arXiv subjects

Mathias Fink

Publications and source records attributed to Mathias Fink.

At least 37 records · Page 2Linked to original sources

arXiv2023

Iterative Interference Cancellation for Time Reversal Division Multiple Access

Time Reversal (TR) has been proposed as a competitive precoding strategy for low-complexity devices, relying on ultra-wideband waveforms. This transmit processing paradigm can address the need for low power and low complexity receivers, which is particularly important for the Internet of Things, since it shifts most of the communications signal processing complexity to the transmitter side. Due to its spatio-temporal focusing property, TR has also been used to design multiple access schemes for multi-user communications scenarios. However, in wideband time-division multiple access schemes, the signals received by users suffer from significant levels of inter-symbol interference as well as interference from uncoordinated users, which often require additional processing at the receiver side. This paper proposes an iterative TR scheme that aims to reduce the level of interference in wideband multi-user settings, while keeping the processing complexity only at the transmitter side. The performance of the proposed TR-based protocol is evaluated using analytical derivations. In addition, its superiority over the conventional Time Reversal Division Multiple Access (TRDMA) scheme is demonstrated through simulations as well as experimental measurements at $2.5$ GHz carrier frequency with variable bandwidth values.

cs.IT↗

arXiv2023

Subwavelength pulse focusing and perfect absorption in the Maxwell fisheye

Maxwell's fisheye is a paradigm for an absolute optical instrument with a refractive index deduced from the stereographic projection of a sphere on a plane. We investigate experimentally the dynamics of flexural waves in a thin plate with a thickness varying according to the Maxwell fisheye index profile and a clamped boundary. We demonstrate subwavelength focusing and temporal pulse compression at the image point. This is achieved by introducing a sink emitting a cancelling signal optimally shaped using a time-reversal procedure. Perfect absorption and outward going wave cancellation at the focus point are demonstrated. The time evolution of the kinetic energy stored inside the cavity reveals that the sink absorbs energy out of the plate ten times faster than the natural decay rate.

physics.class-ph↗

arXiv2023

Imaging the dynamics of cardiac fiber orientation in vivo using 3D Ultrasound Backscatter Tensor Imaging

The assessment of myocardial fiber disarray is of major interest for the study of the progression of myocardial disease. However, time-resolved imaging of the myocardial structure remains unavailable in clinical practice. In this study, we introduce 3D Backscatter Tensor Imaging (3D-BTI), an entirely novel ultrasound-based imaging technique that can map the myocardial fibers orientation and its dynamics with a temporal resolution of 10 ms during a single cardiac cycle, non-invasively and in vivo in entire volumes. 3D-BTI is based on ultrafast volumetric ultrasound acquisitions, which are used to quantify the spatial coherence of backscattered echoes at each point of the volume. The capability of 3D-BTI to map the fibers orientation was evaluated in vitro in 5 myocardial samples. The helicoidal transmural variation of fiber angles was in good agreement with the one obtained by histological analysis. 3D-BTI was then performed to map the fiber orientation dynamics in vivo in the beating heart of an open-chest sheep at a volume rate of 90 volumes/s. Finally, the clinical feasibility of 3D-BTI was shown on a healthy volunteer. These initial results indicate that 3D-BTI could become a fully non-invasive technique to assess myocardial disarray at the bedside of patients.

physics.med-ph↗

arXiv2022

Ultrasound Matrix Imaging-Part II: The distortion matrix for aberration correction over multiple isoplanatic patches

This is the second article in a series of two which report on a matrix approach for ultrasound imaging in heterogeneous media. This article describes the quantification and correction of aberration, i.e. the distortion of an image caused by spatial variations in the medium speed-of-sound. Adaptive focusing can compensate for aberration, but is only effective over a restricted area called the isoplanatic patch. Here, we use an experimentally-recorded matrix of reflected acoustic signals tosynthesize a set of virtual transducers. We then examine wave propagation between these virtual transducers and an arbitrary correction plane. Such wave-fronts consist of two components: (i) An ideal geometric wave-front linked to diffraction and the input focusing point, and; (ii) Phase distortions induced by the speed-of-sound variations. These distortions are stored in a so-called distortion matrix, the singular value decomposition of which gives access to an optimized focusing law at any point. We show that, by decoupling the aberrations undergone by the outgoing and incoming waves and applying an iterative strategy, compensation for even high-order and spatially-distributed aberrations can be achieved. After a numerical validation of the process, ultrasound matrix imaging (UMI) is applied to the in-vivo imaging of a gallbladder. A map of isoplanatic modes is retrieved and is shown to be strongly correlated with the arrangement of tissues constituting the medium. The corresponding focusing laws yield an ultrasound image with drastically improved contrast and transverse resolution. UMI thus provides a flexible and powerful route towards computational ultrasound.

