arXiv subjects

Lirong Zheng

Publications and source records attributed to Lirong Zheng.

16 recordsLinked to original sources

arXiv2026

Generalizable 6D Pose Estimation of Textureless Objects with Planar-based Gaussian Splatting

Estimating the 6D pose of textureless objects without prior CAD models remains a critical challenge due to the lack of appearance features. While recent generalizable approaches alleviate the dependence on object-specific models, their performance on low-texture objects is often limited by insufficient geometric constraints in the underlying representations. In this work, we propose PG-Pose, a geometry-aware framework combining Planar-based Gaussian Splatting (PGS) reconstruction and Geometry-driven pose optimization. In the offline representation extraction stage, three distinct representations of the object are extracted from multi-view reference RGB images with known poses. PG-Pose reconstructs a 3D Gaussian representation and renders high-fidelity depth maps to generate 3D point clouds through back projection. In the online pose inference stage, the initial pose of the input image is estimated by 2D-3D correspondence matching between the input image and the reconstructed 3D point clouds, followed by a PGS-Refiner for iterative pose optimization. Evaluations on the OnePose-LowTexture datasets, PG-Pose achieves an average accuracy of 94.2% ADD(S)@0.1d, with a 2.1% improvement average accuracy compared with the state-of-the-art (SOTA) GS-based approach. To further demonstrate the effectiveness of PG-Pose for industrial robots in grasping tasks, we deploy it on a dual-arm industrial robot and successfully realize the grasping task on an unseen object.

cs.RO↗

arXiv2026

MxGLUT: A Reconfigurable LUT-Centric Broadcast Dataflow Accelerator for Mixed-Precision GEMM

Large language model (LLM) inference suffers from growing inefficiency across the prefill and decode phases, especially under weight-only quantization, where activations remain in FP8 while weights are compressed to low-bit integers. Existing LUT-based accelerators mainly target FP8-INT4 computation and still rely on separate floating-point (FP) datapaths for attention GEMM operations, leading to redundant hardware and non-unified mixed-precision execution. Moreover, their static dataflows are poorly matched to the distinct prefill and decode phases. To address these challenges, we propose MxGLUT, a reconfigurable LUT-centric broadcast (RLB) dataflow accelerator built on mixed-precision LUT-based processing elements (MxLPEs). Guided by a unified LUT-based execution framework, MxGLUT organizes both FP8-INT4 and FP8-FP8 GEMMs under a single LUT-based compute mechanism without dedicated FP multipliers or additional FP datapaths, and further adopts the RLB dataflow that localizes heavy partial-sum accumulation during the prefill phase and exploits weight reuse in the decode phase. Synthesized in UMC $28\,\mathrm{nm}$ CMOS at $200~\mathrm{MHz}$, MxGLUT reduces multiplier area by up to $56.92\%$ and power by up to $77.07\%$ and $78.35\%$ in FP8-INT4 and FP8-FP8 modes, respectively. At the accelerator level, MxGLUT achieves an area efficiency of $0.492~\mathrm{TFLOPS/mm^2}$ and an energy efficiency of $11.58~\mathrm{TFLOPS/W}$, while adding native FP8-FP8 support incurs only $2.57\%$ and $3.34\%$ reductions in area and energy efficiency, respectively, relative to the FP8-INT4-only FIGLUT baseline. Across the Llama family, MxGLUT achieves up to $2.16\times$ and $1.49\times$ latency speedup, and reduces normalized energy to $0.44\times$ and $0.71\times$ in prefill and decode, respectively, with at most $1.70\%$ perplexity increase.

