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M. N. H. Rashad

Publications and source records attributed to M. N. H. Rashad.

11 recordsLinked to original sources

Divergent Clinical Equivalence Findings from DVH and NTCP Metrics for Alternative OAR Delineations with Increasing Setup Variability in Head-and-Neck Radiotherapy

Purpose: This study quantifies the variation in dose-volume histogram (DVH) and normal tissue complication probability (NTCP) metrics for head-and-neck (HN) cancer patients when alternative organ-at-risk (OAR) delineations are used for treatment planning and for treatment plan evaluation. We particularly focus on the effects of daily patient positioning/setup variations (SV) in relation to treatment technique and delineation variability. Materials and Methods: We generated two-arc VMAT, 5-beam IMRT, and 9-beam IMRT treatment plans for a cohort of 209 HN patients. These plans incorporated five different OAR delineation sets, including manual and four automated algorithms. Each treatment plan was assessed under various simulated per-fraction patient setup uncertainties, evaluating the potential clinical impacts through DVH and NTCP metrics. Results: The study demonstrates that increasing setup variability generally reduces differences in DVH metrics between alternative delineations. However, in contrast, differences in NTCP metrics tend to increase with higher setup variability. This pattern is observed consistently across different treatment plans and delineator combinations, illustrating the intricate relationship between SV and delineation accuracy. Additionally, the need for delineation accuracy in treatment planning is shown to be case-specific and dependent on factors beyond geometric variations. Conclusions: The findings highlight the necessity for comprehensive quality assurance programs in radiotherapy, incorporating both dosimetric impact analysis and geometric variation assessment to ensure optimal delineation quality. The study emphasizes the complex dynamics of treatment planning in radiotherapy, advocating for personalized, case-specific strategies in clinical practice to enhance patient care quality and efficacy in the face of varying SV and delineation accuracies.

physics.med-ph↗

New Measurements of the Beam-Normal Single Spin Asymmetry in Elastic Electron Scattering Over a Range of Spin-0 Nuclei

We report precision determinations of the beam normal single spin asymmetries ($A_n$) in the elastic scattering of 0.95 and 2.18~GeV electrons off $^{12}$C, $^{40}$Ca, $^{48}$Ca, and $^{208}$Pb at very forward angles where the most detailed theoretical calculations have been performed. The first measurements of $A_n$ for $^{40}$Ca and $^{48}$Ca are found to be similar to that of $^{12}$C, consistent with expectations thus demonstrating the validity of theoretical calculations for nuclei with Z~$\leq20$. We also report $A_n$ for $^{208}$Pb at two new momentum transfers (Q$^2$) extending the previous measurement. Our new data confirm the surprising result previously reported, with all three data points showing significant disagreement with the results from the $Z\leq 20$ nuclei. These data confirm our basic understanding of the underlying dynamics that govern $A_n$ for nuclei containing $\lesssim 50$ nucleons, but point to the need for further investigation to understand the unusual $A_n$ behaviour discovered for scattering off $^{208}$Pb.

nucl-ex↗

Precision Determination of the Neutral Weak Form Factor of $^{48}$Ca

We report a precise measurement of the parity-violating asymmetry $A_{\rm PV}$ in the elastic scattering of longitudinally polarized electrons from $^{48}{\rm Ca}$. We measure $A_{\rm PV} =2668\pm 106\ {\rm (stat)}\pm 40\ {\rm (syst)}$ parts per billion, leading to an extraction of the neutral weak form factor $F_{\rm W} (q=0.8733$ fm$^{-1}) = 0.1304 \pm 0.0052 \ {\rm (stat)}\pm 0.0020\ {\rm (syst)}$ and the charge minus the weak form factor $F_{\rm ch} - F_{\rm W} = 0.0277\pm 0.0055$. The resulting neutron skin thickness $R_n-R_p=0.121 \pm 0.026\ {\rm (exp)} \pm 0.024\ {\rm (model)}$~fm is relatively thin yet consistent with many model calculations. The combined CREX and PREX results will have implications for future energy density functional calculations and on the density dependence of the symmetry energy of nuclear matter.

