arXiv subjects

Liyuan Sun

Publications and source records attributed to Liyuan Sun.

6 recordsLinked to original sources

arXiv2026

SkinGPT-X: A Self-Evolving Collaborative Multi-Agent System for Transparent and Trustworthy Dermatological Diagnosis

While recent advancements in Large Language Models have significantly advanced dermatological diagnosis, monolithic LLMs frequently struggle with fine-grained, large-scale multi-class diagnostic tasks and rare skin disease diagnosis owing to training data sparsity, while also lacking the interpretability and traceability essential for clinical reasoning. Although multi-agent systems can offer more transparent and explainable diagnostics, existing frameworks are primarily concentrated on Visual Question Answering and conversational tasks, and their heavy reliance on static knowledge bases restricts adaptability in complex real-world clinical settings. Here, we present SkinGPT-X, a multimodal collaborative multi-agent system for dermatological diagnosis integrated with a self-evolving dermatological memory mechanism. By simulating the diagnostic workflow of dermatologists and enabling continuous memory evolution, SkinGPT-X delivers transparent and trustworthy diagnostics for the management of complex and rare dermatological cases. To validate the robustness of SkinGPT-X, we design a three-tier comparative experiment. First, we benchmark SkinGPT-X against four state-of-the-art LLMs across four public datasets, demonstrating its state-of-the-art performance with a +9.6% accuracy improvement on DDI31 and +13% weighted F1 gain on Dermnet over the state-of-the-art model. Second, we construct a large-scale multi-class dataset covering 498 distinct dermatological categories to evaluate its fine-grained classification capabilities. Finally, we curate the rare skin disease dataset, the first benchmark to address the scarcity of clinical rare skin diseases which contains 564 clinical samples with eight rare dermatological diseases. On this dataset, SkinGPT-X achieves a +9.8% accuracy improvement, a +7.1% weighted F1 improvement, a +10% Cohen's Kappa improvement.

cs.CV↗

arXiv2025

Trustworthy and Fair SkinGPT-R1 for Democratizing Dermatological Reasoning across Diverse Ethnicities

The clinical translation of dermatological AI is hindered by opaque reasoning and systematic performance disparities across skin tones. Here we present SkinGPT-R1, a multimodal large language model that integrates chain-of-thought diagnostic reasoning with a fairness-aware mixture-of-experts architecture for interpretable and equitable skin disease diagnosis. Through parameter-efficient adaptation of a frozen reasoning backbone, SkinGPT-R1 generates structured diagnostic reports comprising visual findings, differential reasoning, and final diagnosis. Across seven external datasets spanning diverse pathologies and imaging conditions, SkinGPT-R1 achieves state-of-the-art accuracy on six benchmarks, including 82.50\% on a challenging 40-class long-tail classification task (+19.30\% over leading baselines). Blinded evaluation by five board-certified dermatologists on 1,000 phenotypically balanced cases yields a mean score of 3.6 out of 5, with the highest ratings in safety (3.8) and reasoning coherence (3.6), indicating that the generated rationales are clinically safe, logically grounded, and suitable for supporting diagnostic decision-making. Critically, SkinGPT-R1 mitigates algorithmic bias across the full Fitzpatrick spectrum, achieving a robust worst-group performance of 41.40\% on the Fitz17k benchmark and a five-fold relative improvement in lower-bound accuracy on the DDI dataset compared to standard multimodal baselines. These results establish a framework for trustworthy, fair, and explainable AI-assisted dermatological diagnosis.

cs.CV↗

arXiv2024

SkinCaRe: A Multimodal Dermatology Dataset Annotated with Medical Caption and Chain-of-Thought Reasoning

With the widespread application of artificial intelligence (AI), particularly deep learning (DL) and vision large language models (VLLMs), in skin disease diagnosis, the need for interpretability becomes crucial. However, existing dermatology datasets are limited in their inclusion of concept-level meta-labels, and none offer rich medical descriptions in natural language. This deficiency impedes the advancement of LLM-based methods in dermatologic diagnosis. To address this gap and provide a meticulously annotated dermatology dataset with comprehensive natural language descriptions, we introduce \textbf{SkinCaRe}, a comprehensive multimodal resource that unifies \textit{SkinCAP} and \textit{SkinCoT}. \textbf{SkinCAP} comprises 4,000 images sourced from the Fitzpatrick 17k skin disease dataset and the Diverse Dermatology Images dataset, annotated by board-certified dermatologists to provide extensive medical descriptions and captions. In addition, we introduce \textbf{SkinCoT}, a curated dataset pairing 3,041 dermatologic images with clinician-verified, hierarchical chain-of-thought (CoT) diagnoses. Each diagnostic narrative is rigorously evaluated against six quality criteria and iteratively refined until it meets a predefined standard of clinical accuracy and explanatory depth. Together, SkinCAP (captioning) and SkinCoT (reasoning), collectively referred to as SkinCaRe, encompass 7,041 expertly curated dermatologic cases and provide a unified and trustworthy resource for training multimodal models that both describe and explain dermatologic images. SkinCaRe is publicly available at https://huggingface.co/datasets/yuhos16/SkinCaRe.

