SearcharxivSearch

arXiv subjects

Md. Rashadul Islam

Publications and source records attributed to Md. Rashadul Islam.

2 recordsLinked to original sources

ExoNet: Calibrated Multimodal Deep Learning for TESS Exoplanet Candidate Vetting using Phase-Folded Light Curves, Stellar Parameters, and Multi-Head Attention

The discovery of exoplanets at scale has become one of the defining data science challenges in modern astrophysics. NASA's Transiting Exoplanet Survey Satellite (TESS) had catalogued over 7,800 planet candidates by early 2026, yet confirmation stands at fewer than 720. This paper introduces ExoNet, a multimodal deep learning framework that jointly processes phase-folded global and local light curve views alongside stellar parameter features through a calibrated late-fusion architecture combining 1D Convolutional Neural Networks, 8-head Multi-Head Attention over temporal feature maps, and a residual fusion head with post-hoc Temperature Scaling calibration. Trained on 7,585 labeled Kepler Objects of Interest, ExoNet achieves Test AUC = 0.9549 and 86.3% accuracy. Applied to 4,720 verified unconfirmed TESS Planet Candidates with TOI-TIC cross-identification verified against the NASA Exoplanet Archive, the model yields 1,754 high-confidence signals, 52 habitable-zone candidates, and six Earth-sized habitable-zone targets below 1.6 Earth radii. TOI-5728.01 and TOI-6716.01 emerge as the most Earth-like unconfirmed candidates. Full ablation confirms each modality improves AUC. Code and catalog are openly released.

astro-ph.EP

Explainable Machine Learning Reveals 12-Fold Ucp1 Upregulation and Thermogenic Reprogramming in Female Mouse White Adipose Tissue After 37 Days of Microgravity: First AI/ML Analysis of NASA OSD-970

Microgravity induces profound metabolic adaptations in mammalian physiology, yet the molecular mechanisms governing thermogenesis in female white adipose tissue (WAT) remain poorly characterized. This paper presents the first machine learning (ML) analysis of NASA Open Science Data Repository (OSDR) dataset OSD-970, derived from the Rodent Research-1 (RR-1) mission. Using RT-qPCR data from 89 adipogenesis and thermogenesis pathway genes in gonadal WAT of 16 female C57BL/6J mice (8 flight, 8 ground control) following 37 days aboard the International Space Station (ISS), we applied differential expression analysis, multiple ML classifiers with Leave-One-Out Cross-Validation (LOO-CV), and Explainable AI via SHapley Additive exPlanations (SHAP). The most striking finding is a dramatic 12.21-fold upregulation of Ucp1 (Delta-Delta-Ct = -3.61, p = 0.0167) in microgravity-exposed WAT, accompanied by significant activation of the thermogenesis pathway (mean pathway fold-change = 3.24). The best-performing model (Random Forest with top-20 features) achieved AUC = 0.922, Accuracy = 0.812, and F1 = 0.824 via LOO-CV. SHAP analysis consistently ranked Ucp1 among the top predictive features, while Angpt2, Irs2, Jun, and Klf-family transcription factors emerged as dominant consensus classifiers. Principal component analysis (PCA) revealed clear separation between flight and ground samples, with PC1 explaining 69.1% of variance. These results suggest rapid thermogenic reprogramming in female WAT as a compensatory response to microgravity. This study demonstrates the power of explainable AI for re-analysis of newly released NASA space biology datasets, with direct implications for female astronaut health on long-duration missions and for Earth-based obesity and metabolic disease research.

cs.LG