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Marco Grangetto

Publications and source records attributed to Marco Grangetto.

At least 37 records · Page 2Linked to original sources

Unsupervised Learning of Unbiased Visual Representations

Deep neural networks often struggle to learn robust representations in the presence of dataset biases, leading to suboptimal generalization on unbiased datasets. This limitation arises because the models heavily depend on peripheral and confounding factors, inadvertently acquired during training. Existing approaches to address this problem typically involve explicit supervision of bias attributes or reliance on prior knowledge about the biases. In this study, we address the challenging scenario where no explicit annotations of bias are available, and there's no prior knowledge about its nature. We present a fully unsupervised debiasing framework with three key steps: firstly, leveraging the inherent tendency to learn malignant biases to acquire a bias-capturing model; next, employing a pseudo-labeling process to obtain bias labels; and finally, applying cutting-edge supervised debiasing techniques to achieve an unbiased model. Additionally, we introduce a theoretical framework for evaluating model biasedness and conduct a detailed analysis of how biases impact neural network training. Experimental results on both synthetic and real-world datasets demonstrate the effectiveness of our method, showcasing state-of-the-art performance in various settings, occasionally surpassing fully supervised debiasing approaches.

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STanH : Parametric Quantization for Variable Rate Learned Image Compression

In end-to-end learned image compression, encoder and decoder are jointly trained to minimize a $R + λD$ cost function, where $λ$ controls the trade-off between rate of the quantized latent representation and image quality. Unfortunately, a distinct encoder-decoder pair with millions of parameters must be trained for each $λ$, hence the need to switch encoders and to store multiple encoders and decoders on the user device for every target rate. This paper proposes to exploit a differentiable quantizer designed around a parametric sum of hyperbolic tangents, called STanH , that relaxes the step-wise quantization function. STanH is implemented as a differentiable activation layer with learnable quantization parameters that can be plugged into a pre-trained fixed rate model and refined to achieve different target bitrates. Experimental results show that our method enables variable rate coding with comparable efficiency to the state-of-the-art, yet with significant savings in terms of ease of deployment, training time, and storage costs

cs.CV↗

Boost Your NeRF: A Model-Agnostic Mixture of Experts Framework for High Quality and Efficient Rendering

Since the introduction of NeRFs, considerable attention has been focused on improving their training and inference times, leading to the development of Fast-NeRFs models. Despite demonstrating impressive rendering speed and quality, the rapid convergence of such models poses challenges for further improving reconstruction quality. Common strategies to improve rendering quality involves augmenting model parameters or increasing the number of sampled points. However, these computationally intensive approaches encounter limitations in achieving significant quality enhancements. This study introduces a model-agnostic framework inspired by Sparsely-Gated Mixture of Experts to enhance rendering quality without escalating computational complexity. Our approach enables specialization in rendering different scene components by employing a mixture of experts with varying resolutions. We present a novel gate formulation designed to maximize expert capabilities and propose a resolution-based routing technique to effectively induce sparsity and decompose scenes. Our work significantly improves reconstruction quality while maintaining competitive performance.

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GABIC: Graph-based Attention Block for Image Compression

While standardized codecs like JPEG and HEVC-intra represent the industry standard in image compression, neural Learned Image Compression (LIC) codecs represent a promising alternative. In detail, integrating attention mechanisms from Vision Transformers into LIC models has shown improved compression efficiency. However, extra efficiency often comes at the cost of aggregating redundant features. This work proposes a Graph-based Attention Block for Image Compression (GABIC), a method to reduce feature redundancy based on a k-Nearest Neighbors enhanced attention mechanism. Our experiments show that GABIC outperforms comparable methods, particularly at high bit rates, enhancing compression performance.

