arXiv subjects

Mahmudul Hasan

Publications and source records attributed to Mahmudul Hasan.

46 records · Page 3Linked to original sources

arXiv2020

Improving Multimodal Accuracy Through Modality Pre-training and Attention

Training a multimodal network is challenging and it requires complex architectures to achieve reasonable performance. We show that one reason for this phenomena is the difference between the convergence rate of various modalities. We address this by pre-training modality-specific sub-networks in multimodal architectures independently before end-to-end training of the entire network. Furthermore, we show that the addition of an attention mechanism between sub-networks after pre-training helps identify the most important modality during ambiguous scenarios boosting the performance. We demonstrate that by performing these two tricks a simple network can achieve similar performance to a complicated architecture that is significantly more expensive to train on multiple tasks including sentiment analysis, emotion recognition, and speaker trait recognition.

cs.AI↗

arXiv2020

Virtual Screening of Plant Metabolites against Main protease, RNA-dependent RNA polymerase and Spike protein of SARS-CoV-2: Therapeutics option of COVID-19

Covid-19, a serious respiratory complications caused by SARS-CoV-2 has become one of the global threat to human healthcare system. The present study evaluated the possibility of plant originated approved 117 therapeutics against the main protease protein (MPP), RNA-dependent RNA polymerase (RdRp) and spike protein (S) of SARS-CoV-2 including drug surface analysis by using molecular docking through drug repurposing approaches. The molecular interaction study revealed that Rifampin (-16.3 kcal/mol) were topmost inhibitor of MPP where Azobechalcone were found most potent plant therapeutics for blocking the RdRp (-15.9 kcal /mol) and S (-14.4 kcal/mol) protein of SARS-CoV-2. After the comparative analysis of all docking results, Azobechalcone, Rifampin, Isolophirachalcone, Tetrandrine and Fangchinoline were exhibited as the most potential inhibitory plant compounds for targeting the key proteins of SARS-CoV-2. However, amino acid positions; H41, C145, and M165 of MPP played crucial roles for the drug surface interaction where F368, L371, L372, A375, W509, L514, Y515 were pivotal for RdRP. In addition, the drug interaction surface of S proteins also showed similar patterns with all of its maximum inhibitors. ADME analysis also strengthened the possibility of screened plant therapeutics as the potent drug candidates against SARS-C with the highest drug friendliness.

q-bio.GN↗

arXiv2020

Prediction of potential inhibitors for RNA-dependent RNA polymerase of SARS-CoV-2 using comprehensive drug repurposing and molecular docking approach

The pandemic prevalence of COVID-19 has become a very serious global health issue. Scientists all over the world have been heavily invested in the discovery of a drug to combat SARS-CoV-2. It has been found that RNA-dependent RNA Polymerase (RdRp) plays a crucial role in SARS-CoV-2 replication, and thus could be a potential drug target. Here, comprehensive computational approaches including drug repurposing and molecular docking were employed to predict an effective drug candidate targeting RdRp of SARS-CoV-2. This study revealed that Rifabutin, Rifapentine, Fidaxomicin, 7-methyl-guanosine-5'-triphosphate-5'-guanosine and Ivermectin have a potential inhibitory interaction with RdRp of SARS-CoV-2, and could be effective drugs for COVID-19. In addition, virtual screening of the compounds from ZINC database also allowed the prediction of two compounds (ZINC09128258 and ZINC 09883305) with pharmacophore features that interact effectively with RdRp of SARS-CoV-2; indicating their potentiality as effective inhibitors of the enzyme. Furthermore, ADME analysis along with analysis of toxicity was also investigated to check the pharmacokinetics and drug-likeness properties of the two compounds. Comparative structural analysis of protein-inhibitor complexes revealed that positions of the amino acid Y32, K47, Y122, Y129, H133, N138, D140, T141, S709 and N781 are crucial for drug surface hotspot in the RdRp of SARS-CoV-2.

