SearcharxivSearch

arXiv subjects

Luohong Wu

Publications and source records attributed to Luohong Wu.

5 recordsLinked to original sources

NeuralBoneReg: An Instance-Specific Label-Free Point Cloud-Based Method for Multi-Modal Bone Surface Registration

In computer- and robot-assisted orthopedic surgery (CAOS), patient-specific surgical plans derived from preoperative imaging define target locations and implant trajectories. During surgery, these plans must be accurately transferred, relying on precise cross-registration between preoperative and intraoperative data. However, substantial modality heterogeneity across imaging modalities makes this registration challenging and error-prone. Robust, automatic, and modality-agnostic bone surface registration is therefore clinically important. We propose NeuralBoneReg, a self-supervised, surface-based framework that registers bone surfaces using 3D point clouds as a modality-agnostic representation. NeuralBoneReg includes two modules: an implicit neural unsigned distance field (UDF) that learns the preoperative bone model, and an MLP-based registration module that performs global initialization and local refinement by generating transformation hypotheses to align the intraoperative point cloud with the neural UDF. Unlike SOTA supervised methods, NeuralBoneReg operates in a self-supervised manner, without requiring inter-subject training data. We evaluated NeuralBoneReg against baseline methods on two publicly available multi-modal datasets: a CT-ultrasound dataset of the fibula and tibia (UltraBones100k) and a CT-RGB-D dataset of spinal vertebrae (SpineDepth). The evaluation also includes a newly introduced CT-ultrasound dataset of cadaveric subjects containing femur and pelvis (UltraBones-Hip), which will be made publicly available. NeuralBoneReg matches or surpasses existing methods across all datasets, achieving mean RRE/RTE of 1.83°/2.02 mm on UltraBones100k, 1.90°/1.56 mm on UltraBones-Hip, and 3.78°/2.80 mm on SpineDepth. These results demonstrate strong generalizability across anatomies and modalities, providing robust and accurate cross-modal alignment for CAOS.

cs.CV

Logit Distillation on Manifolds: Mapping by Learning

A simple way to improve the performance of almost any machine learning model is not to train a single but several models with diverse algorithms which will make slightly distinct kinds of predictions and errors on the same data, and thus improve the average predictions and robustness. However, making predictions using a whole ensemble of models is cumbersome and computationally too expensive to allow deployment to a large number of users, especially if the models are large neural nets. In response to this, we introduce a layer and point wise projection mapping, which maps student and teacher representations into an aligned high-dimensional embedding space during training process. The proposed approach combined with LoRA injection reduces the student model trainable parameters to less than 1% of the teacher model, while significantly improving word error rate (WER) compared to other distillation methods, as demonstrated in ablation studies. Unlike a mixture of experts, our method can be trained rapidly and in parallel.

cs.LG

UltraBoneUDF: Self-supervised Bone Surface Reconstruction from Ultrasound Based on Neural Unsigned Distance Functions

Bone surface reconstruction is an essential component of computer-assisted orthopedic surgery(CAOS), forming the foundation for both preoperative planning and intraoperative guidance. Compared to traditional imaging modalities such as computed tomography (CT) and magnetic resonance imaging (MRI),ultrasound, an emerging CAOS technology, provides a radiation-free, cost-effective, and portable alternative. While ultrasound offers new opportunities in CAOS, technical shortcomings continue to hinder its translation into surgery. In particular, due to the inherent limitations of ultrasound imaging, B-mode ultrasound typically captures only partial bone surfaces. The inter- and intra-operator variability in ultrasound scanning further increases the complexity of the data. Existing reconstruction methods struggle with such challenging data, leading to increased reconstruction errors and artifacts, such as holes and inflated structures. Effective techniques for accurately reconstructing open bone surfaces from real-world 3D ultrasound volumes remain lacking. We propose UltraBoneUDF, a self-supervised framework specifically designed for reconstructing open bone surfaces from ultrasound data. It learns unsigned distance functions (UDFs) from 3D ultrasound data. In addition, we present a novel loss function based on local tangent plane optimization that substantially improves surface reconstruction quality. UltraBoneUDF and competing models are benchmarked on three open-source datasets and further evaluated through ablation studies. Qualitative results demonstrate the limitations of the state-of-the-art methods. Quantitatively, UltraBoneUDF achieves comparable or lower bi-directional Chamfer distance across three datasets with fewer parameters: 1.60 mm on the UltraBones100k dataset (~25.5% improvement), 0.21 mm on the OpenBoneCT dataset, and 0.18 mm on the ClosedBoneCT dataset.

eess.IV

SonoGym: High Performance Simulation for Challenging Surgical Tasks with Robotic Ultrasound

Ultrasound (US) is a widely used medical imaging modality due to its real-time capabilities, non-invasive nature, and cost-effectiveness. Robotic ultrasound can further enhance its utility by reducing operator dependence and improving access to complex anatomical regions. For this, while deep reinforcement learning (DRL) and imitation learning (IL) have shown potential for autonomous navigation, their use in complex surgical tasks such as anatomy reconstruction and surgical guidance remains limited -- largely due to the lack of realistic and efficient simulation environments tailored to these tasks. We introduce SonoGym, a scalable simulation platform for complex robotic ultrasound tasks that enables parallel simulation across tens to hundreds of environments. Our framework supports realistic and real-time simulation of US data from CT-derived 3D models of the anatomy through both a physics-based and a generative modeling approach. Sonogym enables the training of DRL and recent IL agents (vision transformers and diffusion policies) for relevant tasks in robotic orthopedic surgery by integrating common robotic platforms and orthopedic end effectors. We further incorporate submodular DRL -- a recent method that handles history-dependent rewards -- for anatomy reconstruction and safe reinforcement learning for surgery. Our results demonstrate successful policy learning across a range of scenarios, while also highlighting the limitations of current methods in clinically relevant environments. We believe our simulation can facilitate research in robot learning approaches for such challenging robotic surgery applications. Dataset, codes, and videos are publicly available at https://sonogym.github.io/.

cs.RO

UltraBones100k: A reliable automated labeling method and large-scale dataset for ultrasound-based bone surface extraction

Ultrasound-based bone surface segmentation is crucial in computer-assisted orthopedic surgery. However, ultrasound images have limitations, including a low signal-to-noise ratio, and acoustic shadowing, which make interpretation difficult. Existing deep learning models for bone segmentation rely primarily on costly manual labeling by experts, limiting dataset size and model generalizability. Additionally, the complexity of ultrasound physics and acoustic shadow makes the images difficult for humans to interpret, leading to incomplete labels in anechoic regions and limiting model performance. To advance ultrasound bone segmentation and establish effective model benchmarks, larger and higher-quality datasets are needed. We propose a methodology for collecting ex-vivo ultrasound datasets with automatically generated bone labels, including anechoic regions. The proposed labels are derived by accurately superimposing tracked bone CT models onto the tracked ultrasound images. These initial labels are refined to account for ultrasound physics. A clinical evaluation is conducted by an expert physician specialized on orthopedic sonography to assess the quality of the generated bone labels. A neural network for bone segmentation is trained on the collected dataset and its predictions are compared to expert manual labels, evaluating accuracy, completeness, and F1-score. We collected the largest known dataset of 100k ultrasound images of human lower limbs with bone labels, called UltraBones100k. A Wilcoxon signed-rank test with Bonferroni correction confirmed that the bone alignment after our method significantly improved the quality of bone labeling (p < 0.001). The model trained on UltraBones100k consistently outperforms manual labeling in all metrics, particularly in low-intensity regions (320% improvement in completeness at a distance threshold of 0.5 mm).

eess.IV