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WiGNet: Windowed Vision Graph Neural Network

In recent years, Graph Neural Networks (GNNs) have demonstrated strong adaptability to various real-world challenges, with architectures such as Vision GNN (ViG) achieving state-of-the-art performance in several computer vision tasks. However, their practical applicability is hindered by the computational complexity of constructing the graph, which scales quadratically with the image size. In this paper, we introduce a novel Windowed vision Graph neural Network (WiGNet) model for efficient image processing. WiGNet explores a different strategy from previous works by partitioning the image into windows and constructing a graph within each window. Therefore, our model uses graph convolutions instead of the typical 2D convolution or self-attention mechanism. WiGNet effectively manages computational and memory complexity for large image sizes. We evaluate our method in the ImageNet-1k benchmark dataset and test the adaptability of WiGNet using the CelebA-HQ dataset as a downstream task with higher-resolution images. In both of these scenarios, our method achieves competitive results compared to previous vision GNNs while keeping memory and computational complexity at bay. WiGNet offers a promising solution toward the deployment of vision GNNs in real-world applications. We publicly released the code at https://github.com/EIDOSLAB/WiGNet.

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Multi-target stain normalization for histology slides

Traditional staining normalization approaches, e.g. Macenko, typically rely on the choice of a single representative reference image, which may not adequately account for the diverse staining patterns of datasets collected in practical scenarios. In this study, we introduce a novel approach that leverages multiple reference images to enhance robustness against stain variation. Our method is parameter-free and can be adopted in existing computational pathology pipelines with no significant changes. We evaluate the effectiveness of our method through experiments using a deep-learning pipeline for automatic nuclei segmentation on colorectal images. Our results show that by leveraging multiple reference images, better results can be achieved when generalizing to external data, where the staining can widely differ from the training set.

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AI-Assisted Diagnosis for Covid-19 CXR Screening: From Data Collection to Clinical Validation

In this paper, we present the major results from the Covid Radiographic imaging System based on AI (Co.R.S.A.) project, which took place in Italy. This project aims to develop a state-of-the-art AI-based system for diagnosing Covid-19 pneumonia from Chest X-ray (CXR) images. The contributions of this work are manyfold: the release of the public CORDA dataset, a deep learning pipeline for Covid-19 detection, and the clinical validation of the developed solution by expert radiologists. The proposed detection model is based on a two-step approach that, paired with state-of-the-art debiasing, provides reliable results. Most importantly, our investigation includes the actual usage of the diagnosis aid tool by radiologists, allowing us to assess the real benefits in terms of accuracy and time efficiency. Project homepage: https://corsa.di.unito.it/

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Domain Adaptation for Learned Image Compression with Supervised Adapters

In Learned Image Compression (LIC), a model is trained at encoding and decoding images sampled from a source domain, often outperforming traditional codecs on natural images; yet its performance may be far from optimal on images sampled from different domains. In this work, we tackle the problem of adapting a pre-trained model to multiple target domains by plugging into the decoder an adapter module for each of them, including the source one. Each adapter improves the decoder performance on a specific domain, without the model forgetting about the images seen at training time. A gate network computes the weights to optimally blend the contributions from the adapters when the bitstream is decoded. We experimentally validate our method over two state-of-the-art pre-trained models, observing improved rate-distortion efficiency on the target domains without penalties on the source domain. Furthermore, the gate's ability to find similarities with the learned target domains enables better encoding efficiency also for images outside them.

cs.CV↗

Detection of subclinical atherosclerosis by image-based deep learning on chest x-ray

Aims. To develop a deep-learning based system for recognition of subclinical atherosclerosis on a plain frontal chest x-ray. Methods and Results. A deep-learning algorithm to predict coronary artery calcium (CAC) score (the AI-CAC model) was developed on 460 chest x-ray (80% training cohort, 20% internal validation cohort) of primary prevention patients (58.4% male, median age 63 [51-74] years) with available paired chest x-ray and chest computed tomography (CT) indicated for any clinical reason and performed within 3 months. The CAC score calculated on chest CT was used as ground truth. The model was validated on an temporally-independent cohort of 90 patients from the same institution (external validation). The diagnostic accuracy of the AI-CAC model assessed by the area under the curve (AUC) was the primary outcome. Overall, median AI-CAC score was 35 (0-388) and 28.9% patients had no AI-CAC. AUC of the AI-CAC model to identify a CAC>0 was 0.90 in the internal validation cohort and 0.77 in the external validation cohort. Sensitivity was consistently above 92% in both cohorts. In the overall cohort (n=540), among patients with AI-CAC=0, a single ASCVD event occurred, after 4.3 years. Patients with AI-CAC>0 had significantly higher Kaplan Meier estimates for ASCVD events (13.5% vs. 3.4%, log-rank=0.013). Conclusion. The AI-CAC model seems to accurately detect subclinical atherosclerosis on chest x-ray with elevated sensitivity, and to predict ASCVD events with elevated negative predictive value. Adoption of the AI-CAC model to refine CV risk stratification or as an opportunistic screening tool requires prospective evaluation.