cs.AR↗

arXiv2026

A Graph Neural Network-Based Approach to XANES Data Analysis

X-ray absorption spectroscopy (XAS) is an indispensable tool to characterize the atomic-scale three-dimensional local structure of the system, in which XANES is the most important energy region to reflect the three-dimensional structure. However quantitative analysis of three-dimensional structure from XANES requires users to have a deep understanding and accurate judgment of structural information and summarize several structural parameters, which is often difficult to achieve. In this work, We construct \textbf{physics-informed Graph neural network} and \textbf{Transformer} models for calculating XANES from the input three-dimensional structure; we improve the efficiency of the model based on the physical meaning of XAS; then we combine the model and optimization algorithm to fit the three-dimensional structure of given system. This method does not require users to summarize the structural parameters, has wide application range. It can be applied to the three-dimensional structure analysis of solid materials and has positive significance for the study of structure-function relationship in the fields of energy and catalysis. In addition, this method is expected to be developed into an online three-dimensional structure analysis method for XAS related beamlines.

physics.chem-ph↗

arXiv2026

Efficient Dual-domain Image Dehazing with Haze Prior Perception

Transformers offer strong global modeling for single-image dehazing but come with high computational costs. Most methods rely on spatial features to capture long-range dependencies, making them less effective under complex haze conditions. Although some integrate frequency-domain cues, weak coupling between spatial and frequency branches limits their performance. To address these issues, we propose the Dark Channel Guided Frequency-aware Dehazing Network (DGFDNet), a dual-domain framework that explicitly aligns degradation across spatial and frequency domains. At its core, the DGFDBlock consists of two key modules: 1) Haze-Aware Frequency Modulator (HAFM), which uses dark channel priors to generate a haze confidence map for adaptive frequency modulation, achieving global degradation-aware spectral filtering. 2) Multi-level Gating Aggregation Module (MGAM), which fuses multi-scale features via multi-scale convolutions and a hybrid gating mechanism to recover fine-grained structures. Additionally, the Prior Correction Guidance Branch (PCGB) incorporates feedback for iterative refinement of the prior, improving haze localization accuracy, particularly in outdoor scenes. Extensive experiments on four benchmark datasets demonstrate that DGFDNet achieves state-of-the-art performance with improved robustness and real-time efficiency. Code is available at: https://github.com/Dilizlr/DGFDNet.

cs.CV↗

arXiv2026

Fourier-RWKV: A Multi-State Perception Network for Efficient Image Dehazing

Image dehazing is crucial for reliable visual perception, yet it remains highly challenging under real-world non-uniform haze conditions. Although Transformer-based methods excel at capturing global context, their quadratic computational complexity hinders real-time deployment. To address this, we propose Fourier Receptance Weighted Key Value (Fourier-RWKV), a novel dehazing framework based on a Multi-State Perception paradigm. The model achieves comprehensive haze degradation modeling with linear complexity by synergistically integrating three distinct perceptual states: (1) Spatial-form Perception, realized through the Deformable Quad-directional Token Shift (DQ-Shift) operation, which dynamically adjusts receptive fields to accommodate local haze variations; (2) Frequency-domain Perception, implemented within the Fourier Mix block, which extends the core WKV attention mechanism of RWKV from the spatial domain to the Fourier domain, preserving the long-range dependencies essential for global haze estimation while mitigating spatial attenuation; (3) Semantic-relation Perception, facilitated by the Semantic Bridge Module (SBM), which utilizes Dynamic Semantic Kernel Fusion (DSK-Fusion) to precisely align encoder-decoder features and suppress artifacts. Extensive experiments on multiple benchmarks demonstrate that Fourier-RWKV delivers state-of-the-art performance across diverse haze scenarios while significantly reducing computational overhead, establishing a favorable trade-off between restoration quality and practical efficiency. Code is available at: https://github.com/Dilizlr/Fourier-RWKV.

cs.CV↗

arXiv2024

Pro-PRIME: A general Temperature-Guided Language model to engineer enhanced Stability and Activity in Proteins

