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M. S. Barbosa

Publications and source records attributed to M. S. Barbosa.

4 recordsLinked to original sources

On the Importance of Hubs in Hopfield Complex Neuronal Networks under Attack

The organizational principles behind the connectivity of a complex network are known to influence its behavior. In this work we investigate, using the Hopfield model, the influence of the network architecture on the performance for associative recall while the network is under hub and edge attack. We show, by using four different attack strategies, that although the importance of hubs is more definite for Barabási-Albert neuronal networks, the random removal of the same amount of edges as in a hub may imply a greater reduction of memory recall.

cond-mat.dis-nn

Extended morphometric analysis of neuronal cells with Minkowski valuations

Minkowski valuations provide a systematic framework for quantifying different aspects of morphology. In this paper we apply vector- and tensor-valued Minkowski valuations to neuronal cells from the cat's retina in order to describe their morphological structure in a comprehensive way. We introduce the framework of Minkowski valuations, discuss their implementation for neuronal cells and show how they can discriminate between cells of different types.

cond-mat.dis-nn

On the Potential of the Excluded Volume and Auto-Correlation as Neuromorphometric Descriptors

This work investigates at what degree two neuromorphometric measurements, namely the autocorrelation and the excluded volume of a neuronal cell can influence the characterization and classification of such a type of cells. While the autocorrelation function presents good potential for quantifying the dendrite-dendrite connectivity of cells in mosaic tilings, the excluded volume, i.e. the amount of the surround space which is geometrically not accessible to an axon or dendrite, provides a complementary characterization of the cell connectivity. The potential of such approaches is illustrated with respect to real neuronal cells.

cond-mat.stat-mech

Characterizing neuromorphologic alterations with additive shape functionals

The complexity of a neuronal cell shape is known to be related to its function. Specifically, among other indicators, a decreased complexity in the dendritic trees of cortical pyramidal neurons has been associated with mental retardation. In this paper we develop a procedure to address the characterization of morphological changes induced in cultured neurons by over-expressing a gene involved in mental retardation. Measures associated with the multiscale connectivity, an additive image functional, are found to give a reasonable separation criterion between two categories of cells. One category consists of a control group and two transfected groups of neurons, and the other, a class of cat ganglionary cells. The reported framework also identified a trend towards lower complexity in one of the transfected groups. Such results establish the suggested measures as an effective descriptors of cell shape.

q-bio.QM