arXiv subjects

Marco Pedersoli

Publications and source records attributed to Marco Pedersoli.

At least 91 records · Page 5Linked to original sources

arXiv2022

Negative Evidence Matters in Interpretable Histology Image Classification

Using only global image-class labels, weakly-supervised learning methods, such as class activation mapping, allow training CNNs to jointly classify an image, and locate regions of interest associated with the predicted class. However, without any guidance at the pixel level, such methods may yield inaccurate regions. This problem is known to be more challenging with histology images than with natural ones, since objects are less salient, structures have more variations, and foreground and background regions have stronger similarities. Therefore, computer vision methods for visual interpretation of CNNs may not directly apply. In this paper, a simple yet efficient method based on a composite loss is proposed to learn information from the fully negative samples (i.e., samples without positive regions), and thereby reduce false positives/negatives. Our new loss function contains two complementary terms: the first exploits positive evidence collected from the CNN classifier, while the second leverages the fully negative samples from training data. In particular, a pre-trained CNN is equipped with a decoder that allows refining the regions of interest. The CNN is exploited to collect both positive and negative evidence at the pixel level to train the decoder. Our method called NEGEV benefits from the fully negative samples that naturally occur in the data, without any additional supervision signals beyond image-class labels. Extensive experiments show that our proposed method can substantial outperform related state-of-art methods on GlaS (public benchmark for colon cancer), and Camelyon16 (patch-based benchmark for breast cancer using three different backbones). Our results highlight the benefits of using both positive and negative evidence, the first obtained from a classifier, and the other naturally available in datasets.

eess.IV↗

arXiv2022

Boundary-aware Information Maximization for Self-supervised Medical Image Segmentation

Unsupervised pre-training has been proven as an effective approach to boost various downstream tasks given limited labeled data. Among various methods, contrastive learning learns a discriminative representation by constructing positive and negative pairs. However, it is not trivial to build reasonable pairs for a segmentation task in an unsupervised way. In this work, we propose a novel unsupervised pre-training framework that avoids the drawback of contrastive learning. Our framework consists of two principles: unsupervised over-segmentation as a pre-train task using mutual information maximization and boundary-aware preserving learning. Experimental results on two benchmark medical segmentation datasets reveal our method's effectiveness in improving segmentation performance when few annotated images are available.

eess.IV↗

arXiv2021

A unifying mutual information view of metric learning: cross-entropy vs. pairwise losses

Recently, substantial research efforts in Deep Metric Learning (DML) focused on designing complex pairwise-distance losses, which require convoluted schemes to ease optimization, such as sample mining or pair weighting. The standard cross-entropy loss for classification has been largely overlooked in DML. On the surface, the cross-entropy may seem unrelated and irrelevant to metric learning as it does not explicitly involve pairwise distances. However, we provide a theoretical analysis that links the cross-entropy to several well-known and recent pairwise losses. Our connections are drawn from two different perspectives: one based on an explicit optimization insight; the other on discriminative and generative views of the mutual information between the labels and the learned features. First, we explicitly demonstrate that the cross-entropy is an upper bound on a new pairwise loss, which has a structure similar to various pairwise losses: it minimizes intra-class distances while maximizing inter-class distances. As a result, minimizing the cross-entropy can be seen as an approximate bound-optimization (or Majorize-Minimize) algorithm for minimizing this pairwise loss. Second, we show that, more generally, minimizing the cross-entropy is actually equivalent to maximizing the mutual information, to which we connect several well-known pairwise losses. Furthermore, we show that various standard pairwise losses can be explicitly related to one another via bound relationships. Our findings indicate that the cross-entropy represents a proxy for maximizing the mutual information -- as pairwise losses do -- without the need for convoluted sample-mining heuristics. Our experiments over four standard DML benchmarks strongly support our findings. We obtain state-of-the-art results, outperforming recent and complex DML methods.

cs.LG↗

arXiv2021

Diversified Multi-prototype Representation for Semi-supervised Segmentation

This work considers semi-supervised segmentation as a dense prediction problem based on prototype vector correlation and proposes a simple way to represent each segmentation class with multiple prototypes. To avoid degenerate solutions, two regularization strategies are applied on unlabeled images. The first one leverages mutual information maximization to ensure that all prototype vectors are considered by the network. The second explicitly enforces prototypes to be orthogonal by minimizing their cosine distance. Experimental results on two benchmark medical segmentation datasets reveal our method's effectiveness in improving segmentation performance when few annotated images are available.