Designing protein mutants of both high stability and activity is a critical yet challenging task in protein engineering. Here, we introduce PRIME, a deep learning model, which can suggest protein mutants of improved stability and activity without any prior experimental mutagenesis data of the specified protein. Leveraging temperature-aware language modeling, PRIME demonstrated superior predictive power compared to current state-of-the-art models on the public mutagenesis dataset over 283 protein assays. Furthermore, we validated PRIME's predictions on five proteins, examining the top 30-45 single-site mutations' impact on various protein properties, including thermal stability, antigen-antibody binding affinity, and the ability to polymerize non-natural nucleic acid or resilience to extreme alkaline conditions. Remarkably, over 30% of the AI-recommended mutants exhibited superior performance compared to their pre-mutation counterparts across all proteins and desired properties. Moreover, we have developed an efficient, and successful method based on PRIME to rapidly obtain multi-site mutants with enhanced activity and stability. Hence, PRIME demonstrates the general applicability in protein engineering.

q-bio.BM↗

arXiv2024

Secondary Structure-Guided Novel Protein Sequence Generation with Latent Graph Diffusion

The advent of deep learning has introduced efficient approaches for de novo protein sequence design, significantly improving success rates and reducing development costs compared to computational or experimental methods. However, existing methods face challenges in generating proteins with diverse lengths and shapes while maintaining key structural features. To address these challenges, we introduce CPDiffusion-SS, a latent graph diffusion model that generates protein sequences based on coarse-grained secondary structural information. CPDiffusion-SS offers greater flexibility in producing a variety of novel amino acid sequences while preserving overall structural constraints, thus enhancing the reliability and diversity of generated proteins. Experimental analyses demonstrate the significant superiority of the proposed method in producing diverse and novel sequences, with CPDiffusion-SS surpassing popular baseline methods on open benchmarks across various quantitative measurements. Furthermore, we provide a series of case studies to highlight the biological significance of the generation performance by the proposed method. The source code is publicly available at https://github.com/riacd/CPDiffusion-SS

cs.AI↗

arXiv2024

Protein Representation Learning with Sequence Information Embedding: Does it Always Lead to a Better Performance?

Deep learning has become a crucial tool in studying proteins. While the significance of modeling protein structure has been discussed extensively in the literature, amino acid types are typically included in the input as a default operation for many inference tasks. This study demonstrates with structure alignment task that embedding amino acid types in some cases may not help a deep learning model learn better representation. To this end, we propose ProtLOCA, a local geometry alignment method based solely on amino acid structure representation. The effectiveness of ProtLOCA is examined by a global structure-matching task on protein pairs with an independent test dataset based on CATH labels. Our method outperforms existing sequence- and structure-based representation learning methods by more quickly and accurately matching structurally consistent protein domains. Furthermore, in local structure pairing tasks, ProtLOCA for the first time provides a valid solution to highlight common local structures among proteins with different overall structures but the same function. This suggests a new possibility for using deep learning methods to analyze protein structure to infer function.

q-bio.QM↗

arXiv2024

Simple, Efficient and Scalable Structure-aware Adapter Boosts Protein Language Models

Fine-tuning Pre-trained protein language models (PLMs) has emerged as a prominent strategy for enhancing downstream prediction tasks, often outperforming traditional supervised learning approaches. As a widely applied powerful technique in natural language processing, employing Parameter-Efficient Fine-Tuning techniques could potentially enhance the performance of PLMs. However, the direct transfer to life science tasks is non-trivial due to the different training strategies and data forms. To address this gap, we introduce SES-Adapter, a simple, efficient, and scalable adapter method for enhancing the representation learning of PLMs. SES-Adapter incorporates PLM embeddings with structural sequence embeddings to create structure-aware representations. We show that the proposed method is compatible with different PLM architectures and across diverse tasks. Extensive evaluations are conducted on 2 types of folding structures with notable quality differences, 9 state-of-the-art baselines, and 9 benchmark datasets across distinct downstream tasks. Results show that compared to vanilla PLMs, SES-Adapter improves downstream task performance by a maximum of 11% and an average of 3%, with significantly accelerated training speed by a maximum of 1034% and an average of 362%, the convergence rate is also improved by approximately 2 times. Moreover, positive optimization is observed even with low-quality predicted structures. The source code for SES-Adapter is available at https://github.com/tyang816/SES-Adapter.

