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Manuel Kroiss

Publications and source records attributed to Manuel Kroiss.

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Launchpad: A Programming Model for Distributed Machine Learning Research

A major driver behind the success of modern machine learning algorithms has been their ability to process ever-larger amounts of data. As a result, the use of distributed systems in both research and production has become increasingly prevalent as a means to scale to this growing data. At the same time, however, distributing the learning process can drastically complicate the implementation of even simple algorithms. This is especially problematic as many machine learning practitioners are not well-versed in the design of distributed systems, let alone those that have complicated communication topologies. In this work we introduce Launchpad, a programming model that simplifies the process of defining and launching distributed systems that is specifically tailored towards a machine learning audience. We describe our framework, its design philosophy and implementation, and give a number of examples of common learning algorithms whose designs are greatly simplified by this approach.

cs.DC

Podracer architectures for scalable Reinforcement Learning

Supporting state-of-the-art AI research requires balancing rapid prototyping, ease of use, and quick iteration, with the ability to deploy experiments at a scale traditionally associated with production systems.Deep learning frameworks such as TensorFlow, PyTorch and JAX allow users to transparently make use of accelerators, such as TPUs and GPUs, to offload the more computationally intensive parts of training and inference in modern deep learning systems. Popular training pipelines that use these frameworks for deep learning typically focus on (un-)supervised learning. How to best train reinforcement learning (RL) agents at scale is still an active research area. In this report we argue that TPUs are particularly well suited for training RL agents in a scalable, efficient and reproducible way. Specifically we describe two architectures designed to make the best use of the resources available on a TPU Pod (a special configuration in a Google data center that features multiple TPU devices connected to each other by extremely low latency communication channels).

cs.LG

Reverb: A Framework For Experience Replay

A central component of training in Reinforcement Learning (RL) is Experience: the data used for training. The mechanisms used to generate and consume this data have an important effect on the performance of RL algorithms. In this paper, we introduce Reverb: an efficient, extensible, and easy to use system designed specifically for experience replay in RL. Reverb is designed to work efficiently in distributed configurations with up to thousands of concurrent clients. The flexible API provides users with the tools to easily and accurately configure the replay buffer. It includes strategies for selecting and removing elements from the buffer, as well as options for controlling the ratio between sampled and inserted elements. This paper presents the core design of Reverb, gives examples of how it can be applied, and provides empirical results of Reverb's performance characteristics.

cs.LG

What Can Learned Intrinsic Rewards Capture?

The objective of a reinforcement learning agent is to behave so as to maximise the sum of a suitable scalar function of state: the reward. These rewards are typically given and immutable. In this paper, we instead consider the proposition that the reward function itself can be a good locus of learned knowledge. To investigate this, we propose a scalable meta-gradient framework for learning useful intrinsic reward functions across multiple lifetimes of experience. Through several proof-of-concept experiments, we show that it is feasible to learn and capture knowledge about long-term exploration and exploitation into a reward function. Furthermore, we show that unlike policy transfer methods that capture "how" the agent should behave, the learned reward functions can generalise to other kinds of agents and to changes in the dynamics of the environment by capturing "what" the agent should strive to do.

cs.AI

Quantifying alternative splicing from paired-end RNA-sequencing data

RNA-sequencing has revolutionized biomedical research and, in particular, our ability to study gene alternative splicing. The problem has important implications for human health, as alternative splicing may be involved in malfunctions at the cellular level and multiple diseases. However, the high-dimensional nature of the data and the existence of experimental biases pose serious data analysis challenges. We find that the standard data summaries used to study alternative splicing are severely limited, as they ignore a substantial amount of valuable information. Current data analysis methods are based on such summaries and are hence suboptimal. Further, they have limited flexibility in accounting for technical biases. We propose novel data summaries and a Bayesian modeling framework that overcome these limitations and determine biases in a nonparametric, highly flexible manner. These summaries adapt naturally to the rapid improvements in sequencing technology. We provide efficient point estimates and uncertainty assessments. The approach allows to study alternative splicing patterns for individual samples and can also be the basis for downstream analyses. We found a severalfold improvement in estimation mean square error compared popular approaches in simulations, and substantially higher consistency between replicates in experimental data. Our findings indicate the need for adjusting the routine summarization and analysis of alternative splicing RNA-seq studies. We provide a software implementation in the R package casper.

stat.AP