cs.CV↗

arXiv2021

F-CAM: Full Resolution Class Activation Maps via Guided Parametric Upscaling

Class Activation Mapping (CAM) methods have recently gained much attention for weakly-supervised object localization (WSOL) tasks. They allow for CNN visualization and interpretation without training on fully annotated image datasets. CAM methods are typically integrated within off-the-shelf CNN backbones, such as ResNet50. Due to convolution and pooling operations, these backbones yield low resolution CAMs with a down-scaling factor of up to 32, contributing to inaccurate localizations. Interpolation is required to restore full size CAMs, yet it does not consider the statistical properties of objects, such as color and texture, leading to activations with inconsistent boundaries, and inaccurate localizations. As an alternative, we introduce a generic method for parametric upscaling of CAMs that allows constructing accurate full resolution CAMs (F-CAMs). In particular, we propose a trainable decoding architecture that can be connected to any CNN classifier to produce highly accurate CAM localizations. Given an original low resolution CAM, foreground and background pixels are randomly sampled to fine-tune the decoder. Additional priors such as image statistics and size constraints are also considered to expand and refine object boundaries. Extensive experiments, over three CNN backbones and six WSOL baselines on the CUB-200-2011 and OpenImages datasets, indicate that our F-CAM method yields a significant improvement in CAM localization accuracy. F-CAM performance is competitive with state-of-art WSOL methods, yet it requires fewer computations during inference.

cs.CV↗

arXiv2021

Self-Paced Contrastive Learning for Semi-supervised Medical Image Segmentation with Meta-labels

Pre-training a recognition model with contrastive learning on a large dataset of unlabeled data has shown great potential to boost the performance of a downstream task, e.g., image classification. However, in domains such as medical imaging, collecting unlabeled data can be challenging and expensive. In this work, we propose to adapt contrastive learning to work with meta-label annotations, for improving the model's performance in medical image segmentation even when no additional unlabeled data is available. Meta-labels such as the location of a 2D slice in a 3D MRI scan or the type of device used, often come for free during the acquisition process. We use the meta-labels for pre-training the image encoder as well as to regularize a semi-supervised training, in which a reduced set of annotated data is used for training. Finally, to fully exploit the weak annotations, a self-paced learning approach is used to help the learning and discriminate useful labels from noise. Results on three different medical image segmentation datasets show that our approach: i) highly boosts the performance of a model trained on a few scans, ii) outperforms previous contrastive and semi-supervised approaches, and iii) reaches close to the performance of a model trained on the full data.

cs.CV↗

arXiv2021

Augmented Lagrangian Adversarial Attacks

Adversarial attack algorithms are dominated by penalty methods, which are slow in practice, or more efficient distance-customized methods, which are heavily tailored to the properties of the distance considered. We propose a white-box attack algorithm to generate minimally perturbed adversarial examples based on Augmented Lagrangian principles. We bring several algorithmic modifications, which have a crucial effect on performance. Our attack enjoys the generality of penalty methods and the computational efficiency of distance-customized algorithms, and can be readily used for a wide set of distances. We compare our attack to state-of-the-art methods on three datasets and several models, and consistently obtain competitive performances with similar or lower computational complexity.

cs.LG↗

arXiv2021

Context-aware virtual adversarial training for anatomically-plausible segmentation

Despite their outstanding accuracy, semi-supervised segmentation methods based on deep neural networks can still yield predictions that are considered anatomically impossible by clinicians, for instance, containing holes or disconnected regions. To solve this problem, we present a Context-aware Virtual Adversarial Training (CaVAT) method for generating anatomically plausible segmentation. Unlike approaches focusing solely on accuracy, our method also considers complex topological constraints like connectivity which cannot be easily modeled in a differentiable loss function. We use adversarial training to generate examples violating the constraints, so the network can learn to avoid making such incorrect predictions on new examples, and employ the Reinforce algorithm to handle non-differentiable segmentation constraints. The proposed method offers a generic and efficient way to add any constraint on top of any segmentation network. Experiments on two clinically-relevant datasets show our method to produce segmentations that are both accurate and anatomically-plausible in terms of region connectivity.

cs.CV↗

arXiv2021

Boosting Semi-supervised Image Segmentation with Global and Local Mutual Information Regularization

The scarcity of labeled data often impedes the application of deep learning to the segmentation of medical images. Semi-supervised learning seeks to overcome this limitation by exploiting unlabeled examples in the learning process. In this paper, we present a novel semi-supervised segmentation method that leverages mutual information (MI) on categorical distributions to achieve both global representation invariance and local smoothness. In this method, we maximize the MI for intermediate feature embeddings that are taken from both the encoder and decoder of a segmentation network. We first propose a global MI loss constraining the encoder to learn an image representation that is invariant to geometric transformations. Instead of resorting to computationally-expensive techniques for estimating the MI on continuous feature embeddings, we use projection heads to map them to a discrete cluster assignment where MI can be computed efficiently. Our method also includes a local MI loss to promote spatial consistency in the feature maps of the decoder and provide a smoother segmentation. Since mutual information does not require a strict ordering of clusters in two different assignments, we incorporate a final consistency regularization loss on the output which helps align the cluster labels throughout the network. We evaluate the method on four challenging publicly-available datasets for medical image segmentation. Experimental results show our method to outperform recently-proposed approaches for semi-supervised segmentation and provide an accuracy near to full supervision while training with very few annotated images.

