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Lulu Kang

Publications and source records attributed to Lulu Kang.

29 records · Page 2Linked to original sources

Sampling Constrained Continuous Probability Distributions: A Review

The problem of sampling constrained continuous distributions has frequently appeared in many machine/statistical learning models. Many Monte Carlo Markov Chain (MCMC) sampling methods have been adapted to handle different types of constraints on the random variables. Among these methods, Hamilton Monte Carlo (HMC) and the related approaches have shown significant advantages in terms of computational efficiency compared to other counterparts. In this article, we first review HMC and some extended sampling methods, and then we concretely explain three constrained HMC-based sampling methods, reflection, reformulation, and spherical HMC. For illustration, we apply these methods to solve three well-known constrained sampling problems, truncated multivariate normal distributions, Bayesian regularized regression, and nonparametric density estimation. In this review, we also connect constrained sampling with another similar problem in the statistical design of experiments of constrained design space.

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Locally Optimal Design for A/B Testing in the Presence of Covariates and Network Connection

A/B test, a simple type of controlled experiment, refers to the statistical procedure of experimenting to compare two treatments applied to test subjects. For example, many IT companies frequently conduct A/B tests on their users who are connected and form social networks. Often, the users' responses could be related to the network connection. In this paper, we assume that the users, or the test subjects of the experiments, are connected on an undirected network, and the responses of two connected users are correlated. We include the treatment assignment, covariate features, and network connection in a conditional autoregressive model. Based on this model, we propose a design criterion that measures the variance of the estimated treatment effect and allocate the treatment settings to the test subjects by minimizing the criterion. Since the design criterion depends on an unknown network correlation parameter, we adopt the locally optimal design method and develop a hybrid optimization approach to obtain the optimal design. Through synthetic and real social network examples, we demonstrate the value of including network dependence in designing A/B experiments and validate that the proposed locally optimal design is robust to the choices of parameters.

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Fair and Diverse Allocation of Scarce Resources

We aim to design a fairness-aware allocation approach to maximize the geographical diversity and avoid unfairness in the sense of demographic disparity. During the development of this work, the COVID-19 pandemic is still spreading in the U.S. and other parts of the world on large scale. Many poor communities and minority groups are much more vulnerable than the rest. To provide sufficient vaccine and medical resources to all residents and effectively stop the further spreading of the pandemic, the average medical resources per capita of a community should be independent of the community's demographic features but only conditional on the exposure rate to the disease. In this article, we integrate different aspects of resource allocation and seek a synergistic intervention strategy that gives vulnerable populations with higher priority when distributing medical resources. This prevention-centered strategy is a trade-off between geographical coverage and social group fairness. The proposed principle can be applied to other scarce resources and social benefits allocation.

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Particle-based Energetic Variational Inference

We introduce a new variational inference (VI) framework, called energetic variational inference (EVI). It minimizes the VI objective function based on a prescribed energy-dissipation law. Using the EVI framework, we can derive many existing Particle-based Variational Inference (ParVI) methods, including the popular Stein Variational Gradient Descent (SVGD) approach. More importantly, many new ParVI schemes can be created under this framework. For illustration, we propose a new particle-based EVI scheme, which performs the particle-based approximation of the density first and then uses the approximated density in the variational procedure, or "Approximation-then-Variation" for short. Thanks to this order of approximation and variation, the new scheme can maintain the variational structure at the particle level, and can significantly decrease the KL-divergence in each iteration. Numerical experiments show the proposed method outperforms some existing ParVI methods in terms of fidelity to the target distribution.

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A Generative Approach to Joint Modeling of Quantitative and Qualitative Responses

In many scientific areas, data with quantitative and qualitative (QQ) responses are commonly encountered with a large number of predictors. By exploring the association between QQ responses, existing approaches often consider a joint model of QQ responses given the predictor variables. However, the dependency among predictive variables also provides useful information for modeling QQ responses. In this work, we propose a generative approach to model the joint distribution of the QQ responses and predictors. The proposed generative model provides efficient parameter estimation under a penalized likelihood framework. It achieves accurate classification for qualitative response and accurate prediction for quantitative response with efficient computation. Because of the generative approach framework, the asymptotic optimality of classification and prediction of the proposed method can be established under some regularity conditions. The performance of the proposed method is examined through simulations and real case studies in material science and genetics.

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Covariate Balancing Based on Kernel Density Estimates for Controlled Experiments

Controlled experiments are widely used in many applications to investigate the causal relationship between input factors and experimental outcomes. A completely randomized design is usually used to randomly assign treatment levels to experimental units. When covariates of the experimental units are available, the experimental design should achieve covariate balancing among the treatment groups, such that the statistical inference of the treatment effects is not confounded with any possible effects of covariates. However, covariate imbalance often exists, because the experiment is carried out based on a single realization of the complete randomization. It is more likely to occur and worsen when the size of the experimental units is small or moderate. In this paper, we introduce a new covariate balancing criterion, which measures the differences between kernel density estimates of the covariates of treatment groups. To achieve covariate balance before the treatments are randomly assigned, we partition the experimental units by minimizing the criterion, then randomly assign the treatment levels to the partitioned groups. Through numerical examples, we show that the proposed partition approach can improve the accuracy of the difference-in-mean estimator and outperforms the complete randomization and rerandomization approaches.

