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Linling Li

Publications and source records attributed to Linling Li.

6 recordsLinked to original sources

NeuroAlign: Hierarchical Multimodal Fusion of Dynamic and Structural Neuroimaging for MCI Analysis

Multimodal neuroimaging fusion of functional MRI (fMRI) and diffusion tensor imaging (DTI) provides complementary information for cognitive impairment analysis, but remains challenged by heterogeneous feature spaces and misaligned representations. We propose \textit{NeuroAlign}, a hierarchical framework for structured multimodal fusion. It introduces (1) \textit{Dual-Modal Hierarchical Alignment} (DMHA), which models multi-scale dynamic connectivity and aligns dynamic-static and functional-structural embeddings; and (2) \textit{Dual-Domain Hierarchical Interaction} (DDHI), which enables fine-grained modulation and global interaction between connectivity- and region-level features. To support feature-level inspection, we design \textit{Synergistic Activation Mapping} (SAM), a gradient-free, marker-oriented attribution method for DFC, SFC, ALFF, and FA. Evaluated on GUTCM, ADNI, and OASIS under five-fold validation, NeuroAlign achieves competitive MCI/SCD detection and preliminary cross-dataset transferability. Attribution analyses reveal modality-specific and partially consistent brain patterns, providing model-derived evidence for multimodal representation analysis.

cs.CV

HA-HI: Synergising fMRI and DTI through Hierarchical Alignments and Hierarchical Interactions for Mild Cognitive Impairment Diagnosis

Early diagnosis of mild cognitive impairment (MCI) and subjective cognitive decline (SCD) utilizing multi-modal magnetic resonance imaging (MRI) is a pivotal area of research. While various regional and connectivity features from functional MRI (fMRI) and diffusion tensor imaging (DTI) have been employed to develop diagnosis models, most studies integrate these features without adequately addressing their alignment and interactions. This limits the potential to fully exploit the synergistic contributions of combined features and modalities. To solve this gap, our study introduces a novel Hierarchical Alignments and Hierarchical Interactions (HA-HI) method for MCI and SCD classification, leveraging the combined strengths of fMRI and DTI. HA-HI efficiently learns significant MCI- or SCD- related regional and connectivity features by aligning various feature types and hierarchically maximizing their interactions. Furthermore, to enhance the interpretability of our approach, we have developed the Synergistic Activation Map (SAM) technique, revealing the critical brain regions and connections that are indicative of MCI/SCD. Comprehensive evaluations on the ADNI dataset and our self-collected data demonstrate that HA-HI outperforms other existing methods in diagnosing MCI and SCD, making it a potentially vital and interpretable tool for early detection. The implementation of this method is publicly accessible at https://github.com/ICI-BCI/Dual-MRI-HA-HI.git.

eess.IV

EEGMatch: Learning with Incomplete Labels for Semi-Supervised EEG-based Cross-Subject Emotion Recognition

Electroencephalography (EEG) is an objective tool for emotion recognition and shows promising performance. However, the label scarcity problem is a main challenge in this field, which limits the wide application of EEG-based emotion recognition. In this paper, we propose a novel semi-supervised learning framework (EEGMatch) to leverage both labeled and unlabeled EEG data. First, an EEG-Mixup based data augmentation method is developed to generate more valid samples for model learning. Second, a semi-supervised two-step pairwise learning method is proposed to bridge prototype-wise and instance-wise pairwise learning, where the prototype-wise pairwise learning measures the global relationship between EEG data and the prototypical representation of each emotion class and the instance-wise pairwise learning captures the local intrinsic relationship among EEG data. Third, a semi-supervised multi-domain adaptation is introduced to align the data representation among multiple domains (labeled source domain, unlabeled source domain, and target domain), where the distribution mismatch is alleviated. Extensive experiments are conducted on two benchmark databases (SEED and SEED-IV) under a cross-subject leave-one-subject-out cross-validation evaluation protocol. The results show the proposed EEGmatch performs better than the state-of-the-art methods under different incomplete label conditions (with 6.89% improvement on SEED and 1.44% improvement on SEED-IV), which demonstrates the effectiveness of the proposed EEGMatch in dealing with the label scarcity problem in emotion recognition using EEG signals. The source code is available at https://github.com/KAZABANA/EEGMatch.