nucl-ex↗

Deeply virtual Compton scattering cross section at high Bjorken $x_B$

We report high-precision measurements of the Deeply Virtual Compton Scattering (DVCS) cross section at high values of the Bjorken variable $x_B$. DVCS is sensitive to the Generalized Parton Distributions of the nucleon, which provide a three-dimensional description of its internal constituents. Using the exact analytic expression of the DVCS cross section for all possible polarization states of the initial and final electron and nucleon, and final state photon, we present the first experimental extraction of all four helicity-conserving Compton Form Factors (CFFs) of the nucleon as a function of $x_B$, while systematically including helicity flip amplitudes. In particular, the high accuracy of the present data demonstrates sensitivity to some very poorly known CFFs.

hep-ph↗

Deep exclusive electroproduction of $π^0$ at high $Q^2$ in the quark valence regime

We report measurements of the exclusive neutral pion electroproduction cross section off protons at large values of $x_B$ (0.36, 0.48 and 0.60) and $Q^2$ (3.1 to 8.4 GeV$^2$) obtained from Jefferson Lab Hall A experiment E12-06-014. The corresponding structure functions $dσ_L/dt+εdσ_T/dt$, $dσ_{TT}/dt$, $dσ_{LT}/dt$ and $dσ_{LT'}/dt$ are extracted as a function of the proton momentum transfer $t-t_{min}$. The results suggest the amplitude for transversely polarized virtual photons continues to dominate the cross-section throughout this kinematic range. The data are well described by calculations based on transversity Generalized Parton Distributions coupled to a helicity flip Distribution Amplitude of the pion, thus providing a unique way to probe the structure of the nucleon.

hep-ex↗

Deeply virtual Compton scattering off the neutron

The three-dimensional structure of nucleons (protons and neutrons) is embedded in so-called generalized parton distributions, which are accessible from deeply virtual Compton scattering. In this process, a high energy electron is scattered off a nucleon by exchanging a virtual photon. Then, a highly-energetic real photon is emitted from one of the quarks inside the nucleon, which carries information on the quark's transverse position and longitudinal momentum. By measuring the cross-section of deeply virtual Compton scattering, Compton form factors related to the generalized parton distributions can be extracted. Here, we report the observation of unpolarized deeply virtual Compton scattering off a deuterium target. From the measured photon-electroproduction cross-sections, we have extracted the cross-section of a quasi-free neutron and a coherent deuteron. Due to the approximate isospin symmetry of quantum chromodynamics, we can determine the contributions from the different quark flavours to the helicity-conserved Compton form factors by combining our measurements with previous ones probing the proton's internal structure. These results advance our understanding of the description of the nucleon structure, which is important to solve the proton spin puzzle.

hep-ph↗

Accurate Determination of the Neutron Skin Thickness of $^{208}$Pb through Parity-Violation in Electron Scattering

We report a precision measurement of the parity-violating asymmetry $A_{PV}$ in the elastic scattering of longitudinally polarized electrons from $^{208}$Pb. We measure $A_{PV}=550\pm 16 {\rm (stat)}\pm 8\ {\rm (syst)}$ parts per billion, leading to an extraction of the neutral weak form factor $F_W(Q^2 = 0.00616\ {\rm GeV}^2) = 0.368 \pm 0.013$. Combined with our previous measurement, the extracted neutron skin thickness is $R_n-R_p=0.283 \pm 0.071$~fm. The result also yields the first significant direct measurement of the interior weak density of $^{208}$Pb: $ρ^0_W = -0.0796\pm0.0036\ {\rm (exp.)}\pm0.0013\ {\rm (theo.)}\ {\rm fm}^{-3}$ leading to the interior baryon density $ρ^0_b = 0.1480\pm0.0036\ {\rm (exp.)}\pm0.0013\ {\rm (theo.)}\ {\rm fm}^{-3}$. The measurement accurately constrains the density dependence of the symmetry energy of nuclear matter near saturation density, with implications for the size and composition of neutron stars.

nucl-ex↗

Probing few-body nuclear dynamics via 3H and 3He (e,e'p)pn cross-section measurements

