arXiv subjects

Luigi G. Occhipinti

Publications and source records attributed to Luigi G. Occhipinti.

16 recordsLinked to original sources

arXiv2026

Design and Biomechanical Evaluation of a Lightweight Low-Complexity Soft Bilateral Ankle Exoskeleton

Many people could benefit from exoskeleton assistance during gait, for either medical or nonmedical purposes. But exoskeletons bring added mass and structure, which in turn require compensating for. In this work, we present a lightweight, low-complexity, soft bilateral ankle exoskeleton for plantarflexion assistance, with a shoe attachment design that can be mounted on top of any pair of shoes. Experimental tests show no significant difference in lower limb kinematics and kinetics when wearing the exoskeleton in zero-torque mode relative to not wearing an exoskeleton, showing that our device does not obstruct healthy gait, and proving it as a compliant and comfortable device, promising to provide effective assistance. Hence, a control system was developed, and additional tests are underway.

cs.RO↗

arXiv2026

Real-Time Prediction of Lower Limb Joint Kinematics, Kinetics, and Ground Reaction Force using Wearable Sensors and Machine Learning

Walking is a key movement of interest in biomechanics, yet gold-standard data collection methods are time- and cost-expensive. This paper presents a real-time, multimodal, high sample rate lower-limb motion capture framework, based on wireless wearable sensors and machine learning algorithms. Random Forests are used to estimate joint angles from IMU data, and ground reaction force (GRF) is predicted from instrumented insoles, while joint moments are predicted from angles and GRF using deep learning based on the ResNet-16 architecture. All three models achieve good accuracy compared to literature, and the predictions are logged at 1 kHz with a minimal delay of 23 ms for 20s worth of input data. The present work fully relies on wearable sensors, covers all five major lower limb joints, and provides multimodal comprehensive estimations of GRF, joint angles, and moments with minimal delay suitable for biofeedback applications.

eess.SY↗

arXiv2025

Biomimetic Metamaterial-based Interface for Decoding Heterogeneous Mechanodermal Activity

Human skin acts as a dynamic biomechanical interface that conveys critical physiological and behavioural information through spatiotemporally distributed deformations. Due to the limited capabilities of current sensing technologies, the spatiotemporal diversity of its mechanical cues has remained underutilised to date, preventing these mechanisms from being used to capture and decode the full spectrum of underlying physiological states. In this work, we define this heterogeneous set of mechanical signals as mechanodermal activity (MDA) and introduce the biomimetic metamaterial-based interface (BMMI), an engineered auxetic metamaterial substrate that reproduces the microrelief and mechanoreceptor architecture of natural skin. The BMMI allows selective capture of diverse MDA signals from adjacent skin regions with simultaneous signal amplification and noise suppression, and permits straightforward modulation to accommodate various scenarios. Combined with bespoke algorithms, the wireless BMMI device decodes MDA accurately and robustly for multimodal communication interfaces, unleashing applications in healthcare monitoring and human-machine interaction.

q-bio.NC↗

arXiv2025

Physiology-informed layered sensing for intelligent human-exoskeleton interaction

Wearable exoskeletons hold transformative promise for restoring mobility across diverse users with muscular weakness or other impairments. However, their translation beyond laboratory environments remains limited by sensing systems that capture movement but not underlying physiology. Here, we present a soft, lightweight smart leg sleeve that achieves anatomically aligned, layered multimodal sensing by integrating textile-based surface electromyography (sEMG) electrodes, ultrasensitive textile strain sensors, and inertial measurement units (IMUs). Each sensing modality targets a distinct physiological layer: IMUs track joint kinematics at the skeletal level, sEMG monitors muscle activation at the muscular level, and strain sensors detect skin deformation at the cutaneous level. Together, these sensors provide real-time perception to support three core objectives: controlling personalized assistance, optimizing user effort, and safeguarding against injury risks. The system is skin-conformal, mechanically compliant, and seamlessly integrated with a custom exoskeleton ($<20$~g total sensor and electronics weight). We demonstrate: (1) accurate ankle joint moment estimation (RMSE = 0.13~Nm/kg), (2) real-time classification of metabolic trends (accuracy = 97.1\%), and (3) injury risk detection within 100~ms (recall = 0.96), all validated on unseen users using a leave-one-subject-out protocol. This work establishes a physiology-aligned sensing architecture that reframes exoskeleton perception from motion tracking to real-time physiological decoding, offering a pathway towards intelligent, adaptive, and personalized wearable robotics.