cs.CV↗

arXiv2021

Self-paced and self-consistent co-training for semi-supervised image segmentation

Deep co-training has recently been proposed as an effective approach for image segmentation when annotated data is scarce. In this paper, we improve existing approaches for semi-supervised segmentation with a self-paced and self-consistent co-training method. To help distillate information from unlabeled images, we first design a self-paced learning strategy for co-training that lets jointly-trained neural networks focus on easier-to-segment regions first, and then gradually consider harder ones.This is achieved via an end-to-end differentiable loss inthe form of a generalized Jensen Shannon Divergence(JSD). Moreover, to encourage predictions from different networks to be both consistent and confident, we enhance this generalized JSD loss with an uncertainty regularizer based on entropy. The robustness of individual models is further improved using a self-ensembling loss that enforces their prediction to be consistent across different training iterations. We demonstrate the potential of our method on three challenging image segmentation problems with different image modalities, using small fraction of labeled data. Results show clear advantages in terms of performance compared to the standard co-training baselines and recently proposed state-of-the-art approaches for semi-supervised segmentation

cs.CV↗

arXiv2020

On the Texture Bias for Few-Shot CNN Segmentation

Despite the initial belief that Convolutional Neural Networks (CNNs) are driven by shapes to perform visual recognition tasks, recent evidence suggests that texture bias in CNNs provides higher performing models when learning on large labeled training datasets. This contrasts with the perceptual bias in the human visual cortex, which has a stronger preference towards shape components. Perceptual differences may explain why CNNs achieve human-level performance when large labeled datasets are available, but their performance significantly degrades in lowlabeled data scenarios, such as few-shot semantic segmentation. To remove the texture bias in the context of few-shot learning, we propose a novel architecture that integrates a set of Difference of Gaussians (DoG) to attenuate high-frequency local components in the feature space. This produces a set of modified feature maps, whose high-frequency components are diminished at different standard deviation values of the Gaussian distribution in the spatial domain. As this results in multiple feature maps for a single image, we employ a bi-directional convolutional long-short-term-memory to efficiently merge the multi scale-space representations. We perform extensive experiments on three well-known few-shot segmentation benchmarks -- Pascal i5, COCO-20i and FSS-1000 -- and demonstrate that our method outperforms state-of-the-art approaches in two datasets under the same conditions. The code is available at: https://github.com/rezazad68/fewshot-segmentation

cs.CV↗

arXiv2020

Convolutional STN for Weakly Supervised Object Localization

Weakly supervised object localization is a challenging task in which the object of interest should be localized while learning its appearance. State-of-the-art methods recycle the architecture of a standard CNN by using the activation maps of the last layer for localizing the object. While this approach is simple and works relatively well, object localization relies on different features than classification, thus, a specialized localization mechanism is required during training to improve performance. In this paper, we propose a convolutional, multi-scale spatial localization network that provides accurate localization for the object of interest. Experimental results on CUB-200-2011 and ImageNet datasets show that our proposed approach provides competitive performance for weakly supervised localization.

cs.CV↗

arXiv2020

Learning Data Augmentation with Online Bilevel Optimization for Image Classification

Data augmentation is a key practice in machine learning for improving generalization performance. However, finding the best data augmentation hyperparameters requires domain knowledge or a computationally demanding search. We address this issue by proposing an efficient approach to automatically train a network that learns an effective distribution of transformations to improve its generalization. Using bilevel optimization, we directly optimize the data augmentation parameters using a validation set. This framework can be used as a general solution to learn the optimal data augmentation jointly with an end task model like a classifier. Results show that our joint training method produces an image classification accuracy that is comparable to or better than carefully hand-crafted data augmentation. Yet, it does not need an expensive external validation loop on the data augmentation hyperparameters.

cs.CV↗

arXiv2020

Temporal Stochastic Softmax for 3D CNNs: An Application in Facial Expression Recognition

Training deep learning models for accurate spatiotemporal recognition of facial expressions in videos requires significant computational resources. For practical reasons, 3D Convolutional Neural Networks (3D CNNs) are usually trained with relatively short clips randomly extracted from videos. However, such uniform sampling is generally sub-optimal because equal importance is assigned to each temporal clip. In this paper, we present a strategy for efficient video-based training of 3D CNNs. It relies on softmax temporal pooling and a weighted sampling mechanism to select the most relevant training clips. The proposed softmax strategy provides several advantages: a reduced computational complexity due to efficient clip sampling, and an improved accuracy since temporal weighting focuses on more relevant clips during both training and inference. Experimental results obtained with the proposed method on several facial expression recognition benchmarks show the benefits of focusing on more informative clips in training videos. In particular, our approach improves performance and computational cost by reducing the impact of inaccurate trimming and coarse annotation of videos, and heterogeneous distribution of visual information across time.

