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Md Rafiqul Islam

Publications and source records attributed to Md Rafiqul Islam.

15 recordsLinked to original sources

Generative Artificial Intelligence in Bioinformatics: A Systematic Review of Models, Applications, and Methodological Advances

Generative artificial intelligence (GenAI) is transforming bioinformatics by advancing genomics, proteomics, transcriptomics, structural biology, and drug discovery. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses framework, this review addresses six research questions to evaluate influential GenAI strategies in terms of methodological innovation, predictive performance, specialization, limitations, and data use. RQ1 shows that GenAI supports sequence analysis, molecular design, and integrative data modelling, often outperforming traditional methods through improved pattern recognition and generation. RQ2 finds that specialized architectures generally outperform general-purpose models because of domain-specific pretraining and context-aware design. RQ3 identifies benefits in molecular analysis and biological data integration, including improved accuracy and reduced analytical error. RQ4 reports advances in structural modelling, functional prediction, and synthetic data generation, supported by established benchmarks. RQ5 highlights key limitations, including poor scalability, data bias, and restricted generalizability, and recommends stronger evaluation and biologically grounded modelling. RQ6 shows that molecular datasets, including UniProtKB and ProteinNet12, cellular datasets, including CELLxGENE and GTEx, and textual resources, including PubMedQA and OMIM, support model training and generalization. Overall, this review demonstrates the growing potential of GenAI to advance computational biology through more accurate, specialized, and integrative bioinformatics analysis.

cs.CL

Multi-Modal Semantic Segmentation of Electrolyzer Components for Sustainable Hydrogen Technologies: A Dual-Branch Deep Learning Approach

Accurate segmentation of electrolyzer materials is essential for automated disassembly, sustainable recycling, and circular manufacturing in hydrogen technologies. However, this task is challenging due to strong visual similarity between materials, spectral overlap, irregular shapes, and severe class imbalance. To address these challenges, we propose an AI-driven dual-branch framework, Hyperspectral-RGB Electrolyzer Materials Network (HREM-Net), that combines hyperspectral imaging (HSI) and RGB images for electrolyzer material segmentation. We implemented several innovative modules, including Efficient Channel Attention, Coordinate Attention, Mobile Inverted Bottleneck blocks, and Atrous Spatial Pyramid Pooling to capture spectral and spatial features from HSI, and RGB images. With an adaptive gated cross-modal fusion module and composite loss function, HREM-Net achieves a mean class accuracy of 91.66% and a mean Intersection over Union (mIoU) of 0.82 on the Electrolyzers-HSI dataset, outperforming baseline segmentation models. Cross-dataset validation on the PCB-Vision dataset demonstrates strong generalization with 96.91% accuracy and 0.93 mIoU. This work poses its potential as an industrial application to improve electrolyzer efficiency, thereby improving the predictive maintenance of hydrogen production.

cs.CV

A Physics-Informed, Behavior-Aware Digital Twin for Robust Multimodal Forecasting of Core Body Temperature in Precision Livestock Farming

Precision livestock farming requires accurate and timely heat stress prediction to ensure animal welfare and optimize farm management. This study presents a physics-informed digital twin (DT) framework combined with an uncertainty-aware, expert-weighted stacked ensemble for multimodal forecasting of Core Body Temperature (CBT) in dairy cattle. Using the high-frequency, heterogeneous MmCows dataset, the DT integrates an ordinary differential equation (ODE)-based thermoregulation model that simulates metabolic heat production and dissipation, a Gaussian process for capturing cow-specific deviations, a Kalman filter for aligning predictions with real-time sensor data, and a behavioral Markov chain that models activity-state transitions under varying environmental conditions. The DT outputs key physiological indicators, such as predicted CBT, heat stress probability, and behavioral state distributions are fused with raw sensor data and enriched through multi-scale temporal analysis and cross-modal feature engineering to form a comprehensive feature set. The predictive methodology is designed in a three-stage stacked ensemble, where stage 1 trains modality-specific LightGBM 'expert' models on distinct feature groups, stage 2 collects their predictions as meta-features, and at stage 3 Optuna-tuned LightGBM meta-model yields the final CBT forecast. Predictive uncertainty is quantified via bootstrapping and validated using Prediction Interval Coverage Probability (PICP). Ablation analysis confirms that incorporating DT-derived features and multimodal fusion substantially enhances performance. The proposed framework achieves a cross-validated R2 of 0.783, F1 score of 84.25% and PICP of 92.38% for 2-hour ahead forecasting, providing a robust, uncertainty-aware, and physically principled system for early heat stress detection and precision livestock management.