eess.SY↗

arXiv2025

An AI-Driven Multimodal Smart Home Platform for Continuous Monitoring and Assistance in Post-Stroke Motor Impairment

At-home rehabilitation for post-stroke patients presents significant challenges, as continuous, personalized care is often limited outside clinical settings. Moreover, the lack of integrated solutions capable of simultaneously monitoring motor recovery and providing intelligent assistance in home environments hampers rehabilitation outcomes. Here, we present a multimodal smart home platform designed for continuous, at-home rehabilitation of post-stroke patients, integrating wearable sensing, ambient monitoring, and adaptive automation. A plantar pressure insole equipped with a machine learning pipeline classifies users into motor recovery stages with up to 94\% accuracy, enabling quantitative tracking of walking patterns during daily activities. An optional head-mounted eye-tracking module, together with ambient sensors such as cameras and microphones, supports seamless hands-free control of household devices with a 100\% success rate and sub-second response time. These data streams are fused locally via a hierarchical Internet of Things (IoT) architecture, ensuring low latency and data privacy. An embedded large language model (LLM) agent, Auto-Care, continuously interprets multimodal data to provide real-time interventions -- issuing personalized reminders, adjusting environmental conditions, and notifying caregivers. Implemented in a post-stroke context, this integrated smart home platform increased mean user satisfaction from 3.9 $\pm$ 0.8 in conventional home environments to 8.4 $\pm$ 0.6 with the full system ($n=20$). Beyond stroke, the system offers a scalable, patient-centered framework with potential for long-term use in broader neurorehabilitation and aging-in-place applications.

cs.HC↗

arXiv2025

Monitoring Nitric Oxide in Trigeminal Neuralgia Rats with a Cerium Single-Atom Nanozyme Electrochemical Biosensor

Trigeminal neuralgia (TN) is the most common neuropathic disorder; however, its pathogenesis remains unclear. A prevailing theory suggests that nitric oxide (NO) may induce nerve compression and irritation via vascular dilation, thereby being responsible for the condition, making real-time detection of generated NO critical. However, traditional evaluations of NO rely on indirect colorimetric or chemiluminescence techniques, which offer limited sensitivity and spatial resolution for its real-time assessment in biological environments. Herein, we reported the development of a highly sensitive NO electrochemical biosensor based cerium single-atom nanozyme (Ce1-CN) with ultrawide linear range from 1.08 nM to 143.9 μM, and ultralow detection limit of 0.36 nM, which enables efficient and real-time evaluation of NO in TN rats. In-situ attenuated total reflection surface-enhanced infrared spectroscopy combined with density functional theory calculations revealed the high-performance biosensing mechanism, whereby the Ce centers in Ce1-CN nanoenzymes adsorb NO and subsequently react with OH- to form *HNO2. Results demonstrated that NO concentration was associated with TN onset. Following carbamazepine treatment, NO production from nerves decreased, accompanied by an alleviation of pain. These findings indicate that the biosensor serves as a valuable tool for investigating the pathogenesis of TN and guiding subsequent therapeutic strategies.

q-bio.BM↗

arXiv2025

AI-Driven Smart Sportswear for Real-Time Fitness Monitoring Using Textile Strain Sensors

Wearable biosensors have revolutionized human performance monitoring by enabling real-time assessment of physiological and biomechanical parameters. However, existing solutions lack the ability to simultaneously capture breath-force coordination and muscle activation symmetry in a seamless and non-invasive manner, limiting their applicability in strength training and rehabilitation. This work presents a wearable smart sportswear system that integrates screen-printed graphene-based strain sensors with compact electronics for wireless data transfer and a deep learning framework for real-time classification of exercise execution quality. By leveraging 1D ResNet-18 for feature extraction, the system achieves 92.1% classification accuracy across six exercise conditions, distinguishing between breathing irregularities and asymmetric muscle exertion. Additionally, t-SNE analysis and Grad-CAM-based explainability visualization confirm that the network accurately captures biomechanically relevant features, ensuring robust interpretability. The proposed system establishes a foundation for next-generation AI-powered sportswear, with applications in fitness optimization, injury prevention, and adaptive rehabilitation training.

eess.SP↗

arXiv2025

Wireless Silent Speech Interface Using Multi-Channel Textile EMG Sensors Integrated into Headphones

