arXiv subjects

Mariana Dalarsson

Publications and source records attributed to Mariana Dalarsson.

5 recordsLinked to original sources

arXiv2026

Microwave focusing with temporal interference for non-invasive deep brain stimulation

Deep Brain Stimulation (DBS) is an effective treatment for neurological disorders but requires invasive surgery. This work presents a method for non-invasive DBS, based on microwave focusing of amplitude-modulated electric fields using an external antenna array of magnetic point dipoles. The proposed method combines iterative time reversal (iTR) and temporal interference (TI) optimization to jointly address electromagnetic field focusing and physiologically relevant neural stimulation. Antenna element positions, orientations, frequencies, amplitudes, and phases are optimized to localize stimulation within a target region. The method is evaluated in an anatomically realistic voxel head model with heterogeneous and lossy tissue properties. Systematic numerical studies, including perturbation analysis and statistical evaluation, demonstrate consistent spatial localization and robustness across all reported configurations. Safety is quantified using specific absorption rate (SAR), ensuring compliance with exposure limits. The study further provides insight into the influence of key parameters on field behavior and the associated trade-offs between focality, penetration, and safety in physiologically relevant stimulation. To the authors knowledge, this is the first study to combine iTR and TI optimization for microwave-based DBS in a realistic voxel head model, establishing a promising framework for safe non-invasive deep brain stimulation.

physics.med-ph↗

arXiv2018

A parametric model for the changes in the complex valued conductivity of a lung during tidal breathing

Classical homogenization theory based on the Hashin-Shtrikman coated ellipsoids is used to model the changes in the complex valued conductivity (or admittivity) of a lung during tidal breathing. Here, the lung is modeled as a two-phase composite material where the alveolar air-filling corresponds to the inclusion phase. The theory predicts a linear relationship between the real and the imaginary parts of the change in the complex valued conductivity of a lung during tidal breathing, and where the loss cotangent of the change is approximately the same as of the effective background conductivity and hence easy to estimate. The theory is illustrated with numerical examples, as well as by using reconstructed Electrical Impedance Tomography (EIT) images based on clinical data from an ongoing study within the EU-funded CRADL project. The theory may be potentially useful for improving the imaging algorithms and clinical evaluations in connection with lung EIT for respiratory management and monitoring in neonatal intensive care units.

physics.bio-ph↗

arXiv2017

Absorption and optimal plasmonic resonances for small ellipsoidal particles in lossy media

A new simplified formula is derived for the absorption cross section of small dielectric ellipsoidal particles embedded in lossy media. The new expression leads directly to a closed form solution for the optimal conjugate match with respect to the surrounding medium, i.e., the optimal permittivity of the ellipsoidal particle that maximizes the absorption at any given frequency. This defines the optimal plasmonic resonance for the ellipsoid. The optimal conjugate match represents a metamaterial in the sense that the corresponding optimal permittivity function may have negative real part (inductive properties), and can not in general be implemented as a passive material over a given bandwidth. A necessary and sufficient condition is derived for the feasibility of tuning the Drude model to the optimal conjugate match at a single frequency, and it is found that all the prolate spheroids and some of the (not too flat) oblate spheroids can be tuned into optimal plasmonic resonance at any desired center frequency. Numerical examples are given to illustrate the analysis. Except for the general understanding of plasmonic resonances in lossy media, it is also anticipated that the new results can be useful for feasibility studies with e.g., the radiotherapeutic hyperthermia based methods to treat cancer based on electrophoretic heating in gold nanoparticle suspensions using microwave radiation.

physics.class-ph↗

arXiv2016

On the physical limitations for radio frequency absorption in gold nanoparticle suspensions

This paper presents a study on the physical limitations for radio frequency absorption in gold nanoparticle suspensions. A canonical spherical geometry is considered consisting of a spherical suspension of colloidal gold nanoparticles characterized as an arbitrary passive dielectric material which is immersed in an arbitrary lossy medium. A relative heating coefficient and a corresponding optimal near field excitation are defined taking the skin effect of the surrounding medium into account. For small particle suspensions the optimal excitation is an electric dipole field for which explicit asymptotic expressions are readily obtained. It is then proven that the optimal permittivity function yielding a maximal absorption inside the spherical suspension is a conjugate match with respect to the surrounding lossy material. For a surrounding medium consisting of a weak electrolyte solution the optimal conjugate match can then readily be realized at a single frequency, e.g., by tuning the parameters of a Drude model corresponding to the electrophoretic particle acceleration mechanism. As such, the conjugate match can also be regarded to yield an optimal plasmonic resonance. Finally, a convex optimization approach is used to investigate the realizability of a passive material to approximate the desired conjugate match over a finite bandwidth. The relation of the proposed approach to general Mie theory as well as to the approximation of metamaterials are discussed. Numerical examples are included to illustrate the ultimate potential of heating in a realistic scenario in the microwave regime.

physics.class-ph↗

arXiv2012

Analytical solution for wave propagation through a graded index interface between a right-handed and a left-handed material

We have investigated the transmission and reflection properties of structures incorporating left-handed materials with graded index of refraction. We present an exact analytical solution to Helmholtz' equation for a graded index profile changing according to a hyperbolic tangent function along the propagation direction. We derive expressions for the field intensity along the graded index structure, and we show excellent agreement between the analytical solution and the corresponding results obtained by accurate numerical simulations. Our model straightforwardly allows for arbitrary spectral dispersion.

physics.optics↗