cs.CV

BioAutoML-NAS: An End-to-End AutoML Framework for Multimodal Insect Classification via Neural Architecture Search on Large-Scale Biodiversity Data

Insect classification is important for agricultural management and ecological research, as it directly affects crop health and production. However, this task remains challenging due to the complex characteristics of insects, class imbalance, and large-scale datasets. To address these issues, we propose BioAutoML-NAS, the first BioAutoML model using multimodal data, including images, and metadata, which applies neural architecture search (NAS) for images to automatically learn the best operations for each connection within each cell. Multiple cells are stacked to form the full network, each extracting detailed image feature representations. A multimodal fusion module combines image embeddings with metadata, allowing the model to use both visual and categorical biological information to classify insects. An alternating bi-level optimization training strategy jointly updates network weights and architecture parameters, while zero operations remove less important connections, producing sparse, efficient, and high-performing architectures. Extensive evaluation on the BIOSCAN-5M dataset demonstrates that BioAutoML-NAS achieves 96.81% accuracy, 97.46% precision, 96.81% recall, and a 97.05% F1 score, outperforming state-of-the-art transfer learning, transformer, AutoML, and NAS methods by approximately 16%, 10%, and 8% respectively. Further validation on the Insects-1M dataset obtains 93.25% accuracy, 93.71% precision, 92.74% recall, and a 93.22% F1 score. These results demonstrate that BioAutoML-NAS provides accurate, confident insect classification that supports modern sustainable farming.

cs.CV

A fine-grained attention and geometric correspondence model for musculoskeletal risk classification in athletes using multimodal visual and skeletal features

Musculoskeletal disorders pose significant risks to athletes, and early risk assessment is essential for prevention. However, most existing methods are designed for controlled settings and fail to reliably assess risk in complex environments due to their reliance on a single type of data. This research introduces ViSK-GAT (Visual-Skeletal Geometric Attention Transformer), a novel multimodal deep learning framework that classifies musculoskeletal risk using both visual and skeletal coordinate-based features. A custom multimodal dataset (MusDis-Sports) was created by combining images and skeletal coordinates, with each sample labeled into eight risk categories based on the Rapid Entire Body Assessment (REBA) system. ViSK-GAT integrates two innovative modules: the Fine-Grained Attention Module (FGAM), which refines intra-modal features through self-attention before fusion, and the Multimodal Geometric Correspondence Module (MGCM), which enhances cross-modal alignment between image features and coordinates. The model achieved robust performance, with all key metrics exceeding 93%. Probability distribution error metrics also showed a low Root Mean Squared Error (RMSE) of 0.1205 and a Mean Absolute Error (MAE) of 0.0156. ViSK-GAT consistently outperformed state-of-the-art (SOTA) deep learning backbones and showed its potential to advance artificial intelligence-driven musculoskeletal risk assessment and enable timely interventions in sports.

cs.CV

Mitigating hallucinations in healthcare LLMs with granular fact-checking and domain-specific adaptation

In healthcare, it is essential for any Large Language Model (LLM)-generated output to be reliable and accurate, particularly in cases involving decision-making and patient safety. However, the outputs are often unreliable in such critical areas due to the risk of hallucinated outputs from the LLMs. To address this issue, we propose a fact-checking module that operates independently of any LLM, along with a domain-specific summarization model designed to minimize hallucination rates. Our model is fine-tuned using Low-Rank Adaptation (LoRA) on the MIMIC-III dataset and is paired with the fact-checking module, which uses numerical tests for correctness and logical checks at a granular level through discrete logic in natural language processing (NLP) to validate facts against electronic health records (EHRs). We trained the LLM on the full MIMIC-III dataset. For evaluation of the fact-checking module, we sampled 104 summaries, extracted them into 3786 propositions, and used these as facts. The fact-checking module achieves a precision of 0.8904, a recall of 0.8234, and an F1-score of 0.8556. Additionally, the LLM summary achieves a ROUGE-1 score of 0.5797 and a BERTScore of 0.9120 for summary quality.