q-bio.BM↗

arXiv2019

Comparisonal study of Deep Learning approaches on Retinal OCT Image

In medical science, the use of computer science in disease detection and diagnosis is gaining popularity. Previously, the detection of disease used to take a significant amount of time and was less reliable. Machine learning (ML) techniques employed in recent biomedical researches are making revolutionary changes by gaining higher accuracy with more concise timing. At present, it is even possible to automatically detect diseases from the scanned images with the help of ML. In this research, we have taken such an attempt to detect retinal diseases from optical coherence tomography (OCT) X-ray images. Here, we propose a deep learning (DL) based approach in detecting retinal diseases from OCT images which can identify three conditions of the retina. Four different models used in this approach are compared with each other. On the test set, the detection accuracy is 98.00\% for a vanilla convolutional neural network (CNN) model, 99.07\% for Xception model, 97.00\% for ResNet50 model, and 99.17\% for MobileNetV2 model. The MobileNetV2 model acquires the highest accuracy, and the closest to the highest is the Xception model. The proposed approach has a potential impact on creating a tool for automatically detecting retinal diseases.

eess.IV↗

arXiv2019

Context-Aware Query Selection for Active Learning in Event Recognition

Activity recognition is a challenging problem with many practical applications. In addition to the visual features, recent approaches have benefited from the use of context, e.g., inter-relationships among the activities and objects. However, these approaches require data to be labeled, entirely available beforehand, and not designed to be updated continuously, which make them unsuitable for surveillance applications. In contrast, we propose a continuous-learning framework for context-aware activity recognition from unlabeled video, which has two distinct advantages over existing methods. First, it employs a novel active-learning technique that not only exploits the informativeness of the individual activities but also utilizes their contextual information during query selection; this leads to significant reduction in expensive manual annotation effort. Second, the learned models can be adapted online as more data is available. We formulate a conditional random field model that encodes the context and devise an information-theoretic approach that utilizes entropy and mutual information of the nodes to compute the set of most informative queries, which are labeled by a human. These labels are combined with graphical inference techniques for incremental updates. We provide a theoretical formulation of the active learning framework with an analytic solution. Experiments on six challenging datasets demonstrate that our framework achieves superior performance with significantly less manual labeling.

cs.CV↗

arXiv2018

Recurrent Residual Convolutional Neural Network based on U-Net (R2U-Net) for Medical Image Segmentation

Deep learning (DL) based semantic segmentation methods have been providing state-of-the-art performance in the last few years. More specifically, these techniques have been successfully applied to medical image classification, segmentation, and detection tasks. One deep learning technique, U-Net, has become one of the most popular for these applications. In this paper, we propose a Recurrent Convolutional Neural Network (RCNN) based on U-Net as well as a Recurrent Residual Convolutional Neural Network (RRCNN) based on U-Net models, which are named RU-Net and R2U-Net respectively. The proposed models utilize the power of U-Net, Residual Network, as well as RCNN. There are several advantages of these proposed architectures for segmentation tasks. First, a residual unit helps when training deep architecture. Second, feature accumulation with recurrent residual convolutional layers ensures better feature representation for segmentation tasks. Third, it allows us to design better U-Net architecture with same number of network parameters with better performance for medical image segmentation. The proposed models are tested on three benchmark datasets such as blood vessel segmentation in retina images, skin cancer segmentation, and lung lesion segmentation. The experimental results show superior performance on segmentation tasks compared to equivalent models including U-Net and residual U-Net (ResU-Net).

cs.CV↗

arXiv2018

Handwritten Bangla Character Recognition Using The State-of-Art Deep Convolutional Neural Networks

In spite of advances in object recognition technology, Handwritten Bangla Character Recognition (HBCR) remains largely unsolved due to the presence of many ambiguous handwritten characters and excessively cursive Bangla handwritings. Even the best existing recognizers do not lead to satisfactory performance for practical applications related to Bangla character recognition and have much lower performance than those developed for English alpha-numeric characters. To improve the performance of HBCR, we herein present the application of the state-of-the-art Deep Convolutional Neural Networks (DCNN) including VGG Network, All Convolution Network (All-Conv Net), Network in Network (NiN), Residual Network, FractalNet, and DenseNet for HBCR. The deep learning approaches have the advantage of extracting and using feature information, improving the recognition of 2D shapes with a high degree of invariance to translation, scaling and other distortions. We systematically evaluated the performance of DCNN models on publicly available Bangla handwritten character dataset called CMATERdb and achieved the superior recognition accuracy when using DCNN models. This improvement would help in building an automatic HBCR system for practical applications.

