arXiv subjects

Lukas Buess

Publications and source records attributed to Lukas Buess.

4 recordsLinked to original sources

arXiv2026

Perceptual implications of automatic anonymization in pathological speech

Automatic anonymization is increasingly used to enable ethical sharing of clinical speech, yet its perceptual and clinical consequences remain undercharacterized. We present a human-centered evaluation of automatically anonymized pathological speech, using a structured protocol with ten native and non-native German listeners spanning clinical and signal-processing expertise. The cohort comprised 180 German speakers from CLP, Dysarthria, Dysglossia, Dysphonia, and adult and child controls. Each original recording and its automatically-anonymized counterpart was evaluated on four tasks: zero-shot Turing-style discrimination, few-shot discrimination after brief familiarization, 5-point quality rating, and 4-point blinded clinical severity rating by a senior phoniatrician. Listeners detected anonymization at 91% zero-shot and 93% few-shot accuracy, with significant variation across disorders (p=0.008) that attenuated with familiarization. Perceived quality dropped by 30 ppts on a 0-100 scale (p<0.001), reorganizing the perceived-quality hierarchy across groups. Native language modulated detectability but not quality degradation, while domain expertise modulated quality degradation but not detectability, a double dissociation between the two listener attributes; speaker sex and age produced no detectable bias. Clinical severity ratings were preserved at near-perfect agreement in Dysarthria, Dysglossia, and Dysphonia (quadratic-weighted Cohen's kappa 0.87-0.94), with no recording shifting by more than one grade. Crucially, perceptual outcomes were decoupled from the standard computational privacy metric: the pathology with the strongest computational anonymization was the least perceptually conspicuous, and vice versa. These findings argue for disorder-stratified, listener-stratified, clinician-validated evaluation as the minimum standard for licensing anonymized speech for clinical use.

eess.AS↗

arXiv2025

SpeechCT-CLIP: Distilling Text-Image Knowledge to Speech for Voice-Native Multimodal CT Analysis

Spoken communication plays a central role in clinical workflows. In radiology, for example, most reports are created through dictation. Yet, nearly all medical AI systems rely exclusively on written text. In this work, we address this gap by exploring the feasibility of learning visual-language representations directly from spoken radiology reports. Specifically, we synthesize a large-scale dataset (Speech-RATE) of spoken radiology reports and train SpeechCT-CLIP, a contrastive model that aligns speech and 3D CT volumes in a shared representation space. While naive speech-based models underperform compared to text-trained counterparts, we show that knowledge distillation from a pretrained text-image CLIP model effectively transfers semantic alignment capabilities from text to speech, substantially narrowing this gap. Experiments demonstrate improved zero-shot classification F1 from 0.623 to 0.705, recovering 88% of the performance difference, and strong retrieval results without requiring text at inference. These findings highlight speech as a practical alternative to text in multimodal pretraining and open the door to voice-driven diagnostic support tools in clinical practice.

eess.AS↗

arXiv2025

CXR-CML: Improved zero-shot classification of long-tailed multi-label diseases in Chest X-Rays

Chest radiography (CXR) plays a crucial role in the diagnosis of various diseases. However, the inherent class imbalance in the distribution of clinical findings presents a significant challenge for current self-supervised deep learning models. These models often fail to accurately classify long-tailed classes. Current Vision-Language models such as Contrastive Language Image Pre-training (CLIP) models effectively model the manifold distribution of the latent space, enabling high zero-shot classification accuracies. Although CLIP performs well on most of the primary classes in the dataset, our work reveals that its effectiveness decreases significantly for classes with a long-tailed distribution. Our approach employs a class-weighting mechanism that directly aligns with the distribution of classes within the latent space. This method ensures a substantial improvement in overall classification performance, with particular emphasis on enhancing the recognition and accuracy of rarely observed classes. We accomplish this by applying Gaussian Mixture Model (GMM) clustering to the latent space. The subsequent clusters are further refined by Student t-distribution, followed by a metric loss that utilizes the altered embeddings. Our approach facilitates stable and adaptive clustering of the features. This results in a notable average improvement of 7\% points in zero-shot AUC scores across 40 classes in the MIMIC-CXR-JPG dataset from previous SOTA models.

cs.CV↗

arXiv2025

From large language models to multimodal AI: A scoping review on the potential of generative AI in medicine

Generative artificial intelligence (AI) models, such as diffusion models and OpenAI's ChatGPT, are transforming medicine by enhancing diagnostic accuracy and automating clinical workflows. The field has advanced rapidly, evolving from text-only large language models for tasks such as clinical documentation and decision support to multimodal AI systems capable of integrating diverse data modalities, including imaging, text, and structured data, within a single model. The diverse landscape of these technologies, along with rising interest, highlights the need for a comprehensive review of their applications and potential. This scoping review explores the evolution of multimodal AI, highlighting its methods, applications, datasets, and evaluation in clinical settings. Adhering to PRISMA-ScR guidelines, we systematically queried PubMed, IEEE Xplore, and Web of Science, prioritizing recent studies published up to the end of 2024. After rigorous screening, 144 papers were included, revealing key trends and challenges in this dynamic field. Our findings underscore a shift from unimodal to multimodal approaches, driving innovations in diagnostic support, medical report generation, drug discovery, and conversational AI. However, critical challenges remain, including the integration of heterogeneous data types, improving model interpretability, addressing ethical concerns, and validating AI systems in real-world clinical settings. This review summarizes the current state of the art, identifies critical gaps, and provides insights to guide the development of scalable, trustworthy, and clinically impactful multimodal AI solutions in healthcare.

cs.AI↗