cs.CL

Assessing Generalisation Capability of Machine Learning Models for Intrusion Detection

The growth of networked and IoT systems has intensified cyber-security threats and exposed the limits of traditional signature-based intrusion detection. Although machine-learning-based intrusion detection systems often report strong benchmark performance, high ac- curacy within a single dataset does not necessarily guarantee reliable performance in unseen network environments. This study investigates the generalisation capability of supervised machine learning models for intrusion detection using UNSW-NB15 and TON_IoT. Random Forest, Logistic Regression, and Naive Bayes were evaluated under same-dataset and cross-dataset settings. Random Forest achieved the strongest same dataset performance, with 95.08% accuracy on UNSW-NB15 and 99.79% on TON_IoT, but performance dropped sharply in cross-dataset testing. When trained on UNSW-NB15 and tested on TON_IoT or vice versa, below 40% accuracy. These results reveal a significant generalisation gap in intrusion detection. We connect this challenge to affective computing and human-centric AI, where behavioural signal analysis, anomaly detection, domain shift, and context-sensitive modelling are also central. This framing highlights the need for adaptive, generalisable cyber-security models that can operate across changing network and IoT environments.

cs.CR

DeepAgent: A Dual Stream Multi Agent Fusion for Robust Multimodal Deepfake Detection

The increasing use of synthetic media, particularly deepfakes, is an emerging challenge for digital content verification. Although recent studies use both audio and visual information, most integrate these cues within a single model, which remains vulnerable to modality mismatches, noise, and manipulation. To address this gap, we propose DeepAgent, an advanced multi-agent collaboration framework that simultaneously incorporates both visual and audio modalities for the effective detection of deepfakes. DeepAgent consists of two complementary agents. Agent-1 examines each video with a streamlined AlexNet-based CNN to identify the symbols of deepfake manipulation, while Agent-2 detects audio-visual inconsistencies by combining acoustic features, audio transcriptions from Whisper, and frame-reading sequences of images through EasyOCR. Their decisions are fused through a Random Forest meta-classifier that improves final performance by taking advantage of the different decision boundaries learned by each agent. This study evaluates the proposed framework using three benchmark datasets to demonstrate both component-level and fused performance. Agent-1 achieves a test accuracy of 94.35% on the combined Celeb-DF and FakeAVCeleb datasets. On the FakeAVCeleb dataset, Agent-2 and the final meta-classifier attain accuracies of 93.69% and 81.56%, respectively. In addition, cross-dataset validation on DeepFakeTIMIT confirms the robustness of the meta-classifier, which achieves a final accuracy of 97.49%, and indicates a strong capability across diverse datasets. These findings confirm that hierarchy-based fusion enhances robustness by mitigating the weaknesses of individual modalities and demonstrate the effectiveness of a multi-agent approach in addressing diverse types of manipulations in deepfakes.

cs.CV

From Language to Action: A Review of Large Language Models as Autonomous Agents and Tool Users

The pursuit of human-level artificial intelligence (AI) has significantly advanced the development of autonomous agents and Large Language Models (LLMs). LLMs are now widely utilized as decision-making agents for their ability to interpret instructions, manage sequential tasks, and adapt through feedback. This review examines recent developments in employing LLMs as autonomous agents and tool users and comprises seven research questions. We only used the papers published between 2023 and 2025 in conferences of the A* and A rank and Q1 journals. A structured analysis of the LLM agents' architectural design principles, dividing their applications into single-agent and multi-agent systems, and strategies for integrating external tools is presented. In addition, the cognitive mechanisms of LLM, including reasoning, planning, and memory, and the impact of prompting methods and fine-tuning procedures on agent performance are also investigated. Furthermore, we evaluated current benchmarks and assessment protocols and have provided an analysis of 68 publicly available datasets to assess the performance of LLM-based agents in various tasks. In conducting this review, we have identified critical findings on verifiable reasoning of LLMs, the capacity for self-improvement, and the personalization of LLM-based agents. Finally, we have discussed ten future research directions to overcome these gaps.

