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Md. Tanzim Hossain

Publications and source records attributed to Md. Tanzim Hossain.

8 recordsLinked to original sources

OncoVision: Integrating Mammography and Clinical Data through Attention-Driven Multimodal AI for Enhanced Breast Cancer Diagnosis

OncoVision is a privileged-information training framework that uses mammography images and clinical features during training and performs inference from mammographic images alone. Employing an attention-based encoder-decoder backbone, it jointly segments four regions of interest (masses, calcifications, axillary findings, and breast tissue) with accuracy exceeding the nnU-Net baseline and predicts ten structured clinical features, including BI-RADS category. We developed two late-fusion strategies, Independent and Dependent, that integrate imaging, radiomic, and clinical information during training to improve diagnostic precision and potentially reduce inter-observer variability. Radiomic features extracted from predicted masks provide shape, intensity, and texture descriptors that complement the learned CNN representations. We evaluated OncoVision in a retrospective multi-reader study with six board-certified radiologists, assessing diagnostic confidence, reading time, and segmentation accuracy with and without AI assistance. In a paired reader-assistance evaluation, OncoVision was associated with higher diagnostic confidence for junior and senior radiologists, reduced reading time by up to 61%, and achieved segmentation accuracy comparable to or exceeding that of radiologists for mass lesions. We operationalized OncoVision as a secure web application, now deployed at a partner hospital, that generates structured reports with dual-confidence scoring and attention-weighted visualizations for real-time diagnostic support. The platform is designed for integration into clinical workflows, with the goal of supporting screening access in underprivileged regions. By combining accurate segmentation with clinical intuition, OncoVision advances AI-assisted mammographic interpretation, offering a scalable and accessible approach to earlier and more consistent image interpretation.

cs.CV↗

Anatomy-Change-Aware Bidirectional Selective State-Space Memory for Clinically Deployed Thoracic Radiotherapy Auto-Contouring

We developed DAMM-Net++, a 2.5D architecture for thoracic OAR and target volume segmentation that addresses three persistent challenges in radiotherapy auto-contouring: inter-slice surface incoherence, systematic failure on small low-contrast targets, and the absence of per-case reliability signals. The central component is an anatomy-change-aware bidirectional selective state-space memory that models through-plane anatomical change and selectively propagates context along the axial slice sequence. A boundary-aware decoder sharpens near-surface predictions, and an uncertainty head provides calibrated per-voxel confidence for clinical triage. We evaluated 2,146 patients across four centers, an independent external cohort of 112 patients, and a multicenter reader study involving 17 radiation oncologists on 305 cases. The model achieves a mean Dice of 0.955 and HD95 of 3.78 mm, with the largest gains on low-contrast organs-at-risk (OARs) and target volumes where through-plane context is most critical. The uncertainty head is well-calibrated and supports case-level triage. In the reader study, AI assistance reduced contouring time by 75-80% across experience levels and raised junior-reader IoU from 0.861 to 0.925, matching the unedited model. External validation showed a modest internal-to-external drop (< 5%) with calibrated uncertainty transferring without recalibration. The complete deployment pipeline from DICOM ingestion to TPS-compatible RTSTRUCT export has been integrated into the clinical workflow at a partner hospital, where it is used to assist with contouring. These results suggest that anatomically motivated inter-slice memory, paired with uncertainty-guided review, offers a clinically viable path for thoracic auto-contouring.

eess.IV↗

BAT-RM: A Boundary-Aware Transformer with Region-Aware Multi-Directional Mamba for Clinically Deployed Cervical Cancer Radiotherapy Auto-Contouring

We present a clinically deployed end-to-end auto-contouring system for cervical cancer radiotherapy planning, anchored by the Boundary-Aware Transformer with Region-Aware Mamba (BAT-RM), a hybrid architecture that integrates Sobel-gated boundary attention, a linear-time, multi-directional Mamba module for long-range context, and a boundary-skeleton-guided fusion gate. This design achieves linear-time complexity for long-range context modeling, avoiding the quadratic cost of full spatial self-attention. The full pipeline spans multi-institutional data collection, rigorous inter-rater quality assurance, external validation in an independent cohort, and a web-based clinical interface natively compatible with Varian, RayStation, and Monaco. Against four baselines, BAT-RM achieves superior performance across seven anatomical classes, with statistically significant improvements in target volumes, including GTV and CTV, and in organs at risk such as the rectum and bladder. A prospective multi-center reader study involving 13 radiation oncologists demonstrated that AI assistance elevates junior oncologists' IoU from 0.899 to 0.965, approaching senior-level accuracy, while reducing contouring time by more than 80%. The system also reduced expert consultation rates and improved inter-reader consistency, reflecting gains in both efficiency and quality assurance. Following clinical deployment at a partner hospital, the system reduced patient wait times from days to hours without additional staffing, enabling same-day or next-day initiation of treatment for routine cases. BAT-RM demonstrates that a rigorous research pipeline, from data curation to clinical deployment, can translate directly into measurable patient benefit in resource-constrained settings where the demand for radiotherapy far exceeds specialist capacity.

eess.IV↗

ConvMambaNet: A Hybrid CNN-Mamba State Space Architecture for Accurate and Real-Time EEG Seizure Detection

