arXiv subjects

Manuel J. Freire

Publications and source records attributed to Manuel J. Freire.

9 recordsLinked to original sources

arXiv2020

The Lorentz Force on Ions in Membrane Channels of Neurons as a Mechanism for Transcranial Static Magnetic Stimulation

Transcranial static magnetic stimulation is a novel noninvasive method of reduction of the cortical excitability in certain neurological diseases that, unlike ordinary transcranial magnetic stimulation, makes use of static magnetic fields generated by permanent magnets. The physical principle underlying transcranial magnetic stimulation is well known, that is, the Faradays law. By contrast, the physical mechanism that explains the interaction between neurons and static magnetic fields in transcranial static magnetic stimulation remains unclear, which makes it difficult to improve and fine tune the treatment. In the present work it is discussed the possibility that this mechanism might be the Lorentz force exerted on the ions flowing along the membrane channels of neurons. To support this hypothesis, a dimensional analysis it is carried out to compare the Larmor radius of the ions in the presence of a static magnetic field with the dimensions of the cross section of human axons and membrane channels in neurons. This analysis shows that whereas a moderate static magnetic field is not expected to affect the ion flux through axons, nevertheless it can affect the ion flux along membrane channels. The overall effect of the static magnetic field would be to introduce an additional friction between the ions and the walls of the membrane channels, thus reducing its conductance. Calculations performed by using a Hodgkin-Huxley model demonstrate that even a slight reduction of the conductance of the membrane channels can lead to the suppression of the action potential, thus inhibiting neuronal activity.

physics.med-ph↗

arXiv2016

Classical Physics and the Bounds of Quantum Correlations

A unifying principle explaining the numerical bounds of quantum correlations remains elusive despite the efforts devoted to identifying it. Here we show that these bounds are indeed not exclusive to quantum theory: for any abstract correlation scenario with compatible measurements, models based on classical waves produce probability distributions indistinguishable from those of quantum theory and, therefore, share the same bounds. We demonstrate this finding by implementing classical microwaves that propagate along meter-size transmission-line circuits and reproduce the probabilities of three emblematic quantum experiments. Our results show that the "quantum" bounds would also occur in a classical universe without quanta. The implications of this observation are discussed.

quant-ph↗

arXiv2011

Image acceleration in parallel magnetic resonance imaging by means of metamaterial magnetoinductive lenses

Parallel magnetic resonance imaging (MRI) is a technique of image acceleration which takes advantage of the localization of the field of view (FOV) of coils in an array. In this letter we show that metamaterial lenses based on capacitively-loaded rings can provide higher localization of the FOV. Several lens designs are systematically analyzed in order to find the structure providing higher signal-to-noise-ratio. The magnetoinductive (MI) lens is find to be the optimum structure and an experiment is developed to show it. The ability of the fabricated MI lenses to accelerate the image is quantified by means of the parameter known in the MRI community as g-factor.

physics.med-ph↗

arXiv2011

Active split-ring metamaterial slabs for magnetic resonance imaging

In this work, it is analyzed the ability of split-ring metamaterial slabs with zero/high permeability to reject/confine the radiofrequency magnetic field in magnetic resonance imaging systems. Using an homogenization procedure, split-ring slabs have been designed and fabricated to work in a 1.5T system. Active elements consisting of pairs of crossed diodes are inserted in the split-rings. With these elements, the permeability of the slabs can be automatically switched between a unity value when interacting with the strong excitation field of the transmitting body coil, and zero or high values when interacting with the weak field produced by protons in tissue. Experiments are shown for different configurations where these slabs can help to locally increase the signal-to-noise-ratio.