This paper presents a novel wireless silent speech interface (SSI) integrating multi-channel textile-based EMG electrodes into headphone earmuff for real-time, hands-free communication. Unlike conventional patch-based EMG systems, which require large-area electrodes on the face or neck, our approach ensures comfort, discretion, and wearability while maintaining robust silent speech decoding. The system utilizes four graphene/PEDOT:PSS-coated textile electrodes to capture speech-related neuromuscular activity, with signals processed via a compact ESP32-S3-based wireless readout module. To address the challenge of variable skin-electrode coupling, we propose a 1D SE-ResNet architecture incorporating squeeze-and-excitation (SE) blocks to dynamically adjust per-channel attention weights, enhancing robustness against motion-induced impedance variations. The proposed system achieves 96% accuracy on 10 commonly used voice-free control words, outperforming conventional single-channel and non-adaptive baselines. Experimental validation, including XAI-based attention analysis and t-SNE feature visualization, confirms the adaptive channel selection capability and effective feature extraction of the model. This work advances wearable EMG-based SSIs, demonstrating a scalable, low-power, and user-friendly platform for silent communication, assistive technologies, and human-computer interaction.

cs.HC↗

arXiv2025

Wearable intelligent throat enables natural speech in stroke patients with dysarthria

Wearable silent speech systems hold significant potential for restoring communication in patients with speech impairments. However, seamless, coherent speech remains elusive, and clinical efficacy is still unproven. Here, we present an AI-driven intelligent throat (IT) system that integrates throat muscle vibrations and carotid pulse signal sensors with large language model (LLM) processing to enable fluent, emotionally expressive communication. The system utilizes ultrasensitive textile strain sensors to capture high-quality signals from the neck area and supports token-level processing for real-time, continuous speech decoding, enabling seamless, delay-free communication. In tests with five stroke patients with dysarthria, IT's LLM agents intelligently corrected token errors and enriched sentence-level emotional and logical coherence, achieving low error rates (4.2% word error rate, 2.9% sentence error rate) and a 55% increase in user satisfaction. This work establishes a portable, intuitive communication platform for patients with dysarthria with the potential to be applied broadly across different neurological conditions and in multi-language support systems.

eess.AS↗

arXiv2024

Deep Learning for Motion Classification in Ankle Exoskeletons Using Surface EMG and IMU Signals

Ankle exoskeletons have garnered considerable interest for their potential to enhance mobility and reduce fall risks, particularly among the aging population. The efficacy of these devices relies on accurate real-time prediction of the user's intended movements through sensor-based inputs. This paper presents a novel motion prediction framework that integrates three Inertial Measurement Units (IMUs) and eight surface Electromyography (sEMG) sensors to capture both kinematic and muscular activity data. A comprehensive set of activities, representative of everyday movements in barrier-free environments, was recorded for the purpose. Our findings reveal that Convolutional Neural Networks (CNNs) slightly outperform Long Short-Term Memory (LSTM) networks on a dataset of five motion tasks, achieving classification accuracies of $96.5 \pm 0.8 \%$ and $87.5 \pm 2.9 \%$, respectively. Furthermore, we demonstrate the system's proficiency in transfer learning, enabling accurate motion classification for new subjects using just ten samples per class for finetuning. The robustness of the model is demonstrated by its resilience to sensor failures resulting in absent signals, maintaining reliable performance in real-world scenarios. These results underscore the potential of deep learning algorithms to enhance the functionality and safety of ankle exoskeletons, ultimately improving their usability in daily life.

eess.SY↗

arXiv2024

A deep learning-enabled smart garment for accurate and versatile sleep conditions monitoring in daily life

In wearable smart systems, continuous monitoring and accurate classification of different sleep-related conditions are critical for enhancing sleep quality and preventing sleep-related chronic conditions. However, the requirements for device-skin coupling quality in electrophysiological sleep monitoring systems hinder the comfort and reliability of night wearing. Here, we report a washable, skin-compatible smart garment sleep monitoring system that captures local skin strain signals under weak device-skin coupling conditions without positioning or skin preparation requirements. A printed textile-based strain sensor array responds to strain from 0.1% to 10% with a gauge factor as high as 100 and shows independence to extrinsic motion artefacts via strain-isolating printed pattern design. Through reversible starching treatment, ink penetration depth during direct printing on garments is controlled to achieve batch-to-batch performance variation < 10%. Coupled with deep learning, explainable artificial intelligence (XAI), and transfer learning data processing, the smart garment is capable of classifying six sleep states with an accuracy of 98.6%, maintaining excellent explainability (classification with low bias) and generalization (95% accuracy on new users with few-shot learning less than 15 samples per class) in practical applications, paving the way for next-generation daily sleep healthcare management.

eess.SP↗

arXiv2024

SSVT: Self-Supervised Vision Transformer For Eye Disease Diagnosis Based On Fundus Images