cs.CV↗

arXiv2023

SkinGPT-4: An Interactive Dermatology Diagnostic System with Visual Large Language Model

Skin and subcutaneous diseases rank high among the leading contributors to the global burden of nonfatal diseases, impacting a considerable portion of the population. Nonetheless, the field of dermatology diagnosis faces three significant hurdles. Firstly, there is a shortage of dermatologists accessible to diagnose patients, particularly in rural regions. Secondly, accurately interpreting skin disease images poses a considerable challenge. Lastly, generating patient-friendly diagnostic reports is usually a time-consuming and labor-intensive task for dermatologists. To tackle these challenges, we present SkinGPT-4, which is the world's first interactive dermatology diagnostic system powered by an advanced visual large language model. SkinGPT-4 leverages a fine-tuned version of MiniGPT-4, trained on an extensive collection of skin disease images (comprising 52,929 publicly available and proprietary images) along with clinical concepts and doctors' notes. We designed a two-step training process to allow SkinGPT to express medical features in skin disease images with natural language and make accurate diagnoses of the types of skin diseases. With SkinGPT-4, users could upload their own skin photos for diagnosis, and the system could autonomously evaluate the images, identifies the characteristics and categories of the skin conditions, performs in-depth analysis, and provides interactive treatment recommendations. Meanwhile, SkinGPT-4's local deployment capability and commitment to user privacy also render it an appealing choice for patients in search of a dependable and precise diagnosis of their skin ailments. To demonstrate the robustness of SkinGPT-4, we conducted quantitative evaluations on 150 real-life cases, which were independently reviewed by certified dermatologists, and showed that SkinGPT-4 could provide accurate diagnoses of skin diseases.

eess.IV↗

arXiv2021

Collaborative Teacher-Student Learning via Multiple Knowledge Transfer

Knowledge distillation (KD), as an efficient and effective model compression technique, has been receiving considerable attention in deep learning. The key to its success is to transfer knowledge from a large teacher network to a small student one. However, most of the existing knowledge distillation methods consider only one type of knowledge learned from either instance features or instance relations via a specific distillation strategy in teacher-student learning. There are few works that explore the idea of transferring different types of knowledge with different distillation strategies in a unified framework. Moreover, the frequently used offline distillation suffers from a limited learning capacity due to the fixed teacher-student architecture. In this paper we propose a collaborative teacher-student learning via multiple knowledge transfer (CTSL-MKT) that prompts both self-learning and collaborative learning. It allows multiple students learn knowledge from both individual instances and instance relations in a collaborative way. While learning from themselves with self-distillation, they can also guide each other via online distillation. The experiments and ablation studies on four image datasets demonstrate that the proposed CTSL-MKT significantly outperforms the state-of-the-art KD methods.

cs.LG↗

arXiv2014

On the duration and intensity of cumulative advantage competitions

The role of skill (fitness) and luck (randomness) as driving forces on the dynamics of resource accumulation in a myriad of systems have long puzzled scientists. Fueled by undisputed inequalities that emerge from actual competitions, there is a pressing need for better understanding the effects of skill and luck in resource accumulation. When such competitions are driven by externalities such as cumulative advantage (CA), the rich-get-richer effect, little is known with respect to fundamental properties such as their duration and intensity. In this work we provide a mathematical understanding of how CA exacerbates the role of luck in detriment of skill in simple and well-studied competition models. We show, for instance, that if two agents are competing for resources that arrive sequentially at each time unit, an early stroke of luck can place the less skilled in the lead for an extremely long period of time, a phenomenon we call "struggle of the fittest". In the absence of CA, the more skilled quickly prevails despite any early stroke of luck that the less skilled may have. We prove that duration of a simple skill and luck competition model exhibit power law tails when CA is present, regardless of skill difference, which is in sharp contrast to exponential tails when CA is absent. Our findings have important implications to competitions not only in complex social systems but also in contexts that leverage such models.

physics.soc-ph↗