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Máté L. Telek

Publications and source records attributed to Máté L. Telek.

15 recordsLinked to original sources

Layered mixed matrices and reaction networks

The purpose of this work is twofold. In the first part, we consider layered mixed matrices introduced by Murota, relate them to existing notions in combinatorial commutative algebra, and investigate the irreducibility of their determinants. Furthermore, for a layered mixed matrix in combinatorial canonical form, we determine the sparsity structure of its inverse. That is, we characterize which entries of the inverse are nonzero. In the second part, we establish for the first time a formal connection between these algebraic results and the theory of buffering structures for reaction networks developed by Mochizuki and Okada. We identify the lattice of buffering structures with the lattice of order ideals of the block poset of the combinatorial canonical form of the associated layered mixed matrix. This allows us to characterize the reducibility of the symbolic Jacobian determinant as a polynomial in the reaction-rate derivatives, as well as the nonzero sensitivity responses of species concentrations to reaction-rate perturbations.

math.CO↗

On the Number of Real Zeros of Random Sparse Polynomial Systems

Consider a random system $\mathfrak{f}_1(x)=0,\ldots,\mathfrak{f}_n(x)=0$ of $n$ random real polynomials in $n$ variables, where each $\mathfrak{f}_k$ has a prescribed set of exponent vectors in a set $A_k\subseteq \mathbb{Z}^n$ of size $t_k$. Assuming that the coefficients of the $\mathfrak{f}_k$ are independent Gaussian of any variance, we prove that the expected number of zeros of the random system in the positive orthant is bounded from above by $4^{-n} \prod_{k=1}^n t_k(t_k-1)$. This result is a probabilisitc version of Kushnirenko's conjecture; it provides a bound that only depends on the number of terms and is independent of their degree.

math.AG↗

Copositivity, discriminants and nonseparable signed supports

We establish a connection between discriminants and copositivity of sparse Laurent polynomials. More generally, we consider signomials, which are defined on the positive orthant by linear combinations of monomials with real exponents, and their signed support, consisting of the support of the signomial and the sign of the coefficients. We provide a criterion to determine whether a given signomial is copositive, that is, only attains nonnegative values, which relies on finding the first intersection point in coefficient space of a path and a signed discriminant: the path contains the coefficient vector of the signomial and preserves its signs, and the signed discriminant encodes the singular signomials with the given signed support. If the signed support satisfies a combinatorial condition termed nonseparability, we additionally show that this intersection consists of one point, and that tracking one path with homotopy continuation suffices to decide upon copositivity. Building on these results, we show that copositive polynomials with nonseparable signed support can always be decomposed into a sum of nonnegative circuit polynomials, generalising thereby previously known supports having this property.

math.AG↗

A note on o-minimal tropicalizations

In this note, we provide several equivalent descriptions of the tropicalization of definable sets in a polynomially bounded o-minimal expansion of a real closed field. We show that the tropicalization can be described in multiple ways: as the image under the valuation map, as the image under the tropicalization map of the archimedean points in the o-minimal spectrum, in terms of initial degenerations of the definable set and initial nonnegativity cones, or via the real tropicalization of polynomials belonging to the corresponding nonnegativity cone. Moreover, we prove analogous results for the fine tropicalization of definable sets, where the valuation map is replaced by the RV sort map, which records not only the valuation of a point but also its angular component.

math.AG↗

Root bounds of vertical systems using tropical geometry

Sparse polynomial systems with vertical coefficient dependencies arise naturally when describing the critical points of optimization problems and, when augmented with linear forms, the steady states of chemical reaction networks. Moreover, any polynomial system is the specialization of such a parametrized system. We prove that the generic number of complex zeros of an augmented vertically parametrized system is the tropical intersection number of a tropical linear space and a classical linear space. In the special case when the matroid of the tropical linear space is cotransversal, we express this number as a mixed volume. We also obtain bounds on the maximal number of positive zeros, which is often the significant number in applications. We derive lower bounds from the number of intersections between positive tropicalizations, and when the positive zeros have toric structure, we provide upper bounds that are simpler and in some cases smaller than the generic root count. The resulting algorithms are implemented in Julia.

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Toric extensions of Pólya's theorem

The classical version of Pólya's theorem provides a simple method for certifying that a homogeneous polynomial of degree d is strictly copositive, that is, it takes only positive values on the nonnegative real orthant. However, this method might fail to detect copositivity of polynomials that are missing certain degree d monomials. In this paper, we present extensions and converses to Pólya's theorem for sparse polynomials, using techniques from positive toric geometry. Furthermore, we explore how this method can be used to study the convergence of Feynman integrals in particle physics.

math.AG↗

Computing positive tropical varieties and lower bounds on the number of positive roots

We present two effective tools for computing the positive tropicalization of algebraic varieties. First, we outline conditions under which the initial ideal can be used to compute the positive tropicalization, offering a real analogue to the Fundamental Theorem of Tropical Geometry. Additionally, under certain technical assumptions, we provide a real version of the Transverse Intersection Theorem. Building on these results, we propose an algorithm to compute a combinatorial bound on the number of positive real roots of a parametrized polynomial equations system. Furthermore, we discuss how this combinatorial bound can be applied to study the number of positive steady states in chemical reaction networks.

