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Maria Skoularidou

Publications and source records attributed to Maria Skoularidou.

5 recordsLinked to original sources

CountsDiff: A Diffusion Model on the Natural Numbers for Generation and Imputation of Count-Based Data

Diffusion models have excelled at generative tasks for both continuous and token-based domains, but their application to discrete ordinal data remains underdeveloped. We present CountsDiff, a diffusion framework designed to model distributions on the natural numbers. CountsDiff extends the Blackout diffusion framework by simplifying its formulation through a direct parameterization in terms of a survival probability schedule and an explicit loss weighting. This introduces flexibility through design parameters with direct analogues in existing diffusion modeling frameworks. Beyond this reparameterization, CountsDiff introduces features from modern diffusion models, previously absent in counts-based domains, including continuous-time training, classifier-free guidance, and churn/remasking reverse dynamics that allow non-monotone reverse trajectories. We propose an initial instantiation of CountsDiff and validate it on natural image datasets (CIFAR-10, CelebA), exploring the effects of the introduced design parameters in a complex, well-studied, and interpretable data domain. We then highlight biological count assays as a natural use case, evaluating CountsDiff on single-cell RNA-seq imputation in fetal and heart cell atlases. Remarkably, we find that even this simple instantiation matches or surpasses the performance of a state-of-the-art discrete generative model and leading scRNA-seq imputation methods, while leaving substantial headroom for further gains through optimized design choices in future work.

cs.LG

Position: Bayesian Deep Learning is Needed in the Age of Large-Scale AI

In the current landscape of deep learning research, there is a predominant emphasis on achieving high predictive accuracy in supervised tasks involving large image and language datasets. However, a broader perspective reveals a multitude of overlooked metrics, tasks, and data types, such as uncertainty, active and continual learning, and scientific data, that demand attention. Bayesian deep learning (BDL) constitutes a promising avenue, offering advantages across these diverse settings. This paper posits that BDL can elevate the capabilities of deep learning. It revisits the strengths of BDL, acknowledges existing challenges, and highlights some exciting research avenues aimed at addressing these obstacles. Looking ahead, the discussion focuses on possible ways to combine large-scale foundation models with BDL to unlock their full potential.

cs.LG

Bayesian Context Trees: Modelling and exact inference for discrete time series

We develop a new Bayesian modelling framework for the class of higher-order, variable-memory Markov chains, and introduce an associated collection of methodological tools for exact inference with discrete time series. We show that a version of the context tree weighting algorithm can compute the prior predictive likelihood exactly (averaged over both models and parameters), and two related algorithms are introduced, which identify the a posteriori most likely models and compute their exact posterior probabilities. All three algorithms are deterministic and have linear-time complexity. A family of variable-dimension Markov chain Monte Carlo samplers is also provided, facilitating further exploration of the posterior. The performance of the proposed methods in model selection, Markov order estimation and prediction is illustrated through simulation experiments and real-world applications with data from finance, genetics, neuroscience, and animal communication. The associated algorithms are implemented in the R package BCT.

stat.ME

Modeling Tabular data using Conditional GAN

Modeling the probability distribution of rows in tabular data and generating realistic synthetic data is a non-trivial task. Tabular data usually contains a mix of discrete and continuous columns. Continuous columns may have multiple modes whereas discrete columns are sometimes imbalanced making the modeling difficult. Existing statistical and deep neural network models fail to properly model this type of data. We design TGAN, which uses a conditional generative adversarial network to address these challenges. To aid in a fair and thorough comparison, we design a benchmark with 7 simulated and 8 real datasets and several Bayesian network baselines. TGAN outperforms Bayesian methods on most of the real datasets whereas other deep learning methods could not.

cs.LG

Estimating the Directed Information and Testing for Causality

The problem of estimating the directed information rate between two discrete processes $\{X_n\}$ and $\{Y_n\}$ via the plug-in (or maximum-likelihood) estimator is considered. When the joint process $\{(X_n,Y_n)\}$ is a Markov chain of a given memory length, the plug-in estimator is shown to be asymptotically Gaussian and to converge at the optimal rate $O(1/\sqrt{n})$ under appropriate conditions; this is the first estimator that has been shown to achieve this rate. An important connection is drawn between the problem of estimating the directed information rate and that of performing a hypothesis test for the presence of causal influence between the two processes. Under fairly general conditions, the null hypothesis, which corresponds to the absence of causal influence, is equivalent to the requirement that the directed information rate be equal to zero. In that case a finer result is established, showing that the plug-in converges at the faster rate $O(1/n)$ and that it is asymptotically $χ^2$-distributed. This is proved by showing that this estimator is equal to (a scalar multiple of) the classical likelihood ratio statistic for the above hypothesis test. Finally it is noted that these results facilitate the design of an actual likelihood ratio test for the presence or absence of causal influence.

cs.IT