arXiv subjects

M. Barone

Publications and source records attributed to M. Barone.

11 recordsLinked to original sources

arXiv2025

Science for Peace and the need for Civil Clauses at universities and civilian research institutions

After the end of World War II, the commitment to confine scientific activities in universities and research institutions to peaceful and civilian purposes has entered, in the form of {\it Civil Clauses}, the charters of many research institutions and universities. In the wake of recent world events, the relevance and scope of such Civil Clauses has been questioned in reports issued by some governments and by the EU Commission, a development that opens the door to a possible blurring of the distinction between peaceful and military research. This paper documents the reflections stimulated by a panel discussion on this issue recently organized by the Science4Peace Forum. We review the adoptions of Civil Clauses in research organizations and institutions in various countries, present evidence of the challenges that are emerging to such Civil Clauses, and collect arguments in favour of maintaining the purely civilian and peaceful focus of public (non-military) research.

physics.soc-ph↗

arXiv2025

Science4Peace: A Plea for Continued Peaceful International Scientific Cooperation (Input to the European Strategy for Particle Physics -- 2026 update)

The European Strategy for Particle Physics (ESPP) - 2026 update is taking place in a turbulent international climate. Many of the norms that have governed relations between states for decades are being broken or challenged. The future progress of science in general, and particle physics in particular, will depend on our ability to maintain peaceful international scientific collaboration in the face of political pressures. We plead that the ESPP 2026 update acknowledge explicitly the importance of peaceful international scientific collaboration, not only for the progress of science, but also as a precious bridge between geopolitical blocs. "Scientific thought is the common heritage of mankind" - Abdus Salam

physics.soc-ph↗

arXiv2024

A Science4Peace initiative: Alleviating the consequences of sanctions in international scientific cooperation

The armed invasion of Ukraine by the Russian Federation has adversely affected the relations between Russia and Western countries. Among other aspects, it has put scientific cooperation and collaboration into question and changed the scientific landscape significantly. Cooperation between some Western institutions and their Russian and Belarusian partners were put on hold after February 24, 2022. The CERN Council decided at its meeting in December 2023 to terminate cooperation agreements with Russia and Belarus that date back a decade. CERN is an international institution with UN observer status, and has so far played a role in international cooperation which was independent of national political strategies. We argue that the Science4Peace idea still has a great value and scientific collaboration between scientists must continue, since fundamental science is by its nature an international discipline. A ban of scientists participating in international cooperation and collaboration is against the traditions, requirements and understanding of science. We call for measures to reactivate the peaceful cooperation of individual scientists on fundamental research in order to stimulate international cooperation for a more peaceful world in the future. Specifically, we plead for finding ways to continue this cooperation through international organizations, such as CERN and JINR.

physics.soc-ph↗

arXiv2023

Beyond a Year of Sanctions in Science

While sanctions in political and economic areas are now part of the standard repertoire of Western countries (not always endorsed by UN mandates), sanctions in science and culture in general are new. Historically, fundamental research as conducted at international research centers such as CERN has long been seen as a driver for peace, and the Science4Peace idea has been celebrated for decades. However, much changed with the war against Ukraine, and most Western science organizations put scientific cooperation with Russia and Belarus on hold immediately after the start of the war in 2022. In addition, common publications and participation in conferences were banned by some institutions, going against the ideal of free scientific exchange and communication. These and other points were the topics of an international virtual panel discussion organized by the Science4Peace Forum together with the "Natural Scientists Initiative - Responsibility for Peace and Sustainability" (NatWiss e.V.) in Germany and the journal "Wissenschaft und Frieden" (W&F) (see the Figure). Fellows from the Hamburg Institute for Peace Research and Security Policy (IFSH), scientists collaborating with the large physics research institutes DESY and CERN, as well as from climate and futures researchers were represented on the panel. In this Dossier we document the panel discussion, and give additional perspectives. The authors of the individual sections present their personal reflections, which should not be taken as implying that they are endorsed by the Science4Peace Forum or any other organizations. It is regrettable that some colleagues who expressed support for this document felt that it would be unwise for them to co-sign it.

physics.soc-ph↗

arXiv2021

Computationally driven discovery of SARS-CoV-2 Mpro inhibitors: from design to experimental validation