eess.SP

Unsupervised Time-Aware Sampling Network with Deep Reinforcement Learning for EEG-Based Emotion Recognition

Recognizing human emotions from complex, multivariate, and non-stationary electroencephalography (EEG) time series is essential in affective brain-computer interface. However, because continuous labeling of ever-changing emotional states is not feasible in practice, existing methods can only assign a fixed label to all EEG timepoints in a continuous emotion-evoking trial, which overlooks the highly dynamic emotional states and highly non-stationary EEG signals. To solve the problems of high reliance on fixed labels and ignorance of time-changing information, in this paper we propose a time-aware sampling network (TAS-Net) using deep reinforcement learning (DRL) for unsupervised emotion recognition, which is able to detect key emotion fragments and disregard irrelevant and misleading parts. Extensive experiments are conducted on three public datasets (SEED, DEAP, and MAHNOB-HCI) for emotion recognition using leave-one-subject-out cross-validation, and the results demonstrate the superiority of the proposed method against previous unsupervised emotion recognition methods.

cs.HC

PR-PL: A Novel Transfer Learning Framework with Prototypical Representation based Pairwise Learning for EEG-Based Emotion Recognition

Affective brain-computer interfaces based on electroencephalography (EEG) is an important branch in the field of affective computing. However, individual differences and noisy labels seriously limit the effectiveness and generalizability of EEG-based emotion recognition models. In this paper, we propose a novel transfer learning framework with Prototypical Representation based Pairwise Learning (PR-PL) to learn discriminative and generalized prototypical representations for emotion revealing across individuals and formulate emotion recognition as pairwise learning for alleviating the reliance on precise label information. Extensive experiments are conducted on two benchmark databases under four cross-validation evaluation protocols (cross-subject cross-session, cross-subject within-session, within-subject cross-session, and within-subject within-session). The experimental results demonstrate the superiority of the proposed PR-PL against the state-of-the-arts under all four evaluation protocols, which shows the effectiveness and generalizability of PR-PL in dealing with the ambiguity of EEG responses in affective studies. The source code is available at https://github.com/KAZABANA/PR-PL.

cs.HC

EEGFuseNet: Hybrid Unsupervised Deep Feature Characterization and Fusion for High-Dimensional EEG with An Application to Emotion Recognition

How to effectively and efficiently extract valid and reliable features from high-dimensional electroencephalography (EEG), particularly how to fuse the spatial and temporal dynamic brain information into a better feature representation, is a critical issue in brain data analysis. Most current EEG studies work in a task driven manner and explore the valid EEG features with a supervised model, which would be limited by the given labels to a great extent. In this paper, we propose a practical hybrid unsupervised deep convolutional recurrent generative adversarial network based EEG feature characterization and fusion model, which is termed as EEGFuseNet. EEGFuseNet is trained in an unsupervised manner, and deep EEG features covering both spatial and temporal dynamics are automatically characterized. Comparing to the existing features, the characterized deep EEG features could be considered to be more generic and independent of any specific EEG task. The performance of the extracted deep and low-dimensional features by EEGFuseNet is carefully evaluated in an unsupervised emotion recognition application based on three public emotion databases. The results demonstrate the proposed EEGFuseNet is a robust and reliable model, which is easy to train and performs efficiently in the representation and fusion of dynamic EEG features. In particular, EEGFuseNet is established as an optimal unsupervised fusion model with promising cross-subject emotion recognition performance. It proves EEGFuseNet is capable of characterizing and fusing deep features that imply comparative cortical dynamic significance corresponding to the changing of different emotion states, and also demonstrates the possibility of realizing EEG based cross-subject emotion recognition in a pure unsupervised manner.

cs.HC