Machine learning-based fundus image diagnosis technologies trigger worldwide interest owing to their benefits such as reducing medical resource power and providing objective evaluation results. However, current methods are commonly based on supervised methods, bringing in a heavy workload to biomedical staff and hence suffering in expanding effective databases. To address this issue, in this article, we established a label-free method, name 'SSVT',which can automatically analyze un-labeled fundus images and generate high evaluation accuracy of 97.0% of four main eye diseases based on six public datasets and two datasets collected by Beijing Tongren Hospital. The promising results showcased the effectiveness of the proposed unsupervised learning method, and the strong application potential in biomedical resource shortage regions to improve global eye health.

eess.IV↗

arXiv2024

Universal Murray's law for optimised fluid transport in synthetic structures

Materials following Murray's law are of significant interest due to their unique porous structure and optimal mass transfer ability. However, it is challenging to construct such biomimetic hierarchical channels with perfectly cylindrical pores in synthetic systems following the existing theory. Achieving superior mass transport capacity revealed by Murray's law in nanostructured materials has thus far remained out of reach. We propose a Universal Murray's law applicable to a wide range of hierarchical structures, shapes and generalised transfer processes. We experimentally demonstrate optimal flow of various fluids in hierarchically planar and tubular graphene aerogel structures to validate the proposed law. By adjusting the macroscopic pores in such aerogel-based gas sensors, we also show a significantly improved sensor response dynamic. Our work provides a solid framework for designing synthetic Murray materials with arbitrarily shaped channels for superior mass transfer capabilities, with future implications in catalysis, sensing and energy applications.

physics.app-ph↗

arXiv2024

Real-time, noise and drift resilient formaldehyde sensing at room temperature with aerogel filaments

Formaldehyde, a known human carcinogen, is a common indoor air pollutant. However, its real-time and selective recognition from interfering gases remains challenging, especially for low-power sensors suffering from noise and baseline drift. We report a fully 3D-printed quantum dot/graphene-based aerogel sensor for highly sensitive and real-time recognition of formaldehyde at room temperature. By optimising the morphology and doping of the printed structures, we achieve a record-high response of 15.23 percent for 1 parts-per-million formaldehyde and an ultralow detection limit of 8.02 parts-per-billion consuming only 130 uW power. Based on measured dynamic response snapshots, we also develop an intelligent computational algorithm for robust and accurate detection in real time despite simulated substantial noise and baseline drift, hitherto unachievable for room-temperature sensors. Our framework in combining materials engineering, structural design and computational algorithm to capture dynamic response offers unprecedented real-time identification capabilities of formaldehyde and other volatile organic compounds at room temperature.

physics.app-ph↗

arXiv2023

Ultrasensitive Textile Strain Sensors Redefine Wearable Silent Speech Interfaces with High Machine Learning Efficiency

Our research presents a wearable Silent Speech Interface (SSI) technology that excels in device comfort, time-energy efficiency, and speech decoding accuracy for real-world use. We developed a biocompatible, durable textile choker with an embedded graphene-based strain sensor, capable of accurately detecting subtle throat movements. This sensor, surpassing other strain sensors in sensitivity by 420%, simplifies signal processing compared to traditional voice recognition methods. Our system uses a computationally efficient neural network, specifically a one-dimensional convolutional neural network with residual structures, to decode speech signals. This network is energy and time-efficient, reducing computational load by 90% while achieving 95.25% accuracy for a 20-word lexicon and swiftly adapting to new users and words with minimal samples. This innovation demonstrates a practical, sensitive, and precise wearable SSI suitable for daily communication applications.

eess.AS↗

arXiv2023

Human Body Digital Twin: A Master Plan

A human body digital twin (DT) is a virtual representation of an individual's physiological state, created using real-time data from sensors and medical test devices, with the purpose of simulating, predicting, and optimizing health outcomes through advanced analytics and simulations. The human body DT has the potential to revolutionize healthcare and wellness, but its responsible and effective implementation requires consideration of various factors. This article presents a comprehensive overview of the current status and future prospects of the human body DT and proposes a five-level roadmap for its development. The roadmap covers the development of various components, such as wearable devices, data collection, data analysis, and decision-making systems. The article also highlights the necessary support, security, cost, and ethical considerations that must be addressed in order to ensure responsible and effective implementation of the human body DT. The proposed roadmap provides a framework for guiding future development and offers a unique perspective on the future of the human body DT, facilitating new interdisciplinary research and innovative solutions in this rapidly evolving field.

cs.AI↗