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Lior Weizman

Publications and source records attributed to Lior Weizman.

5 recordsLinked to original sources

Coupled Dictionary Learning for Multi-contrast MRI Reconstruction

Medical imaging tasks often involve multiple contrasts, such as T1- and T2-weighted magnetic resonance imaging (MRI) data. These contrasts capture information associated with the same underlying anatomy and thus exhibit similarities. In this paper, we propose a Coupled Dictionary Learning based multi-contrast MRI reconstruction (CDLMRI) approach to leverage an available guidance contrast to restore the target contrast. Our approach consists of three stages: coupled dictionary learning, coupled sparse denoising, and $k$-space consistency enforcing. The first stage learns a group of dictionaries that capture correlations among multiple contrasts. By capitalizing on the learned adaptive dictionaries, the second stage performs joint sparse coding to denoise the corrupted target image with the aid of a guidance contrast. The third stage enforces consistency between the denoised image and the measurements in the $k$-space domain. Numerical experiments on the retrospective under-sampling of clinical MR images demonstrate that incorporating additional guidance contrast via our design improves MRI reconstruction, compared to state-of-the-art approaches.

cs.CV

Compressed sensing for longitudinal MRI: An adaptive-weighted approach

Purpose: Repeated brain MRI scans are performed in many clinical scenarios, such as follow up of patients with tumors and therapy response assessment. In this paper, the authors show an approach to utilize former scans of the patient for the acceleration of repeated MRI scans. Methods: The proposed approach utilizes the possible similarity of the repeated scans in longitudinal MRI studies. Since similarity is not guaranteed, sampling and reconstruction are adjusted during acquisition to match the actual similarity between the scans. The baseline MR scan is utilized both in the sampling stage, via adaptive sampling, and in the reconstruction stage, with weighted reconstruction. In adaptive sampling, k-space sampling locations are optimized during acquisition. Weighted reconstruction uses the locations of the nonzero coefficients in the sparse domains as a prior in the recovery process. The approach was tested on 2D and 3D MRI scans of patients with brain tumors. Results: The longitudinal adaptive CS MRI (LACS-MRI) scheme provides reconstruction quality which outperforms other CS-based approaches for rapid MRI. Examples are shown on patients with brain tumors and demonstrate improved spatial resolution. Compared with data sampled at Nyquist rate, LACS-MRI exhibits Signal-to-Error Ratio (SER) of 24.8dB with undersampling factor of 16.6 in 3D MRI. Conclusions: The authors have presented a novel method for image reconstruction utilizing similarity of scans in longitudinal MRI studies, where possible. The proposed approach can play a major part and significantly reduce scanning time in many applications that consist of disease follow-up and monitoring of longitudinal changes in brain MRI.

physics.med-ph

Reference-Based MRI

Purpose: In many clinical MRI scenarios, existing imaging information can be used to significantly shorten acquisition time or to improve Signal to Noise Ratio (SNR). In this paper the authors present a framework for fast MRI by exploiting a reference image (FASTMER). Methods: The proposed approach utilizes the possible similarity of the reference image that exists in many clinical MRI imaging scenarios. Such scenarios include similarity between adjacent slices in high resolution MRI, similarity between various contrasts in the same scan and similarity between different scans of the same patient. The authors take into account that the reference image may exhibit low similarity with the acquired image and develop an iterative weighted approach for reconstruction, which tunes the weights according to the degree of similarity. Results: Experimental results demonstrate the performance of the method in three different clinical MRI scenarios: SNR improvement in high resolution brain MRI, exploiting similarity between T2-weighted and fluid-attenuated inversion recovery (FLAIR) for fast FLAIR scanning and utilizing similarity between baseline and follow-up scans for fast follow-up. Results outperform reconstruction results of existing state-of-the-art methods. Conclusions: The authors present a method for fast MRI by exploiting a reference image. The method is based on an iterative reconstruction approach that supports cases in which similarity to the reference scan is not guaranteed, which enables the applicability of the method to a variety of MRI applications. Thanks to the existence of reference images in various clinical imaging scenarios, the proposed framework can play a major part in improving reconstruction in many MR applications.

physics.med-ph

Low Rank Magnetic Resonance Fingerprinting

Purpose: Magnetic Resonance Fingerprinting (MRF) is a relatively new approach that provides quantitative MRI measures using randomized acquisition. Extraction of physical quantitative tissue parameters is performed off-line, without the need of patient presence, based on acquisition with varying parameters and a dictionary generated according to the Bloch equation simulations. MRF uses hundreds of radio frequency (RF) excitation pulses for acquisition, and therefore a high undersampling ratio in the sampling domain (k-space) is required for reasonable scanning time. This undersampling causes spatial artifacts that hamper the ability to accurately estimate the tissue's quantitative values. In this work, we introduce a new approach for quantitative MRI using MRF, called magnetic resonance Fingerprinting with LOw Rank (FLOR). Methods: We exploit the low rank property of the concatenated temporal imaging contrasts, on top of the fact that the MRF signal is sparsely represented in the generated dictionary domain. We present an iterative scheme that consists of a gradient step followed by a low rank projection using the singular value decomposition. Results: Experimental results consist of retrospective sampling, that allows comparison to a well defined reference, and prospective sampling that shows the performance of FLOR for a real-data sampling scenario. Both experiments demonstrate improved parameter accuracy compared to other compressed-sensing and low-rank based methods for MRF at 5% and 9% sampling ratios, for the retrospective and prospective experiments, respectively. Conclusions: We have shown through retrospective and prospective experiments that by exploiting the low rank nature of the MRF signal, FLOR recovers the MRF temporal undersampled images and provides more accurate parameter maps compared to previous iterative methods.

physics.med-ph

PEAR: PEriodic And fixed Rank separation for fast fMRI

In functional MRI (fMRI), faster acquisition via undersampling of data can improve the spatial-temporal resolution trade-off and increase statistical robustness through increased degrees-of-freedom. High quality reconstruction of fMRI data from undersampled measurements requires proper modeling of the data. We present an fMRI reconstruction approach based on modeling the fMRI signal as a sum of periodic and fixed rank components, for improved reconstruction from undersampled measurements. We decompose the fMRI signal into a component which a has fixed rank and a component consisting of a sum of periodic signals which is sparse in the temporal Fourier domain. Data reconstruction is performed by solving a constrained problem that enforces a fixed, moderate rank on one of the components, and a limited number of temporal frequencies on the other. Our approach is coined PEAR - PEriodic And fixed Rank separation for fast fMRI. Experimental results include purely synthetic simulation, a simulation with real timecourses and retrospective undersampling of a real fMRI dataset. Evaluation was performed both quantitatively and visually versus ground truth, comparing PEAR to two additional recent methods for fMRI reconstruction from undersampled measurements. Results demonstrate PEAR's improvement in estimating the timecourses and activation maps versus the methods compared against at acceleration ratios of R=8,16 (for simulated data) and R=6.66,10 (for real data). PEAR results in reconstruction with higher fidelity than when using a fixed-rank based model or a conventional Low-rank+Sparse algorithm. We have shown that splitting the functional information between the components leads to better modeling of fMRI, over state-of-the-art methods.

physics.med-ph