math.AG↗

Viro's patchworking and the signed reduced A-discriminant

Computing the isotopy type of a hypersurface, defined as the positive real zero set of a multivariate polynomial, is a challenging problem in real algebraic geometry. We focus on the case where the defining polynomial has combinatorially restricted exponent vectors and fixed coefficient signs, enabling faster computation of the isotopy type. In particular, Viro's patchworking provides a polyhedral complex that has the same isotopy type as the hypersurface, for certain choices of the coefficients. So we present properties of the signed support, focussing mainly on the case of n-variate (n+3)-nomials, that ensure all possible isotopy types can be obtained via patchworking. To prove this, we study the signed reduced A-discriminant and show that it has a simple structure if the signed support satisfies some combinatorial conditions.

math.AG↗

Copositive geometry of Feynman integrals

Copositive matrices and copositive polynomials are objects from optimization. We connect these to the geometry of Feynman integrals in physics. The integral is guaranteed to converge if its kinematic parameters lie in the copositive cone. Pólya's method makes this manifest. We study the copositive cone for the second Symanzik polynomial of any Feynman graph. Its algebraic boundary is described by Landau discriminants.

math.OC↗

Connectivity of Parameter Regions of Multistationarity for Multisite Phosphorylation Networks

The parameter region of multistationarity of a reaction network contains all the parameters for which the associated dynamical system exhibits multiple steady states. Describing this region is challenging and remains an active area of research. In this paper, we concentrate on two biologically relevant families of reaction networks that model multisite phosphorylation and dephosphorylation of a substrate at $n$ sites. For small values of $n$, it had previously been shown that the parameter region of multistationarity is connected. Here, we extend these results and provide a proof that applies to all values of $n$. Our techniques are based on the study of the critical polynomial associated with these reaction networks together with polyhedral geometric conditions of the signed support of this polynomial.

q-bio.MN↗

Binary geometries from pellytopes

Binary geometries have recently been introduced in particle physics in connection with stringy integrals. In this work, we study a class of simple polytopes, called \emph{pellytopes}, whose number of vertices are given by Pell's numbers. We provide a new family of binary geometries determined by pellytopes as conjectured by He--Li--Raman--Zhang. We relate this family to the moduli space of curves by comparing the pellytope to the ABHY associahedron.

math.AG↗

Geometry of the signed support of a multivariate polynomial and Descartes' rule of signs

We investigate the signed support, that is, the set of the exponent vectors and the signs of the coefficients, of a multivariate polynomial $f$. We describe conditions on the signed support ensuring that the semi-algebraic set, denoted as $\{ f < 0 \}$, containing points in the positive real orthant where $f$ takes negative values, has at most one connected component. These results generalize Descartes' rule of signs in the sense that they provide a bound which is independent of the values of the coefficients and the degree of the polynomial. Based on how the exponent vectors lie on the faces of the Newton polytope, we give a recursive algorithm that verifies a sufficient condition for the set $\{ f < 0 \}$ to have one connected component. We apply the algorithm to reaction networks in order to prove that the parameter region of multistationarity of a ubiquitous network comprising phosphorylation cycles is connected.

math.AG↗

Real tropicalization and negative faces of the Newton polytope

In this work, we explore the relation between the tropicalization of a real semi-algebraic set $S = \{ f_1 < 0, \dots , f_k < 0\}$ defined in the positive orthant and the combinatorial properties of the defining polynomials $f_1, \dots, f_k$. We describe a cone that depends only on the face structure of the Newton polytopes of $f_1, \dots ,f_k$ and the signs attained by these polynomials. This cone provides an inner approximation of the real tropicalization, and it coincides with the real tropicalization if $S = \{ f < 0\}$ and the polynomial $f$ has generic coefficients. Furthermore, we show that for a maximally sparse polynomial $f$ the real tropicalization of $S = \{ f < 0\}$ is determined by the outer normal cones of the Newton polytope of $f$ and the signs of its coefficients. Our arguments are valid also for signomials, that is, polynomials with real exponents defined in the positive orthant.

math.AG↗

Topological descriptors of the parameter region of multistationarity: deciding upon connectivity

Switch-like responses arising from bistability have been linked to cell signaling processes and memory. Revealing the shape and properties of the set of parameters that lead to bistability is necessary to understand the underlying biological mechanisms, but is a complex mathematical problem. We present an efficient approach to determine a basic topological property of the parameter region of multistationary, namely whether it is connected or not. The connectivity of this region can be interpreted in terms of the biological mechanisms underlying bistability and the switch-like patterns that the system can create. We provide an algorithm to assert that the parameter region of multistationarity is connected, targeting reaction networks with mass-action kinetics. We show that this is the case for numerous relevant cell signaling motifs, previously described to exhibit bistability. However, we show that for a motif displaying a phosphorylation cycle with allosteric enzyme regulation, the region of multistationarity has two distinct connected components, corresponding to two different, but symmetric, biological mechanisms. The method relies on linear programming and bypasses the expensive computational cost of direct and generic approaches to study parametric polynomial systems. This characteristic makes it suitable for mass-screening of reaction networks.

q-bio.MN↗

On generalizing Descartes' rule of signs to hypersurfaces

We give partial generalizations of the classical Descartes' rule of signs to multivariate polynomials (with real exponents), in the sense that we provide upper bounds on the number of connected components of the complement of a hypersurface in the positive orthant. In particular, we give conditions based on the geometrical configuration of the exponents and the sign of the coefficients that guarantee that the number of connected components where the polynomial attains a negative value is at most one or two. Our results fully cover the cases where such an upper bound provided by the univariate Descartes' rule of signs is one. This approach opens a new route to generalize Descartes' rule of signs to the multivariate case, differing from previous works that aim at counting the number of positive solutions of a system of multivariate polynomial equations.

math.AG↗