arXiv subjects

Mark Keller

Publications and source records attributed to Mark Keller.

4 recordsLinked to original sources

arXiv2026

Design of a mission to measure the shape and substructure of the 511 keV gamma-ray line from the center of the Milky Way

The 511 keV electron-positron annihilation feature near the galactic center has been detected for more than half a century, yet its origin remains a mystery. In this paper, we describe a concept for a balloon-borne 511 keV $\gamma$-ray mission called the 511-Spectrometer Mission. The mission will use Transition-Edge Sensor (TES) arrays with thick metal absorbers that are thermally coupled to the TES. The strength of the approach is a projected energy resolution of 200 eV Full Width Half Maximum (FWHM) at 511 keV, enabling detailed studies of the shape and substructure of the 511 keV emission from the galactic center region. A first mission equipped with 8,192 $\gamma$-ray detectors and a fully active shield and collimator could detect the galactic center with ~35 $\sigma$ statistical significance. We present the mission concept as well as first results obtained with a prototype detector equipped with $1.35\times1.35\times2$ mm$^{3}$ Bi absorbers. The detector has a quantum efficiency of 15% for 511 keV photons in photoelectric effect interactions. In tests with a $^{137}$Cs source, these prototype detectors show an energy resolution of 525 eV FWHM at 662 keV. We end with a discussion of follow-up missions that use coded mask imaging, or use concentrating or focusing optics to scrutinize the sources of 511 keV $\gamma$-rays on smaller angular scales.

astro-ph.IM↗

arXiv2025

Vitessce Link: A Mixed Reality and 2D Display Hybrid Approach for Visual Analysis of 3D Tissue Maps

Advances in spatial omics and high-resolution imaging enable the creation of three-dimensional (3D) tissue maps that capture cellular organization and interactions in situ. While these data provide critical insights into tissue function and disease, their exploration is often constrained by tools limited to 2D displays or stereoscopic rendering without analytical integration. We present Vitessce Link, a web-based hybrid framework that unites a 3D stereoscopic view in mixed reality with a synchronized 2D display environment. Users can navigate volumetric data with intuitive hand gestures while controlling channels, filters, and derived data views through the Vitessce platform. Built on open standards and running entirely in the browser, Vitessce Link minimizes friction, supports integration with computational notebooks, and synchronizes interactions across devices via a lightweight WebSocket architecture. Case studies in nephrology and oncology demonstrate how the hybrid approach enhances segmentation evaluation, distance measurement, and interpretation of spatial relationships. Vitessce Link establishes a paradigm for integrative, web-native analysis of 3D tissue maps.

cs.HC↗

arXiv2025

A Critical Analysis of the Usage of Dimensionality Reduction in Four Domains

Dimensionality reduction is used as an important tool for unraveling the complexities of high-dimensional datasets in many fields of science, such as cell biology, chemical informatics, and physics. Visualizations of the dimensionally reduced data enable scientists to delve into the intrinsic structures of their datasets and align them with established hypotheses. Visualization researchers have thus proposed many dimensionality reduction methods and interactive systems designed to uncover latent structures. At the same time, different scientific domains have formulated guidelines or common workflows for using dimensionality reduction techniques and visualizations for their respective fields. In this work, we present a critical analysis of the usage of dimensionality reduction in scientific domains outside of computer science. First, we conduct a bibliometric analysis of 21,249 academic publications that use dimensionality reduction to observe differences in the frequency of techniques across fields. Next, we conduct a survey of a 71-paper sample from four fields: biology, chemistry, physics, and business. Through this survey, we uncover common workflows, processes, and usage patterns, including the mixed use of confirmatory data analysis to validate a dataset and projection method and exploratory data analysis to then generate more hypotheses. We also find that misinterpretations and inappropriate usage is common, particularly in the visual interpretation of the resulting dimensionally reduced view. Lastly, we compare our observations with recent works in the visualization community in order to match work within our community to potential areas of impact outside our community.

cs.HC↗

arXiv2018

Revealing the nature of the ultrafast magnetic phase transition in Ni by correlating extreme ultraviolet magneto-optic and photoemission spectroscopies

By correlating time- and angle-resolved photoemission and time-resolved transverse- magneto- optical Kerr effect measurements, both at extreme ultraviolet wavelengths, we uncover the universal nature of the ultrafast photoinduced magnetic phase transition in Ni. This allows us to explain the ultrafast magnetic response of Ni at all laser fluences - from a small reduction of the magnetization at low laser fluences, to complete quenching at high laser fluences. Both probe methods exhibit the same demagnetization and recovery timescales. We further show that the ultrafast demagnetization in Ni is indeed a magnetic phase transition that is launched within 20 fs, followed by demagnetization of the material within ~200 fs, and subsequent recovery of the magnetization on timescales ranging from 500 fs to >70 ps. We also provide evidence of two competing channels with two distinct timescales in the recovery process, that suggest the presence of coexisting phases in the material.

cond-mat.mtrl-sci↗