We report a fast-track computationally-driven discovery of new SARS-CoV2 Main Protease (M$^{pro}$) inhibitors whose potency range from mM for initial non-covalent ligands to sub-$\mu$M for the final covalent compound (IC50=830 +/- 50 nM). The project extensively relied on high-resolution all-atom molecular dynamics simulations and absolute binding free energy calculations performed using the polarizable AMOEBA force field. The study is complemented by extensive adaptive sampling simulations that are used to rationalize the different ligands binding poses through the explicit reconstruction of the ligand-protein conformation spaces. Machine Learning predictions are also performed to predict selected compound properties. While simulations extensively use High Performance Computing to strongly reduce time-to-solution, they were systematically coupled to Nuclear Magnetic Resonance experiments to drive synthesis and to in vitro characterization of compounds. Such study highlights the power of in silico strategies that rely on structure-based approaches for drug design and allows to address the protein conformational multiplicity problem. The proposed fluorinated tetrahydroquinolines open routes for further optimization of M$^{pro}$ inhibitors towards low nM affinities.

physics.chem-ph↗

arXiv2009

Einstein and the mystery of eternity of life

While Special and General Relativity are well known by a very large number of people, Einstein's religious convinctions are almost ignored. The paper focuses on what was his view about immortality. Einstein believed in Spinoza's view of God and in cosmic religion. Since the Special Relativity implies a kind of superdeterminism with the future completely determined,that can be taken as ontological proof for the non-Existence of an hypothetical God. Because of that K.Popper in a private conversation with him said: "You are Parmenides". Einstein's Pantheism was in contrast with the non-Euclidean universe of Special Relativity. In conclusion the interest in our times of his Weltanschaung will be taken in consideration.

physics.gen-ph↗

arXiv2005

Phenomenological study of the atypical heavy flavor production observed at the Fermilab Tevatron

We address known discrepancies between the heavy flavor properties of jets produced at the Tevatron collider and the prediction of conventional-QCD simulations. In this study, we entertain the possibility that these effects are real and due to new physics. We show that all anomalies can be simultaneously fitted by postulating the additional pair production of light bottom squarks with a 100% semileptonic branching fraction.

hep-ex↗

arXiv2005

Search for narrow resonances below the Upsilon mesons

We have investigated the invariant mass spectrum of dimuons collected by the CDF experiment during the 1992-1995 run of the Fermilab Tevatron collider to improve the limit on the existence of narrow resonances set by the experiments at the SPEAR e+e- collider. In the mass range 6.3-9.0 GeV/c^2, we derive 90% upper credible limits to the ratio of the production cross section times muonic branching fraction of possible narrow resonances to that of the Y(1S) meson. In this mass range, the average limit varies from 1.7 to 0.5%. This limit is much worse at the mass of 7.2 GeV/c^2 due to an excess of 250+-61 events with a width consistent with the detector resolution.

hep-ex↗

arXiv2005

Study of sequential semileptonic decays of b hadrons produced at the Tevatron

We present a study of rates and kinematical properties of lepton pairs contained in central jets with transverse energy E_T > 15 GeV that are produced at the Fermilab Tevatron collider. We compare the data to a QCD prediction based on the HERWIG and QQ Monte Carlo generator programs.We find that the data are poorly described by the simulation, in which sequential semileptonic decays of single b quarks (b --> l c X with c --> l s X) are the major source of such lepton pairs.

hep-ex↗

arXiv2004

Comparison of Three-jet Events in Proton-Antiproton Collisions at Center-of-mass Energy 1.8 TeV to Predictions from a Next-to-leading Order QCD Calculation

The properties of three-jet events with total transverse energy greater than 320 GeV and individual jet energy greater than 20 GeV have been analyzed and compared to absolute predictions from a next-to-leading order (NLO) perturbative QCD calculation. These data, of integrated luminosity 86 pb^-1, were recorded by the CDF Experiment for proton-antiproton collisions at sqrt{s}=1.8 TeV. This study tests a model of higher order QCD processes that result in gluon emission and can be used to estimate the magnitude of the contribution of processes higher than NLO. The total cross section is measured to be 466 +/- 3(stat.)^{+207}_{-70}(syst.) pb. The differential cross section is furthermore measured for all kinematically accessible regions of the Dalitz plane, including those for which the theoretical prediction is unreliable. While the measured cross section is consistent with the theoretical prediction in magnitude, the two differ somewhat in shape in the Dalitz plane.

hep-ex↗

arXiv1998

Three-Flavour Neutrino-Mixing Implications of the LSND Result

The LSND result is shown to fit into a minimal three-flavour neutrino-mixing scenario capable of describing all known experimental facts provided the large Delta M^2 = m_3^2 - m_2^2 \sim m_3^2 - m_1^2 lies in the range 2.5 x 10^{-1} < Delta M^2 < 3.0 eV^2. In this range the value of P_{μτ} is expected to be about 5% or larger.

hep-ph↗