Mary Sagoe | Searcharxiv

arXiv2025

PerceptronCARE: A Deep Learning-Based Intelligent Teleophthalmology Application for Diabetic Retinopathy Diagnosis

Diabetic retinopathy is a leading cause of vision loss among adults and a major global health challenge, particularly in underserved regions. This study presents PerceptronCARE, a deep learning-based teleophthalmology application designed for automated diabetic retinopathy detection using retinal images. The system was developed and evaluated using multiple convolutional neural networks, including ResNet-18, EfficientNet-B0, and SqueezeNet, to determine the optimal balance between accuracy and computational efficiency. The final model classifies disease severity with an accuracy of 85.4%, enabling real-time screening in clinical and telemedicine settings. PerceptronCARE integrates cloud-based scalability, secure patient data management, and a multi-user framework, facilitating early diagnosis, improving doctor-patient interactions, and reducing healthcare costs. This study highlights the potential of AI-driven telemedicine solutions in expanding access to diabetic retinopathy screening, particularly in remote and resource-constrained environments.

cs.CV↗

arXiv2025

TransUNet-GradCAM: A Hybrid Transformer-U-Net with Self-Attention and Explainable Visualizations for Foot Ulcer Segmentation

Automated segmentation of diabetic foot ulcers (DFUs) plays a critical role in clinical diagnosis, therapeutic planning, and longitudinal wound monitoring. However, this task remains challenging due to the heterogeneous appearance, irregular morphology, and complex backgrounds associated with ulcer regions in clinical photographs. Traditional convolutional neural networks (CNNs), such as U-Net, provide strong localization capabilities but struggle to model long-range spatial dependencies due to their inherently limited receptive fields. To address this, we employ the TransUNet architecture, a hybrid framework that integrates the global attention mechanism of Vision Transformers (ViTs) into the U-Net structure. This combination allows the model to extract global contextual features while maintaining fine-grained spatial resolution. We trained the model on the public Foot Ulcer Segmentation Challenge (FUSeg) dataset using a robust augmentation pipeline and a hybrid loss function to mitigate class imbalance. On the internal validation set, the model achieved a Dice Similarity Coefficient (F1-score) of 0.8886 using an optimized threshold of 0.4843. Crucially, to assess generalizability, we performed external validation on two independent datasets: the AZH Wound Care Center dataset (n=278) and the Medetec dataset (n=152). Without any retraining, the model achieved Dice scores of 0.6209 and 0.7850, respectively, demonstrating robust zero-shot transferability to unseen clinical domains. Furthermore, clinical utility analysis revealed a strong correlation (Pearson r = 0.9749) between predicted and ground-truth wound areas. These outcomes demonstrate that our approach effectively integrates global and local feature extraction, offering a reliable, effective, and explainable solution for automated foot ulcer assessment.

eess.IV↗