eess.IV↗

arXiv2022

Ultrasound Matrix Imaging-Part I: The focused reflection matrix, the F-factor and the role of multiple scattering

This is the first article in a series of two dealing with a matrix approach for aberration quantification and correction in ultrasound imaging. Advanced synthetic beamforming relies on a double focusing operation at transmission and reception on each point of the medium. Ultrasound matrix imaging (UMI) consists in decoupling the location of these transmitted and received focal spots. The response between those virtual transducers form the so-called focused reflection matrix that actually contains much more information than a confocal ultrasound image. In this paper, a time-frequency analysis of this matrix is performed, which highlights the single and multiple scattering contributions as well as the impact of aberrations in the monochromatic and broadband regimes. Interestingly, this analysis enables the measurement of the incoherent input-output point spread function at any pixel of this image. A fitting process enables the quantification of the single scattering, multiple scattering and noise components in the image. From the single scattering contribution, a focusing criterion is defined, and its evolution used to quantify the amount of aberration throughout the ultrasound image. In contrast to the state-of-the-art coherence factor, this new indicator is robust to multiple scattering and electronic noise, thereby providing a contrasted map of the focusing quality at a much better transverse resolution. After a validation of the proof-of-concept based on time-domain simulations, UMI is applied to the in-vivo study of a human calf. Beyond this specific example, UMI opens a new route for speed-of-sound and scattering quantification in ultrasound imaging.

physics.app-ph↗

arXiv2022

Super-resolved imaging based on spatiotemporal wavefront shaping

A novel approach to improving the performances of confocal scanning imaging is proposed. We experimentally demonstrate its feasibility using acoustic waves. It relies on a new way to encode spatial information using the temporal dimension. By moving an emitter, used to insonify an object, along a circular path, we create a temporally modulated wavefield. Due to the cylindrical symmetry of the problem and its temporal periodicity, the spatiotemporal input field can be decomposed into harmonics corresponding to different spatial vortices, or topological charges. Acquiring the back-reflected waves with receivers which are also rotating, multiple images of the same object with different Point Spread Functions (PSFs) are obtained. Not only is the resolution improved compared to a standard confocal configuration, but the accumulation of information also allows building images beating the diffraction limit. The topological robustness of the approach promises good performances in real life conditions.

physics.optics↗

arXiv2022

Compact orthogonal view OCT: clinical exploration of human trabecular meshwork and cornea at cell resolution

Glaucoma remains among the leading causes of blindness despite many treatment options available today. Effective treatment requires early diagnosis, which is difficult to achieve with existing imaging technologies that detect the already inflicted irreversible posterior eye damage. One improved approach could be to detect the changes in trabecular meshwork of the anterior eye that precede the intraocular pressure buildup and vision loss. Here we report a device that enables in vivo exploration of trabecular meshwork at cell resolution. The instrument combines two orthogonal views: en face view of time-domain full-field OCT for high-resolution and cross-sectional view of spectral-domain OCT for aligning to the meshwork. The device resolves micron-level corneoscleral and uveal pores, meshwork beams and internal elastic fibers, ciliary body tendons and trabecular cell nuclei. Capable of detecting blockage of trabecular pores, orthogonal view OCT presents a promising solution to the long-standing problem of early glaucoma diagnosis. Future clinical adoption of the device is facilitated by the compact footprint and broad functionality that includes corneal imaging in healthy subjects and patients (with keratoconus, Fuchs endothelial dystrophy) using the same design.

physics.med-ph↗

arXiv2022

Time Reversal for 6G Spatiotemporal Focusing: Recent Experiments, Opportunities, and Challenges

Late visions and trends for the future sixth Generation (6G) of wireless communications advocate, among other technologies, towards the deployment of network nodes with extreme numbers of antennas and up to terahertz frequencies, as means to enable various immersive applications. However, these technologies impose several challenges in the design of radio-frequency front-ends and beamforming architectures, as well as of ultra-wideband waveforms and computationally efficient transceiver signal processing. In this article, we revisit the Time Reversal (TR) technique, which was initially experimented in acoustics, in the context of large-bandwidth 6G wireless communications, capitalizing on its high resolution spatiotemporal focusing realized with low complexity transceivers. We first overview representative state-of-the-art in TR-based wireless communications, identifying the key competencies and requirements of TR for efficient operation. Recent and novel experimental setups and results for the spatiotemporal focusing capability of TR at the carrier frequencies $2.5$, $36$, and $273$ GHz are then presented, demonstrating in quantitative ways the technique's effectiveness in these very different frequency bands, as well as the roles of the available bandwidth and the number of transmit antennas. We also showcase the TR potential for realizing low complexity multi-user communications. The opportunities arising from TR-based wireless communications as well as the challenges for finding their place in 6G networks, also in conjunction with other complementary candidate technologies, are highlighted.

