Louise Zhuang | Searcharxiv

arXiv2026

A Wavefield Correlation Approach to Improve Sound Speed Estimation in Ultrasound Autofocusing

In pulse-echo ultrasound, aberration often degrades image quality when beamforming does not account for wavefront distortions. To address this issue, local sound speed estimators have been developed in the past decade for distributed aberration correction. Recently, methods based on iterative optimization have improved sound speed accuracy with respect to earlier approaches. However, the accuracy of these newer methods is limited by media with reverberation clutter and by the straight-ray model of wave propagation. To address these challenges, we propose using wavefield correlation (WFC) beamforming when performing sound speed optimization. WFC, an ultrasound adaptation of reverse time migration, correlates simulated forward-propagated transmit wavefields and backwards-propagated receive wavefields in order to reconstruct images. This process more accurately models wave propagation in heterogeneous media and can decrease diffuse clutter due to its spatiotemporal matched filtering effect. We implement herein a WFC beamformer using an auto-differentiation software and estimate the sound speed map by optimizing a regularized common-midpoint phase focusing criterion using gradient descent. This approach is compared to a previous method relying on delay and sum (DAS) with straight-ray time delay calculations on a variety of simulated, phantom, and in vivo data with large sound speed variations and clutter. Results show that using WFC decreases sound speed estimation error, leading to improvements in resolution and contrast in the corrected image. In particular, these promising results have potential to improve pulse-echo imaging for challenging clinical scenarios.

physics.med-ph↗

arXiv2025

Ultrasound Autofocusing: Common Midpoint Phase Error Optimization via Differentiable Beamforming

In ultrasound imaging, propagation of an acoustic wavefront through heterogeneous media causes phase aberrations that degrade the coherence of the reflected wavefront, leading to reduced image resolution and contrast. Adaptive imaging techniques attempt to correct this phase aberration and restore coherence, leading to improved focusing of the image. We propose an autofocusing paradigm for aberration correction in ultrasound imaging by fitting an acoustic velocity field to pressure measurements, via optimization of the common midpoint phase error (CMPE), using a straight-ray wave propagation model for beamforming in diffusely scattering media. We show that CMPE induced by heterogeneous acoustic velocity is a robust measure of phase aberration that can be used for acoustic autofocusing. CMPE is optimized iteratively using a differentiable beamforming approach to simultaneously improve the image focus while estimating the acoustic velocity field of the interrogated medium. The approach relies solely on wavefield measurements using a straight-ray integral solution of the two-way time-of-flight without explicit numerical time-stepping models of wave propagation. We demonstrate method performance through in silico simulations, in vitro phantom measurements, and in vivo mammalian models, showing practical applications in distributed aberration quantification, correction, and velocity estimation for medical ultrasound autofocusing.

physics.med-ph↗