cs.CL↗

arXiv2023

A Unified View on Neural Message Passing with Opinion Dynamics for Social Networks

Social networks represent a common form of interconnected data frequently depicted as graphs within the domain of deep learning-based inference. These communities inherently form dynamic systems, achieving stability through continuous internal communications and opinion exchanges among social actors along their social ties. In contrast, neural message passing in deep learning provides a clear and intuitive mathematical framework for understanding information propagation and aggregation among connected nodes in graphs. Node representations are dynamically updated by considering both the connectivity and status of neighboring nodes. This research harmonizes concepts from sociometry and neural message passing to analyze and infer the behavior of dynamic systems. Drawing inspiration from opinion dynamics in sociology, we propose ODNet, a novel message passing scheme incorporating bounded confidence, to refine the influence weight of local nodes for message propagation. We adjust the similarity cutoffs of bounded confidence and influence weights of ODNet and define opinion exchange rules that align with the characteristics of social network graphs. We show that ODNet enhances prediction performance across various graph types and alleviates oversmoothing issues. Furthermore, our approach surpasses conventional baselines in graph representation learning and proves its practical significance in analyzing real-world co-occurrence networks of metabolic genes. Remarkably, our method simplifies complex social network graphs solely by leveraging knowledge of interaction frequencies among entities within the system. It accurately identifies internal communities and the roles of genes in different metabolic pathways, including opinion leaders, bridge communicators, and isolators.

cs.SI↗

arXiv2023

Factor Decomposed Generative Adversarial Networks for Text-to-Image Synthesis

Prior works about text-to-image synthesis typically concatenated the sentence embedding with the noise vector, while the sentence embedding and the noise vector are two different factors, which control the different aspects of the generation. Simply concatenating them will entangle the latent factors and encumber the generative model. In this paper, we attempt to decompose these two factors and propose Factor Decomposed Generative Adversarial Networks~(FDGAN). To achieve this, we firstly generate images from the noise vector and then apply the sentence embedding in the normalization layer for both generator and discriminators. We also design an additive norm layer to align and fuse the text-image features. The experimental results show that decomposing the noise and the sentence embedding can disentangle latent factors in text-to-image synthesis, and make the generative model more efficient. Compared with the baseline, FDGAN can achieve better performance, while fewer parameters are used.

cs.MM↗

arXiv2023

Time-frequency Network for Robust Speaker Recognition

The wide deployment of speech-based biometric systems usually demands high-performance speaker recognition algorithms. However, most of the prior works for speaker recognition either process the speech in the frequency domain or time domain, which may produce suboptimal results because both time and frequency domains are important for speaker recognition. In this paper, we attempt to analyze the speech signal in both time and frequency domains and propose the time-frequency network~(TFN) for speaker recognition by extracting and fusing the features in the two domains. Based on the recent advance of deep neural networks, we propose a convolution neural network to encode the raw speech waveform and the frequency spectrum into domain-specific features, which are then fused and transformed into a classification feature space for speaker recognition. Experimental results on the publicly available datasets TIMIT and LibriSpeech show that our framework is effective to combine the information in the two domains and performs better than the state-of-the-art methods for speaker recognition.

cs.SD↗

arXiv2022

A Ligand-and-structure Dual-driven Deep Learning Method for the Discovery of Highly Potent GnRH1R Antagonist to treat Uterine Diseases