physics.med-ph↗

arXiv2009

On the applications of mu=-1 metamaterial lenses for magnetic resonance imaging

In this work some possible applications of negative permeability magnetic metamaterial lenses for magnetic resonance imaging (MRI) are analyzed. Metamaterials are artificial composites designed to have a given permittivity and/or permeability, including negative values for these constants. It is shown that using magnetic metamaterials lenses it is possible to manipulate the spatial distribution of the radio-frequency (RF) field used in MR systems and, under some circumstances, improve the sensitivity of surface coils. Furthermore a collimation of the RF field, phenomenon that may find application in parallel imaging, is presented. MR images of real tissues are shown in order to prove the suitability of the theoretical analysis for practical applications.

physics.med-ph↗

arXiv2009

Metamaterial radiofrequency lens for magnetic resonance imaging

The purpose of this work is to test the ability of a new class of passive electromagnetic device to increase the penetration depth of phased arrays of surface coils for magnetic resonance (MR) imaging systems. This new device is based on the emerging technology of metamaterials and behaves like a lens for the radiofrequency magnetic fields. The presented device was tested in several 1.5-T MR systems from different companies in combination with different phased arrays. One of the authors was enrolled as volunteer for the experiments. In these experiments his knees were imaged by using a dual phased array. The device was placed between the knees to check that the penetration depth of the coils was improved by this passive device. In all the experiments the presented device was successfully tested and it was checked that the knees of the volunteer can be imaged at deeper distances and that the signal-to-noise-ratio (SNR) in the obtained MR images was improved by the presence of the lens. The presented device has proven to increase the penetration depth of MR phased arrays of surface coils. The lens was tested by means of the MR imaging of the knees but it can be used to image any pair of joints simultaneously by placing it between the joints. The positive results suggest the possibility of using the lens to image the female breast. This would make it possible to increase the SNR without higher fields, thus fulfilling the safety regulations governing the standard absorption rate (SAR).

physics.med-ph↗

arXiv2008

Experimental demonstration of a mu=-1 metamaterial lens for magnetic resonance imaging

In this work a mu=-1 metamaterial (MM) lens for magnetic resonance imaging (MRI) is demonstrated. MRI uses surface coils to detect the radiofrequency(RF) energy absorbed and emitted by the nuclear spins in the imaged object. The proposed MM lens manipulates the RF field detected by these surface coils, so that the coil sensitivity and spatial localization is substantially improved. Beyond this specific application, we feel that the reported results are the experimental confirmation of a new concept for the manipulation of RF field in MRI, which paves the way to many other interesting applications.

physics.med-ph↗

arXiv2006

Near-field imaging in the megahertz range by strongly coupled magnetoinductive surfaces: theoretical model and experimental validation

In this work, near-field imaging by two strongly coupled arrays of split ring resonators is analyzed. A simple theoretical model is developed to obtain the transfer function of the lens. This model shows that magnetoinductive surface waves (MISWs) play the same role as plasmon-polaritons in negative refractive slabs. In particular, the model predicts that the image is formed near the resonant frequency of the rings, between the pass-bands for the two MISW branches that can be excited in the lens. It also predicts a significant image enhancement when the distance between the source source and the image plane is smaller than twice the lens width. The predictions of the theoretical model are supported by measurements in the radio-frequency range. This suggests the possibility of using this kind of devices to imaging processes in the megahertz range, as for example in magnetic resonance imaging.

physics.optics↗

arXiv2005

A planar magneto-inductive lens for three-dimensional subwavelength imaging

A planar near-field magnetoinductive lens operating in the microwave range is presented. The proposed device consists of two parallel planar arrays of metallic broadside coupled (BC-) split ring resonators (SRRs), or BC-SRRs. Power coming from a point-like source located in front of the lens is focused into a receiver located in free space behind the device. This focus is clearly removed from the back side of the lens, and has a size which is an order of magnitude smaller than the free space wavelength of the incoming radiation. The imaging properties of the device mainly relies on the excitation of magnetoinductive surface waves on the BC-SRR arrays. By simply scaling the BC-SRRs size, as well as the arrays periodicity, the frequency of operation of the device can be tuned over a wide frequency range. Thus the proposed design is potentially useful for many applications ranging from megahertzs to terahertzs.

physics.optics↗