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Unbiased Supervised Contrastive Learning

Many datasets are biased, namely they contain easy-to-learn features that are highly correlated with the target class only in the dataset but not in the true underlying distribution of the data. For this reason, learning unbiased models from biased data has become a very relevant research topic in the last years. In this work, we tackle the problem of learning representations that are robust to biases. We first present a margin-based theoretical framework that allows us to clarify why recent contrastive losses (InfoNCE, SupCon, etc.) can fail when dealing with biased data. Based on that, we derive a novel formulation of the supervised contrastive loss (epsilon-SupInfoNCE), providing more accurate control of the minimal distance between positive and negative samples. Furthermore, thanks to our theoretical framework, we also propose FairKL, a new debiasing regularization loss, that works well even with extremely biased data. We validate the proposed losses on standard vision datasets including CIFAR10, CIFAR100, and ImageNet, and we assess the debiasing capability of FairKL with epsilon-SupInfoNCE, reaching state-of-the-art performance on a number of biased datasets, including real instances of biases in the wild.

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Contrastive learning for regression in multi-site brain age prediction

Building accurate Deep Learning (DL) models for brain age prediction is a very relevant topic in neuroimaging, as it could help better understand neurodegenerative disorders and find new biomarkers. To estimate accurate and generalizable models, large datasets have been collected, which are often multi-site and multi-scanner. This large heterogeneity negatively affects the generalization performance of DL models since they are prone to overfit site-related noise. Recently, contrastive learning approaches have been shown to be more robust against noise in data or labels. For this reason, we propose a novel contrastive learning regression loss for robust brain age prediction using MRI scans. Our method achieves state-of-the-art performance on the OpenBHB challenge, yielding the best generalization capability and robustness to site-related noise.

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To update or not to update? Neurons at equilibrium in deep models

Recent advances in deep learning optimization showed that, with some a-posteriori information on fully-trained models, it is possible to match the same performance by simply training a subset of their parameters. Such a discovery has a broad impact from theory to applications, driving the research towards methods to identify the minimum subset of parameters to train without look-ahead information exploitation. However, the methods proposed do not match the state-of-the-art performance, and rely on unstructured sparsely connected models. In this work we shift our focus from the single parameters to the behavior of the whole neuron, exploiting the concept of neuronal equilibrium (NEq). When a neuron is in a configuration at equilibrium (meaning that it has learned a specific input-output relationship), we can halt its update; on the contrary, when a neuron is at non-equilibrium, we let its state evolve towards an equilibrium state, updating its parameters. The proposed approach has been tested on different state-of-the-art learning strategies and tasks, validating NEq and observing that the neuronal equilibrium depends on the specific learning setup.

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Towards Efficient Capsule Networks

From the moment Neural Networks dominated the scene for image processing, the computational complexity needed to solve the targeted tasks skyrocketed: against such an unsustainable trend, many strategies have been developed, ambitiously targeting performance's preservation. Promoting sparse topologies, for example, allows the deployment of deep neural networks models on embedded, resource-constrained devices. Recently, Capsule Networks were introduced to enhance explainability of a model, where each capsule is an explicit representation of an object or its parts. These models show promising results on toy datasets, but their low scalability prevents deployment on more complex tasks. In this work, we explore sparsity besides capsule representations to improve their computational efficiency by reducing the number of capsules. We show how pruning with Capsule Network achieves high generalization with less memory requirements, computational effort, and inference and training time.

