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Lore Depuydt

Publications and source records attributed to Lore Depuydt.

4 recordsLinked to original sources

KeBaB: $k$-mer based breaking for finding long MEMs

Long maximal exact matches (MEMs) are used in many genomics applications such as read classification and sequence alignment. Li's ropebwt3 finds long MEMs quickly because it can often ignore much of its input. In this paper we show that a fast and space efficient $k$-mer filtration step using a Bloom filter speeds up MEM-finders such as ropebwt3 even further by letting them ignore even more. We also show experimentally that our approach can accelerate metagenomic classification without significantly hurting accuracy.

cs.DS

Suffixient Arrays: a New Efficient Suffix Array Compression Technique

The Suffix Array is a classic text index enabling on-line pattern matching queries via simple binary search. The main drawback of the Suffix Array is that it takes linear space in the text's length, even if the text itself is extremely compressible. Several works in the literature showed that the Suffix Array can be compressed, but they all rely on complex succinct data structures which in practice tend to exhibit poor cache locality and thus significantly slow down queries. In this paper, we propose a new simple and very efficient solution to this problem by presenting the \emph{Suffixient Array}: a tiny subset of the Suffix Array \emph{sufficient} to locate on-line one pattern occurrence (in general, all its Maximal Exact Matches) via binary search, provided that random access to the text is available. We prove that: (i) the Suffixient Array length $χ$ is a strong repetitiveness measure, (ii) unlike most existing repetition-aware indexes such as the $r$-index, our new index is efficient in the I/O model, and (iii) Suffixient Arrays can be computed in linear time and compressed working space. We show experimentally that, when using well-established compressed random access data structures on repetitive collections, the Suffixient Array $\SuA$ is \emph{simultaneously} (i) faster and orders of magnitude smaller than the Suffix Array $\SA$ and (ii) smaller and \emph{one to two orders of magnitude faster} than the $r$-index. With an average pattern matching query time as low as 3.5 ns per character, our new index gets very close to the ultimate lower bound: the RAM throughput of our workstation (1.18 ns per character).

cs.DS

Suffixient Sets

We define a suffixient set for a text $T [1..n]$ to be a set $S$ of positions between 1 and $n$ such that, for any edge descending from a node $u$ to a node $v$ in the suffix tree of $T$, there is an element $s \in S$ such that $u$'s path label is a suffix of $T [1..s - 1]$ and $T [s]$ is the first character of $(u, v)$'s edge label. We first show there is a suffixient set of cardinality at most $2 \bar{r}$, where $\bar{r}$ is the number of runs in the Burrows-Wheeler Transform of the reverse of $T$. We then show that, given a straight-line program for $T$ with $g$ rules, we can build an $O (\bar{r} + g)$-space index with which, given a pattern $P [1..m]$, we can find the maximal exact matches (MEMs) of $P$ with respect to $T$ in $O (m \log (σ) / \log n + d \log n)$ time, where $σ$ is the size of the alphabet and $d$ is the number of times we would fully or partially descend edges in the suffix tree of $T$ while finding those MEMs.

cs.DS

Faster Maximal Exact Matches with Lazy LCP Evaluation

MONI (Rossi et al., {\it JCB} 2022) is a BWT-based compressed index for computing the matching statistics and maximal exact matches (MEMs) of a pattern (usually a DNA read) with respect to a highly repetitive text (usually a database of genomes) using two operations: LF-steps and longest common extension (LCE) queries on a grammar-compressed representation of the text. In practice, most of the operations are constant-time LF-steps but most of the time is spent evaluating LCE queries. In this paper we show how (a variant of) the latter can be evaluated lazily, so as to bound the total time MONI needs to process the pattern in terms of the number of MEMs between the pattern and the text, while maintaining logarithmic latency.

cs.DS