cs.IT↗

arXiv2022

Experimental Validation of Time Reversal Multiple Access for UWB Wireless Communications Centered at the $273$ GHz Frequency

Ultra-high data rates with low-power consumption wireless communications and low-complexity receivers is one of the key requirements for the next 6-th Generation (6G) of communication networks. Sub-Terahertz (SubTHz) frequency bands can support Ultra-WideBand (UWB) communications and can thus offer unprecedented increase in the wireless network capacity, rendering those bands and relevant research a strong candidate technology for 6G. However, in contrast to millimeter-wave communications, the technological advances in subTHz transceivers are not yet completely mature. In this paper, we focus on the Time Reversal (TR) precoding scheme, which is a computationally simple and robust technique capable of focusing UWB waveforms on both time and space, by exploiting channel diversity when available. We design a novel experimental setup, including a THz link inside a waveguide and operating at the carrier frequency 273.6 GHz with 2 GHz transmission bandwidth, and deploy it to perform multi-user communications with simple modulation. Our results demonstrate large communication rates with only 3 mm space separation of the receiving antennas.

cs.IT↗

arXiv2022

Time Reversal Precoding at SubTHz Frequencies: Experimental Results on Spatiotemporal Focusing

Due to availability of large spectrum chunks, the sub-TeraHertz (subTHz) frequency band can support Ultra-WideBand (UWB) wireless communications, paving the way for unprecedented increase in the wireless network capacity. This fact is expected to be the next breakthrough for the upcoming sixth Generation (6G) standards. However, the technology of subTHz transceivers is not yet mature enough to apply the advanced signal processing currently being implemented for millimeter wave wireless communications. In this paper, we consider the Time Reversal (TR) precoding technique, which provides simple and robust processing capable to offer highly focalized in time and space UWB waveforms, exploiting the spatial diversity of wireless channels. We first investigate experimentally the performance of subTHz TR focusing in complex media inside a leaking reverberation cavity. We then combine TR with received spatial modulation to realize data communication using a simple non-coherent receiver with two antennas. Our results showcase the capability of TR to offer focusing in time in the order of few nanoseconds and in space in the order of less than 1 mm.

cs.IT↗

arXiv2021

Smart Radio Environments

This Roadmap takes the reader on a journey through the research in electromagnetic wave propagation control via reconfigurable intelligent surfaces. Meta-surface modelling and design methods are reviewed along with physical realisation techniques. Several wireless applications are discussed, including beam-forming, focusing, imaging, localisation, and sensing, some rooted in novel architectures for future mobile communications networks towards 6G.

physics.class-ph↗

arXiv2021

Optical phase modulation by natural eye movements: application to time-domain FF-OCT image retrieval

Eye movements are commonly seen as an obstacle to high-resolution ophthalmic imaging. In this context we study the natural axial movements of the in vivo human eye and show that they can be used to modulate the optical phase and retrieve tomographic images via time-domain full-field optical coherence tomography (TD-FF-OCT). This approach opens a path to a simplified ophthalmic TD-FF-OCT device, operating without the usual piezo motor-camera synchronization. The device demonstrates in vivo human corneal images under the different image retrieval schemes (2-phase and 4-phase) and different exposure times (3.5 ms, 10 ms, 20 ms). Data on eye movements, acquired with a 100 kHz spectral-domain OCT with axial eye tracking, are used to study the influence of ocular motion on the probability of capturing high-signal tomographic images without phase washout. The optimal combinations of camera acquisition speed and amplitude of piezo modulation are proposed and discussed.

physics.med-ph↗

arXiv2021

Freeze-dried microfluidic monodisperse microbubbles as a new generation of ultrasound contrast agents

In the paper, we succeeded to freeze-dry monodisperse microbubbles without degrading their size and acoustic properties. We used microfluidic technology to generate highly monodisperse (coefficient of variation, CV<5%) microbubbles and optimized their formulation along with a cryoprotectant. By using a specific technique of retrieval of the bubble, we showed that freeze-drying the microbubbles does not alter their size distribution. To compare the fundamental resonance properties of the bubbles, we performed backscattered acoustic characterization measurements. Our experimental results revealed that the freeze-drying process conserved the acoustic properties of the bubbles. The maximum backscattering power amplitude of fresh and freeze-dried monodisperse PVA bubbles was around ten eight times higher than that of SonoVue at a similar concentration in vitro. By solving the question of storage and transportation of monodisperse bubbles, our work facilitates their penetration in the domain of UCAs, for performing new tasks and developing novel non-invasive measurements, such as pressure, unaccessible to the existing commercialized bubbles.