cs.CV↗

arXiv2020

Semi-supervised few-shot learning for medical image segmentation

Recent years have witnessed the great progress of deep neural networks on semantic segmentation, particularly in medical imaging. Nevertheless, training high-performing models require large amounts of pixel-level ground truth masks, which can be prohibitive to obtain in the medical domain. Furthermore, training such models in a low-data regime highly increases the risk of overfitting. Recent attempts to alleviate the need for large annotated datasets have developed training strategies under the few-shot learning paradigm, which addresses this shortcoming by learning a novel class from only a few labeled examples. In this context, a segmentation model is trained on episodes, which represent different segmentation problems, each of them trained with a very small labeled dataset. In this work, we propose a novel few-shot learning framework for semantic segmentation, where unlabeled images are also made available at each episode. To handle this new learning paradigm, we propose to include surrogate tasks that can leverage very powerful supervisory signals --derived from the data itself-- for semantic feature learning. We show that including unlabeled surrogate tasks in the episodic training leads to more powerful feature representations, which ultimately results in better generability to unseen tasks. We demonstrate the efficiency of our method in the task of skin lesion segmentation in two publicly available datasets. Furthermore, our approach is general and model-agnostic, which can be combined with different deep architectures.

cs.CV↗

arXiv2020

Progressive Gradient Pruning for Classification, Detection and DomainAdaptation

Although deep neural networks (NNs) have achievedstate-of-the-art accuracy in many visual recognition tasks,the growing computational complexity and energy con-sumption of networks remains an issue, especially for ap-plications on platforms with limited resources and requir-ing real-time processing. Filter pruning techniques haverecently shown promising results for the compression andacceleration of convolutional NNs (CNNs). However, thesetechniques involve numerous steps and complex optimisa-tions because some only prune after training CNNs, whileothers prune from scratch during training by integratingsparsity constraints or modifying the loss function.In this paper we propose a new Progressive GradientPruning (PGP) technique for iterative filter pruning dur-ing training. In contrast to previous progressive pruningtechniques, it relies on a novel filter selection criterion thatmeasures the change in filter weights, uses a new hard andsoft pruning strategy and effectively adapts momentum ten-sors during the backward propagation pass. Experimentalresults obtained after training various CNNs on image datafor classification, object detection and domain adaptationbenchmarks indicate that the PGP technique can achievea better trade-off between classification accuracy and net-work (time and memory) complexity than PSFP and otherstate-of-the-art filter pruning techniques.

cs.LG↗

arXiv2019

Deep clustering: On the link between discriminative models and K-means

In the context of recent deep clustering studies, discriminative models dominate the literature and report the most competitive performances. These models learn a deep discriminative neural network classifier in which the labels are latent. Typically, they use multinomial logistic regression posteriors and parameter regularization, as is very common in supervised learning. It is generally acknowledged that discriminative objective functions (e.g., those based on the mutual information or the KL divergence) are more flexible than generative approaches (e.g., K-means) in the sense that they make fewer assumptions about the data distributions and, typically, yield much better unsupervised deep learning results. On the surface, several recent discriminative models may seem unrelated to K-means. This study shows that these models are, in fact, equivalent to K-means under mild conditions and common posterior models and parameter regularization. We prove that, for the commonly used logistic regression posteriors, maximizing the $L_2$ regularized mutual information via an approximate alternating direction method (ADM) is equivalent to a soft and regularized K-means loss. Our theoretical analysis not only connects directly several recent state-of-the-art discriminative models to K-means, but also leads to a new soft and regularized deep K-means algorithm, which yields competitive performance on several image clustering benchmarks.

cs.LG↗

arXiv2019

Information based Deep Clustering: An experimental study

Recently, two methods have shown outstanding performance for clustering images and jointly learning the feature representation. The first, called Information Maximiz-ing Self-Augmented Training (IMSAT), maximizes the mutual information between input and clusters while using a regularization term based on virtual adversarial examples. The second, named Invariant Information Clustering (IIC), maximizes the mutual information between the clustering of a sample and its geometrically transformed version. These methods use mutual information in distinct ways and leverage different kinds of transformations. This work proposes a comprehensive analysis of transformation and losses for deep clustering, where we compare numerous combinations of these two components and evaluate how they interact with one another. Results suggest that mutual information between a sample and its transformed representation leads to state-of-the-art performance for deep clustering, especially when used jointly with geometrical and adversarial transformations.

cs.CV↗