Gonadotrophin-releasing hormone receptor (GnRH1R) is a promising therapeutic target for the treatment of uterine diseases. To date, several GnRH1R antagonists are available in clinical investigation without satisfying multiple property constraints. To fill this gap, we aim to develop a deep learning-based framework to facilitate the effective and efficient discovery of a new orally active small-molecule drug targeting GnRH1R with desirable properties. In the present work, a ligand-and-structure combined model, namely LS-MolGen, was firstly proposed for molecular generation by fully utilizing the information on the known active compounds and the structure of the target protein, which was demonstrated by its superior performance than ligand- or structure-based methods separately. Then, a in silico screening including activity prediction, ADMET evaluation, molecular docking and FEP calculation was conducted, where ~30,000 generated novel molecules were narrowed down to 8 for experimental synthesis and validation. In vitro and in vivo experiments showed that three of them exhibited potent inhibition activities (compound 5 IC50 = 0.856 nM, compound 6 IC50 = 0.901 nM, compound 7 IC50 = 2.54 nM) against GnRH1R, and compound 5 performed well in fundamental PK properties, such as half-life, oral bioavailability, and PPB, etc. We believed that the proposed ligand-and-structure combined molecular generative model and the whole computer-aided workflow can potentially be extended to similar tasks for de novo drug design or lead optimization.

q-bio.BM↗

arXiv2021

T-Net: Deep Stacked Scale-Iteration Network for Image Dehazing

Hazy images reduce the visibility of the image content, and haze will lead to failure in handling subsequent computer vision tasks. In this paper, we address the problem of image dehazing by proposing a dehazing network named T-Net, which consists of a backbone network based on the U-Net architecture and a dual attention module. And it can achieve multi-scale feature fusion by using skip connections with a new fusion strategy. Furthermore, by repeatedly unfolding the plain T-Net, Stack T-Net is proposed to take advantage of the dependence of deep features across stages via a recursive strategy. In order to reduce network parameters, the intra-stage recursive computation of ResNet is adopted in our Stack T-Net. And we take both the stage-wise result and the original hazy image as input to each T-Net and finally output the prediction of clean image. Experimental results on both synthetic and real-world images demonstrate that our plain T-Net and the advanced Stack T-Net perform favorably against the state-of-the-art dehazing algorithms, and show that our Stack T-Net could further improve the dehazing effect, demonstrating the effectiveness of the recursive strategy.

cs.CV↗

arXiv2017

A Low-Power Accelerator for Deep Neural Networks with Enlarged Near-Zero Sparsity

It remains a challenge to run Deep Learning in devices with stringent power budget in the Internet-of-Things. This paper presents a low-power accelerator for processing Deep Neural Networks in the embedded devices. The power reduction is realized by avoiding multiplications of near-zero valued data. The near-zero approximation and a dedicated Near-Zero Approximation Unit (NZAU) are proposed to predict and skip the near-zero multiplications under certain thresholds. Compared with skipping zero-valued computations, our design achieves 1.92X and 1.51X further reduction of the total multiplications in LeNet-5 and Alexnet respectively, with negligible lose of accuracy. In the proposed accelerator, 256 multipliers are grouped into 16 independent Processing Lanes (PL) to support up to 16 neuron activations simultaneously. With the help of data pre-processing and buffering in each PL, multipliers can be clock-gated in most of the time even the data is excessively streaming in. Designed and simulated in UMC 65 nm process, the accelerator operating at 500 MHz is $>$ 4X faster than the mobile GPU Tegra K1 in processing the fully-connected layer FC8 of Alexnet, while consuming 717X less energy.

cs.AR↗

arXiv2010

Evidence for Competition between Superconductivity and Kondo Effect in CeFeAsO0.7F0.3 under High Pressure

We discover a pressure induced quantum phase transition from the superconducting state to the non-superconducting Kondo screened phase associated with a 2% volume collapse in CeFeAsO0.7F0.3 through measurements of high-pressure resistance, synchrotron x-ray diffraction, and x-ray absorption spectroscopy (XAS) in a diamond anvil cell. Our XAS data of Ce-L3 in CeFeAsO0.7F0.3 clearly show a spectral weight transfer from the main line to the satellite line after the transition, demonstrating the formation of the Kondo singlets under pressure in CeFeAsO1-xFx. Our results have revealed a physical picture of a pressure-induce competition between Kondo singlets and BCS singlets in the Ce-pnictide superconductors.

cond-mat.supr-con↗