cs.CL

HANS-Net: Hyperbolic Convolution and Adaptive Temporal Attention for Accurate and Generalizable Liver and Tumor Segmentation in CT Imaging

Accurate liver and tumor segmentation on abdominal CT images is critical for reliable diagnosis and treatment planning, but remains challenging due to complex anatomical structures, variability in tumor appearance, and limited annotated data. To address these issues, we introduce Hyperbolic-convolutions Adaptive-temporal-attention with Neural-representation and Synaptic-plasticity Network (HANS-Net), a novel segmentation framework that synergistically combines hyperbolic convolutions for hierarchical geometric representation, a wavelet-inspired decomposition module for multi-scale texture learning, a biologically motivated synaptic plasticity mechanism for adaptive feature enhancement, and an implicit neural representation branch to model fine-grained and continuous anatomical boundaries. Additionally, we incorporate uncertainty-aware Monte Carlo dropout to quantify prediction confidence and lightweight temporal attention to improve inter-slice consistency without sacrificing efficiency. Extensive evaluations of the LiTS dataset demonstrate that HANS-Net achieves a mean Dice score of 93.26%, an IoU of 88.09%, an average symmetric surface distance (ASSD) of 0.72 mm, and a volume overlap error (VOE) of 11.91%. Furthermore, cross-dataset validation on the AMOS 2022 dataset obtains an average Dice of 85.09%, IoU of 76.66%, ASSD of 19.49 mm, and VOE of 23.34%, indicating strong generalization across different datasets. These results confirm the effectiveness and robustness of HANS-Net in providing anatomically consistent, accurate, and confident liver and tumor segmentation.

eess.IV

Cryptocurrency Price Forecasting Using Machine Learning: Building Intelligent Financial Prediction Models

Cryptocurrency markets are experiencing rapid growth, but this expansion comes with significant challenges, particularly in predicting cryptocurrency prices for traders in the U.S. In this study, we explore how deep learning and machine learning models can be used to forecast the closing prices of the XRP/USDT trading pair. While many existing cryptocurrency prediction models focus solely on price and volume patterns, they often overlook market liquidity, a crucial factor in price predictability. To address this, we introduce two important liquidity proxy metrics: the Volume-To-Volatility Ratio (VVR) and the Volume-Weighted Average Price (VWAP). These metrics provide a clearer understanding of market stability and liquidity, ultimately enhancing the accuracy of our price predictions. We developed four machine learning models, Linear Regression, Random Forest, XGBoost, and LSTM neural networks, using historical data without incorporating the liquidity proxy metrics, and evaluated their performance. We then retrained the models, including the liquidity proxy metrics, and reassessed their performance. In both cases (with and without the liquidity proxies), the LSTM model consistently outperformed the others. These results underscore the importance of considering market liquidity when predicting cryptocurrency closing prices. Therefore, incorporating these liquidity metrics is essential for more accurate forecasting models. Our findings offer valuable insights for traders and developers seeking to create smarter and more risk-aware strategies in the U.S. digital assets market.

cs.LG

Analysis of child development facts and myths using text mining techniques and classification models

The rapid dissemination of misinformation on the internet complicates the decision-making process for individuals seeking reliable information, particularly parents researching child development topics. This misinformation can lead to adverse consequences, such as inappropriate treatment of children based on myths. While previous research has utilized text-mining techniques to predict child abuse cases, there has been a gap in the analysis of child development myths and facts. This study addresses this gap by applying text mining techniques and classification models to distinguish between myths and facts about child development, leveraging newly gathered data from publicly available websites. The research methodology involved several stages. First, text mining techniques were employed to pre-process the data, ensuring enhanced accuracy. Subsequently, the structured data was analysed using six robust Machine Learning (ML) classifiers and one Deep Learning (DL) model, with two feature extraction techniques applied to assess their performance across three different training-testing splits. To ensure the reliability of the results, cross-validation was performed using both k-fold and leave-one-out methods. Among the classification models tested, Logistic Regression (LR) demonstrated the highest accuracy, achieving a 90% accuracy with the Bag-of-Words (BoW) feature extraction technique. LR stands out for its exceptional speed and efficiency, maintaining low testing time per statement (0.97 microseconds). These findings suggest that LR, when combined with BoW, is effective in accurately classifying child development information, thus providing a valuable tool for combating misinformation and assisting parents in making informed decisions.

