SearcharxivSearch

arXiv subjects

Makito Oku

Publications and source records attributed to Makito Oku.

3 recordsLinked to original sources

Revisiting the Brunner-Munzel test from the viewpoint of local linear approximation

The Brunner-Munzel (BM) test is a nonparametric test for two independent samples that evaluates whether observations from one group tend to be greater than observations from another group, or vice versa. The BM test has a broader scope of application than the Mann-Whitney $U$ test because it does not assume equal variances between the two groups. However, the meaning of the BM test statistic is difficult to understand intuitively, which may be one of the factors hindering the widespread use of the BM test. To alleviate this problem, in this paper, I introduce an alternative interpretation of the BM test statistic from the viewpoint of local linear approximation. It is shown that the variance estimator for the sample stochastic superiority used in the BM test can be derived using local linear approximation, in which the influence of each observation on the sample stochastic superiority is assumed to be additive. This simple interpretation will help practitioners decide to use the BM test without hesitation.

math.ST

Designing efficient interventions for pre-disease states using control theory

To extend healthy life expectancy in an aging society, it is crucial to prevent various diseases at pre-disease states. Although dynamical network biomarker theory has been developed for pre-disease detection, mathematical frameworks for pre-disease treatment have not been well established. Here I propose a control theory-based approach for pre-disease treatment, named Markov chain sparse control (MCSC), where time evolution of a probability distribution on a Markov chain is described as a discrete-time linear system. By designing a sparse controller, a few candidate states for intervention are identified. The validity of MCSC is demonstrated using numerical simulations and real-data analysis.

math.OC

Branching embedding: A heuristic dimensionality reduction algorithm based on hierarchical clustering

This paper proposes a new dimensionality reduction algorithm named branching embedding (BE). It converts a dendrogram to a two-dimensional scatter plot, and visualizes the inherent structures of the original high-dimensional data. Since the conversion part is not computationally demanding, the BE algorithm would be beneficial for the case where hierarchical clustering is already performed. Numerical experiments revealed that the outputs of the algorithm moderately preserve the original hierarchical structures.

stat.ML