cs.CV↗

arXiv2017

Improved Inception-Residual Convolutional Neural Network for Object Recognition

Machine learning and computer vision have driven many of the greatest advances in the modeling of Deep Convolutional Neural Networks (DCNNs). Nowadays, most of the research has been focused on improving recognition accuracy with better DCNN models and learning approaches. The recurrent convolutional approach is not applied very much, other than in a few DCNN architectures. On the other hand, Inception-v4 and Residual networks have promptly become popular among computer the vision community. In this paper, we introduce a new DCNN model called the Inception Recurrent Residual Convolutional Neural Network (IRRCNN), which utilizes the power of the Recurrent Convolutional Neural Network (RCNN), the Inception network, and the Residual network. This approach improves the recognition accuracy of the Inception-residual network with same number of network parameters. In addition, this proposed architecture generalizes the Inception network, the RCNN, and the Residual network with significantly improved training accuracy. We have empirically evaluated the performance of the IRRCNN model on different benchmarks including CIFAR-10, CIFAR-100, TinyImageNet-200, and CU3D-100. The experimental results show higher recognition accuracy against most of the popular DCNN models including the RCNN. We have also investigated the performance of the IRRCNN approach against the Equivalent Inception Network (EIN) and the Equivalent Inception Residual Network (EIRN) counterpart on the CIFAR-100 dataset. We report around 4.53%, 4.49% and 3.56% improvement in classification accuracy compared with the RCNN, EIN, and EIRN on the CIFAR-100 dataset respectively. Furthermore, the experiment has been conducted on the TinyImageNet-200 and CU3D-100 datasets where the IRRCNN provides better testing accuracy compared to the Inception Recurrent CNN (IRCNN), the EIN, and the EIRN.

cs.CV↗

arXiv2017

Inception Recurrent Convolutional Neural Network for Object Recognition

Deep convolutional neural networks (DCNNs) are an influential tool for solving various problems in the machine learning and computer vision fields. In this paper, we introduce a new deep learning model called an Inception- Recurrent Convolutional Neural Network (IRCNN), which utilizes the power of an inception network combined with recurrent layers in DCNN architecture. We have empirically evaluated the recognition performance of the proposed IRCNN model using different benchmark datasets such as MNIST, CIFAR-10, CIFAR- 100, and SVHN. Experimental results show similar or higher recognition accuracy when compared to most of the popular DCNNs including the RCNN. Furthermore, we have investigated IRCNN performance against equivalent Inception Networks and Inception-Residual Networks using the CIFAR-100 dataset. We report about 3.5%, 3.47% and 2.54% improvement in classification accuracy when compared to the RCNN, equivalent Inception Networks, and Inception- Residual Networks on the augmented CIFAR- 100 dataset respectively.

cs.CV↗

arXiv2016

Learning Temporal Regularity in Video Sequences

Perceiving meaningful activities in a long video sequence is a challenging problem due to ambiguous definition of 'meaningfulness' as well as clutters in the scene. We approach this problem by learning a generative model for regular motion patterns, termed as regularity, using multiple sources with very limited supervision. Specifically, we propose two methods that are built upon the autoencoders for their ability to work with little to no supervision. We first leverage the conventional handcrafted spatio-temporal local features and learn a fully connected autoencoder on them. Second, we build a fully convolutional feed-forward autoencoder to learn both the local features and the classifiers as an end-to-end learning framework. Our model can capture the regularities from multiple datasets. We evaluate our methods in both qualitative and quantitative ways - showing the learned regularity of videos in various aspects and demonstrating competitive performance on anomaly detection datasets as an application.

cs.CV↗