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Loes Crielaard

Publications and source records attributed to Loes Crielaard.

2 recordsLinked to original sources

Diagrams-to-Dynamics (D2D): Exploring Causal Loop Diagram Leverage Points under Uncertainty

Background: Causal loop diagrams (CLDs) are widely used in health and environmental research to represent hypothesized causal structures underlying complex problems. However, as qualitative and static representations, CLDs are limited in their ability to support dynamic analysis and inform intervention strategies. We propose Diagrams-to-Dynamics (D2D), a method for converting CLDs into exploratory system dynamics models in the absence of empirical data. With minimal user input - following a protocol to label variables as stocks, flows or auxiliaries, and constants - D2D utilizes the structural information already encoded in CLDs, namely the existence and polarity of causal connections, to simulate hypothetical interventions and explore potentially influential places to intervene, known as 'leverage points,' under uncertainty. Results: D2D helps distinguish between high- and low-ranked leverage points. We compare D2D to a calibrated system dynamics model constructed from the same CLD and variable labels. D2D showed greater consistency with the calibrated model than did static network centrality analysis, while also providing uncertainty estimates and guidance for future data collection. Conclusions: The D2D method is implemented in an open-source Python package and a web-based application to support further testing and to lower the barrier to dynamic modeling for researchers working with CLDs. Future studies could help establish the approach's utility across a broad range of cases and domains.

cs.LG

Inferring temporal dynamics from cross-sectional data using Langevin dynamics

Cross-sectional studies are widely prevalent since they are more feasible to conduct compared to longitudinal studies. However, cross-sectional data lack the temporal information required to study the evolution of the underlying processes. Nevertheless, this is essential to develop predictive computational models which is the first step towards causal modelling. We propose a method for inferring computational models from cross-sectional data using Langevin dynamics. This method can be applied to any system that can be described as effectively following a free energy landscape, such as protein folding, stem cell differentiation and reprogramming, and social systems involving human interaction and social norms. A crucial assumption in our method is that the data-points are gathered from a system in (local) equilibrium. The result is a set of stochastic differential equations which capture the temporal dynamics, by assuming that groups of data-points are subject to the same free energy landscape and amount of noise. Our method is a 'baseline' method which initiates the development of computational models which can be iteratively enhanced through the inclusion of expert knowledge. We validate the proposed method against two population-based longitudinal datasets and observe significant predictive power in comparison with random choice algorithms. We also show how the predictive power of our 'baseline' model can be enhanced by incorporating domain expert knowledge. Our method addresses an important obstacle for model development in fields dominated by cross-sectional datasets.

cs.CE