cs.CL

Churn Prediction via Multimodal Fusion Learning:Integrating Customer Financial Literacy, Voice, and Behavioral Data

In todays competitive landscape, businesses grapple with customer retention. Churn prediction models, although beneficial, often lack accuracy due to the reliance on a single data source. The intricate nature of human behavior and high dimensional customer data further complicate these efforts. To address these concerns, this paper proposes a multimodal fusion learning model for identifying customer churn risk levels in financial service providers. Our multimodal approach integrates customer sentiments financial literacy (FL) level, and financial behavioral data, enabling more accurate and bias-free churn prediction models. The proposed FL model utilizes a SMOGN COREG supervised model to gauge customer FL levels from their financial data. The baseline churn model applies an ensemble artificial neural network and oversampling techniques to predict churn propensity in high-dimensional financial data. We also incorporate a speech emotion recognition model employing a pre-trained CNN-VGG16 to recognize customer emotions based on pitch, energy, and tone. To integrate these diverse features while retaining unique insights, we introduced late and hybrid fusion techniques that complementary boost coordinated multimodal co learning. Robust metrics were utilized to evaluate the proposed multimodal fusion model and hence the approach validity, including mean average precision and macro-averaged F1 score. Our novel approach demonstrates a marked improvement in churn prediction, achieving a test accuracy of 91.2%, a Mean Average Precision (MAP) score of 66, and a Macro-Averaged F1 score of 54 through the proposed hybrid fusion learning technique compared with late fusion and baseline models. Furthermore, the analysis demonstrates a positive correlation between negative emotions, low FL scores, and high-risk customers.

cs.LG

How Do Organizations Seek Cyber Assurance? Investigations on the Adoption of the Common Criteria and Beyond

Cyber assurance, which is the ability to operate under the onslaught of cyber attacks and other unexpected events, is essential for organizations facing inundating security threats on a daily basis. Organizations usually employ multiple strategies to conduct risk management to achieve cyber assurance. Utilizing cybersecurity standards and certifications can provide guidance for vendors to design and manufacture secure Information and Communication Technology (ICT) products as well as provide a level of assurance of the security functionality of the products for consumers. Hence, employing security standards and certifications is an effective strategy for risk management and cyber assurance. In this work, we begin with investigating the adoption of cybersecurity standards and certifications by surveying 258 participants from organizations across various countries and sectors. Specifically, we identify adoption barriers of the Common Criteria through the designed questionnaire. Taking into account the seven identified adoption barriers, we show the recommendations for promoting cybersecurity standards and certifications. Moreover, beyond cybersecurity standards and certifications, we shed light on other risk management strategies devised by our participants, which provides directions on cybersecurity approaches for enhancing cyber assurance in organizations.

cs.CR

AutoCl : A Visual Interactive System for Automatic Deep Learning Classifier Recommendation Based on Models Performance

Nowadays, deep learning (DL) models being increasingly applied to various fields, people without technical expertise and domain knowledge struggle to find an appropriate model for their task. In this paper, we introduce AutoCl a visual interactive recommender system aimed at helping non-experts to adopt an appropriate DL classifier. Our system enables users to compare the performance and behavior of multiple classifiers trained with various hyperparameter setups as well as automatically recommends a best classifier with appropriate hyperparameter. We compare features of AutoCl against several recent AutoML systems and show that it helps non-experts better in choosing DL classifier. Finally, we demonstrate use cases for image classification using publicly available dataset to show the capability of our system.

cs.LG