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Bayesian Auxiliary Variable Model for Birth Records Data with Qualitative and Quantitative Responses

Many applications involve data with qualitative and quantitative responses. When there is an association between the two responses, a joint model will provide improved results than modeling them separately. In this paper, we propose a Bayesian method to jointly model such data. The joint model links the qualitative and quantitative responses and can assess their dependency strength via a latent variable. The posterior distributions of parameters are obtained through an efficient MCMC sampling algorithm. The simulation shows that the proposed method can improve the prediction capacity for both responses. We apply the proposed joint model to the birth records data acquired by the Virginia Department of Health and study the mutual dependence between preterm birth of infants and their birth weights.

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A Maximin $Φ_{p}$-Efficient Design for Multivariate GLM

Experimental designs for a generalized linear model (GLM) often depend on the specification of the model, including the link function, the predictors, and unknown parameters, such as the regression coefficients. To deal with uncertainties of these model specifications, it is important to construct optimal designs with high efficiency under such uncertainties. Existing methods such as Bayesian experimental designs often use prior distributions of model specifications to incorporate model uncertainties into the design criterion. Alternatively, one can obtain the design by optimizing the worst-case design efficiency with respect to uncertainties of model specifications. In this work, we propose a new Maximin $Φ_p$-Efficient (or Mm-$Φ_p$ for short) design which aims at maximizing the minimum $Φ_p$-efficiency under model uncertainties. Based on the theoretical properties of the proposed criterion, we develop an efficient algorithm with sound convergence properties to construct the Mm-$Φ_p$ design. The performance of the proposed Mm-$Φ_p$ design is assessed through several numerical examples.

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Gaussian Process Assisted Active Learning of Physical Laws

In many areas of science and engineering, discovering the governing differential equations from the noisy experimental data is an essential challenge. It is also a critical step in understanding the physical phenomena and prediction of the future behaviors of the systems. However, in many cases, it is expensive or time-consuming to collect experimental data. This article provides an active learning approach to estimate the unknown differential equations accurately with reduced experimental data size. We propose an adaptive design criterion combining the D-optimality and the maximin space-filling criterion. In contrast to active learning for other regression models, the D-optimality here requires the unknown solution of the differential equations and derivatives of the solution. We estimate the Gaussian process (GP) regression models from the available experimental data and use them as the surrogates of these unknown solution functions. The derivatives of the estimated GP models are derived and used to substitute the derivatives of the solution. Variable selection-based regression methods are used to learn the differential equations from the experimental data. Through multiple case studies, we demonstrate the proposed approach outperforms the D-optimality and the maximin space-filling design alone in terms of model accuracy and data economy.

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Is a Transformed Low Discrepancy Design Also Low Discrepancy?

Experimental designs intended to match arbitrary target distributions are typically constructed via a variable transformation of a uniform experimental design. The inverse distribution function is one such transformation. The discrepancy is a measure of how well the empirical distribution of any design matches its target distribution. This chapter addresses the question of whether a variable transformation of a low discrepancy uniform design yields a low discrepancy design for the desired target distribution. The answer depends on the two kernel functions used to define the respective discrepancies. If these kernels satisfy certain conditions, then the answer is yes. However, these conditions may be undesirable for practical reasons. In such a case, the transformation of a low discrepancy uniform design may yield a design with a large discrepancy. We illustrate how this may occur. We also suggest some remedies. One remedy is to ensure that the original uniform design has optimal one-dimensional projection, but this remedy works best if the design is dense, or in other words, the ratio of sample size divided by the dimension of the random variable is relatively large. Another remedy is to use the transformed design as the input to a coordinate-exchange algorithm that optimizes the desired discrepancy, and this works for both dense or sparse designs. The effectiveness of these two remedies is illustrated via simulation.

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D-optimal Design for Network A/B Testing

A/B testing refers to the statistical procedure of conducting an experiment to compare two treatments, A and B, applied to different testing subjects. It is widely used by technology companies such as Facebook, LinkedIn, and Netflix, to compare different algorithms, web-designs, and other online products and services. The subjects participating these online A/B testing experiments are users who are connected in different scales of social networks. Two connected subjects are similar in terms of their social behaviors, education and financial background, and other demographic aspects. Hence, it is only natural to assume that their reactions to the online products and services are related to their network adjacency. In this paper, we propose to use the conditional auto-regressive model to present the network structure and include the network effects in the estimation and inference of the treatment effect. A D-optimal design criterion is developed based on the proposed model. Mixed integer programming formulations are developed to obtain the D-optimal designs. The effectiveness of the proposed method is shown through numerical results with synthetic networks and real social networks.

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