physics.med-ph↗

arXiv2021

Static-to-dynamic field conversion with time-varying media

In this Letter, we theoretically demonstrate that a uniform static electric field distribution can be partially converted to radiation fields when a portion of the medium undergoes a temporal change of its permittivity. An in-depth theoretical investigation of this phenomenon is developed for a dielectric block with a step-like temporal change located inside a waveguide charged with a DC voltage source. Closed analytical expressions are derived for the radiated electric and magnetic fields. The exchange of energy between the electrostatic and electromagnetic fields is discussed. The reconciliation between the seemingly contradictory temporal and spatial boundary conditions for the electric and magnetic fields at the interface of the time-varying dielectric block is analyzed and elucidated. Our findings may provide an alternative solution for generating electromagnetic radiation based on time-varying media.

physics.optics↗

arXiv2021

Experimental demonstration of a mmWave passive access point extender based on a binary reconfigurable intelligent surface

As data rates demands are exploding, 5G will soon rely on mmWaves that offer much higher bandwidths. Yet at these frequencies, attenuation and diffraction of waves require point to point communications with beamforming base stations that are complex and power greedy. Furthermore, since any obstacle at these frequencies completely blocks the waves, the networks must be extremely dense, resulting in dramatic increase of its cost. One way to avoid this problem is to redirect beams coming from base stations at many locations with Reconfigurable Intelligent Surfaces, in order to increase their coverage even in cluttered environments. Here we describe and experimentally demonstrate a binary tunable metasurface operating at 28~GHz, based on standard PCB and off the shelves PIN diodes. We show that it can be used as a Reconfigurable Intelligent Surface that beamforms an incoming plane wave at a given angle to one or several outgoing plane waves at angles reconfigurable in real time. Most importantly we use this 20~cm$\times$20~cm reconfigurable Intelligent Surface alongside software defined radio and up/down converters at 28~GHz, and demonstrate a wireless link between an emitter and a receiver 10~meters away, in a non line of sight configuration, hence proving the validity of the approach.

physics.app-ph↗

arXiv2021

Manifestation of aberrations in full-field optical coherence tomography

We report on a theoretical model for image formation in full-field optical coherence tomography (FFOCT). Because the spatial incoherence of the illumination acts as a virtual confocal pinhole in FFOCT, its imaging performance is equivalent to a scanning time-gated coherent confocal microscope. In agreement with optical experiments enabling a precise control of aberrations, FFOCT is shown to have nearly twice the resolution of standard imaging at moderate aberration level. Beyond a rigorous study on the sensitivity of FFOCT with respect to aberrations, this theoretical model paves the way towards an optimized design of adaptive optics and \rev{computational tools} for high-resolution and deep imaging of biological tissues.

physics.optics↗

arXiv2021

Non invasive live imaging of a novel retinal pigment epithelium stress model with Dynamic Full-Field Optical Coherence Tomography

Retinal degenerative diseases lead to the blindness of millions of people around the world. In case of age-related macular degeneration (AMD), the atrophy of retinal pigment epithelium (RPE) precedes neural dystrophy. But as crucial as understanding both healthy and pathological RPE cell physiology is for those diseases, no current technique allows subcellular in vivo or in vitro live observation of this critical cell layer. To fill this gap, we propose dynamic full-field OCT (D-FFOCT) as a candidate for live observation of in vitro RPE phenotype. In this way, we monitored primary porcine and human stem cell-derived RPE cells in stress model conditions by performing scratch assays. In this study, we quantified wound healing parameters on the stressed RPE, and observed different cell phenotypes, displayed by the D-FFOCT signal. In order to decipher the subcellular contributions to these dynamic profiles, we performed immunohistochemistry to identify which organelles generate the signal and found mitochondria to be the main contributor to D-FFOCT contrast. Altogether, D-FFOCT appears to be an innovative method to follow degenerative disease evolution and could be an appreciated method in the future for live patient diagnostics and to direct treatment choice.

physics.bio-ph↗

arXiv2021

Choroidal vasculature imaging with laser Doppler holography

The choroid is a highly vascularized tissues supplying the retinal pigment epithelium and photoreceptors. Its implication in retinal diseases is gaining increasing interest. However, investigating the anatomy and flow of the choroid remains challenging. Here we show that laser Doppler holography provides high contrast imaging of choroidal vessels in humans, with a spatial resolution comparable to state of the art indocyanine green angiography and optical coherence tomography. Additionally, laser Doppler holography contributes to sort out choroidal arteries and veins by using a power Doppler spectral analysis. We thus demonstrate the potential of laser Doppler holography to improve our understanding of the anatomy and flow of the choroidal vascular network.

physics.med-ph↗