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Mark J. Schnitzer

Publications and source records attributed to Mark J. Schnitzer.

4 recordsLinked to original sources

A ghost mechanism: An analytical model of abrupt learning in recurrent networks

Abrupt learning is a common phenomenon in recurrent neural networks (RNNs) trained on working memory tasks. In such cases, the networks develop transient slow regions in state space that extend the effective timescales of computation. However, the mechanisms driving sudden performance improvements and their causal role remain unclear. To address this gap, we introduce the ghost mechanism, a process by which dynamical systems exhibit transient slowdown near the remnant of a saddle-node bifurcation. By reducing the high-dimensional dynamics near ghost points, we derive a one-dimensional canonical form that analytically captures learning as a process controlled by a single scale parameter. Using this model, we study a form of abrupt learning emerging from ghost points and identify a critical learning rate that scales as an inverse power law with the timescale of the learned computation. Beyond this rate, learning collapses through two interacting modes: (i) vanishing gradients and (ii) oscillatory gradients near minima. These features can lock the system into high-confidence but incorrect predictions when parameter updates trigger a no-learning zone, a region of parameter space where gradients vanish. We validate these predictions in low-rank RNNs, where ghost points precede abrupt transitions, and further demonstrate their generality in full-rank RNNs trained on canonical working memory tasks. Our theory offers two approaches to address these learning difficulties: increasing trainable ranks stabilizes learning trajectories, while reducing output confidence mitigates entrapment in no-learning zones. Overall, the ghost mechanism reveals how the computational demands of a task constrain the optimization landscape, demonstrating that well-known learning difficulties in RNNs partly arise from the dynamical systems they must learn to implement.

cs.LG

Latent computing by biological neural networks: A dynamical systems framework

Although individual neurons and neural populations exhibit the phenomenon of representational drift, perceptual and behavioral outputs of many neural circuits can remain stable across time scales over which representational drift is substantial. These observations motivate a dynamical systems framework for neural network activity that focuses on the concept of \emph{latent processing units,} core elements for robust coding and computation embedded in collective neural dynamics. Our theoretical treatment of these latent processing units yields five key attributes of computing through neural network dynamics. First, neural computations that are low-dimensional can nevertheless generate high-dimensional neural dynamics. Second, the manifolds defined by neural dynamical trajectories exhibit an inherent coding redundancy as a direct consequence of the universal computing capabilities of the underlying dynamical system. Third, linear readouts or decoders of neural population activity can suffice to optimally subserve downstream circuits controlling behavioral outputs. Fourth, whereas recordings from thousands of neurons may suffice for near optimal decoding from instantaneous neural activity patterns, experimental access to millions of neurons may be necessary to predict neural ensemble dynamical trajectories across timescales of seconds. Fifth, despite the variable activity of single cells, neural networks can maintain stable representations of the variables computed by the latent processing units, thereby making computations robust to representational drift. Overall, our framework for latent computation provides an analytic description and empirically testable predictions regarding how large systems of neurons perform robust computations via their collective dynamics.

q-bio.NC

Understanding and controlling the geometry of memory organization in RNNs

Training recurrent neural networks (RNNs) is a high-dimensional process that requires updating numerous parameters. Therefore, it is often difficult to pinpoint the underlying learning mechanisms. To address this challenge, we propose to gain mechanistic insights into the phenomenon of \emph{abrupt learning} by studying RNNs trained to perform diverse short-term memory tasks. In these tasks, RNN training begins with an initial search phase. Following a long period of plateau in accuracy, the values of the loss function suddenly drop, indicating abrupt learning. Analyzing the neural computation performed by these RNNs reveals geometric restructuring (GR) in their phase spaces prior to the drop. To promote these GR events, we introduce a temporal consistency regularization that accelerates (bioplausible) training, facilitates attractor formation, and enables efficient learning in strongly connected networks. Our findings offer testable predictions for neuroscientists and emphasize the need for goal-agnostic secondary mechanisms to facilitate learning in biological and artificial networks.

q-bio.NC

Wide-field fluorescence lifetime imaging of neuron spiking and sub-threshold activity in vivo

The development of voltage-sensitive fluorescent probes suggests fluorescence lifetime as a promising readout for electrical activity in biological systems. Existing approaches fail to achieve the speed and sensitivity required for voltage imaging in neuroscience applications. Here we demonstrate that wide-field electro-optic fluorescence lifetime imaging (EO-FLIM) allows lifetime imaging at kHz frame acquisition rates, spatially resolving action potential propagation and sub-threshold neural activity in live adult Drosophila. Lifetime resolutions of $< 5$ ps at 1 kHz were achieved for single cell voltage recordings. Lifetime readout is limited by photon shot noise and the method provides strong rejection of motion artifacts and technical noise sources. Recordings revealed local transmembrane depolarizations, two types of spikes with distinct fluorescence lifetimes, and phase locking of spikes to an external mechanical stimulus.

physics.optics