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Manar Abu Talib

Publications and source records attributed to Manar Abu Talib.

5 recordsLinked to original sources

Semi-Supervised Learning-Based Genetic Biomarkers Dataset for Multiple-Stage Hepatocellular Carcinoma Prediction

Liver cancer is a complex disease responsible for a high number of deaths across the globe each year, making automated solutions for liver cancer classification urgent. The most common form of liver cancer is hepatocellular carcinoma (HCC), accounting for over 90% of liver cancer cases. There is a distinct lack of publicly available HCC datasets utilizing genomic data, which is necessary for training artificial intelligence (AI) models for automated HCC classification. This study proposes constructing a multi-stage HCC dataset using XGBoost and Semi-Supervised learning on three separate datasets of genomic biomarkers, utilizing their existing labels in the Semi-Supervised learning process to label the proposed dataset. The proposed dataset consists of 770 patient samples in total, categorized into five classes that represent normal tissue alongside different stages of HCC. Each sample in the dataset consists of 11,150 different gene expression levels. The XGBoost model demonstrated a final classification accuracy of 96.5% during the Semi-Supervised learning process.

cs.AI

Multimodal Cultural Heritage Architectural Style Classification for Residential Buildings in the UAE Based on CLIP Embeddings and SVM

The analysis and classification of cultural heritage architectural styles remain challenging due to the complexity of visual images of buildings, which are highly relied on in traditional CNN-based classification approaches in comparison to textual descriptions, and the relative lack of non-western region-specific datasets. This paper addresses this gap by proposing a multimodal machine learning framework to analyze and classify Emirati residential architecture using OpenAI's CLIP model. We integrate visual features from images and textual features from expert descriptions into a unified 512-dimensional embedding, followed by dimensionality reduction with UMAP for visualization and unsupervised clustering using K-Means. Cluster labels, which are derived from manual analysis of the K-Means clusters, are used to train an SVM classifier for automated architectural style classification. Our approach achieves a classification accuracy of 98% across eight identified style clusters, higher than every other study in the literature, demonstrating the effectiveness of combining visual and textual modalities. Overall, this paper highlights the potential of using multimodal AI to support architectural heritage analysis, offering scalable and interpretable tools for exploring regional architectural identities.

cs.CV

Potential of Artificial Intelligence Algorithms for Identification of Relevant Diagnostic and Prognostic Biomarkers of Early-Stage Liver Cancer

This study explores the use of deep learning and explainable artificial intelligence to diagnose hepatocellular carcinoma (HCC) and define effective biomarkers across five different stages of disease development using a transcriptomic biomarker HCC dataset constructed via semi-supervised learning from three source datasets. Several deep learning experiments were conducted with different feature extraction techniques and gene sets to identify the most effective features for training high-accuracy models with minimal loss. The best-performing model, using 15 selected genes with the SelectKBest algorithm, achieved 90.74% accuracy, while the model with the lowest recorded loss of 0.3187 was obtained using 20 selected genes. To address the issue of class imbalance in the dataset, a weighted training approach was conducted, and for model transparency and interpretability a SHAP-based XAI analysis provided insights into the model's decision-making, consistently finding DNAJB14 as the most influential gene. Functional validation in this study has provided compelling evidence that DNAJB14 plays an important role in the adverse properties of HCC and that its inhibition effectively reverses tumour cell migration, invasion, colony and sphere formation. The main limitation of this study is the dataset's class imbalance, and while weighted training helped mitigate this, further research and additional data are needed to guarantee model generalizability. Future studies should also explore the influence of genetic variations, environmental factors, and clinical differences on model performance across diverse populations.

cs.AI

Breast cancer detection using artificial intelligence techniques: A systematic literature review

Cancer is one of the most dangerous diseases to humans, and yet no permanent cure has been developed for it. Breast cancer is one of the most common cancer types. According to the National Breast Cancer foundation, in 2020 alone, more than 276,000 new cases of invasive breast cancer and more than 48,000 non-invasive cases were diagnosed in the US. To put these figures in perspective, 64% of these cases are diagnosed early in the disease's cycle, giving patients a 99% chance of survival. Artificial intelligence and machine learning have been used effectively in detection and treatment of several dangerous diseases, helping in early diagnosis and treatment, and thus increasing the patient's chance of survival. Deep learning has been designed to analyze the most important features affecting detection and treatment of serious diseases. For example, breast cancer can be detected using genes or histopathological imaging. Analysis at the genetic level is very expensive, so histopathological imaging is the most common approach used to detect breast cancer. In this research work, we systematically reviewed previous work done on detection and treatment of breast cancer using genetic sequencing or histopathological imaging with the help of deep learning and machine learning. We also provide recommendations to researchers who will work in this field

eess.IV

Machine Learning Classifications of Coronary Artery Disease

Coronary Artery Disease (CAD) is one of the leading causes of death worldwide, and so it is very important to correctly diagnose patients with the disease. For medical diagnosis, machine learning is a useful tool, however features and algorithms must be carefully selected to get accurate classification. To this effect, three feature selection methods have been used on 13 input features from the Cleveland dataset with 297 entries, and 7 were selected. The selected features were used to train three different classifiers, which are SVM, Naïve Bayes and KNN using 10-fold cross-validation. The resulting models evaluated using Accuracy, Recall, Specificity and Precision. It is found that the Naïve Bayes classifier performs the best on this dataset and features, outperforming or matching SVM and KNN in all the four evaluation parameters used and achieving an accuracy of 84%.

cs.LG