We report the first measurement of the \eep three-body breakup reaction cross sections in helium-3 ($^3$He) and tritium ($^3$H) at large momentum transfer ($\langle Q^2 \rangle \approx 1.9$ (GeV/c)$^2$) and $x_B>1$ kinematics, where the cross section should be sensitive to quasielastic (QE) scattering from single nucleons. The data cover missing momenta $40 \le p_{miss} \le 500$ MeV/c that, in the QE limit with no rescattering, equals the initial momentum of the probed nucleon. The measured cross sections are compared with state-of-the-art ab-initio calculations. Overall good agreement, within $\pm20\%$, is observed between data and calculations for the full $p_{miss}$ range for $^3$H and for $100 \le p_{miss} \le 350$ MeV/c for $^3$He. Including the effects of rescattering of the outgoing nucleon improves agreement with the data at $p_{miss} > 250$ MeV/c and suggests contributions from charge-exchange (SCX) rescattering. The isoscalar sum of $^3$He plus $^3$H, which is largely insensitive to SCX, is described by calculations to within the accuracy of the data over the entire $p_{miss}$ range. This validates current models of the ground state of the three-nucleon system up to very high initial nucleon momenta of $500$ MeV/c.

nucl-ex↗

A Glimpse of Gluons through Deeply Virtual Compton Scattering on the Proton

The proton is composed of quarks and gluons, bound by the most elusive mechanism of strong interaction called confinement. In this work, the dynamics of quarks and gluons are investigated using deeply virtual Compton scattering (DVCS): produced by a multi-GeV electron, a highly virtual photon scatters off the proton which subsequently radiates a high energy photon. Similarly to holography, measuring not only the magnitude but also the phase of the DVCS amplitude allows to perform 3D images of the internal structure of the proton. The phase is made accessible through the quantum-mechanical interference of DVCS with the Bethe-Heitler (BH) process, in which the final photon is emitted by the electron rather than the proton. We report herein the first full determination of the BH-DVCS interference by exploiting the distinct energy dependences of the DVCS and BH amplitudes. In the high energy regime where the scattering process is expected to occur off a single quark in the proton, these accurate measurements show an intriguing sensitivity to gluons, the carriers of the strong interaction.

hep-ex↗

Rosenbluth separation of the $π^0$ Electroproduction Cross Section off the Neutron

We report the first longitudinal/transverse separation of the deeply virtual exclusive $π^0$ electroproduction cross section off the neutron and coherent deuteron. The corresponding four structure functions $dσ_L/dt$, $dσ_T/dt$, $dσ_{LT}/dt$ and $dσ_{TT}/dt$ are extracted as a function of the momentum transfer to the recoil system at $Q^2$=1.75 GeV$^2$ and $x_B$=0.36. The $ed \to edπ^0$ cross sections are found compatible with the small values expected from theoretical models. The $en \to enπ^0$ cross sections show a dominance from the response to transversely polarized photons, and are in good agreement with calculations based on the transversity GPDs of the nucleon. By combining these results with previous measurements of $π^0$ electroproduction off the proton, we present a flavor decomposition of the $u$ and $d$ quark contributions to the cross section.

hep-ex↗

Rosenbluth separation of the $π^0$ electroproduction cross section

We present deeply virtual $π^0$ electroproduction cross-section measurements at $x_B$=0.36 and three different $Q^2$--values ranging from 1.5 to 2 GeV$^2$, obtained from experiment E07-007 that ran in the Hall A at Jefferson Lab. The Rosenbluth technique was used to separate the longitudinal and transverse responses. Results demonstrate that the cross section is dominated by its transverse component, and thus is far from the asymptotic limit predicted by perturbative Quantum Chromodynamics. An indication of a non-zero longitudinal contribution is provided by the interference term $σ_{LT}$ also measured. Results are compared with several models based on the leading twist approach of Generalized Parton Distributions (GPDs). In particular, a fair agreement is obtained with models where the scattering amplitude is described by a convolution of chiral-odd (transversity) GPDs of the nucleon with the twist-3 pion distribution amplitude. Therefore, neutral pion electroproduction may offer the exciting possibility of accessing transversity GPDs through experiment.

hep-ex↗