arXiv subjects

Linsui Deng

Publications and source records attributed to Linsui Deng.

4 recordsLinked to original sources

arXiv2026

A general framework for modeling Gaussian process with qualitative and quantitative factors

Computer experiments involving both qualitative and quantitative (QQ) factors have attracted increasing attention. Gaussian process (GP) models have proven effective in this context by choosing specialized covariance functions for QQ factors. In this work, we extend the latent variable-based GP approach, which maps qualitative factors into a continuous latent space, by establishing a general framework to apply standard kernel functions to continuous latent variables. This approach provides a novel perspective for interpreting some existing GP models for QQ factors and introduces new covariance structures in some situations. The ordinal structure can be incorporated naturally and seamlessly in this framework. Furthermore, the Bayesian information criterion and leave-one-out cross-validation are employed for model selection and model averaging. The performance of the proposed method is comprehensively studied on several examples.

stat.ME↗

arXiv2023

Joint Mirror Procedure: Controlling False Discovery Rate for Identifying Simultaneous Signals

In many applications, the process of identifying a specific feature of interest often involves testing multiple hypotheses for their joint statistical significance. Examples include mediation analysis which simultaneously examines the existence of the exposure-mediator and the mediator-outcome effects, and replicability analysis aiming to identify simultaneous signals that exhibit statistical significance across multiple independent experiments. In this study, we present a new approach called joint mirror (JM) procedure that effectively detects such features while maintaining false discovery rate (FDR) control in finite samples. The JM procedure employs an iterative method that gradually shrinks the rejection region based on progressively revealed information until a conservative estimate of the false discovery proportion (FDP) is below the target FDR level. Additionally, we introduce a more stringent error measure, known as the modified FDR (mFDR), which assigns weights to each false discovery based on its number of null components. We demonstrate that, under appropriate assumptions, the JM procedure controls the mFDR in finite samples. To implement the JM procedure, we propose an efficient algorithm that can incorporate partial ordering information. Through extensive simulations, we demonstrate that our procedure effectively controls the mFDR and enhances statistical power across various scenarios. Finally, we showcase the utility of our method by applying it to real-world mediation and replicability analyses.

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arXiv2022

Powerful Spatial Multiple Testing via Borrowing Neighboring Information

Clustered effects are often encountered in multiple hypothesis testing of spatial signals. In this paper, we propose a new method, termed \textit{two-dimensional spatial multiple testing} (2d-SMT) procedure, to control the false discovery rate (FDR) and improve the detection power by exploiting the spatial information encoded in neighboring observations. The proposed method provides a novel perspective of utilizing spatial information by gathering signal patterns and spatial dependence into an auxiliary statistic. 2d-SMT rejects the null when a primary statistic at the location of interest and the auxiliary statistic constructed based on nearby observations are greater than their corresponding cutoffs. 2d-SMT can also be combined with different variants of the weighted BH procedures to improve the detection power further. A fast algorithm is developed to accelerate the search for optimal cutoffs in 2d-SMT. In theory, we establish the asymptotic FDR control of 2d-SMT under weak spatial dependence. Extensive numerical experiments demonstrate that the 2d-SMT method combined with various weighted BH procedures achieves the most competitive performance in FDR and power trade-off.

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arXiv2022

Model-Free, Monotone Invariant and Computationally Efficient Feature Screening with Data-adaptive Threshold

Feature screening for ultrahigh-dimension, in general, proceeds with two essential steps. The first step is measuring and ranking the marginal dependence between response and covariates, and the second is determining the threshold. We develop a new screening procedure, called SIT-BY procedure, that possesses appealing statistical properties in both steps. By employing sliced independence estimates in the measuring and ranking stage, our proposed procedure requires no model assumptions, remains invariant to monotone transformation, and achieves almost linear computation complexity. Inspired by false discovery rate (FDR) control procedures, we offer a data-adaptive threshold benefit from the asymptotic normality of test statistics. Under moderate conditions, we demonstrate that our procedure can asymptotically control the FDR while maintaining the sure screening property. We investigate the finite sample performance of our proposed procedure via extensive simulations and an application to genome-wide dataset.

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