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M. Kavousanakis

Publications and source records attributed to M. Kavousanakis.

4 recordsLinked to original sources

Blowup of Multi-Peaked Waveforms in the Two-Dimensional Nonlinear Schroedinger Model

In the present work, we explore the self-focusing and resulting collapse of two-dimensional waveforms involving multiple pulses in a nonlinear Schroedinger equation with a general power-law nonlinearity. We find that a wide range of multi-peaked states bifurcate from the critical threshold of the cubic nonlinearity, thus representing ``bifurcations from infinity'', i.e., the relevant pulses start at infinite distance in the critical limit and draw nearer, as the nonlinearity exponent increases past that threshold. We identify the resulting ``interacting particle system'' as amounting to a force balance between the exponentially interacting tails (modulated by a suitable power law) and a linear phase-induced force. The equilibria emerging from this force balance are found to be in excellent agreement with the identified steady states of the partial differential equation. The spectral stability of multi-peaked configurations is analyzed, leading to the conclusion that all the relevant states are less stable than the single-peak collapsing solution whose stability was analyzed earlier. Indeed, we reveal both symmetry-breaking, as well as motion-inducing destabilizing dynamics, with the former ones among them being dominant and ultimately leading to a single dominant collapse spot. Moreover, we characterize systematically both the real and imaginary eigenvalues of multi-peaked configurations, partitioning them in groups of different sizes, described by powers of the solution's blowup rate G.

nlin.PS

Self-similar blow-up solutions in the generalized Korteweg-de Vries equation: Spectral analysis, normal form and asymptotics

In the present work we revisit the problem of the generalized Korteweg-de Vries equation parametrically, as a function of the relevant nonlinearity exponent, to examine the emergence of blow-up solutions, as traveling waveforms lose their stability past a critical point of the relevant parameter $p$, here at $p=5$. We provide a {\it normal form} of the associated collapse dynamics and illustrate how this captures the collapsing branch bifurcating from the unstable traveling branch. We also systematically characterize the linearization spectrum of not only the traveling states, but importantly of the emergent collapsing waveforms in the so-called co-exploding frame where these waveforms are identified as stationary states. This spectrum, in addition to two positive real eigenvalues which are shown to be associated with the symmetries of translation and scaling invariance of the original (non-exploding) frame features complex patterns of negative eigenvalues that we also fully characterize. We show that the phenomenology of the latter is significantly affected by the boundary conditions and is far more complicated than in the corresponding symmetric Laplacian case of the nonlinear Schr{ö}dinger problem that has recently been explored. In addition, we explore the dynamics of the unstable solitary waves for $p>5$ in the co-exploding frame.

nlin.PS

Assessment of intra-tumor heterogeneity in a two-dimensional vascular tumor growth model

We present a two-dimensional continuum model of tumor growth, which treats the tissue as a composition of six distinct fluid phases; their dynamics are governed by the equations of mass and momentum conservation. Our model divides the cancer cells phase into two sub-phases depending on their maturity state. The same approach is also applied for the vasculature phase, which is divided into young sprouts (products of angiogenesis), and fully formed-mature vessels. The remaining two phases correspond to healthy cells and extracellular material (ECM). Furthermore, the model foresees the existence of nutrient chemical species, which are transferred within the tissue through diffusion or supplied by the vasculature (blood vessels). The model is numerically solved with the Finite Elements Method and computations are performed with the commercial software Comsol Multiphysics. The numerical simulations predict that mature cancer cells are well separated from young cancer cells, which form a protective shield for the growing tumor. We study the effect of different mitosis and death rates for mature and young cancer cells on the tumor growth rate, and predict accelerated rates when the mitosis rate of young cancer cells is higher compared to mature cancer cells.

q-bio.PE

Localized Breathing Modes in Granular Crystals with Defects

We investigate nonlinear localized modes at light-mass impurities in a one-dimensional, strongly-compressed chain of beads under Hertzian contacts. Focusing on the case of one or two such "defects", we analyze the problem's linear limit to identify the system eigenfrequencies and the linear defect modes. We then examine the bifurcation of nonlinear defect modes from their linear counterparts and study their linear stability in detail. We identify intriguing differences between the case of impurities in contact and ones that are not in contact. We find that the former bears similarities to the single defect case, whereas the latter features symmetry-breaking bifurcations with interesting static and dynamic implications.

nlin.PS