Epilepsy is a chronic neurological disorder marked by recurrent seizures that can severely impact quality of life. Electroencephalography (EEG) remains the primary tool for monitoring neural activity and detecting seizures, yet automated analysis remains challenging due to the temporal complexity of EEG signals. This study introduces ConvMambaNet, a hybrid deep learning model that integrates Convolutional Neural Networks (CNNs) with the Mamba Structured State Space Model (SSM) to enhance temporal feature extraction. By embedding the Mamba-SSM block within a CNN framework, the model effectively captures both spatial and long-range temporal dynamics. Evaluated on the CHB-MIT Scalp EEG dataset, ConvMambaNet achieved a 99% accuracy and demonstrated robust performance under severe class imbalance. These results underscore the model's potential for precise and efficient seizure detection, offering a viable path toward real-time, automated epilepsy monitoring in clinical environments.

cs.CV↗

Pioneering Precision in Lumbar Spine MRI Segmentation with Advanced Deep Learning and Data Enhancement

This study presents an advanced approach to lumbar spine segmentation using deep learning techniques, focusing on addressing key challenges such as class imbalance and data preprocessing. Magnetic resonance imaging (MRI) scans of patients with low back pain are meticulously preprocessed to accurately represent three critical classes: vertebrae, spinal canal, and intervertebral discs (IVDs). By rectifying class inconsistencies in the data preprocessing stage, the fidelity of the training data is ensured. The modified U-Net model incorporates innovative architectural enhancements, including an upsample block with leaky Rectified Linear Units (ReLU) and Glorot uniform initializer, to mitigate common issues such as the dying ReLU problem and improve stability during training. Introducing a custom combined loss function effectively tackles class imbalance, significantly improving segmentation accuracy. Evaluation using a comprehensive suite of metrics showcases the superior performance of this approach, outperforming existing methods and advancing the current techniques in lumbar spine segmentation. These findings hold significant advancements for enhanced lumbar spine MRI and segmentation diagnostic accuracy.

eess.IV↗

Optimizing Universal Lesion Segmentation: State Space Model-Guided Hierarchical Networks with Feature Importance Adjustment

Deep learning has revolutionized medical imaging by providing innovative solutions to complex healthcare challenges. Traditional models often struggle to dynamically adjust feature importance, resulting in suboptimal representation, particularly in tasks like semantic segmentation crucial for accurate structure delineation. Moreover, their static nature incurs high computational costs. To tackle these issues, we introduce Mamba-Ahnet, a novel integration of State Space Model (SSM) and Advanced Hierarchical Network (AHNet) within the MAMBA framework, specifically tailored for semantic segmentation in medical imaging.Mamba-Ahnet combines SSM's feature extraction and comprehension with AHNet's attention mechanisms and image reconstruction, aiming to enhance segmentation accuracy and robustness. By dissecting images into patches and refining feature comprehension through self-attention mechanisms, the approach significantly improves feature resolution. Integration of AHNet into the MAMBA framework further enhances segmentation performance by selectively amplifying informative regions and facilitating the learning of rich hierarchical representations. Evaluation on the Universal Lesion Segmentation dataset demonstrates superior performance compared to state-of-the-art techniques, with notable metrics such as a Dice similarity coefficient of approximately 98% and an Intersection over Union of about 83%. These results underscore the potential of our methodology to enhance diagnostic accuracy, treatment planning, and ultimately, patient outcomes in clinical practice. By addressing the limitations of traditional models and leveraging the power of deep learning, our approach represents a significant step forward in advancing medical imaging technology.

eess.IV↗

Integrating Mamba Sequence Model and Hierarchical Upsampling Network for Accurate Semantic Segmentation of Multiple Sclerosis Legion

Integrating components from convolutional neural networks and state space models in medical image segmentation presents a compelling approach to enhance accuracy and efficiency. We introduce Mamba HUNet, a novel architecture tailored for robust and efficient segmentation tasks. Leveraging strengths from Mamba UNet and the lighter version of Hierarchical Upsampling Network (HUNet), Mamba HUNet combines convolutional neural networks local feature extraction power with state space models long range dependency modeling capabilities. We first converted HUNet into a lighter version, maintaining performance parity and then integrated this lighter HUNet into Mamba HUNet, further enhancing its efficiency. The architecture partitions input grayscale images into patches, transforming them into 1D sequences for processing efficiency akin to Vision Transformers and Mamba models. Through Visual State Space blocks and patch merging layers, hierarchical features are extracted while preserving spatial information. Experimental results on publicly available Magnetic Resonance Imaging scans, notably in Multiple Sclerosis lesion segmentation, demonstrate Mamba HUNet's effectiveness across diverse segmentation tasks. The model's robustness and flexibility underscore its potential in handling complex anatomical structures. These findings establish Mamba HUNet as a promising solution in advancing medical image segmentation, with implications for improving clinical decision making processes.

eess.IV↗

Frequency Limited $\mathcal{H}_2$ Optimal Model Reduction of Large-Scale Sparse Dynamical Systems

We mainly consider the frequency limited $\mathcal{H}_2$ optimal model order reduction of large-scale sparse generalized systems. For this purpose we need to solve two Sylvester equations. This paper proposes efficient algorithm to solve them efficiently. The ideas are also generalized to index-1 descriptor systems. Numerical experiments are carried out using Python Programming Language and the results are presented to demonstrate the approximation accuracy and computational efficiency of the proposed techniques.

math.OC↗