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Disentangling private classes through regularization

Deep learning models are nowadays broadly deployed to solve an incredibly large variety of tasks. However, little attention has been devoted to connected legal aspects. In 2016, the European Union approved the General Data Protection Regulation which entered into force in 2018. Its main rationale was to protect the privacy and data protection of its citizens by the way of operating of the so-called "Data Economy". As data is the fuel of modern Artificial Intelligence, it is argued that the GDPR can be partly applicable to a series of algorithmic decision making tasks before a more structured AI Regulation enters into force. In the meantime, AI should not allow undesired information leakage deviating from the purpose for which is created. In this work we propose DisP, an approach for deep learning models disentangling the information related to some classes we desire to keep private, from the data processed by AI. In particular, DisP is a regularization strategy de-correlating the features belonging to the same private class at training time, hiding the information of private classes membership. Our experiments on state-of-the-art deep learning models show the effectiveness of DisP, minimizing the risk of extraction for the classes we desire to keep private.

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HEMP: High-order Entropy Minimization for neural network comPression

We formulate the entropy of a quantized artificial neural network as a differentiable function that can be plugged as a regularization term into the cost function minimized by gradient descent. Our formulation scales efficiently beyond the first order and is agnostic of the quantization scheme. The network can then be trained to minimize the entropy of the quantized parameters, so that they can be optimally compressed via entropy coding. We experiment with our entropy formulation at quantizing and compressing well-known network architectures over multiple datasets. Our approach compares favorably over similar methods, enjoying the benefits of higher order entropy estimate, showing flexibility towards non-uniform quantization (we use Lloyd-max quantization), scalability towards any entropy order to be minimized and efficiency in terms of compression. We show that HEMP is able to work in synergy with other approaches aiming at pruning or quantizing the model itself, delivering significant benefits in terms of storage size compressibility without harming the model's performance.

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EnD: Entangling and Disentangling deep representations for bias correction

Artificial neural networks perform state-of-the-art in an ever-growing number of tasks, and nowadays they are used to solve an incredibly large variety of tasks. There are problems, like the presence of biases in the training data, which question the generalization capability of these models. In this work we propose EnD, a regularization strategy whose aim is to prevent deep models from learning unwanted biases. In particular, we insert an "information bottleneck" at a certain point of the deep neural network, where we disentangle the information about the bias, still letting the useful information for the training task forward-propagating in the rest of the model. One big advantage of EnD is that we do not require additional training complexity (like decoders or extra layers in the model), since it is a regularizer directly applied on the trained model. Our experiments show that EnD effectively improves the generalization on unbiased test sets, and it can be effectively applied on real-case scenarios, like removing hidden biases in the COVID-19 detection from radiographic images.

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Dysplasia grading of colorectal polyps through CNN analysis of WSI

Colorectal cancer is a leading cause of cancer death for both men and women. For this reason, histopathological characterization of colorectal polyps is the major instrument for the pathologist in order to infer the actual risk for cancer and to guide further follow-up. Colorectal polyps diagnosis includes the evaluation of the polyp type, and more importantly, the grade of dysplasia. This latter evaluation represents a critical step for the clinical follow-up. The proposed deep learning-based classification pipeline is based on state-of-the-art convolutional neural network, trained using proper countermeasures to tackle WSI high resolution and very imbalanced dataset. The experimental results show that one can successfully classify adenomas dysplasia grade with 70% accuracy, which is in line with the pathologists' concordance.

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UniToPatho, a labeled histopathological dataset for colorectal polyps classification and adenoma dysplasia grading

Histopathological characterization of colorectal polyps allows to tailor patients' management and follow up with the ultimate aim of avoiding or promptly detecting an invasive carcinoma. Colorectal polyps characterization relies on the histological analysis of tissue samples to determine the polyps malignancy and dysplasia grade. Deep neural networks achieve outstanding accuracy in medical patterns recognition, however they require large sets of annotated training images. We introduce UniToPatho, an annotated dataset of 9536 hematoxylin and eosin (H&E) stained patches extracted from 292 whole-slide images, meant for training deep neural networks for colorectal polyps classification and adenomas grading. We present our dataset and provide insights on how to tackle the problem of automatic colorectal polyps characterization.

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