is limited due to the lack of comprehensive testing datasets that mirror actual medical practice. To address this gap, we present MedChain, a dataset of 12,163 clinical cases that covers five key stages of clinical workflow. MedChain distinguishes itself from existing benchmarks with three key features of real-world clinical practice: personalization, interactivity, and sequentiality. Further, to tackle real-world CDM challenges, we also propose MedChain-Agent, an AI system that integrates a feedback mechanism and a MCase-RAG module to learn from previous cases and adapt its responses. MedChain-Agent demonstrates remarkable adaptability in gathering information dynamically and handling sequential clinical tasks, significantly outperforming existing approaches.

cs.CL↗

EyePCR: A Comprehensive Benchmark for Fine-Grained Perception, Knowledge Comprehension and Clinical Reasoning in Ophthalmic Surgery

MLLMs (Multimodal Large Language Models) have showcased remarkable capabilities, but their performance in high-stakes, domain-specific scenarios like surgical settings, remains largely under-explored. To address this gap, we develop \textbf{EyePCR}, a large-scale benchmark for ophthalmic surgery analysis, grounded in structured clinical knowledge to evaluate cognition across \textit{Perception}, \textit{Comprehension} and \textit{Reasoning}. EyePCR offers a richly annotated corpus with more than 210k VQAs, which cover 1048 fine-grained attributes for multi-view perception, medical knowledge graph of more than 25k triplets for comprehension, and four clinically grounded reasoning tasks. The rich annotations facilitate in-depth cognitive analysis, simulating how surgeons perceive visual cues and combine them with domain knowledge to make decisions, thus greatly improving models' cognitive ability. In particular, \textbf{EyePCR-MLLM}, a domain-adapted variant of Qwen2.5-VL-7B, achieves the highest accuracy on MCQs for \textit{Perception} among compared models and outperforms open-source models in \textit{Comprehension} and \textit{Reasoning}, rivalling commercial models like GPT-4.1. EyePCR reveals the limitations of existing MLLMs in surgical cognition and lays the foundation for benchmarking and enhancing clinical reliability of surgical video understanding models.

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